Membrane Transporter/Ion Channel
Membrane transporter and ion channel inhibitors are compounds that block the function of proteins responsible for the transport of ions, nutrients, and other molecules across cell membranes. These inhibitors are crucial for studying the regulation of cellular homeostasis, signal transduction, and neurotransmission. Membrane transporter and ion channel inhibitors are also important in developing treatments for disorders such as epilepsy, cardiovascular diseases, and metabolic syndromes. At CymitQuimica, we provide a diverse selection of high-quality membrane transporter and ion channel inhibitors to support your research in physiology, neuroscience, and pharmacology.
Subcategories of "Membrane Transporter/Ion Channel"
- ABC(3 products)
- ATPase(99 products)
- Adiponectin receptor(5 products)
- CFTR(66 products)
- CGRP Receptor(53 products)
- Calcium Channel(547 products)
- Chloride channel(54 products)
- GABA Receptor(369 products)
- Monoamine Transporter(30 products)
- Monocarboxylate transporter(18 products)
- NKCC(2 products)
- NPC1L1(3 products)
- Na-K-Cl cotransporter(10 products)
- OAT(32 products)
- OCT(7 products)
- P-gp(55 products)
- Potassium Channel(289 products)
- Proton pump(41 products)
- SGLT(31 products)
- Sodium Channel(223 products)
- TRP/TRPV Channel(96 products)
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Found 2645 products of "Membrane Transporter/Ion Channel"
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TRPA1 Antagonist 3
CAS:TRPA1 Antagonist 3 is a compound with photoswitchable properties that acts as an agonist on the TRPA1 channel, providing the ability for optical control.Formula:C11H8ClN3Color and Shape:SolidMolecular weight:217.66UK-59811 hydrochloride
CAS:UK-59811 hydrochloride, Br-dihydropyridine derivative, blocks Ca V Ab channels in bacteria, IC50: 194 nM.Formula:C22H30BrClN2O5Color and Shape:SolidMolecular weight:517.85Margatoxin
CAS:KV1.3 channel blocker, IC50 36 pM, no effect on calcium-activated channels, hinders VEGF-induced Ca++ influx & NO in endothelial cells.Formula:C178H286N52O50S7Purity:98%Color and Shape:SolidMolecular weight:4178.96Ruzinurad
CAS:Ruzinurad (WO2020088641, compound I) is a potent URAT1 inhibitor, exhibiting high selectivity.Formula:C14H12BrNO2SColor and Shape:SolidMolecular weight:338.22Prilocaine acetate
Prilocaine acetate, an amino amide compound, functions as a Na/K-ATPase inhibitor, exhibiting neurotoxic effects [1] [2].Formula:C15H24N2O3Color and Shape:SolidMolecular weight:280.36AR-C141990 hydrochloride
CAS:AR-C141990 HCl inhibits MCT-1 (pKi 7.6) and MCT-2 (pKi 6.6), and has immunosuppressive effects.
Formula:C26H29ClN4O4SColor and Shape:SolidMolecular weight:529.05BuChE-IN-9
BuChE-IN-9 (compound 22a), an eqBuChE (equine serum-derived butyrylcholinesterase) inhibitor, exhibits potent activity with an IC50 of 173 nM.Formula:C28H34N4O2Color and Shape:SolidMolecular weight:458.6Dofetilide N-oxide
CAS:Dofetilide N-oxide (UK-116856) is a metabolite of dofetilide. Dofetilide can block potassium channels and is a tertiary antiarrhythmic drug.Formula:C19H27N3O6S2Purity:98%Color and Shape:SolidMolecular weight:457.56Oleoyl Serotonin
CAS:Oleoyl Serotonin is an antagonist of hTRPV1 with an IC50 of 2.57 μM.
Formula:C28H44N2O2Purity:99.88%Color and Shape:SolidMolecular weight:440.66EVT-401
EVT-401 (P2X7 receptor antagonist-1), a purinergic P2X7 receptor antagonist, demonstrates efficacy in combating neuroinflammation [1].Formula:C22H20F4N2O3Color and Shape:SolidMolecular weight:436.4UCL 1684 dibromide
CAS:apamin-sensitive Ca2+-activated K+ channel (KCa2.1) blockerFormula:C34H30Br2N4Purity:98%Color and Shape:SolidMolecular weight:654.45LU-32-176B
CAS:LU32-176B is a bioactive chemical.Formula:C23H24F2N2O2Color and Shape:SolidMolecular weight:398.45TRPV1 activator-2
CAS:TRPV1 activator-2 (Compound 9), a capsaicin head analog, engages in targeted interactions with channel residues at the lipid-water interface [1].Formula:C19H29NO3Color and Shape:SolidMolecular weight:319.44Carbonic anhydrase inhibitor 32
Carbonic anhydrase inhibitor32 (compound 5B) is an orally active, selective inhibitor of hCA (carbonic anhydrase) II/VII, with Ki values of 6.3 nM for hCA II, 10.1 nM for hCA VII, and 681 nM for hCA I. It shows potential for neuroprotection and anticonvulsant effects by reducing mTOR activation and increasing hippocampal KCC2 levels.Formula:C17H16N6O3SColor and Shape:SolidMolecular weight:384.41AVLX-125
CAS:AVLX-125 (UCCB01-125), a potent inhibitor of PSD-95 and PDZ domains, exhibits a dissociation constant (Kd) of 10 nM. It is utilized in researching inflammatory pain [1] [2].
Formula:C62H104N10O29Color and Shape:SolidMolecular weight:1453.54NF279
CAS:P2X1 antagonistFormula:C49H36N6Na6O23S6Purity:98%Color and Shape:SolidMolecular weight:1407.17AQP4 (205-215)
CAS:AQP4 (205-215) is a fragment of the water channel protein Aquaporin-4 (AQP4). This protein is an autoimmune antigen in optic neuromyelitis and, upon binding with CD40, is upregulated and presented in B cells. AQP4 is associated with neuromyelitis optica (NMO), an autoimmune inflammatory disease of the central nervous system (CNS).Formula:C48H75N13O17SColor and Shape:SolidMolecular weight:1138.25Mast cell degranulating peptide (28-49)
CAS:Mast cell degranulating peptide (28-49) is a bee venom depolarizer that can improve the cGMP content of cerebellum tablets in mice.
Formula:C110H196N40O24S4Purity:98%Color and Shape:SolidMolecular weight:2591.25Sulcardine 2HCl
CAS:Sulcardine 2HCl is a multi-ion channel blocker that blocks the properties of hERG and hNav1.5 channels and can be used to study atrial fibrillation.Formula:C24H35Cl2N3O4SPurity:99.33% - 99.76%Color and Shape:SoildMolecular weight:532.523NHE-1-IN-2
NHE-1-IN-2 (compound 7g) is a potent NHE-1 inhibitor with an IC50 of 0.78 μM. It mitigates left ventricular systolic dysfunction in mouse models of heart failure.Formula:C23H20ClN3O3Color and Shape:SolidMolecular weight:421.11932
