Membrane Transporter/Ion Channel
Membrane transporter and ion channel inhibitors are compounds that block the function of proteins responsible for the transport of ions, nutrients, and other molecules across cell membranes. These inhibitors are crucial for studying the regulation of cellular homeostasis, signal transduction, and neurotransmission. Membrane transporter and ion channel inhibitors are also important in developing treatments for disorders such as epilepsy, cardiovascular diseases, and metabolic syndromes. At CymitQuimica, we provide a diverse selection of high-quality membrane transporter and ion channel inhibitors to support your research in physiology, neuroscience, and pharmacology.
Subcategories of "Membrane Transporter/Ion Channel"
- ABC(3 products)
- ATPase(100 products)
- Adiponectin receptor(5 products)
- CFTR(66 products)
- CGRP Receptor(54 products)
- Calcium Channel(545 products)
- Chloride channel(53 products)
- GABA Receptor(369 products)
- Monoamine Transporter(30 products)
- Monocarboxylate transporter(18 products)
- NKCC(2 products)
- NPC1L1(3 products)
- Na-K-Cl cotransporter(10 products)
- OAT(32 products)
- OCT(7 products)
- P-gp(55 products)
- Potassium Channel(283 products)
- Proton pump(41 products)
- SGLT(31 products)
- Sodium Channel(219 products)
- TRP/TRPV Channel(96 products)
Show 13 more subcategories
Found 2586 products of "Membrane Transporter/Ion Channel"
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Sulcardine 2HCl
CAS:Sulcardine 2HCl is a multi-ion channel blocker that blocks the properties of hERG and hNav1.5 channels and can be used to study atrial fibrillation.Formula:C24H35Cl2N3O4SPurity:99.33% - 99.76%Color and Shape:SoildMolecular weight:532.523Chlorotoxin
CAS:Chlorotoxin: 36-amino acid peptide from deathstalker scorpion venom; blocks small chloride channels.
Formula:C158H249N53O47S11Purity:98%Color and Shape:SolidMolecular weight:3995.71Dofetilide N-oxide
CAS:Dofetilide N-oxide (UK-116856) is a metabolite of dofetilide. Dofetilide can block potassium channels and is a tertiary antiarrhythmic drug.Formula:C19H27N3O6S2Purity:98%Color and Shape:SolidMolecular weight:457.56UCL 1684 dibromide
CAS:apamin-sensitive Ca2+-activated K+ channel (KCa2.1) blockerFormula:C34H30Br2N4Purity:98%Color and Shape:SolidMolecular weight:654.45Mepivacaine hydrochloride
CAS:Mepivacaine hydrochloride (Mepivacaine HCl) is the hydrochloride salt form of mepivacaine, an amide derivative with local anesthetic properties.Formula:C15H22N2O·HClPurity:98.76% - 99.94%Color and Shape:White Or Off White Crystalline PowderMolecular weight:282.81Isotachysterol 3
CAS:Isotachysterol 3 boosts calcium transport in gut and bone mobilization in kidneyless rats.Formula:C27H44OColor and Shape:SolidMolecular weight:384.64(±)16-HETE
CAS:Electrolyte and fluid transport in the kidney are regulated in part by arachidonic acid and its metabolites.Formula:C20H32O3Color and Shape:SolidMolecular weight:320.473ω-Agatoxin IVA
CAS:Selective blocker of P-type calcium channels (IC50 < 1 - 3 nM). Also inhibits N-type channels at micromolar concentrations.Formula:C217H360N68O60S10Purity:98%Color and Shape:SolidMolecular weight:5202.25ABCB1-IN-1
ABCB1-IN-1 (compound 3) is a potent inhibitor of ABCB1 that promotes cell apoptosis.Formula:C36H33F3FeN2O4PSColor and Shape:SolidMolecular weight:733.54AChE/Aβ-IN-1
AChE/Aβ-IN-1 (compound 32) is a potent, orally active acetylcholinesterase (AChE) inhibitor with an IC50 of 86 nM and an NMDA receptor antagonist targeting theFormula:C20H25BrN4Color and Shape:SolidMolecular weight:401.34AQP4 (205-215)
CAS:AQP4 (205-215) is a fragment of the water channel protein Aquaporin-4 (AQP4). This protein is an autoimmune antigen in optic neuromyelitis and, upon binding with CD40, is upregulated and presented in B cells. AQP4 is associated with neuromyelitis optica (NMO), an autoimmune inflammatory disease of the central nervous system (CNS).Formula:C48H75N13O17SColor and Shape:SolidMolecular weight:1138.25Anticonvulsant agent 8
Anticonvulsant agent 8 (compound D4) is a chemical used in treating epilepsy by inhibiting GABAA currents. In mouse models, its ED50 values are 2.23 mg/kg for the maximal electroshock (MES) test and 24.60 mg/kg for the pentylenetetrazol (PTZ) test.Formula:C15H11N5OColor and Shape:SolidMolecular weight:277.28Rusfertide
CAS:Rusfertide, a peptide mimetic of natural hepcidin, targets and degrades ferroportin, thereby reducing serum iron and transferrin saturation, which helps regulate red blood cell production. It ameliorates conditions such as polycythemia vera, β-thalassemia, and hereditary hemochromatosis [1] [2].Formula:C114H181N27O28S2Color and Shape:SolidMolecular weight:2441.95Phe-Met-Arg-Phe amide trifluoroacetate
CAS:Phe-met-arg-phe amide trifluoroacetate is an activator of K+ current with an ED50 of 23nm on the fundus nerve.Formula:C33H44F6N8O8SPurity:98%Color and Shape:SolidMolecular weight:826.81Milbemycin A4
CAS:Milbemycin A4, a distinguished member of the macrocyclic lactones family featuring a unique spiroketal group, is derived from the fermentation of the soil bacterium Streptomyces hygroscopicus subsp. aureolacrimosus. It acts by enhancing the opening of glutamate and GABA-gated chloride channels, rendering it effective as both a nematocide and insecticide.Formula:C32H46O7Color and Shape:SolidMolecular weight:542.713Mesoridazine free base
CAS:Mesoridazine (thioridazine EP impurity B) is a phenothiazine antipsychotic with effects similar to chlorpromazine.Formula:C21H26N2OS2Color and Shape:SolidMolecular weight:386.57TRPV4 antagonist 4
CAS:Potent TRPV4 blocker with 22.65 nM IC50; inhibits current and aids acute lung injury.
Formula:C28H32Cl2N6OColor and Shape:SolidMolecular weight:539.50Volixibat
CAS:Volixibat, a selective inhibitor of the bile acid transporter, may treat non-alcoholic steatohepatitis.Formula:C38H51N3O12S2Purity:98%Color and Shape:SolidMolecular weight:805.95CW2158
CW2158 (Compound 13) is a modulator of exportin1 (XPO1). It disrupts chromatin binding and inhibits the activation of NFAT transcription factors and T cells.Formula:C14H8F4N4O2Molecular weight:340.05834BKCa activator-1
BKCa activator-1 (Compound 51b) is an orally active activator of BKCa calcium-activated potassium channels with an EC50 of 2.82 μM. It promotes K+ efflux, leading to cell membrane hyperpolarization and inhibition of smooth muscle contraction. In a spontaneous hypertensive rat (SHR) model, it alleviates urinary incontinence and exhibits antitussive effects in a guinea pig cough model.Formula:C22H23F7N2O3Color and Shape:SolidMolecular weight:496.418
