Potassium Channel
Potassium channels are a diverse group of membrane proteins that facilitate the flow of potassium ions (K+) across the cell membrane. These channels play a crucial role in maintaining the resting membrane potential, regulating cell volume, and controlling the excitability of neurons and muscle cells. Potassium channels are involved in various physiological processes, including cardiac rhythm regulation, insulin secretion, and neurotransmitter release. Dysregulation of potassium channels is linked to conditions such as arrhythmias, epilepsy, and hypertension. At CymitQuimica, we offer a wide range of potassium channel modulators to support your research in electrophysiology, cardiovascular health, and neurobiology.
Found 304 products of "Potassium Channel"
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Tertiapin-RQ
Tertiapin-RQ, an inward rectifier potassium (K+) channel-blocking peptide, exhibits antidepressant effects [1].Formula:C106H175N37O25S4Purity:98%Color and Shape:SolidMolecular weight:2496.02Jingzhaotoxin-XII TFA
Jingzhaotoxin-XII (JzTx-XII) TFA is a specific inhibitor of the Kv4.1 channel, exhibiting an IC50 of 0.363 μM. It interacts with the channel by altering gating behavior.Color and Shape:Odour Solid6-FAM-AEEAC-SHK TFA
6-FAM-AEEAC-SHK TFA, a peptide neurotoxin derived from Stichodactyla helianthus and conjugated with a fluorescent marker, selectively blocks voltage-gated potassium channels (kv1.1 and kv1.2). By prolonging action potentials, it interferes with neural signal conduction, making it valuable in neuroscience research.Formula:C196H295N55O57S7·xCHF3O2Color and Shape:SolidMolecular weight:4558.23 (free acid)Apamin acetate
Apamin acetate: Selective Ca2+-activated K+ channel blocker, 18-amino acid bee venom peptide, promotes synapse repair, anti-inflammatory.Purity:96.97%Color and Shape:SolidTertiapin-Q acetate
Tertiapin-Q acetate is a bee toxin derivative that inhibits BK-type K(+) channels in a concentration-dependent manner.Formula:C108H179N35O26S4Purity:96.44%Color and Shape:SolidMolecular weight:2512.06BmP02
BmP02, a compound isolated from Chinese scorpion (Buthus martensi Karsch) venom, acts as a selective Kv1.3 channel blocker and a highly-selective Kv4.2Formula:C115H182N36O41S7Purity:98%Color and Shape:SolidMolecular weight:2949.35δ-Dendrotoxin
CAS:δ-Dendrotoxin is a potassium (K+) channel blocker derived from black mamba snake venom and is utilized in neurological disease research [1].Formula:C296H452N82O76S6Purity:98%Color and Shape:SolidMolecular weight:6567.65Noxiustoxin
CAS:Noxiustoxin, a toxin extracted from the venom of the Mexican scorpion Centruroides noxius, inhibits both the voltage-dependent potassium channel (Kv1.3, IC50 =Formula:C174H286N52O54S7Purity:98%Color and Shape:SolidMolecular weight:4195Ssm spooky toxin
Ssm Spooky Toxin, derived from Scolopendra mutilans, exhibits potent lethality affecting both hematological and respiratory systems primarily through theFormula:C270H413N69O79S4Purity:98%Color and Shape:SolidMolecular weight:6017.84Spinoxin
CAS:Spinoxin, a 34-residue peptide neurotoxin extracted from the venom of Heterometrus spinifer, is characterized by four disulfide bridges.Formula:C147H236N48O46S9Purity:98%Color and Shape:SolidMolecular weight:3700.33Jingzhaotoxin-X
Jingzhaotoxin-X (JZTX-X) selectively inhibits Kv4.2 and Kv4.3 potassium channels, resulting in prolonged mechanical hyperalgesia [1].Formula:C164H242N46O41S6Purity:98%Color and Shape:SolidMolecular weight:3706.35ShK toxin
CAS:ShK toxin, isolated from the Caribbean sea anemone (Stichodactyla helianthus), is an inhibitor of the voltage-dependent potassium channel (Kv1.3 channel).Formula:C169H274N54O48S7Purity:98%Color and Shape:SolidMolecular weight:4054.8Stromatoxin 1
CAS:Stromatoxin 1, a peptide isolated from tarantulas, acts as an inhibitor of various potassium channels, including K(V)2.1, K(V)2.2, K(V)4.2, and K(V)2.1/9.3.Formula:C156H237N49O48S7Purity:98%Color and Shape:SolidMolecular weight:3791.31HsTX1
CAS:HsTX1, a 34-residue, C-terminally amidated peptide isolated from the scorpion Heterometrus spinnifer, features four disulfide bridges and acts as a potassiumFormula:C149H246N54O46S9Purity:98%Color and Shape:SolidMolecular weight:3818.47Hongotoxin-1
Hongotoxin-1, a chemical compound isolated from the venom of Centruroides limbatus, functions as a potassium channel inhibitor.Formula:C181H299N53O49S7Purity:98%Color and Shape:SolidMolecular weight:4226.13AmmTX3 TFA
AmmTX3 TFA, a peptide toxin derived from Androctonus mauretanicus scorpion venom, functions as a selective blocker of the K_v4 channel.Formula:C158H262N50O48S6·xC2HF3O2Purity:98%Color and Shape:SolidMolecular weight:3822.47 (free acid)Vm24-toxin
CAS:Vm24-toxin, a peptide toxin isolated from the Mexican scorpion Vaejovis mexicanus smithi, serves as an inhibitor of the Kv1.3 potassium channel [1].Formula:C157H253N51O45S9Purity:98%Color and Shape:SolidMolecular weight:3863.59Tamapin
Tamapin, a venom peptide isolated from the Indian red scorpion (Mesobuthus tamulus) [1], selectively targets and blocks small-conductance Ca(2+)-activated KFormula:C146H238N44O41S6Purity:98%Color and Shape:SolidMolecular weight:3458.11Aam-KTX
Aam-KTX, a toxic peptide sourced from Mesobuthus eupeus scorpion venom, acts as a selective K_v channel inhibitor, exhibiting IC_50 values of 1.1 nM for K_v1.3Formula:C174H288N58O48S7Purity:98%Color and Shape:SolidMolecular weight:4184.96Tamapin TFA
Tamapin TFA, a venom peptide isolated from the Indian red scorpion (Mesobuthus tamulus) [1], selectively targets and blocks small conductance Ca(2+)-activated KFormula:C146H238N44O41S6·xC2HF3O2Purity:98%Color and Shape:SolidMolecular weight:3458.11 (free base)Iberiotoxin TFA
Iberiotoxin (TFA) is a selective inhibitor of high conductance Ca2+-activated K+ channels, exhibiting a dissociation constant (Kd) of approximately 1 nM, yet itFormula:C179H274N50O55S7·xC2HF3O2Purity:98%Color and Shape:SolidMolecular weight:4230.85 (free base)Pandinotoxin Kα
CAS:Pandinotoxin Kα, a chemical compound extracted from the emperor scorpion (Pandinus imperator) venom, functions as an inhibitor of the A-type potassium channel [Formula:C169H267N53O48S7Purity:98%Color and Shape:SolidMolecular weight:4033.71KTX-Sp2
KTX-Sp2, a potassium channel toxin, effectively blocks exogenous voltage-gated potassium channels Kv1.1, Kv1.2, and Kv1.3, as well inhibits the endogenous Kv1.3Formula:C155H244N58O49S7Purity:98%Color and Shape:SolidMolecular weight:3928.41Dendrotoxin-I
CAS:Dendrotoxin-I, a neurotoxin from Dendroaspis snake venom, potently blocks K⁺ channels, specifically targeting voltage-gated potassium channel subunits KV1.1 andFormula:C312H491N99O83S6Purity:98%Color and Shape:SolidMolecular weight:7149.24Maurotoxin
CAS:Maurotoxin, a 34-residue peptide featuring four disulfide bridges, is extracted from the chactoid scorpion (Scorpio maurus) and known to impede Shaker potassiumFormula:C145H232N46O46S8Purity:98%Color and Shape:SolidMolecular weight:3612.19κM-Conotoxin RIIIJ
κM-Conotoxin RIIIJ (κM-RIIIJ) selectively inhibits Kv1.2 channels, exhibiting an IC50 value of 33 nM [1].Formula:C117H184N32O36S6Purity:98%Color and Shape:SolidMolecular weight:2807.3Slotoxin
Slotoxin, a peptide extracted from the venom of the Centruroides noxius Hoffmann scorpion, inhibits high-conductance calcium-activated potassium channels with aFormula:C177H275N47O50S7Purity:98%Color and Shape:SolidMolecular weight:4085.82Phrixotoxin 2
CAS:Phrixotoxin 2 selectively blocks the KV 4.2 and KV 4.3 channels, demonstrating high specificity in its interaction with these voltage-gated ion channels [1].Formula:C169H259N49O43S8Purity:98%Color and Shape:SolidMolecular weight:3921.69Aa1 toxin
Aa1 toxin, sourced from Androctonus australis Garzoni venom, is a neurotoxic peptide that specifically blocks potassium channels and has applications inFormula:C156H260N54O49S6Purity:98%Color and Shape:SolidMolecular weight:3868.46Potassium Channel Targeted Library
A unique collection of xnum potassium channel blockers and agonists for high throughput and high content screening;Color and Shape:Odour SolidRef: TM-L7300
1mgTo inquire30μL*10mM (DMSO)To inquire50μL*10mM (DMSO)To inquire100μL*10mM (DMSO)To inquire250μL*10mM (DMSO)To inquireIon Channel Targeted Library
A unique collection of 931 compounds targeting ion channels for research in ion channels-related diseases and ion channel drug discovery;
Color and Shape:Odour SolidADWX 1 TFA
ADWX 1 TFA is a novel peptide that potently targets and inhibits the Kv1.3 channel, with an IC50 of 1.89 pM. It specifically suppresses the activity of the Kv1.3 channel, in addition to inhibiting initial calcium signaling and NF-κB activation. This compound has been shown to ameliorate symptoms in rats with experimental autoimmune encephalomyelitis (EAE). ADWX 1 TFA is utilized in research focused on T-cell-mediated autoimmune diseases.Formula:C169H281N57O46S7·xC2HF3O2Color and Shape:SolidMolecular weight:4071.85 (free base)Cesium chloride
CAS:Cesium chloride (CsCl) is considered to be the most toxic of the alkali chlorides, inhibiting fungal growth.Formula:ClCsPurity:98%Color and Shape:White Solid CrystallineMolecular weight:168.36Myomodulin
CAS:Myomodulin is a neuropeptide present in molluscs, insects, and gastropods.Myomodulin is present in two identified aplysia neurons that contain myomodulin A theFormula:C36H67N11O8S2Purity:98%Color and Shape:SolidMolecular weight:846.12Mesoridazine Besylate
CAS:Mesoridazine Besylate (Serentil), a piperidine antipsychotic and phenothiazine, treats schizophrenia; it's a thioridazine metabolite.Formula:C27H32N2O4S3Purity:98.87%Color and Shape:SolidMolecular weight:544.75KNa1.1-IN-2
CAS:KNa1.1-IN-2 (Compound Z05) is a selective KNa1.1 channel inhibitor capable of penetrating the blood-brain barrier, and exhibits significant efficacy on hERG channels. It binds to KNa1.1 channels, effectively blocking channel activity caused by Gain-of-function (GOF) mutations, thus intervening in KCNT1-related seizures. Additionally, it inhibits the GOF mutant Y796H, making KNa1.1-IN-2 a promising candidate for research into KCNT1-associated epilepsy disorders.Formula:C24H27NOColor and Shape:SolidMolecular weight:345.48KV1.3-IN-1
KV1.3-IN-1 (Compound trans-18), a selective KV1.3 channel inhibitor with IC50 values of 230 nM in Ltk cells and 26.12 nM in PHA-activated T-lymphocytes,Formula:C23H30N2O4SPurity:98%Color and Shape:SolidMolecular weight:430.56Dendrotoxin K TFA
Dendrotoxin K TFA, a Kv1.1 channel blocker, modulates glutamate release in CA3 neurons by time-dependently regulating the presynaptic spike waveform [1].Formula:C294H462N84O75S6·XC2HF3OC2Purity:98%Color and Shape:SolidMolecular weight:6559.66 (free base)Flecainide
CAS:Flecainide is an orally administered antiarrhythmic agent acting as a sodium channel blocker and IKr inhibitor,PSVT.Formula:C17H20F6N2O3Purity:99.896%Color and Shape:SolidMolecular weight:414.34Ref: TM-T21391
5mg46.00€10mg66.00€25mg111.00€50mg177.00€100mg268.00€200mg335.00€1mL*10mM (DMSO)49.00€Nateglinide D5
CAS:Nateglinide D5 is a deuterium labeled Nateglinide.Formula:C19H27NO3Purity:98%Color and Shape:SolidMolecular weight:322.45Cromakalim
CAS:Cromakalim (BRL 34915) is an ATP-dependent K(+) channel opener, a smooth muscle relaxant with antiepileptic activity.Formula:C16H18N2O3Purity:99.39%Color and Shape:SolidMolecular weight:286.33KCNQ1 activator-1
CAS:N-[4-(4-Methoxyphenyl)-2-thiazolyl]-2-piperidinecarboxamide is a potent KCNQ1 activator for LQTS research.Formula:C22H23N3O4S2Purity:99.71%Color and Shape:SolidMolecular weight:457.57Ref: TM-T9778
1mg40.00€5mg89.00€10mg130.00€25mg219.00€50mg324.00€100mg462.00€200mg655.00€1mL*10mM (DMSO)96.00€Clamikalant sodium
CAS:Clamikalant sodium (HMR 1098) is an ATP-dependent potassium channel (KATP) cardiac-selective blocker, used in the study of arrhythmias.Formula:C19H21ClN3NaO5S2Purity:99.95%Color and Shape:SolidMolecular weight:493.96Ref: TM-T63330
1mg48.00€5mg90.00€10mg172.00€25mg346.00€50mg546.00€100mg855.00€200mg1,170.00€1mL*10mM (DMSO)99.00€Endoxifen Z-isomer hydrochloride
CAS:Endoxifen Z-isomer hydrochloride (Endoxifen HCl) is the active metabolite of Tamoxifen, which is an effective and selective estrogen receptor antagonist.Formula:C25H28ClNO2Color and Shape:SolidMolecular weight:409.95Neosolaniol
CAS:Neosolaniol, a type A trichothecene mycotoxin produced by Fusarium species, strongly induces an anorectic (loss of appetite) response.Formula:C19H26O8Purity:98%Color and Shape:SolidMolecular weight:382.4QO-58
CAS:QO-58 is a novel Kv7 activator (opener) that activates neuronal Kv7/KCNQ/M channels, danti-nociceptive effects on inflammatory painFormula:C18H8Cl2F4N4OPurity:99.17%Color and Shape:SolidMolecular weight:443.18Enflurane
CAS:Enflurane (Efrane), a volatile anaesthetic, inhibits Ca2+-activated K+ channels and is used to gauge anesthesia levels in gas chromatography.Formula:C3H2ClF5OPurity:99.64%Color and Shape:Clear Colorless Liquid Ordinary Temperature And Pressure Bp 56 8°C Density 1 50 G Cm-3 At Room Temperature Used As AnMolecular weight:184.49Rimtuzalcap
CAS:Rimtuzalcap (CAD-1883), a selective modulator for SK channels, may treat movement disorders like SCA and ET.Formula:C18H24F2N6OPurity:99.64%Color and Shape:SolidMolecular weight:378.42Ref: TM-T9522
1mg34.00€5mg73.00€10mg105.00€25mg205.00€50mg304.00€100mg429.00€200mg600.00€1mL*10mM (DMSO)33.00€SCH-23390 hydrochloride
CAS:SCH-23390 hydrochloride (R-(+)-SCH23390 hydrochloride) is an effective dopamine receptor antagonist, and for the D1(Ki=0.2 nM) and D5(Ki=0.3 nM).Formula:C17H19Cl2NOPurity:98% - 99.83%Color and Shape:SolidMolecular weight:324.24Ref: TM-T4369
1mg39.00€2mg50.00€5mg78.00€10mg97.00€25mg195.00€50mg369.00€100mg550.00€1mL*10mM (DMSO)78.00€20(S)-Ginsenoside Rg3
CAS:20(S)-Ginsenoside Rg3 (Rg3) possess an ability to inhibit the lung metastasis of tumor cells via inhibition of the adhesion and invasion of tumor cells.Formula:C42H72O13Purity:98.11% - 99.93%Color and Shape:SolidMolecular weight:785.01Tetrandrine
CAS:Tetrandrine (Sinomenine A) is a naturally occurring biphenylisoquinoline alkaloid, a calcium channel inhibitor. Cost-effective and quality-assured.Formula:C38H42N2O6Purity:99.61% - 99.94%Color and Shape:White SolidMolecular weight:622.75NS 11021
CAS:NS 11021 (NS11021) , a novel opener of large-conductance Ca(2+)-activated K(+) channelsFormula:C16H9BrF6N6SPurity:97.26%Color and Shape:SolidMolecular weight:511.24Ref: TM-T4294
1mg42.00€5mg88.00€10mg128.00€25mg263.00€50mg447.00€100mg760.00€200mg1,018.00€1mL*10mM (DMSO)89.00€Tetraethylammonium bromide
CAS:Tetraethylammonium bromide (TEA bromide) can selectively block potassium channels.
Formula:C8H20BrNPurity:98%Color and Shape:White SolidMolecular weight:210.16Tetraethylammonium chloride
CAS:Tetraethylammonium chloride is a quaternary ammonium compound.Formula:C8H20ClNPurity:≥95%Color and Shape:White Solid Solid Particulate/PowderMolecular weight:165.7ML133 hydrochloride
CAS:ML133 hydrochloride (ML133 HCl) is a selective potassium channel inhibitor for Kir2.1, has no effect on Kir1.1 and weak activity for Kir4.1 and Kir7.1.Formula:C19H19NO·HClPurity:99.48%Color and Shape:SolidMolecular weight:313.82Ref: TM-T6592
5mg48.00€10mg63.00€25mg101.00€50mg161.00€100mg259.00€200mg335.00€500mg567.00€1mL*10mM (DMSO)50.00€KCNQ2/3 activator-1
CAS:KCNQ2/3 activator-1 is a Kv7.2/Kv7.3 (KCNQ2/3) potassium channel activator.Formula:C23H29FN2OPurity:99.16% - 99.47%Color and Shape:SolidMolecular weight:368.49Ref: TM-T9400
2mg38.00€5mg58.00€10mg89.00€25mg144.00€50mg224.00€100mg353.00€500mg888.00€1mL*10mM (DMSO)64.00€RY785
CAS:RY785 is a potent and selective inhibitor of voltage-gated potassium channel such as KV2.2 (IC50 = 50 nM). RY785 may be used in pain relief studies.Formula:C21H20N4O2SPurity:99.78%Color and Shape:SolidMolecular weight:392.47Ref: TM-T12786
1mg49.00€5mg137.00€10mg222.00€25mg378.00€50mg530.00€100mg745.00€200mg1,035.00€1mL*10mM (DMSO)118.00€SKF-96365 hydrochloride
CAS:SKF-96365 hydrochloride (SKF96365) , a SOCE inhibitor, exhibits potent anti-neoplastic activity by inducing cell-cycle arrest and apoptosis in colorectal YFormula:C22H27ClN2O3Purity:99.47% - 99.92%Color and Shape:SolidMolecular weight:402.91Ref: TM-T2170
5mg54.00€10mg81.00€25mg131.00€50mg230.00€100mg445.00€200mg680.00€500mg1,054.00€1mL*10mM (DMSO)59.00€CLP290
CAS:CLP290 is an activator of the neuron-specific K+-Cl cotransporter KCC2 and displays potential for the treatment of a wide range of neurological and psychiatricFormula:C19H21FN4O3SPurity:99.93% - >99.99%Color and Shape:SolidMolecular weight:404.46Ref: TM-T5444
1mg34.00€5mg73.00€10mg116.00€25mg190.00€50mg286.00€100mg430.00€200mg628.00€1mL*10mM (DMSO)62.00€Oxypeucedanin
CAS:1.Formula:C16H14O5Purity:98.66% - 98.85%Color and Shape:SolidMolecular weight:286.28Guanosine 5'-diphosphate
CAS:Guanosine 5'-diphosphate (GDP) as Potential Iron Mobilizer, Preventing the Hepcidin-Ferroportin Interaction and Modulating the Interleukin-6/Stat-3 Pathway.Formula:C10H15N5O11P2Purity:98.46% - 99.52%Color and Shape:SolidMolecular weight:443.2VU0134992
CAS:VU0134992 is an Kir4.1 blocker with an IC50 value of 0.97 μMFormula:C20H31BrN2O2Purity:99.86%Color and Shape:SolidMolecular weight:411.38XE 991 dihydrochloride
CAS:XE 991 dihydrochloride is a Kv7 (KCNQ) channel blocker.Formula:C26H22Cl2N2OPurity:98.68%Color and Shape:SolidMolecular weight:449.37BMS-191011
CAS:BMS-191011 (BMS-A) is an activator of large-conductance calcium-activated potassium (BKCa) channels ,effective in stroke modelsFormula:C16H10ClF3N2O3Purity:97.43%Color and Shape:SolidMolecular weight:370.71Guanosine 5'-diphosphate disodium salt
CAS:5'-GDP-Na2: a nucleoside diphosphate, iron mobilizer, blocks hepcidin-ferroportin, affects IL-6/stat-3.
Formula:C10H13N5Na2O11P2Purity:99.40%Color and Shape:White PowderMolecular weight:487.16ML 297
CAS:ML 297 is a selective Kir3.1/3.2 (GIRK1/2) channel activator (IC50 values are 160, 887 and 914 nM for GIRK1/2, GIRK1/4 and GIRK1/3 respectively).Formula:C17H14F2N4OPurity:97.85%Color and Shape:SolidMolecular weight:328.32NS1643
CAS:NS1643 is a potent human ether-a-go-go related gene (hERG) KV11.1 channel activator with EC50 of 10.5 μM.Formula:C15H10F6N2O3Purity:98.37% - 99.31%Color and Shape:SolidMolecular weight:380.24GAL-021
CAS:GAL-021 an intravenous BKCa-channel blocker.Formula:C11H22N6OPurity:97.71% - 99.66%Color and Shape:SolidMolecular weight:254.33Ref: TM-T3557
1mg34.00€5mg71.00€10mg98.00€25mg177.00€50mg268.00€100mg414.00€500mg888.00€1mL*10mM (DMSO)80.00€Daurisoline
CAS:Daurisoline ((R,R)-Daurisoline) is a hERG inhibitor. Daurisoline is also an autophagy blocker.Formula:C37H42N2O6Purity:98% - 99.96%Color and Shape:Light Yellow PowderMolecular weight:610.74Talatisamine
CAS:Talatisamine and TEA mitigate Aβ oligomer effects on I(K), bolstering cell survival and reducing K(+) loss-induced apoptosis; promising for further study.Formula:C24H39NO5Purity:98.62% - 99.44%Color and Shape:SolidMolecular weight:421.57NS-1619
CAS:NS1619 have cardio-protective effects after ischemia-reperfusion injury.Formula:C15H8F6N2O2Purity:97.66% - 98%Color and Shape:SolidMolecular weight:362.23Quinidine
CAS:Quinidine is a stereoisomer of the antimalarial agent quinine and a class Ia antiarrhythmic agent. for the treatment of abnormal heart rhythms and also malaria.Formula:C20H24N2O2Purity:97.03% - 99.99%Color and Shape:Crystals With 2 5 Mol Water Of Crystallization; Crystals From Dilute Alcohol Physical Description Crystals Or White Powder (Ntp 1992)Molecular weight:324.42Ibutilide Fumarate
CAS:Ibutilide Fumarate is a class III antiarrhythmic, prolonging action potentials by enhancing sodium influx, and can extend QT interval.Formula:(C20H36N2O3S)2·C4H4O4Purity:99.68% - 99.74%Color and Shape:SolidMolecular weight:885.23GW9508
CAS:GW9508(GW 9508) is a potent and selective agonist for FFA1 (GPR40), stimulates insulin secretion in a glucose-sensitive manner.
Formula:C22H21NO3Purity:97.89% - 99.19%Color and Shape:SolidMolecular weight:347.41JNJ 303
CAS:JNJ 303 is a potent blocker of IKs (IC50 : 64 nM).Formula:C21H29ClN2O4SPurity:99.28%Color and Shape:SolidMolecular weight:440.98Ref: TM-T7653
1mg46.00€2mg62.00€5mg94.00€10mg140.00€25mg309.00€50mg447.00€100mg667.00€1mL*10mM (DMSO)96.00€TRAM-34
CAS:TRAM-34 (Triarylmethane-34), an effective and specific inhibitor of the intermediate-conductance Ca2+-activated K+ channel, does not block cytochrome P450.
Formula:C22H17ClN2Purity:99.01% - 99.91%Color and Shape:SolidMolecular weight:344.84ML335
CAS:ML335 is a selective activator of TREK-1 and TREK-2.Formula:C15H14Cl2N2O3SPurity:99.73% - 99.79%Color and Shape:SolidMolecular weight:373.25Ref: TM-T4224
2mg40.00€5mg59.00€10mg89.00€25mg177.00€50mg268.00€100mg401.00€200mg580.00€1mL*10mM (DMSO)59.00€BAPTA-AM
CAS:BAPTA-AM is a calcium chelator that is cell-permeable and selective, blocking hERG, hKv1.3, and hKv1.5 channels (IC50=1.3/1.45/1.23 μM).Formula:C34H40N2O18Purity:98% - 99.47%Color and Shape:White Powder Or Crystalline PowderMolecular weight:764.68NS309
CAS:NS309 activates SK/KCa2, IK/KCa3.1 (0.12-1.2 μM EC50, 10-90 nM EC50), and Kv11.1 channels; doesn't affect BK/KCa1.1; modulates neuronal firing.Formula:C8H4Cl2N2O2Purity:97.55%Color and Shape:SolidMolecular weight:231.04Ref: TM-T4612
5mg54.00€10mg65.00€25mg113.00€50mg205.00€100mg305.00€200mg445.00€500mg712.00€1mL*10mM (DMSO)59.00€ICA 110381
CAS:ICA 110381 is a KCNQ2/Q3 potassium channel opener for the treatment of epilepsyFormula:C12H8Cl2N2OPurity:97.72%Color and Shape:SolidMolecular weight:267.11Flecainide hydrochloride
CAS:Flecainide is a medication used to prevent and treat abnormally fast heart rates. This includes ventricular and supraventricular tachycardias.Formula:C17H21ClF6N2O3Purity:97.79%Color and Shape:SolidMolecular weight:450.81ICA-069673
CAS:ICA-069673 is an activator of KCNQ2/Q3 potassium channel (IC50: 0.69 μM).Formula:C11H6ClF2N3OPurity:99.04% - 99.68%Color and Shape:SolidMolecular weight:269.63TKIM
CAS:TKIM is a TWIK-related potassium channel 1 (TREK-1) inhibitor, binding to the pocket of the intermediate (IM) state of TREK-1.Formula:C18H14ClN3O2SPurity:99.47%Color and Shape:SolidMolecular weight:371.84Ref: TM-T8700
1mg39.00€5mg89.00€10mg124.00€25mg212.00€50mg298.00€100mg399.00€200mg537.00€1mL*10mM (DMSO)96.00€Amifampridine
CAS:Amifampridine blocks nerve potassium channels, extends action potentials, boosts acetylcholine release, and treats rare muscle diseases.Formula:C5H7N3Purity:99.82%Color and Shape:Slightly Beige PowderMolecular weight:109.13APD668
CAS:APD668 is a potent GPR119 agonist with EC50 of 2.7 nM and 33 nM for hGPR119 and ratGPR119, respectively.Formula:C21H24FN5O5SPurity:99.74% - 99.97%Color and Shape:SolidMolecular weight:477.51ML277
CAS:ML277 (CID-53347902) was identified as a potent activator of KCNQ1 channels (EC(50)=260 nM).Formula:C23H25N3O4S2Purity:99.35%Color and Shape:SolidMolecular weight:471.59Quinidine sulfate dihydrate
CAS:Quinidine sulfate dihydrate (Pitayine Sodium) is a potent and selective cytochrome P450db inhibitorFormula:C40H54N4O10SPurity:99.85%Color and Shape:White To Light Yellow Crystal PowdeMolecular weight:782.9Ref: TM-T8125
5mg42.00€10mg52.00€25mg73.00€50mg94.00€100mg142.00€200mg207.00€500mg348.00€1mL*10mM (DMSO)62.00€Cholesterol myristate
CAS:Cholesterol myristate, a natural steroid in Chinese medicine, affects GABAA, nicotinic receptors, and potassium channels.
Formula:C41H72O2Purity:99.65%Color and Shape:SolidMolecular weight:597.01Dofetilide
CAS:Dofetilide (UK 68789), a class III antiarrhythmic sulfonamide, blocks Ikr cardiac channels, prolongs action potential, and treats atrial fibrillation/flutter.Formula:C19H27N3O5S2Purity:97.85% - 99.06%Color and Shape:Off-White Or Yellowish Crystalline PowderMolecular weight:441.56Ref: TM-T6476
2mg34.00€5mg50.00€10mg65.00€25mg108.00€50mg167.00€100mg234.00€200mg348.00€1mL*10mM (DMSO)52.00€Minoxidil sulfate
CAS:Minoxidil sulfate (U-58838) is the active metabolite required to exert the vasodilatory and hair growing effects of minoxidil.Formula:C9H15N5O4SPurity:99.01% - 99.72%Color and Shape:White Crystalline SolidMolecular weight:289.31ASP2905
CAS:ASP-2905 is a potent and selective inhibitor of potassium channel Kv12.2 encoded by the Kcnh3/BEC1 gene.Formula:C20H17FN8Purity:97.29% - 99.78%Color and Shape:SolidMolecular weight:388.4Ref: TM-T9070
1mg34.00€2mg46.00€5mg66.00€10mg90.00€25mg178.00€50mg295.00€100mg485.00€1mL*10mM (DMSO)73.00€AM-92016 hydrochloride
CAS:AM-92016 is a specific blocker of rectifier potassium current.Formula:C19H24Cl2N2O4S·HClPurity:98.68%Color and Shape:SolidMolecular weight:483.84Ref: TM-T5585
2mg34.00€5mg50.00€10mg92.00€25mg156.00€50mg264.00€100mg378.00€200mg537.00€1mL*10mM (DMSO)55.00€AUT1
CAS:AUT1 (AUT-1) is a novel specific modulator of Kv3 channels (EC50: 4.7 and 4.9 uM for Kv3.1b and Kv3.2a).Formula:C18H19N3O4Purity:99.8% - 99.95%Color and Shape:SolidMolecular weight:341.36Ref: TM-T5183
1mg34.00€2mg47.00€5mg71.00€10mg101.00€25mg177.00€50mg264.00€100mg404.00€200mg583.00€1mL*10mM (DMSO)79.00€Iptakalim Hydrochloride
CAS:Iptakalim, a lipophilic para-amino compound, is a novel ATP-sensitive potassium channel (KATP) opener, as well as an α4β2-containing nicotinic acetylcholineFormula:C9H22ClNPurity:98%Color and Shape:SolidMolecular weight:179.731GSK369796 Dihydrochloride
CAS:GSK369796 Dihydrochloride (N-tert-butylisoquine),is an anti-malaria drug candidate.Formula:C20H24Cl3N3OPurity:>99.99%Color and Shape:SolidMolecular weight:428.78Ref: TM-T7195
1mg74.00€2mg96.00€5mg141.00€10mg185.00€25mg353.00€50mg532.00€100mg760.00€1mL*10mM (DMSO)138.00€Sematilide hydrochloride
CAS:Sematilide hydrochloride (CK-1752) is a class III antiarrhythmic. It is a selectively delayed rectifier K+ current (IKr) channel blocker.Formula:C14H24ClN3O3SPurity:99.14%Color and Shape:SolidMolecular weight:349.87Ropivacaine hydrochloride monohydrate
CAS:Ropivacaine hydrochloride monohydrate (LEA-103 HCl) is an anaesthetic agent and blocks impulse conduction through inhibiting sodium ion influx reversibly.Formula:C17H29ClN2O2Purity:99.94% - 99.95%Color and Shape:White SolidMolecular weight:328.882,2,2-Trichloroethanol
CAS:2,2,2-Trichloroethanol is an agonist of the nonclassical K2P channels TREK-1 and TRAAK.Formula:C2H3Cl3OPurity:99.74%Color and Shape:LiquidMolecular weight:149.4PAP-1
CAS:PAP-1 (5-(4-Phenoxybutoxy)psoralen) is a selective, and orally active Kv1.3 blocker (EC50: 2 nM).Formula:C21H18O5Purity:99.35% - 99.75%Color and Shape:White SolidMolecular weight:350.36Ref: TM-TQ0179
2mg63.00€5mg88.00€10mg136.00€25mg291.00€50mg520.00€100mg550.00€200mg785.00€1mL*10mM (DMSO)90.00€Quinine dihydrochloride
CAS:Quinine dihydrochloride (Quinine bimuriate) is a primary alkaloid of various species of Cinchona (Rubiaceae).Formula:C20H26Cl2N2O2Purity:99.79% - 99.97%Color and Shape:White SolidMolecular weight:397.34
