Potassium Channel
Potassium channels are a diverse group of membrane proteins that facilitate the flow of potassium ions (K+) across the cell membrane. These channels play a crucial role in maintaining the resting membrane potential, regulating cell volume, and controlling the excitability of neurons and muscle cells. Potassium channels are involved in various physiological processes, including cardiac rhythm regulation, insulin secretion, and neurotransmitter release. Dysregulation of potassium channels is linked to conditions such as arrhythmias, epilepsy, and hypertension. At CymitQuimica, we offer a wide range of potassium channel modulators to support your research in electrophysiology, cardiovascular health, and neurobiology.
Found 276 products of "Potassium Channel"
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Dendrotoxin K TFA
<p>Dendrotoxin K TFA, a Kv1.1 channel blocker, modulates glutamate release in CA3 neurons by time-dependently regulating the presynaptic spike waveform [1].</p>Formula:C294H462N84O75S6·XC2HF3OC2Purity:98%Color and Shape:SolidMolecular weight:6559.66 (free base)BKCa activator-1
<p>BKCa activator-1 (Compound 51b) is an orally active activator of BKCa calcium-activated potassium channels with an EC50 of 2.82 μM. It promotes K+ efflux, leading to cell membrane hyperpolarization and inhibition of smooth muscle contraction. In a spontaneous hypertensive rat (SHR) model, it alleviates urinary incontinence and exhibits antitussive effects in a guinea pig cough model.</p>Formula:C22H23F7N2O3Color and Shape:SolidMolecular weight:496.418Ebio3
<p>Ebio3 is a selective potassium ion channel (KCNQ2) inhibitor with an IC50 of 1.2 nM. It binds to the KCNQ2 channel via its hydrophobic tail, causing the inward movement of the S6 helix, which results in the closure of the internal gate. The inhibitory effect of Ebio3 is equally effective on pathogenic KCNQ2 mutants, such as R75C and I238L, reducing their outward current by approximately 80%. Ebio3 holds potential for research in neurological disorders like epilepsy.</p>Formula:C19H23F2N3O2Color and Shape:SolidMolecular weight:363.4KNa1.1-IN-2
CAS:<p>KNa1.1-IN-2 (Compound Z05) is a selective KNa1.1 channel inhibitor capable of penetrating the blood-brain barrier, and exhibits significant efficacy on hERG channels. It binds to KNa1.1 channels, effectively blocking channel activity caused by Gain-of-function (GOF) mutations, thus intervening in KCNT1-related seizures. Additionally, it inhibits the GOF mutant Y796H, making KNa1.1-IN-2 a promising candidate for research into KCNT1-associated epilepsy disorders.</p>Formula:C24H27NOColor and Shape:SolidMolecular weight:345.48Vesnarinone HCl
<p>Vesnarinone HCl is an oral PDE3 inhibitor improving heart contractility, affecting calcium and potassium flux. Used in heart failure research.</p>Formula:C22H26ClN3O4Purity:99.17%Color and Shape:SoildMolecular weight:431.91Ebio2
<p>Ebio2 is an effective activator of KCNQ2.</p>Formula:C17H19F2N3O2Color and Shape:SolidMolecular weight:335.349Iberiotoxin
CAS:<p>Selective blocker of the big conductance Ca2+-activated K+ channel.</p>Formula:C179H274N50O55S7Purity:98%Color and Shape:SolidMolecular weight:4230Cromakalim
CAS:<p>Cromakalim (BRL 34915) is an ATP-dependent K(+) channel opener, a smooth muscle relaxant with antiepileptic activity.</p>Formula:C16H18N2O3Purity:99.39%Color and Shape:SolidMolecular weight:286.33Nateglinide D5
CAS:<p>Nateglinide D5 is a deuterium labeled Nateglinide.</p>Formula:C19H27NO3Purity:98%Color and Shape:SolidMolecular weight:322.45QO-58
CAS:<p>QO-58 is a novel Kv7 activator (opener) that activates neuronal Kv7/KCNQ/M channels, danti-nociceptive effects on inflammatory pain</p>Formula:C18H8Cl2F4N4OPurity:99.17%Color and Shape:SolidMolecular weight:443.18Flecainide
CAS:<p>Flecainide is an orally administered antiarrhythmic agent acting as a sodium channel blocker and IKr inhibitor,PSVT.</p>Formula:C17H20F6N2O3Purity:99.896%Color and Shape:SolidMolecular weight:414.34Neosolaniol
CAS:<p>Neosolaniol, a type A trichothecene mycotoxin produced by Fusarium species, strongly induces an anorectic (loss of appetite) response.</p>Formula:C19H26O8Purity:98%Color and Shape:SolidMolecular weight:382.4KCNQ1 activator-1
CAS:<p>N-[4-(4-Methoxyphenyl)-2-thiazolyl]-2-piperidinecarboxamide is a potent KCNQ1 activator for LQTS research.</p>Formula:C22H23N3O4S2Purity:99.71%Color and Shape:SolidMolecular weight:457.57Endoxifen Z-isomer hydrochloride
CAS:<p>Endoxifen Z-isomer hydrochloride (Endoxifen HCl) is the active metabolite of Tamoxifen, which is an effective and selective estrogen receptor antagonist.</p>Formula:C25H28ClNO2Color and Shape:SolidMolecular weight:409.95Clamikalant sodium
CAS:<p>Clamikalant sodium (HMR 1098) is an ATP-dependent potassium channel (KATP) cardiac-selective blocker, used in the study of arrhythmias.</p>Formula:C19H21ClN3NaO5S2Purity:99.95%Color and Shape:SolidMolecular weight:493.96Oxypeucedanin
CAS:<p>1.</p>Formula:C16H14O5Purity:98.66% - 98.85%Color and Shape:SolidMolecular weight:286.28Ibutilide Fumarate
CAS:<p>Ibutilide Fumarate is a class III antiarrhythmic, prolonging action potentials by enhancing sodium influx, and can extend QT interval.</p>Formula:(C20H36N2O3S)2·C4H4O4Purity:99.68% - 99.74%Color and Shape:SolidMolecular weight:885.23Guanosine 5'-diphosphate disodium salt
CAS:<p>5'-GDP-Na2: a nucleoside diphosphate, iron mobilizer, blocks hepcidin-ferroportin, affects IL-6/stat-3.</p>Formula:C10H13N5Na2O11P2Purity:99.40%Color and Shape:White PowderMolecular weight:487.16XE 991 dihydrochloride
CAS:<p>XE 991 dihydrochloride is a Kv7 (KCNQ) channel blocker.</p>Formula:C26H22Cl2N2OPurity:98.68%Color and Shape:SolidMolecular weight:449.37SKA-31
CAS:<p>SKA-31 (Naphtho[1,2-d]thiazol-2-ylamine) is an activator of KCa3.1 and KCa2 channels (EC50s: 260, 2900, 2900 nM for KCa3.1, KCa2.1 and KCa2.2 respectively).</p>Formula:C11H8N2SPurity:99.38%Color and Shape:SolidMolecular weight:200.26Ropivacaine hydrochloride monohydrate
CAS:<p>Ropivacaine hydrochloride monohydrate (LEA-103 HCl) is an anaesthetic agent and blocks impulse conduction through inhibiting sodium ion influx reversibly.</p>Formula:C17H29ClN2O2Purity:99.94% - 99.95%Color and Shape:White SolidMolecular weight:328.88Cholesterol myristate
CAS:<p>Cholesterol myristate, a natural steroid in Chinese medicine, affects GABAA, nicotinic receptors, and potassium channels.</p>Formula:C41H72O2Purity:99.65%Color and Shape:SolidMolecular weight:597.01Quinidine sulfate dihydrate
CAS:<p>Quinidine sulfate dihydrate (Pitayine Sodium) is a potent and selective cytochrome P450db inhibitor</p>Formula:C40H54N4O10SPurity:99.85%Color and Shape:White To Light Yellow Crystal PowdeMolecular weight:782.9ML277
CAS:<p>ML277 (CID-53347902) was identified as a potent activator of KCNQ1 channels (EC(50)=260 nM).</p>Formula:C23H25N3O4S2Purity:99.35%Color and Shape:SolidMolecular weight:471.59APD668
CAS:<p>APD668 is a potent GPR119 agonist with EC50 of 2.7 nM and 33 nM for hGPR119 and ratGPR119, respectively.</p>Formula:C21H24FN5O5SPurity:99.74% - 99.97%Color and Shape:SolidMolecular weight:477.51Amifampridine
CAS:<p>Amifampridine blocks nerve potassium channels, extends action potentials, boosts acetylcholine release, and treats rare muscle diseases.</p>Formula:C5H7N3Purity:99.82%Color and Shape:Slightly Beige PowderMolecular weight:109.13TKIM
CAS:<p>TKIM is a TWIK-related potassium channel 1 (TREK-1) inhibitor, binding to the pocket of the intermediate (IM) state of TREK-1.</p>Formula:C18H14ClN3O2SPurity:99.47%Color and Shape:SolidMolecular weight:371.84ICA-069673
CAS:<p>ICA-069673 is an activator of KCNQ2/Q3 potassium channel (IC50: 0.69 μM).</p>Formula:C11H6ClF2N3OPurity:99.04% - 99.68%Color and Shape:SolidMolecular weight:269.63NS309
CAS:<p>NS309 activates SK/KCa2, IK/KCa3.1 (0.12-1.2 μM EC50, 10-90 nM EC50), and Kv11.1 channels; doesn't affect BK/KCa1.1; modulates neuronal firing.</p>Formula:C8H4Cl2N2O2Purity:97.55%Color and Shape:SolidMolecular weight:231.04BAPTA-AM
CAS:<p>BAPTA-AM is a calcium chelator that is cell-permeable and selective, blocking hERG, hKv1.3, and hKv1.5 channels (IC50=1.3/1.45/1.23 μM).</p>Formula:C34H40N2O18Purity:98% - 99.47%Color and Shape:White Powder Or Crystalline PowderMolecular weight:764.68Quinidine
CAS:<p>Quinidine is a stereoisomer of the antimalarial agent quinine and a class Ia antiarrhythmic agent. for the treatment of abnormal heart rhythms and also malaria.</p>Formula:C20H24N2O2Purity:97.03% - 99.99%Color and Shape:Crystals With 2 5 Mol Water Of Crystallization; Crystals From Dilute Alcohol Physical Description Crystals Or White Powder (Ntp 1992)Molecular weight:324.42Talatisamine
CAS:<p>Talatisamine and TEA mitigate Aβ oligomer effects on I(K), bolstering cell survival and reducing K(+) loss-induced apoptosis; promising for further study.</p>Formula:C24H39NO5Purity:98.62% - 99.44%Color and Shape:SolidMolecular weight:421.57VU0134992
CAS:<p>VU0134992 is an Kir4.1 blocker with an IC50 value of 0.97 μM</p>Formula:C20H31BrN2O2Purity:99.86%Color and Shape:SolidMolecular weight:411.38Endoxifen (Z-isomer)
CAS:<p>Endoxifen Z-isomer (EDX) is a key active metabolite of tamoxifen with higher affinity and specificity to estrogen receptors that inhibits aromatase activity.</p>Formula:C25H27NO2Purity:99.19% - 99.81%Color and Shape:SolidMolecular weight:373.49Paederosidic acid methyl ester
CAS:<p>Paederosidic acid methyl ester has antinociception, is possibly related to the pathway of NO-cGMP-ATP sensitive K(+) channels.</p>Formula:C19H26O12SPurity:99.67% - 99.91%Color and Shape:SolidMolecular weight:478.4720(S)-Ginsenoside Rg3
CAS:<p>20(S)-Ginsenoside Rg3 (Rg3) possess an ability to inhibit the lung metastasis of tumor cells via inhibition of the adhesion and invasion of tumor cells.</p>Formula:C42H72O13Purity:98.11% - 99.93%Color and Shape:SolidMolecular weight:785.01KCNQ2/3 activator-1
CAS:<p>KCNQ2/3 activator-1 is a Kv7.2/Kv7.3 (KCNQ2/3) potassium channel activator.</p>Formula:C23H29FN2OPurity:99.16% - 99.47%Color and Shape:SolidMolecular weight:368.492,2,2-Trichloroethanol
CAS:<p>2,2,2-Trichloroethanol is an agonist of the nonclassical K2P channels TREK-1 and TRAAK.</p>Formula:C2H3Cl3OPurity:99.74%Color and Shape:LiquidMolecular weight:149.4Yoda 1
CAS:<p>Yoda 1 is an agonist of the Piezo1 channel that agonizes human- and mouse-derived Piezo1. Yoda 1 is also an inhibitor of GlyT2. Cost-effective, quality assurance.</p>Formula:C13H8Cl2N4S2Purity:98% - 99.98%Color and Shape:SolidMolecular weight:355.27Quinine hydrochloride dihydrate
CAS:<p>Quinine hydrochloride dihydrate (Quinine HCl Dihydrate) is a white crystalline K+ channel blocker, used to treat malaria.</p>Formula:C20H24N2O2·HCl·2H2OPurity:99.91%Color and Shape:White To Light Yellow Crystal PowderMolecular weight:396.91Kv2-IN-A1
CAS:<p>Kv2-IN-A1 is an inhibitor of Kv2.1 and Kv2.2.</p>Formula:C20H17ClN4OSPurity:98.83%Color and Shape:SolidMolecular weight:396.89Almitrine mesylate
CAS:<p>Almitrine mesylate targets Ca2+-dependent K+ channels in rat cells, used for chronic lung hypoxemia.</p>Formula:C28H37F2N7O6S2Purity:99.96%Color and Shape:CoaMolecular weight:669.76Azimilide Dihydrochloride
CAS:<p>Azimilide Dihydrochloride (NE-10064 Dihydrochloride), a novel class III antiarrhythmic agent, blocks both the IKs and IKr with antiarrhythmic activity.</p>Formula:C23H30Cl3N5O3Purity:97.59% - ≥95%Color and Shape:SolidMolecular weight:530.88ML365
CAS:<p>ML365 is a novel selective small molecule inhibitor of TASK1(KCNK3).</p>Formula:C22H20N2O3Purity:98.78%Color and Shape:SolidMolecular weight:360.41VU0071063
CAS:<p>VU0071063 is a Kir6.2/SUR1 activator.</p>Formula:C18H22N4O2Purity:99.33%Color and Shape:SolidMolecular weight:326.39Quinine dihydrochloride
CAS:<p>Quinine dihydrochloride (Quinine bimuriate) is a primary alkaloid of various species of Cinchona (Rubiaceae).</p>Formula:C20H26Cl2N2O2Purity:99.79% - 99.97%Color and Shape:White SolidMolecular weight:397.34Sematilide hydrochloride
CAS:<p>Sematilide hydrochloride (CK-1752) is a class III antiarrhythmic. It is a selectively delayed rectifier K+ current (IKr) channel blocker.</p>Formula:C14H24ClN3O3SPurity:99.14%Color and Shape:SolidMolecular weight:349.87Dofetilide
CAS:<p>Dofetilide (UK 68789), a class III antiarrhythmic sulfonamide, blocks Ikr cardiac channels, prolongs action potential, and treats atrial fibrillation/flutter.</p>Formula:C19H27N3O5S2Purity:97.85% - 99.06%Color and Shape:Off-White Or Yellowish Crystalline PowderMolecular weight:441.56AUT1
CAS:<p>AUT1 (AUT-1) is a novel specific modulator of Kv3 channels (EC50: 4.7 and 4.9 uM for Kv3.1b and Kv3.2a).</p>Formula:C18H19N3O4Purity:99.8% - 99.95%Color and Shape:SolidMolecular weight:341.36Iptakalim Hydrochloride
CAS:<p>Iptakalim, a lipophilic para-amino compound, is a novel ATP-sensitive potassium channel (KATP) opener, as well as an α4β2-containing nicotinic acetylcholine</p>Formula:C9H22ClNPurity:98%Color and Shape:SolidMolecular weight:179.731GSK369796 Dihydrochloride
CAS:<p>GSK369796 Dihydrochloride (N-tert-butylisoquine),is an anti-malaria drug candidate.</p>Formula:C20H24Cl3N3OPurity:>99.99%Color and Shape:SolidMolecular weight:428.78PAP-1
CAS:<p>PAP-1 (5-(4-Phenoxybutoxy)psoralen) is a selective, and orally active Kv1.3 blocker (EC50: 2 nM).</p>Formula:C21H18O5Purity:99.35% - 99.75%Color and Shape:White SolidMolecular weight:350.36Nigericin sodium salt
CAS:<p>Nigericin sodium salt, an antibiotic and NLRP3 activator from S. hygroscopicus, inhibits Golgi and gram-positive bacteria, blocking viral activation.</p>Formula:C40H67NaO11Purity:98.2% - 99.52%Color and Shape:SolidMolecular weight:746.94Atpenin A5
CAS:<p>Atpenin A5 is a potent and highly specific complex II inhibitor (IC50 ~10 nM).</p>Formula:C15H21Cl2NO5Purity:97.33% - 99.91%Color and Shape:SolidMolecular weight:366.24LY 303511 hydrochloride
CAS:<p>LY 303511 hydrochloride is a potent mTOR inhibitor</p>Formula:C19H19ClN2O2Purity:98.47%Color and Shape:SolidMolecular weight:342.82Mitiglinide Calcium
CAS:<p>Mitiglinide Calcium (KAD-1229) is a blood glucose-lowering drugs, stimulating insulin secretion by closing the ATP-sensitive K+ channels in pancreatic beta-</p>Formula:(C19H24NO3)2·CaPurity:99.83%Color and Shape:White Crystal PosderMolecular weight:668.88Flupirtine maleate
CAS:<p>Flupirtine maleate (Katadolon maleate), a centrally acting non-opioid analgesia, is the salt form of Flupirtine. Flupirtine is an NMDA receptor antagonist.</p>Formula:C15H17FN4O2·C4H4O4Purity:99.5% - 99.9%Color and Shape:Off-White Crystalline PowderMolecular weight:420.39Senicapoc
CAS:<p>Senicapoc (ICA-17043) blocks Gardos channel, reduces RBC dehydration, IC50: 11 nM for rubidium flux, 30 nM for dehydration. Used in Sickle Cell therapy.</p>Formula:C20H15F2NOPurity:95.7% - 99.47%Color and Shape:SolidMolecular weight:323.34E-4031 dihydrochloride
CAS:<p>E-4031 is a methanesulfonanilide class III antiarrhythmic agent that prolongs cardiac action potential duration by blocking ERG K+ channels (IC50 = 29 nM)</p>Formula:C21H29Cl2N3O3SPurity:99.31% - 99.87%Color and Shape:SolidMolecular weight:474.44Allocryptopine
CAS:<p>Allocryptopine (Thalictrimine) induces muscle contraction and relaxation in urinary bladder and ileum, respectively.</p>Formula:C21H23NO5Purity:99.41% - ≥95%Color and Shape:SolidMolecular weight:369.41KS176
CAS:<p>KS176: selective BCRP inhibitor, potent against breast cancer drug resistance; ineffective on P-gp, MRP1.</p>Formula:C22H19N3O5Purity:99.61% - 99.61%Color and Shape:SolidMolecular weight:405.45-Hydroxydecanoate sodium
CAS:<p>5-Hydroxydecanoate sodium: KATP channel blocker, IC50 ~30μM; mitochondrial substrate; antioxidant.</p>Formula:C10H19NaO3Purity:99.24% - 99.89%Color and Shape:SolidMolecular weight:210.25VU0810464
CAS:<p>VU0810464 is a non-ureaG protein-gated inwardly-rectifying potassium channels (GIRK, Kir3) activator.</p>Formula:C18H21ClFN3OPurity:99.62%Color and Shape:SolidMolecular weight:349.83Loureirin B
CAS:<p>Loureirin B suppresses fibrosis by modulating MMPs/TIMPs, hindering fibroblast growth, and targeting TGF-β1/Smad2/3 pathway.</p>Formula:C18H20O5Purity:99.33% - 99.86%Color and Shape:SolidMolecular weight:316.35Mitiglinide calcium hydrate
CAS:<p>Mitiglinide calcium hydrate (S-21403 calcium hydrate) is a drug for the treatment of type 2 diabetes.</p>Formula:C38H52CaN2O8Purity:98.97% - 99.96%Color and Shape:White SolidMolecular weight:704.91A2793
CAS:<p>A2793 is a dual inhibitor of TWIK-associated acid-sensitive K+ channel 1 (TASK-1)/TRESK, with an IC50 for mTRESK of 6.8 μM.</p>Formula:C13H12ClNO3Purity:98.54%Color and Shape:SolidMolecular weight:265.69O-Nornuciferine
CAS:<p>O-Nornuciferine reveals distinct in vitro hERG blockages measured in HEK293 cells with the IC50 value of 2.89 uM.</p>Formula:C18H19NO2Purity:99.86%Color and Shape:SolidMolecular weight:281.35ML213
CAS:<p>ML213 (CID-3111211) is a selective activator of Kv7.2 (KCNQ2) and Kv7.4 (KCNQ4) channels, enhances Kv7.2 and Kv7.4 channels with EC50s of 230 and 510 nM,</p>Formula:C17H23NOPurity:>99.99%Color and Shape:SolidMolecular weight:257.37Levcromakalim
CAS:<p>Levcromakalim (BRL 38227) is an activator of the ATP-sensitive K+ channel.</p>Formula:C16H18N2O3Purity:99.74%Color and Shape:SolidMolecular weight:286.33NS 11021
CAS:<p>NS 11021 (NS11021) , a novel opener of large-conductance Ca(2+)-activated K(+) channels</p>Formula:C16H9BrF6N6SPurity:97.26%Color and Shape:SolidMolecular weight:511.24Tetraethylammonium bromide
CAS:<p>Tetraethylammonium bromide (TEA bromide) can selectively block potassium channels.</p>Formula:C8H20BrNPurity:98%Color and Shape:White SolidMolecular weight:210.16ML133 hydrochloride
CAS:<p>ML133 hydrochloride (ML133 HCl) is a selective potassium channel inhibitor for Kir2.1, has no effect on Kir1.1 and weak activity for Kir4.1 and Kir7.1.</p>Formula:C19H19NO·HClPurity:99.48%Color and Shape:SolidMolecular weight:313.82SKF-96365 hydrochloride
CAS:<p>SKF-96365 hydrochloride (SKF96365) , a SOCE inhibitor, exhibits potent anti-neoplastic activity by inducing cell-cycle arrest and apoptosis in colorectal Y</p>Formula:C22H27ClN2O3Purity:99.47% - 99.92%Color and Shape:SolidMolecular weight:402.91Rimtuzalcap
CAS:<p>Rimtuzalcap (CAD-1883), a selective modulator for SK channels, may treat movement disorders like SCA and ET.</p>Formula:C18H24F2N6OPurity:99.64%Color and Shape:SolidMolecular weight:378.42A2764 dihydrochloride
CAS:<p>A2764 dihydrochloride is a highly selective inhibitor of TRESK.</p>Formula:C15H21Cl3N2OPurity:99.05%Color and Shape:SolidMolecular weight:351.7(±)-Naringenin
CAS:<p>(±)-Naringenin (Naringenine) is a natural product.</p>Formula:C15H12O5Purity:98.06%Color and Shape:SolidMolecular weight:272.25Dihydroberberine
CAS:<p>Dihydroberberine has anti-atherosclerotic, anti-inflammatory, hypolipidemic and antitumor activities.</p>Formula:C20H19NO4Purity:93.77%Color and Shape:SolidMolecular weight:337.37Nateglinide
CAS:<p>Nateglinide is an oral drug for type 2 diabetes, stimulating insulin release; may cause rare acute liver injury.</p>Formula:C19H27NO3Purity:99.93% - 99.94%Color and Shape:White Crystalline PowderMolecular weight:317.42Guanosine 5'-diphosphate
CAS:<p>Guanosine 5'-diphosphate (GDP) as Potential Iron Mobilizer, Preventing the Hepcidin-Ferroportin Interaction and Modulating the Interleukin-6/Stat-3 Pathway.</p>Formula:C10H15N5O11P2Purity:98.46% - 99.52%Color and Shape:SolidMolecular weight:443.2ML 297
CAS:<p>ML 297 is a selective Kir3.1/3.2 (GIRK1/2) channel activator (IC50 values are 160, 887 and 914 nM for GIRK1/2, GIRK1/4 and GIRK1/3 respectively).</p>Formula:C17H14F2N4OPurity:97.85%Color and Shape:SolidMolecular weight:328.32NS1643
CAS:<p>NS1643 is a potent human ether-a-go-go related gene (hERG) KV11.1 channel activator with EC50 of 10.5 μM.</p>Formula:C15H10F6N2O3Purity:98.37% - 99.31%Color and Shape:SolidMolecular weight:380.24GAL-021
CAS:<p>GAL-021 an intravenous BKCa-channel blocker.</p>Formula:C11H22N6OPurity:97.71% - 99.66%Color and Shape:SolidMolecular weight:254.33Daurisoline
CAS:<p>Daurisoline ((R,R)-Daurisoline) is a hERG inhibitor. Daurisoline is also an autophagy blocker.</p>Formula:C37H42N2O6Purity:98% - 99.96%Color and Shape:Light Yellow PowderMolecular weight:610.74NS-1619
CAS:<p>NS1619 have cardio-protective effects after ischemia-reperfusion injury.</p>Formula:C15H8F6N2O2Purity:97.66% - 98%Color and Shape:SolidMolecular weight:362.23GW9508
CAS:<p>GW9508(GW 9508) is a potent and selective agonist for FFA1 (GPR40), stimulates insulin secretion in a glucose-sensitive manner.</p>Formula:C22H21NO3Purity:97.89% - 99.19%Color and Shape:SolidMolecular weight:347.41JNJ 303
CAS:<p>JNJ 303 is a potent blocker of IKs (IC50 : 64 nM).</p>Formula:C21H29ClN2O4SPurity:99.28%Color and Shape:SolidMolecular weight:440.98TRAM-34
CAS:<p>TRAM-34 (Triarylmethane-34), an effective and specific inhibitor of the intermediate-conductance Ca2+-activated K+ channel, does not block cytochrome P450.</p>Formula:C22H17ClN2Purity:99.01% - 99.91%Color and Shape:SolidMolecular weight:344.84ML335
CAS:<p>ML335 is a selective activator of TREK-1 and TREK-2.</p>Formula:C15H14Cl2N2O3SPurity:99.73% - 99.79%Color and Shape:SolidMolecular weight:373.25ICA 110381
CAS:<p>ICA 110381 is a KCNQ2/Q3 potassium channel opener for the treatment of epilepsy</p>Formula:C12H8Cl2N2OPurity:97.72%Color and Shape:SolidMolecular weight:267.11Flecainide hydrochloride
CAS:<p>Flecainide is a medication used to prevent and treat abnormally fast heart rates. This includes ventricular and supraventricular tachycardias.</p>Formula:C17H21ClF6N2O3Purity:97.79%Color and Shape:SolidMolecular weight:450.81Minoxidil sulfate
CAS:<p>Minoxidil sulfate (U-58838) is the active metabolite required to exert the vasodilatory and hair growing effects of minoxidil.</p>Formula:C9H15N5O4SPurity:99.01% - 99.72%Color and Shape:White Crystalline SolidMolecular weight:289.31ASP2905
CAS:<p>ASP-2905 is a potent and selective inhibitor of potassium channel Kv12.2 encoded by the Kcnh3/BEC1 gene.</p>Formula:C20H17FN8Purity:97.29%Color and Shape:SolidMolecular weight:388.4AM-92016 hydrochloride
CAS:<p>AM-92016 is a specific blocker of rectifier potassium current.</p>Formula:C19H24Cl2N2O4S·HClPurity:98.68%Color and Shape:SolidMolecular weight:483.84NS6180
CAS:<p>NS6180 is a potent and selective KCa3.1 channel inhibitor(IC50= 9 nM). It prevents T-cell activation and inflammation.</p>Formula:C16H12F3NOSPurity:99.83% - ≥95%Color and Shape:SolidMolecular weight:323.33Tetraethylammonium chloride
CAS:<p>Tetraethylammonium chloride is a quaternary ammonium compound.</p>Formula:C8H20ClNPurity:≥95%Color and Shape:White Solid Solid Particulate/PowderMolecular weight:165.7RY785
CAS:<p>RY785 is a potent and selective inhibitor of voltage-gated potassium channel such as KV2.2 (IC50 = 50 nM). RY785 may be used in pain relief studies.</p>Formula:C21H20N4O2SPurity:99.78%Color and Shape:SolidMolecular weight:392.47Enflurane
CAS:<p>Enflurane (Efrane), a volatile anaesthetic, inhibits Ca2+-activated K+ channels and is used to gauge anesthesia levels in gas chromatography.</p>Formula:C3H2ClF5OPurity:99.64%Color and Shape:Clear Colorless Liquid Ordinary Temperature And Pressure Bp 56 8°C Density 1 50 G Cm-3 At Room Temperature Used As AnMolecular weight:184.49SCH-23390 hydrochloride
CAS:<p>SCH-23390 hydrochloride (R-(+)-SCH23390 hydrochloride) is an effective dopamine receptor antagonist, and for the D1(Ki=0.2 nM) and D5(Ki=0.3 nM).</p>Formula:C17H19Cl2NOPurity:98% - 99.83%Color and Shape:SolidMolecular weight:324.24ICA-105574
CAS:<p>ICA-105574 activates hERG, enhancing peak current and shortening action potential, while modulating activation kinetics.</p>Formula:C19H14N2O4Purity:98.89%Color and Shape:SolidMolecular weight:334.33Branaplam
CAS:<p>Branaplam (LMI 070) is a highly potent, selective and orally active small molecule SMN2 splicing modulator.</p>Formula:C22H27N5O2Purity:98.28% - 99.72%Color and Shape:SolidMolecular weight:393.48
