Potassium Channel
Potassium channels are a diverse group of membrane proteins that facilitate the flow of potassium ions (K+) across the cell membrane. These channels play a crucial role in maintaining the resting membrane potential, regulating cell volume, and controlling the excitability of neurons and muscle cells. Potassium channels are involved in various physiological processes, including cardiac rhythm regulation, insulin secretion, and neurotransmitter release. Dysregulation of potassium channels is linked to conditions such as arrhythmias, epilepsy, and hypertension. At CymitQuimica, we offer a wide range of potassium channel modulators to support your research in electrophysiology, cardiovascular health, and neurobiology.
Found 276 products of "Potassium Channel"
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GSK369796 Dihydrochloride
CAS:<p>GSK369796 Dihydrochloride (N-tert-butylisoquine),is an anti-malaria drug candidate.</p>Formula:C20H24Cl3N3OPurity:>99.99%Color and Shape:SolidMolecular weight:428.78PAP-1
CAS:<p>PAP-1 (5-(4-Phenoxybutoxy)psoralen) is a selective, and orally active Kv1.3 blocker (EC50: 2 nM).</p>Formula:C21H18O5Purity:99.35% - 99.75%Color and Shape:White SolidMolecular weight:350.36Nigericin sodium salt
CAS:<p>Nigericin sodium salt, an antibiotic and NLRP3 activator from S. hygroscopicus, inhibits Golgi and gram-positive bacteria, blocking viral activation.</p>Formula:C40H67NaO11Purity:98.2% - 99.52%Color and Shape:SolidMolecular weight:746.94Atpenin A5
CAS:<p>Atpenin A5 is a potent and highly specific complex II inhibitor (IC50 ~10 nM).</p>Formula:C15H21Cl2NO5Purity:97.33% - 99.91%Color and Shape:SolidMolecular weight:366.24LY 303511 hydrochloride
CAS:<p>LY 303511 hydrochloride is a potent mTOR inhibitor</p>Formula:C19H19ClN2O2Purity:98.47%Color and Shape:SolidMolecular weight:342.82Mitiglinide Calcium
CAS:<p>Mitiglinide Calcium (KAD-1229) is a blood glucose-lowering drugs, stimulating insulin secretion by closing the ATP-sensitive K+ channels in pancreatic beta-</p>Formula:(C19H24NO3)2·CaPurity:99.83%Color and Shape:White Crystal PosderMolecular weight:668.88Flupirtine maleate
CAS:<p>Flupirtine maleate (Katadolon maleate), a centrally acting non-opioid analgesia, is the salt form of Flupirtine. Flupirtine is an NMDA receptor antagonist.</p>Formula:C15H17FN4O2·C4H4O4Purity:99.5% - 99.9%Color and Shape:Off-White Crystalline PowderMolecular weight:420.39Senicapoc
CAS:<p>Senicapoc (ICA-17043) blocks Gardos channel, reduces RBC dehydration, IC50: 11 nM for rubidium flux, 30 nM for dehydration. Used in Sickle Cell therapy.</p>Formula:C20H15F2NOPurity:95.7% - 99.47%Color and Shape:SolidMolecular weight:323.34E-4031 dihydrochloride
CAS:<p>E-4031 is a methanesulfonanilide class III antiarrhythmic agent that prolongs cardiac action potential duration by blocking ERG K+ channels (IC50 = 29 nM)</p>Formula:C21H29Cl2N3O3SPurity:99.31% - 99.87%Color and Shape:SolidMolecular weight:474.44Allocryptopine
CAS:<p>Allocryptopine (Thalictrimine) induces muscle contraction and relaxation in urinary bladder and ileum, respectively.</p>Formula:C21H23NO5Purity:99.41% - ≥95%Color and Shape:SolidMolecular weight:369.41KS176
CAS:<p>KS176: selective BCRP inhibitor, potent against breast cancer drug resistance; ineffective on P-gp, MRP1.</p>Formula:C22H19N3O5Purity:99.61% - 99.61%Color and Shape:SolidMolecular weight:405.45-Hydroxydecanoate sodium
CAS:<p>5-Hydroxydecanoate sodium: KATP channel blocker, IC50 ~30μM; mitochondrial substrate; antioxidant.</p>Formula:C10H19NaO3Purity:99.24% - 99.89%Color and Shape:SolidMolecular weight:210.25VU0810464
CAS:<p>VU0810464 is a non-ureaG protein-gated inwardly-rectifying potassium channels (GIRK, Kir3) activator.</p>Formula:C18H21ClFN3OPurity:99.62%Color and Shape:SolidMolecular weight:349.83Loureirin B
CAS:<p>Loureirin B suppresses fibrosis by modulating MMPs/TIMPs, hindering fibroblast growth, and targeting TGF-β1/Smad2/3 pathway.</p>Formula:C18H20O5Purity:99.33% - 99.86%Color and Shape:SolidMolecular weight:316.35Mitiglinide calcium hydrate
CAS:<p>Mitiglinide calcium hydrate (S-21403 calcium hydrate) is a drug for the treatment of type 2 diabetes.</p>Formula:C38H52CaN2O8Purity:98.97% - 99.96%Color and Shape:White SolidMolecular weight:704.91A2793
CAS:<p>A2793 is a dual inhibitor of TWIK-associated acid-sensitive K+ channel 1 (TASK-1)/TRESK, with an IC50 for mTRESK of 6.8 μM.</p>Formula:C13H12ClNO3Purity:98.54%Color and Shape:SolidMolecular weight:265.69O-Nornuciferine
CAS:<p>O-Nornuciferine reveals distinct in vitro hERG blockages measured in HEK293 cells with the IC50 value of 2.89 uM.</p>Formula:C18H19NO2Purity:99.86%Color and Shape:SolidMolecular weight:281.35ML213
CAS:<p>ML213 (CID-3111211) is a selective activator of Kv7.2 (KCNQ2) and Kv7.4 (KCNQ4) channels, enhances Kv7.2 and Kv7.4 channels with EC50s of 230 and 510 nM,</p>Formula:C17H23NOPurity:>99.99%Color and Shape:SolidMolecular weight:257.37Levcromakalim
CAS:<p>Levcromakalim (BRL 38227) is an activator of the ATP-sensitive K+ channel.</p>Formula:C16H18N2O3Purity:99.74%Color and Shape:SolidMolecular weight:286.33NS 11021
CAS:<p>NS 11021 (NS11021) , a novel opener of large-conductance Ca(2+)-activated K(+) channels</p>Formula:C16H9BrF6N6SPurity:97.26%Color and Shape:SolidMolecular weight:511.24Tetraethylammonium bromide
CAS:<p>Tetraethylammonium bromide (TEA bromide) can selectively block potassium channels.</p>Formula:C8H20BrNPurity:98%Color and Shape:White SolidMolecular weight:210.16ML133 hydrochloride
CAS:<p>ML133 hydrochloride (ML133 HCl) is a selective potassium channel inhibitor for Kir2.1, has no effect on Kir1.1 and weak activity for Kir4.1 and Kir7.1.</p>Formula:C19H19NO·HClPurity:99.48%Color and Shape:SolidMolecular weight:313.82SKF-96365 hydrochloride
CAS:<p>SKF-96365 hydrochloride (SKF96365) , a SOCE inhibitor, exhibits potent anti-neoplastic activity by inducing cell-cycle arrest and apoptosis in colorectal Y</p>Formula:C22H27ClN2O3Purity:99.47% - 99.92%Color and Shape:SolidMolecular weight:402.91Rimtuzalcap
CAS:<p>Rimtuzalcap (CAD-1883), a selective modulator for SK channels, may treat movement disorders like SCA and ET.</p>Formula:C18H24F2N6OPurity:99.64%Color and Shape:SolidMolecular weight:378.42A2764 dihydrochloride
CAS:<p>A2764 dihydrochloride is a highly selective inhibitor of TRESK.</p>Formula:C15H21Cl3N2OPurity:99.05%Color and Shape:SolidMolecular weight:351.7(±)-Naringenin
CAS:<p>(±)-Naringenin (Naringenine) is a natural product.</p>Formula:C15H12O5Purity:98.06%Color and Shape:SolidMolecular weight:272.25Dihydroberberine
CAS:<p>Dihydroberberine has anti-atherosclerotic, anti-inflammatory, hypolipidemic and antitumor activities.</p>Formula:C20H19NO4Purity:93.77%Color and Shape:SolidMolecular weight:337.37Nateglinide
CAS:<p>Nateglinide is an oral drug for type 2 diabetes, stimulating insulin release; may cause rare acute liver injury.</p>Formula:C19H27NO3Purity:99.93% - 99.94%Color and Shape:White Crystalline PowderMolecular weight:317.42Guanosine 5'-diphosphate
CAS:<p>Guanosine 5'-diphosphate (GDP) as Potential Iron Mobilizer, Preventing the Hepcidin-Ferroportin Interaction and Modulating the Interleukin-6/Stat-3 Pathway.</p>Formula:C10H15N5O11P2Purity:98.46% - 99.52%Color and Shape:SolidMolecular weight:443.2ML 297
CAS:<p>ML 297 is a selective Kir3.1/3.2 (GIRK1/2) channel activator (IC50 values are 160, 887 and 914 nM for GIRK1/2, GIRK1/4 and GIRK1/3 respectively).</p>Formula:C17H14F2N4OPurity:97.85%Color and Shape:SolidMolecular weight:328.32NS1643
CAS:<p>NS1643 is a potent human ether-a-go-go related gene (hERG) KV11.1 channel activator with EC50 of 10.5 μM.</p>Formula:C15H10F6N2O3Purity:98.37% - 99.31%Color and Shape:SolidMolecular weight:380.24GAL-021
CAS:<p>GAL-021 an intravenous BKCa-channel blocker.</p>Formula:C11H22N6OPurity:97.71% - 99.66%Color and Shape:SolidMolecular weight:254.33Daurisoline
CAS:<p>Daurisoline ((R,R)-Daurisoline) is a hERG inhibitor. Daurisoline is also an autophagy blocker.</p>Formula:C37H42N2O6Purity:98% - 99.96%Color and Shape:Light Yellow PowderMolecular weight:610.74NS-1619
CAS:<p>NS1619 have cardio-protective effects after ischemia-reperfusion injury.</p>Formula:C15H8F6N2O2Purity:97.66% - 98%Color and Shape:SolidMolecular weight:362.23GW9508
CAS:<p>GW9508(GW 9508) is a potent and selective agonist for FFA1 (GPR40), stimulates insulin secretion in a glucose-sensitive manner.</p>Formula:C22H21NO3Purity:97.89% - 99.19%Color and Shape:SolidMolecular weight:347.41JNJ 303
CAS:<p>JNJ 303 is a potent blocker of IKs (IC50 : 64 nM).</p>Formula:C21H29ClN2O4SPurity:99.28%Color and Shape:SolidMolecular weight:440.98TRAM-34
CAS:<p>TRAM-34 (Triarylmethane-34), an effective and specific inhibitor of the intermediate-conductance Ca2+-activated K+ channel, does not block cytochrome P450.</p>Formula:C22H17ClN2Purity:99.01% - 99.91%Color and Shape:SolidMolecular weight:344.84ML335
CAS:<p>ML335 is a selective activator of TREK-1 and TREK-2.</p>Formula:C15H14Cl2N2O3SPurity:99.73% - 99.79%Color and Shape:SolidMolecular weight:373.25ICA 110381
CAS:<p>ICA 110381 is a KCNQ2/Q3 potassium channel opener for the treatment of epilepsy</p>Formula:C12H8Cl2N2OPurity:97.72%Color and Shape:SolidMolecular weight:267.11Flecainide hydrochloride
CAS:<p>Flecainide is a medication used to prevent and treat abnormally fast heart rates. This includes ventricular and supraventricular tachycardias.</p>Formula:C17H21ClF6N2O3Purity:97.79%Color and Shape:SolidMolecular weight:450.81Minoxidil sulfate
CAS:<p>Minoxidil sulfate (U-58838) is the active metabolite required to exert the vasodilatory and hair growing effects of minoxidil.</p>Formula:C9H15N5O4SPurity:99.01% - 99.72%Color and Shape:White Crystalline SolidMolecular weight:289.31ASP2905
CAS:<p>ASP-2905 is a potent and selective inhibitor of potassium channel Kv12.2 encoded by the Kcnh3/BEC1 gene.</p>Formula:C20H17FN8Purity:97.29%Color and Shape:SolidMolecular weight:388.4AM-92016 hydrochloride
CAS:<p>AM-92016 is a specific blocker of rectifier potassium current.</p>Formula:C19H24Cl2N2O4S·HClPurity:98.68%Color and Shape:SolidMolecular weight:483.84NS6180
CAS:<p>NS6180 is a potent and selective KCa3.1 channel inhibitor(IC50= 9 nM). It prevents T-cell activation and inflammation.</p>Formula:C16H12F3NOSPurity:99.83% - ≥95%Color and Shape:SolidMolecular weight:323.33Tetraethylammonium chloride
CAS:<p>Tetraethylammonium chloride is a quaternary ammonium compound.</p>Formula:C8H20ClNPurity:≥95%Color and Shape:White Solid Solid Particulate/PowderMolecular weight:165.7RY785
CAS:<p>RY785 is a potent and selective inhibitor of voltage-gated potassium channel such as KV2.2 (IC50 = 50 nM). RY785 may be used in pain relief studies.</p>Formula:C21H20N4O2SPurity:99.78%Color and Shape:SolidMolecular weight:392.47Enflurane
CAS:<p>Enflurane (Efrane), a volatile anaesthetic, inhibits Ca2+-activated K+ channels and is used to gauge anesthesia levels in gas chromatography.</p>Formula:C3H2ClF5OPurity:99.64%Color and Shape:Clear Colorless Liquid Ordinary Temperature And Pressure Bp 56 8°C Density 1 50 G Cm-3 At Room Temperature Used As AnMolecular weight:184.49SCH-23390 hydrochloride
CAS:<p>SCH-23390 hydrochloride (R-(+)-SCH23390 hydrochloride) is an effective dopamine receptor antagonist, and for the D1(Ki=0.2 nM) and D5(Ki=0.3 nM).</p>Formula:C17H19Cl2NOPurity:98% - 99.83%Color and Shape:SolidMolecular weight:324.24ICA-105574
CAS:<p>ICA-105574 activates hERG, enhancing peak current and shortening action potential, while modulating activation kinetics.</p>Formula:C19H14N2O4Purity:98.89%Color and Shape:SolidMolecular weight:334.33Branaplam
CAS:<p>Branaplam (LMI 070) is a highly potent, selective and orally active small molecule SMN2 splicing modulator.</p>Formula:C22H27N5O2Purity:98.28% - 99.72%Color and Shape:SolidMolecular weight:393.48
