ATPase

Ciclopirox exerts its action by binding to and chelating trivalent cations, such as Fe3+ and …

Gboxin is an inhibitor of oxidative phosphorylation that targets glioblastoma,inhibits the activity of F0F1 ATP …

Clorsulon is utilized for the treatment of Fasciola hepatica infections in calves and sheep.

Digitoxin is an effective Na+/K+-ATPase inhibitor (EC50 value: 0.78 μM).

Fenbufen is a non-steroidal anti-inflammatory drug used primarily to treat inflammation in osteoarthritis, ankylosing spondylitis, …

Trichlormethiazide is a short-acting, 3-dichloromethyl derivative of hydrochlorothiazide, belonging to the class of thiazide diuretics. …

Ciclopirox Olamine is a broad-spectrum antifungal agent with additional antibacterial and anti-inflammatory activities.

ATP synthase inhibitor 1 is an inhibitor of the c subunit of the F1/FO-ATP synthase …

Isokaempferide shows hepatoprotective, antiproliferative, and anti-inflammatory effects, the anti-inflammatory effects can be explained, at least …

Goniothalamin induces apoptosis in various cancer cell lines and has gastroprotective activity.

Echinatin exerts a protective effect against ischemia/reperfusion (I/R)-induced myocardial injury on hearts, this effect may …

Lupanine has a weak sedative effect on the central nervous system, interaction with specific drugs …

(-)-Denudatin B is derived from Magnolia fargesii. (-)-Denudatin B has nonspecific antiplatelet action at high …

Lasiodiplodin may have potential anti-inflammatory activity, it shows moderate suppression effects on induced NO production. …

Stauntosaponin A and stauntosaponin B show moderate inhibitory activities against Na+/K+-ATPase with IC50 values of …

Encecalin and demethylencecalin are major phytotoxic compounds isolated from Helianthella quinquenervis (Hook) A Gray (Asteraceae), …

SCH28080 inhibits gastric H+/K+-ATPase by K+-competitive binding (IC50: 20 nM in rabbit microsomal membranes).

Sudoterb, also known as LL3858, is an anti-tubercular drug candidate.

PF 3716556, an effective and specific P-CAB (potassium-competitive acid blocker), is utilized for the treatment …

Thevetin B is a cardiac glycoside and an inhibitor of Na+-, K+-dependent adenosinetriphosphatase (Na+,K+-ATPase) from …

Cycloartane-3,24,25-triol has potential for development as an anti-cancer agent against prostate cancer. It reduces the …

Odoroside H has anticancer activities, the cytotoxic effects are induced by the inhibition of the …

5,2',6'-Trihydroxy-6,7,8-trimethoxyflavone (ED 50 =4.5 ug/ml ) shows cytotoxicity against L1210 cell and has inhibiting effects …

(-)-Praeruptorin A has anti-inflammatory, anti-contractile and anti-hyperplasia activities, it exerts distinct relaxant effects on isolated …

Blebbistatin is a selective non-muscle myosin II (NMII) inhibitor. It promotes directional migration of corneal …

3-methyl-1,2-dihydroquinolin-2-one is the first known micromolar inhibitors of the ATAD2 bromodomain.

KM 91104 is a cell permeable inhibitor of V-ATPase. KM91104 specifically targets the interaction between …

BHQ is an effective and selective endoplasmic reticulum Ca2+-ATPase inhibitor.

BRITE 338733 is a novel inhibitor of ATPase. BRITE 338733 inhibits the expression of RecA …

Mitiglinide Calcium is a blood glucose-lowering drugs, stimulating insulin secretion by closing the ATP-sensitive K+ …

Brefeldin A , a Penicillium brefeldianum metabolite, which is a macrocyclic lactone exhibiting a wide …

Rbin-1 is a potent,specific inhibitor of eukaryotic ribosome biogenesis.

Cinobufagin is a selective Na+/K+-ATPase inhibitor. The activity of Cinobufagin is same as ouabain.

Oligomycin A is an inhibitor of ATP synthase, inhibits oxidative phosphorylation and all the ATP-dependent …

Esomeprazole Magnesium is the S-isomer of omeprazole, can reduce gastric acid secretion with selective and …

Deslanoside is a rapidly acting cardiac glycoside used to treat congestive heart failure and supraventricular …

Wilforine is a sesquiterpene pyridine alkaloid; important bioactive compound in T. wilfordii plants, and is …

Diphyllin could be characterized as a new V-ATPase inhibitor in treating gastric cancer and inhibiting …

Lanatoside C is a cardiac glycoside, a type of drug that can be used in …

Revaprazan Hydrochloride is the hydrochloride salt form of a lipophilic, weak base with potassium-competitive acid …

(-)-Blebbistatin is an S enantiomer of blebbistatin. It is a potent and selective myosin II …

Pyridoxal Phosphate is the active form of vitamin B6 and a coenzyme for many pyridoxal …

Paederosidic acid methyl ester has antinociception, is possibly related to the pathway of NO-cGMP-ATP sensitive …

Transdermal Peptide (TD 1 peptide) acetate is a 11-amino acid peptide, binds toNa+/K+-ATPase beta-subunit (ATP1B1), …

Esomeprazole Sodium is the S-isomer of omeprazole with selective and irreversible proton pump inhibitor activity.Esomeprazole …

Rostafuroxin has been used in trials studying the treatment of Essential Hypertension.

Epimagnolin A is a lignan obtained from the flower buds of Magnolia fargesii, which is …

Tegoprazan is a potassium-competitive acid blocker and is a potent, oral active, and highly selective …

FCCP, a potent uncoupler of oxidative phosphorylation in mitochondria, transport protons across cell membranes leading …

Bufalin is an active ingredient and one of the glycosides in the traditional Chinese medicine …

Eniporide is a Na(+)/H(+) exchange inhibitor.

Vonoprazan Fumarate (TAK-438) is a novel P-CAB (potassium-competitive acid blocker) that reversibly inhibits H+/K+, ATPase.

Omecamtiv Mecarbil has been used in trials studying the treatment and basic science of Heart …

7,3',4'-Trihydroxyflavone inhibits osteoclastogenesis via the nuclear factor of activated T cells c1. 7,3',4'-Trihydroxyflavone can markedly …