Sodium Channel
Sodium channels are essential membrane proteins that allow the passage of sodium ions (Na+) across the cell membrane, generating and propagating electrical signals in neurons, muscle cells, and other excitable tissues. These channels are vital for the initiation and conduction of action potentials, making them crucial in processes such as nerve impulse transmission, muscle contraction, and cardiac function. Dysregulation of sodium channels can lead to neurological disorders, arrhythmias, and chronic pain conditions. At CymitQuimica, we provide a variety of sodium channel modulators to support your research in neurobiology, cardiology, and pain management.
Found 273 products for "Sodium Channel".
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Nav1.8-IN-4
CAS:Nav1.8-IN-4 is a potent Nav1.8 channel inhibitor with potential analgesic activity.Nav1.8-IN-4 can be used for pain and neurological related disorders.Formula:C20H14F4N2O3Purity:99.97%Color and Shape:SolidMolecular weight:406.33Ref: TM-T77693
1mg56.00€2mg80.00€5mg118.00€10mg178.00€25mg356.00€50mg580.00€100mg888.00€500mg1,783.00€Tocainide hydrochloride
CAS:Tocainide hydrochloride (2-amino-n-(2,6-dimethylphenyl)propanamide hydrochloride) is a sodium channel blocker.Formula:C11H17ClN2OPurity:97%Color and Shape:SolidMolecular weight:228.72Benzocaine
CAS:Benzocaine is a surface anesthetic that acts by preventing transmission of impulses along nerve fibers and at nerve endings.Formula:C9H11NO2Purity:99.16% - 99.88%Color and Shape:Rhombohedra From Ether DrypowderMolecular weight:165.19Topiramate
CAS:Topiramate (RWJ 17021) is a unique antiseizure medication that is used in the treatment of partial and generalized seizures.Formula:C12H21NO8SPurity:99.79% - 99.92%Color and Shape:SolidMolecular weight:339.36Eleclazine hydrochloride
CAS:Eleclazine hydrochloride (GS 6615 hydrochloride) is a novel inhibitor of late Na+ current (IC50: 0.7 uM).Formula:C21H17ClF3N3O3Purity:99.86%Color and Shape:SolidMolecular weight:451.83Ref: TM-T15207
1mg58.00€5mg110.00€1mL*10mM (DMSO)122.00€10mg166.00€25mg268.00€50mg403.00€100mg532.00€200mg705.00€Lamotrigine
CAS:Lamotrigine (BW430C) is an Anti-epileptic Agent and Mood Stabilizer.Formula:C9H7Cl2N5Purity:99.76% - 99.95%Color and Shape:White SolidMolecular weight:256.09Lidocaine Hydrochloride hydrate
CAS:Lidocaine Hydrochloride hydrate is an amide local anesthetic, has anti-inflammatory property.Formula:C14H22N2O·HCl·H2OPurity:99.95%Color and Shape:SolidMolecular weight:288.82Phenytoin sodium
CAS:Phenytoin sodium (Diphantoine) is an inactive stabilizer for voltage-gated sodium channel .Formula:C15H11N2NaO2Purity:99.88% - 99.92%Color and Shape:SolidMolecular weight:274.25Mexiletine hydrochloride
CAS:Mexiletine hydrochloride is a lidocaine-like antiarrhythmic (Class IB) and anesthetic, stabilizing heartbeats by inhibiting sodium in cardiac cells.Formula:C11H18ClNOPurity:99.88%Color and Shape:SolidMolecular weight:215.72Oxcarbazepine
CAS:Oxcarbazepine (GP 47680), an anti-epileptic, reduces CNS disorganized electrical activity.Formula:C15H12N2O2Purity:98.46%Color and Shape:White SolidMolecular weight:252.27Ref: TM-T0440
5mg34.00€10mg50.00€1mL*10mM (DMSO)55.00€25mg77.00€50mg96.00€100mg132.00€200mg171.00€500mg222.00€Dibucaine
CAS:Dibucaine (Cinchocaine), a local anesthetic of the amide type, is now usually used for surface anesthesia.Formula:C20H29N3O2Purity:99.69% - 99.88%Color and Shape:White SolidMolecular weight:343.46Lidocaine
CAS:Lidocaine, an amide local anesthetic, reduces pain and inflammation by dampening ICAM-1, cytokines, and neutrophil influx.Formula:C14H22N2OPurity:99.88% - >99.99%Color and Shape:White SolidMolecular weight:234.34DSP-2230
CAS:DSP-2230 is a selective blocker of Nav1.7/Nav1.8.Formula:C20H20F3N5O2Purity:97.14%Color and Shape:SolidMolecular weight:419.4Ref: TM-T15174
1mg34.00€5mg66.00€1mL*10mM (DMSO)73.00€10mg99.00€25mg205.00€50mg334.00€100mg537.00€200mg762.00€Tocainide
CAS:Tocainide is a blocker of the sodium channel and used for the treatment of tinnitus.Formula:C11H16N2OPurity:99.84%Color and Shape:SolidMolecular weight:192.26Vinpocetine
CAS:Vinpocetine (RGH-4405) is a selective inhibitor of cyclic GMP phosphodiesterase (PDE).Formula:C22H26N2O2Purity:99.85% - 99.98%Color and Shape:White SolidMolecular weight:350.45Phenazopyridine hydrochloride
CAS:Phenazopyridine HCl, an oral urinary analgesic, may cause nausea, anemia, and liver/kidney toxicity. Possibly carcinogenic.Formula:C11H12ClN5Purity:99.27%Color and Shape:SolidMolecular weight:249.7Propafenone
CAS:Propafenone: a drug for ventricular arrhythmias with mild beta-blocker activity, prolongs refractory period, and reduces heart automaticity.Formula:C21H27NO3Purity:99.02%Color and Shape:SolidMolecular weight:341.44Ranolazine dihydrochloride
CAS:Ranolazine 2HCl, an antianginal, treats arrhythmia by inhibiting sodium current without changing blood pressure or heart rate.Formula:C24H35Cl2N3O4Purity:99.30% - >99.99%Color and Shape:White Crystalline PowderMolecular weight:500.46Meticrane
CAS:Meticrane (Arresten) is a sulphonamide-derivative with thiazide-like diuretic activity.Formula:C10H13NO4S2Purity:99.16%Color and Shape:SolidMolecular weight:275.34Amitriptyline hydrochloride
CAS:Amitriptyline hydrochloride (Annoyltin) is the hydrochloride salt of the tricyclic dibenzocycloheptadiene amitriptyline with antidepressant and antinociceptiveFormula:C20H24ClNPurity:99.39% - 99.94%Color and Shape:SolidMolecular weight:313.86Mebeverine hydrochloride
CAS:Mebeverine hydrochloride (Colofac Hydrochloride), a β-phenylethylamine derivative, is a potent α1 repector inhibitor, relaxing the muscles in and around the gutFormula:C25H35NO5Purity:99.81% - 99.81%Color and Shape:SolidMolecular weight:429.55Disopyramide
CAS:Disopyramide, or Triombrin, a class I anti-arrhythmic with membrane-stabilizing effects, has heart depressant, anticholinergic, and anesthetic properties.Formula:C21H29N3OPurity:99.62%Color and Shape:White SolidMolecular weight:339.47E 0747 FA
E 0747 FA is an antiarrhythmic compound that inhibits the voltage of action potential Vmax in Purkinje fibers of porcine heart.E 0747 FA inhibits Na channels in cardiac cells.Formula:C22H30ClN3O6Purity:99.96%Color and Shape:White SolidMolecular weight:467.94Amiloride hydrochloride
CAS:Amiloride hydrochloride (Amiloride HCl) 是上皮钠通道和尿激酶型纤溶酶原激活物受体的抑制剂，也是 polycystin-2通道阻断剂。Formula:C6H9Cl2N7OPurity:99.72% - 99.95%Color and Shape:Physical Description Crystalline Solid Or Very Light Yellow Powder (Ntp 1992)Molecular weight:266.09Butamben
CAS:Butamben (Butyl 4-aminobenzoate) is a long-duration local anesthetic used for the treatment of chronic pain.Formula:C11H15NO2Purity:99.43%Color and Shape:SolidMolecular weight:193.24Methocarbamol
CAS:Methocarbamol (AHR 85) is a centrally acting muscle relaxant whose mode of action has not been established.Formula:C11H15NO5Purity:99.96%Color and Shape:White SolidMolecular weight:241.24Primidone
CAS:Primidone (NCI-C56360) is a potent anticonvulsant agent.Formula:C12H14N2O2Purity:99.91%Color and Shape:SolidMolecular weight:218.25Brompheniramine maleate
CAS:Brompheniramine maleate (Dimotane) is an antagonist against histamine H1 receptors.Formula:C16H19BrN2·C4H4O4Purity:99.80%Color and Shape:SolidMolecular weight:435.31QX-314 chloride
CAS:QX-314 chloride is a membrane-impermeable permanently charged blocker of sodium channel.Formula:C16H27ClN2OPurity:99.73%Color and Shape:SolidMolecular weight:298.85Articaine hydrochloride
CAS:Articaine hydrochloride (Hoe-045) is a thiophene-containing local anesthetic pharmacologically similar to MEPIVACAINE.Formula:C13H21ClN2O3SPurity:99.76%Color and Shape:SolidMolecular weight:320.84Phenytoin
CAS:Phenytoin: a non-sedative hydantoin, antiepileptic with anticonvulsant effects, stabilizes neurons, prevents seizure spread, and relaxes muscles.Formula:C15H12N2O2Purity:99.95%Color and Shape:White SolidMolecular weight:252.27Nefopam hydrochloride
CAS:Nefopam hydrochloride (Nefopam HCl) is the hydrochloride salt form of nefopam, a centrally-acting, non-opioid benzoxazocine with analgesic activity.Formula:C17H20ClNOPurity:99.32% - 99.85%Color and Shape:White SolidMolecular weight:289.8Flunarizine dihydrochloride
CAS:Flunarizine dihydrochloride: a calcium blocker also targeting calmodulin and histamine H1, used for migraine, vertigo, vascular disease, and epilepsy aid.Formula:C26H28Cl2F2N2Purity:99.53% - 99.99%Color and Shape:White SolidMolecular weight:477.42Ropivacaine
CAS:Ropivacaine (LEA-103 HCl) is a local anaesthetic drug belonging to the amino amide group.Formula:C17H26N2OPurity:97.75% - >99.99%Color and Shape:SolidMolecular weight:274.40PF-04885614
CAS:PF-04885614 is a potent inhibitor of NaV1.8, has potential for neurological and neurodevelopmental diseases treatment.Formula:C13H14F3N3OPurity:98.02%Color and Shape:SolidMolecular weight:285.27Ref: TM-T12421
2mg39.00€5mg60.00€1mL*10mM (DMSO)60.00€10mg96.00€25mg166.00€50mg299.00€100mg424.00€200mg595.00€Diphenidol hydrochloride
CAS:Diphenidol hydrochloride (Difenidol hydrochloride), a muscarinic antagonist, is employed as an anti-vertigo and as an antiemetic drug.Formula:C21H28ClNOPurity:99.15% - 99.38%Color and Shape:White SolidMolecular weight:345.91Ropivacaine hydrochloride
CAS:Ropivacaine hydrochloride (Ropivacaine monohydrochloride) is the hydrochloride salt of ropivacaine, a local anesthetic of the amide type with analgesic activityFormula:C17H26N2O·HClPurity:99.85% - 99.95%Color and Shape:SolidMolecular weight:310.86Oxybuprocaine hydrochloride
CAS:Oxybuprocaine hydrochloride (Oxybuprocaine HCl), a local anesthetic, is used especially in otolaryngology and ophthalmology.Formula:C17H29ClN2O3Purity:>99.99%Color and Shape:SolidMolecular weight:344.88Bupivacaine hydrochloride
CAS:Bupivacaine hydrochloride (Vivacaine) is a long-lasting, amide local anesthetic that blocks sodium channels, inhibiting nerve impulses and sensation.Formula:C18H28N2O·HClPurity:99.89% - 99.9%Color and Shape:White SolidMolecular weight:324.89NaV1.7 inhibitor-1
CAS:NaV1.7 inhibitor-1, an efficacious inhibitor of voltage-gated sodium channel (NaV) 1.7 (IC50 of 0.6 nM for hNaV1.7).Formula:C23H30FNO4SPurity:99.89%Color and Shape:SolidMolecular weight:435.55Ref: TM-T12181
1mg99.00€5mg241.00€1mL*10mM (DMSO)265.00€10mg385.00€25mg663.00€50mg888.00€100mg1,305.00€Lidocaine hydrochloride
CAS:Lidocaine HCl: local anesthetic, antiarrhythmic, stronger & longer-lasting than procaine but shorter than bupivacaine/prilocaine.Formula:C14H23ClN2OPurity:99.83% - 99.92%Color and Shape:SolidMolecular weight:270.798Ceratotoxin-1
Ceratotoxin-1 (CcoTx1) is a peptide toxin that functions as an inhibitor of various voltage-gated sodium channel subtypes.Formula:C172H256N52O50S6Purity:98%Color and Shape:SolidMolecular weight:4044.58XPC-7724
XPC-7724 is a selective inhibitor of the Nav1.6 channel, with an IC50 value of 0.078 μM. It is useful in research related to neurological disorders.Formula:C25H30FN5O2SMolecular weight:483.21042OD1
Activates rat Nav1.7, human Nav1.4, rat Nav1.6 (EC50: 7, 10, 47 nM); minimal on Nav1.2, 1.3, 1.5 (EC50 >3 μM); blocks fast inactivation; triggers pain.Formula:C308H466N90O95S8Purity:98%Color and Shape:SolidMolecular weight:7206.11-(1-Methyl-1h-pyrazol-4-yl)-ethanone
CAS:1-(1-Methyl-1h-pyrazol-4-yl)-ethanone is a high purity biochemical reagent that can be used in research related to life sciences.Formula:C6H8N2OPurity:99.92%Color and Shape:SolidMolecular weight:124.14Sodium Channel Targeted Library
A unique collection of xnum sodium channel blockers and agonists for high throughput and high content screening;Color and Shape:Odour SolidRef: TM-L7400
1mgTo inquire10μL*10mM (DMSO)To inquire20μL*10mM (DMSO)To inquire30μL*10mM (DMSO)To inquire50μL*10mM (DMSO)To inquire100μL*10mM (DMSO)To inquire250μL*10mM (DMSO)To inquireSodium Channel inhibitor 5
Sodium Channel inhibitor5 (compound 7d) is a potent sodium channel inhibitor with an IC50 of 2.7 μM, playing a significant role in antiarrhythmic research.Formula:C24H23F3N4O2Color and Shape:SolidMolecular weight:456.17731Nav1.8-IN-6
Nav1.8-IN-6 (Compound 2j) is a novel pyridinone amide Nav1.8 channel inhibitor with IC50 values of 513.33 nM in the resting state and 471.81 nM in the partially activated state. Nav1.8-IN-6 also exhibits analgesic activity.Formula:C19H17F6N3O2Color and Shape:SolidMolecular weight:433.1225GpTx-1
CAS:GpTx-1 exhibits potent selectivity as a NaV1.7 antagonist, demonstrating an inhibition concentration (IC50) of 10 nM [1].Formula:C176H271N53O45S7Purity:98%Color and Shape:SolidMolecular weight:4073.82Phrixotoxin 3
CAS:Potent NaV blocker: IC50 - 0.6 nM (NaV1.2), 42 nM (NaV1.3), 72 nM (NaV1.5); voltage-dependent inhibition.Formula:C176H269N51O48S6Purity:98%Color and Shape:SolidMolecular weight:4059.74
