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Sodium Channel

Sodium Channel

Sodium channels are essential membrane proteins that allow the passage of sodium ions (Na+) across the cell membrane, generating and propagating electrical signals in neurons, muscle cells, and other excitable tissues. These channels are vital for the initiation and conduction of action potentials, making them crucial in processes such as nerve impulse transmission, muscle contraction, and cardiac function. Dysregulation of sodium channels can lead to neurological disorders, arrhythmias, and chronic pain conditions. At CymitQuimica, we provide a variety of sodium channel modulators to support your research in neurobiology, cardiology, and pain management.

Found 202 products of "Sodium Channel"

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  • Amiloride hydrochloride

    CAS:
    <p>Amiloride hydrochloride (Amiloride HCl) 是上皮钠通道和尿激酶型纤溶酶原激活物受体的抑制剂,也是 polycystin-2通道阻断剂。</p>
    Formula:C6H9Cl2N7O
    Purity:99.72% - 99.95%
    Color and Shape:Physical Description Crystalline Solid Or Very Light Yellow Powder (Ntp 1992)
    Molecular weight:266.09
  • Butamben

    CAS:
    <p>Butamben (Butyl 4-aminobenzoate) is a long-duration local anesthetic used for the treatment of chronic pain.</p>
    Formula:C11H15NO2
    Purity:99.43%
    Color and Shape:Crystals From Alc Physical Description Yellow Powder Insoluble In Water (Ntp 1992)
    Molecular weight:193.24
  • Lidocaine hydrochloride

    CAS:
    <p>Lidocaine HCl: local anesthetic, antiarrhythmic, stronger &amp; longer-lasting than procaine but shorter than bupivacaine/prilocaine.</p>
    Formula:C14H23ClN2O
    Purity:99.81% - 99.92%
    Color and Shape:White Crystal Powder
    Molecular weight:270.798
  • Dibucaine

    CAS:
    <p>Dibucaine (Cinchocaine), a local anesthetic of the amide type, is now usually used for surface anesthesia.</p>
    Formula:C20H29N3O2
    Purity:99.698% - 99.88%
    Color and Shape:Colorless Or Almost Colorless Powder Solid
    Molecular weight:343.46
  • Diphenidol hydrochloride

    CAS:
    <p>Diphenidol hydrochloride (Difenidol hydrochloride), a muscarinic antagonist, is employed as an anti-vertigo and as an antiemetic drug.</p>
    Formula:C21H28ClNO
    Purity:99.15% - 99.33%
    Color and Shape:Crystals Soluble In Methanol Water
    Molecular weight:345.91
  • Methocarbamol

    CAS:
    <p>Methocarbamol (AHR 85) is a centrally acting muscle relaxant whose mode of action has not been established.</p>
    Formula:C11H15NO5
    Purity:99.96%
    Color and Shape:Crystals From Benzene Solid
    Molecular weight:241.24
  • Ranolazine dihydrochloride

    CAS:
    <p>Ranolazine 2HCl, an antianginal, treats arrhythmia by inhibiting sodium current without changing blood pressure or heart rate.</p>
    Formula:C24H35Cl2N3O4
    Purity:99.30% - >99.99%
    Color and Shape:White Crystalline Powder
    Molecular weight:500.46
  • Meticrane

    CAS:
    <p>Meticrane (Arresten) is a sulphonamide-derivative with thiazide-like diuretic activity.</p>
    Formula:C10H13NO4S2
    Purity:99.16%
    Color and Shape:Solid
    Molecular weight:275.34
  • Mebeverine hydrochloride

    CAS:
    <p>Mebeverine hydrochloride (Colofac Hydrochloride), a β-phenylethylamine derivative, is a potent α1 repector inhibitor, relaxing the muscles in and around the gut</p>
    Formula:C25H35NO5
    Purity:99.81% - 99.81%
    Color and Shape:Solid
    Molecular weight:429.55
  • Nav1.8-IN-4

    CAS:
    <p>Nav1.8-IN-4 is a potent Nav1.8 channel inhibitor with potential analgesic activity.Nav1.8-IN-4 can be used for pain and neurological related disorders.</p>
    Formula:C20H14F4N2O3
    Purity:99.83%
    Color and Shape:Soild
    Molecular weight:406.33
  • Phenazopyridine hydrochloride

    CAS:
    <p>Phenazopyridine HCl, an oral urinary analgesic, may cause nausea, anemia, and liver/kidney toxicity. Possibly carcinogenic.</p>
    Formula:C11H12ClN5
    Purity:99.27%
    Color and Shape:Brownish-Yellow Crystals Aqueous Solutions Are Yellow To Brick-Red And Slightly Acidic; They May Be Stabilized By The Addition
    Molecular weight:249.7
  • Lamotrigine

    CAS:
    <p>Lamotrigine (BW430C) is an Anti-epileptic Agent and Mood Stabilizer.</p>
    Formula:C9H7Cl2N5
    Purity:99.76% - 99.95%
    Color and Shape:White To Pale Cream-Colored Powder Crystals From Isopropanol Solid
    Molecular weight:256.09
  • Ropivacaine

    CAS:
    <p>Ropivacaine (LEA-103 HCl) is a local anaesthetic drug belonging to the amino amide group.</p>
    Formula:C17H26N2O
    Purity:97.75% - >99.99%
    Color and Shape:Solid
    Molecular weight:274.40
  • Oxcarbazepine

    CAS:
    <p>Oxcarbazepine (GP 47680), an anti-epileptic, reduces CNS disorganized electrical activity.</p>
    Formula:C15H12N2O2
    Purity:98.46%
    Color and Shape:Crystals From Ethanol Solid
    Molecular weight:252.27
  • Propafenone

    CAS:
    <p>Propafenone: a drug for ventricular arrhythmias with mild beta-blocker activity, prolongs refractory period, and reduces heart automaticity.</p>
    Formula:C21H27NO3
    Purity:99.02%
    Color and Shape:Solid
    Molecular weight:341.44
  • Oxybuprocaine hydrochloride

    CAS:
    <p>Oxybuprocaine hydrochloride (Oxybuprocaine HCl), a local anesthetic, is used especially in otolaryngology and ophthalmology.</p>
    Formula:C17H29ClN2O3
    Purity:>99.99%
    Color and Shape:White Crystalline Powder
    Molecular weight:344.88
  • Brompheniramine maleate

    CAS:
    <p>Brompheniramine maleate (Dimotane) is an antagonist against histamine H1 receptors.</p>
    Formula:C16H19BrN2·C4H4O4
    Purity:99.80%
    Color and Shape:Crystal Powder
    Molecular weight:435.31
  • Benzocaine

    CAS:
    <p>Benzocaine is a surface anesthetic that acts by preventing transmission of impulses along nerve fibers and at nerve endings.</p>
    Formula:C9H11NO2
    Purity:99.16% - 99.88%
    Color and Shape:Rhombohedra From Ether Drypowder
    Molecular weight:165.19
  • Amitriptyline hydrochloride

    CAS:
    <p>Amitriptyline hydrochloride (Annoyltin) is the hydrochloride salt of the tricyclic dibenzocycloheptadiene amitriptyline with antidepressant and antinociceptive</p>
    Formula:C20H24ClN
    Purity:97% - 99.94%
    Color and Shape:Crystals White To Off-White Powder
    Molecular weight:313.86
  • Mexiletine hydrochloride

    CAS:
    <p>Mexiletine hydrochloride is a lidocaine-like antiarrhythmic (Class IB) and anesthetic, stabilizing heartbeats by inhibiting sodium in cardiac cells.</p>
    Formula:C11H18ClNO
    Purity:99.88%
    Color and Shape:White To Off-White Solid
    Molecular weight:215.72
  • Topiramate

    CAS:
    <p>Topiramate (RWJ 17021) is a unique antiseizure medication that is used in the treatment of partial and generalized seizures.</p>
    Formula:C12H21NO8S
    Purity:99.79% - 99.92%
    Color and Shape:White To Off-White Crystalline Powder
    Molecular weight:339.36
  • BIIB 722 Mesylate

    CAS:
    <p>BIIB 722 Mesylate is a sodium-hydrogen exchange inhibitor with cardioprotective properties and can be used to study myocardial ischemia.</p>
    Formula:C19H23F3N6O5S
    Purity:99.57%
    Color and Shape:Soild
    Molecular weight:504.483
  • Tocainide

    CAS:
    <p>Tocainide is a blocker of the sodium channel and used for the treatment of tinnitus.</p>
    Formula:C11H16N2O
    Purity:99.84%
    Color and Shape:Solid
    Molecular weight:192.26
  • E 0747 FA


    <p>E 0747 FA is an antiarrhythmic compound that inhibits the voltage of action potential Vmax in Purkinje fibers of porcine heart.E 0747 FA inhibits Na channels in cardiac cells.</p>
    Formula:C22H30ClN3O6
    Purity:98.54%
    Color and Shape:Solid
    Molecular weight:467.94
  • Phenytoin

    CAS:
    <p>Phenytoin: a non-sedative hydantoin, antiepileptic with anticonvulsant effects, stabilizes neurons, prevents seizure spread, and relaxes muscles.</p>
    Formula:C15H12N2O2
    Purity:99.95%
    Color and Shape:Needles (Alcohol) Tasteless (Ntp 1992)
    Molecular weight:252.27
  • Bupivacaine hydrochloride

    CAS:
    <p>Bupivacaine hydrochloride (Vivacaine) is a long-lasting, amide local anesthetic that blocks sodium channels, inhibiting nerve impulses and sensation.</p>
    Formula:C18H28N2O·HCl
    Purity:99.9% - >99.99%
    Color and Shape:Solid
    Molecular weight:324.89
  • Vinpocetine

    CAS:
    <p>Vinpocetine (RGH-4405) is a selective inhibitor of cyclic GMP phosphodiesterase (PDE).</p>
    Formula:C22H26N2O2
    Purity:99.85% - 99.98%
    Color and Shape:White Crystalline Solid
    Molecular weight:350.45
  • Lidocaine Hydrochloride hydrate

    CAS:
    <p>Lidocaine Hydrochloride hydrate is an amide local anesthetic, has anti-inflammatory property.</p>
    Formula:C14H22N2O·HCl·H2O
    Purity:99.95%
    Color and Shape:Solid
    Molecular weight:288.82
  • Flunarizine dihydrochloride

    CAS:
    <p>Flunarizine dihydrochloride: a calcium blocker also targeting calmodulin and histamine H1, used for migraine, vertigo, vascular disease, and epilepsy aid.</p>
    Formula:C26H28Cl2F2N2
    Purity:99.53% - 99.89%
    Color and Shape:White Crystalline Powder Odorless And Tasteless
    Molecular weight:477.42
  • Eleclazine hydrochloride

    CAS:
    <p>Eleclazine hydrochloride (GS 6615 hydrochloride) is a novel inhibitor of late Na+ current (IC50: 0.7 uM).</p>
    Formula:C21H17ClF3N3O3
    Purity:99.86%
    Color and Shape:Solid
    Molecular weight:451.83
  • Lidocaine

    CAS:
    <p>Lidocaine, an amide local anesthetic, reduces pain and inflammation by dampening ICAM-1, cytokines, and neutrophil influx.</p>
    Formula:C14H22N2O
    Purity:99.95% - >99.99%
    Color and Shape:Needles From Benzene Or Alcohol Solid
    Molecular weight:234.34
  • Primidone

    CAS:
    <p>Primidone (NCI-C56360) is a potent anticonvulsant agent.</p>
    Formula:C12H14N2O2
    Purity:99.91%
    Color and Shape:Crystals (Ntp 1992)
    Molecular weight:218.25
  • NaV1.7 inhibitor-1

    CAS:
    <p>NaV1.7 inhibitor-1, an efficacious inhibitor of voltage-gated sodium channel (NaV) 1.7 (IC50 of 0.6 nM for hNaV1.7).</p>
    Formula:C23H30FNO4S
    Purity:99.89%
    Color and Shape:Solid
    Molecular weight:435.55
  • Ropivacaine hydrochloride

    CAS:
    <p>Ropivacaine hydrochloride (Ropivacaine monohydrochloride) is the hydrochloride salt of ropivacaine, a local anesthetic of the amide type with analgesic activity</p>
    Formula:C17H26N2O·HCl
    Purity:99.85% - 99.95%
    Color and Shape:Solid
    Molecular weight:310.86
  • PF-04885614

    CAS:
    <p>PF-04885614 is a potent inhibitor of NaV1.8, has potential for neurological and neurodevelopmental diseases treatment.</p>
    Formula:C13H14F3N3O
    Purity:98.02%
    Color and Shape:Solid
    Molecular weight:285.27
  • Tocainide hydrochloride

    CAS:
    <p>Tocainide hydrochloride (2-amino-n-(2,6-dimethylphenyl)propanamide hydrochloride) is a sodium channel blocker.</p>
    Formula:C11H17ClN2O
    Purity:97%
    Color and Shape:Solid
    Molecular weight:228.72
  • QX-314 chloride

    CAS:
    <p>QX-314 chloride is a membrane-impermeable permanently charged blocker of sodium channel.</p>
    Formula:C16H27ClN2O
    Purity:99.73%
    Color and Shape:Solid
    Molecular weight:298.85
  • Phenytoin sodium

    CAS:
    <p>Phenytoin sodium (Diphantoine) is an inactive stabilizer for voltage-gated sodium channel .</p>
    Formula:C15H11N2NaO2
    Purity:99.88% - 99.92%
    Color and Shape:Solid
    Molecular weight:274.25
  • Articaine hydrochloride

    CAS:
    <p>Articaine hydrochloride (Hoe-045) is a thiophene-containing local anesthetic pharmacologically similar to MEPIVACAINE.</p>
    Formula:C13H21ClN2O3S
    Purity:99.76%
    Color and Shape:White Crystalline Powder
    Molecular weight:320.84
  • DSP-2230

    CAS:
    <p>DSP-2230 is a selective blocker of Nav1.7/Nav1.8.</p>
    Formula:C20H20F3N5O2
    Purity:97.14%
    Color and Shape:Solid
    Molecular weight:419.4
  • Disopyramide

    CAS:
    <p>Disopyramide, or Triombrin, a class I anti-arrhythmic with membrane-stabilizing effects, has heart depressant, anticholinergic, and anesthetic properties.</p>
    Formula:C21H29N3O
    Purity:99.62%
    Color and Shape:Solid
    Molecular weight:339.47
  • LTGO-33

    CAS:
    <p>LTGO-33 is a voltage-gated sodium channel NaV1.8 inhibitor that inhibits NaV1.8, NaV1.1-NaV1.7, and NaV1.9.</p>
    Formula:C21H17F4N3O3S
    Purity:97.6%
    Color and Shape:Soild
    Molecular weight:467.44
  • Benzonatate (PEGn)

    CAS:
    <p>Benzonatate (PEGn) is a unique non-narcotic cough suppressant featuring sodium channel blocking properties and anesthetic effects on respiratory tract stretch receptors.</p>
    Formula:(C2H4O)nC12H17NO2
    Color and Shape:Solid
  • Zandatrigine

    CAS:
    <p>Zandatrigine (NBI-921352) is a blocker of sodium channel protein type 8 subunit alpha and can be used in studies about nervous system pathologies of epilepsy</p>
    Formula:C22H25FN4O2S2
    Purity:99.98%
    Color and Shape:Solid
    Molecular weight:460.59
  • GpTx-1 TFA


    <p>GpTx-1 TFA is a polypeptide NaV1.7 sodium channel antagonist isolated from the venom of the Chilean spider Grammostola porter. It exhibits potent inhibitory activity on the NaV1.7 channel with an IC50 value of 10 nM, demonstrating excellent selectivity over NaV1.4 (IC50 = 0.301 μM) and NaV1.5 (IC50 = 4.20 μM) with &gt;20-fold and &gt;950-fold selectivity, respectively.</p>
    Color and Shape:Odour Solid
  • Lifarizine FA


    <p>Lifarizine FA is a sodium channel blocker used in the treatment of neurological disorders and cardiovascular diseases, study of stroke.</p>
    Formula:C30H34N4O2
    Purity:99.55%
    Color and Shape:Solid
    Molecular weight:482.62
  • SLC26A3-IN-2

    CAS:
    <p>Vilobelimab (CaCP-29) is a human-mouse chimeric IgG antibody targeting human complement component 5a, a C5a inhibitor that inhibits neutrophil activation.</p>
    Formula:C19H13ClN2O2S
    Purity:99.86%
    Color and Shape:Solid
    Molecular weight:368.84
  • Halazone

    CAS:
    <p>Halazone (Pantocid) is fine white powder with an odor of chlorine. It has been widely used to disinfect drinking water.</p>
    Formula:C7H5Cl2NO4S
    Purity:98.64%
    Color and Shape:Physical Description Fine White Powder With An Odor Of Chlorine (Ntp 1992)
    Molecular weight:270.09
  • Solpecainol

    CAS:
    <p>solpecainol is a sodium channel blocker used in the study of neurological and cardiovascular diseases.</p>
    Formula:C18H23NO3
    Purity:99.71%
    Color and Shape:Soild
    Molecular weight:301.38
  • PF-06456384 trihydrochloride

    CAS:
    <p>PF-06456384 trihydrochloride is a selective NaV1.7 inhibitor acting through protein-ligand binding. intravenous infusion and pain research.</p>
    Formula:C35H35Cl3F3N7O3S2
    Purity:99.16%
    Color and Shape:Solid
    Molecular weight:829.18