PDE
Phosphodiesterases (PDEs) are enzymes that hydrolyze cyclic nucleotides, such as cAMP and cGMP, into their inactive forms, playing a key role in regulating intracellular signaling pathways. PDE inhibitors are used in the treatment of various conditions, including cardiovascular diseases, erectile dysfunction, and respiratory disorders, due to their ability to modulate cyclic nucleotide levels. At CymitQuimica, we provide a range of PDE inhibitors to support your research in cell signaling, pharmacology, and therapeutic development.
Found 165 products of "PDE"
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Amrinone
CAS:<p>Amrinone (Inocor) is a positive inotropic cardiotonic (cardiotonic agent) with vasodilator properties, phosphodiesterase 3 inhibitory activity.</p>Formula:C10H9N3OPurity:98.88% - 99.45%Color and Shape:SolidMolecular weight:187.2N-Methylbenzamide
CAS:<p>N-Methylbenzamide is a potent phosphodiesterase 10A (PDE10A) inhibitor,with anti-cancer activity.</p>Formula:C8H9NOPurity:99.83%Color and Shape:Physical Description Off-White Crystalline Solid (Ntp 1992)Molecular weight:135.16Zatolmilast
CAS:<p>Zatolmilast (BPN14770) is an allosteric inhibitor of selective phosphodiesterase 4D (PDE4D; IC50s: 7.8 nM and 7.4 nM for PDE4D7 and PDE4D3).</p>Formula:C21H15ClF3NO2Purity:98.20%Color and Shape:SolidMolecular weight:405.8Roflumilast
CAS:<p>Roflumilast (APTA 2217) is an orally available, long-acting inhibitor of phosphodiesterase (PDE) type 4 (PDE4), with anti-inflammatory and potential</p>Formula:C17H14Cl2F2N2O3Purity:99.76% - 99.86%Color and Shape:SolidMolecular weight:403.21Pumafentrine
CAS:<p>Pumafentrine（BY 343） is a dual PDE3/PDE4 inhibitor that reduces clinical scores and TNF expression in experimental colitis in mice.</p>Formula:C29H39N3O3Purity:>99.99%Color and Shape:SolidMolecular weight:477.64Cilostazol
CAS:<p>Cilostazol (OPC 21) is a Phosphodiesterase 3 Inhibitor. The mechanism of action of cilostazol is as a Phosphodiesterase 3 Inhibitor.</p>Formula:C20H27N5O2Purity:99.58% - 99.90%Color and Shape:Off-White SolidMolecular weight:369.46Pimobendan
CAS:<p>Pimobendan (UD-CG 115 BS) is a selective inhibitor of PDE3 (IC50: 0.32 μM).</p>Formula:C19H18N4O2Purity:99.91%Color and Shape:SolidMolecular weight:334.37ITI-214
CAS:<p>ITI-214 is a picomolar PDE1 inhibitor with excellent selectivity against other PDE family members, exhibits potent PDE1 inhibitory activity.</p>Formula:C29H29FN7O5PPurity:98.21%Color and Shape:SolidMolecular weight:605.56T-0156
CAS:<p>T-0156 is a PEG5 inhibitor that inhibits the hydrolysis of cyclic guanosine monophosphate (cGMP) with low affinity for PDE6, PDE1, PDE2, PDE3 and PDE4.</p>Formula:C31H29N5O7Purity:98.53% - 98.76%Color and Shape:SoildMolecular weight:583.59EMD57439
CAS:<p>EMD57439 is a selective PDE-III inhibitor, showing no significant increase in c-AMP concentration and producing little change in Ca(50).</p>Formula:C22H23N3O4SPurity:99.38% - 99.57%Color and Shape:SolidMolecular weight:425.5NSP-805
CAS:<p>NSP-805 is a potent and selective guinea pig cardiac phosphodiesterase 3 (PDE3) inhibitor.</p>Formula:C17H19N3O2Purity:99.85%Color and Shape:SolidMolecular weight:297.35ATX inhibitor 1
CAS:<p>ATX inhibitor 1 is a potent ATX inhibitor (IC50: 1.23 nM, FS-3 and 2.18 nM, bis-pNPP).</p>Formula:C21H23Cl2N2O6PPurity:99.52%Color and Shape:SolidMolecular weight:501.3Carbodenafil
CAS:<p>Carbodenafil is a Sildenafil related compound found in healthy foods. Sildenafil is a PDE5 inhibitor (IC50: 5.22 nM).</p>Formula:C24H32N6O3Purity:98.96% - 99.89%Color and Shape:SolidMolecular weight:452.55Trapidil
CAS:<p>Trapidil (Avantrin) is a coronary vasodilator agent.</p>Formula:C10H15N5Purity:99.42%Color and Shape:SolidMolecular weight:205.26Milrinone
CAS:<p>Milrinone (Win 47203) is a Phosphodiesterase 3 Inhibitor. The mechanism of action of milrinone is as a Phosphodiesterase 3 Inhibitor.</p>Formula:C12H9N3OPurity:99.22% - 99.92%Color and Shape:SolidMolecular weight:211.22MR-L2
CAS:<p>MR-L2 is a reversible and noncompetitive allosteric activator of long-isoform phosphodiesterase-4 (PDE4).</p>Formula:C19H16Cl3FN4OPurity:98.09% - 98.94%Color and Shape:SolidMolecular weight:441.71PDE4B-IN-4
<p>PDE4B-IN-4 is an inhibitor of PDE4B (IC50: 2.82 nM) and TNF-α (IC50: 7.20 nM). It demonstrates anti-inflammatory properties by reducing neutrophilia in a mouse model of lipopolysaccharide (LPS)-induced sepsis.</p>Formula:C26H27N5O5Color and Shape:SolidMolecular weight:489.52Acetildenafil
CAS:<p>Acetildenafil is an analog of the phosphodiesterase inhibitor sildenafil.</p>Formula:C25H34N6O3Color and Shape:Off-White To Pale Yelow SolidMolecular weight:466.58WAY-313170
CAS:<p>WAY-313170 Inhibits hedgehog signaling and phosphodiesterase.</p>Formula:C19H17ClN2O2S2Purity:99.3%Color and Shape:SolidMolecular weight:404.93FCPR03
CAS:<p>FCPR03 is a selective inhibitor of phosphodiesterase 4 (PDE4) with IC50s of 31 nM, 47 nM, and 60 nM for PDE4B1, PDE4D7, and PDE4 catalytic domain, respectively.</p>Formula:C15H19F2NO3Purity:99.94%Color and Shape:SolidMolecular weight:299.31BC 11-38
CAS:<p>BC 11-38 is a potent, selective PDE biodepressant which is mainly effective against PDE11 (IC50 : 0.28 μM).</p>Formula:C15H16N2OS2Purity:98.95% - 99.28%Color and Shape:SolidMolecular weight:304.43OPC18750 HCl
CAS:<p>OPC18750 HCl is a phosphodiesterase inhibitor with positive inotropic effects that can be used to study asthma, cancer, diabetes, and psychiatric disorders.</p>Formula:C20H23ClN2O4Purity:98.92%Color and Shape:SoildMolecular weight:390.86PDE10A-IN-5
<p>PDE10A-IN-5 (Compound A30) is an orally active inhibitor of phosphodiesterase 10A (PDE10A) with an IC50 value of 3.5 nM. By inhibiting PDE10A, it activates the cyclic adenosine monophosphate (cAMP)-related signaling pathway, exhibiting activity against pulmonary vascular remodeling. This compound is applicable to research in the field of pulmonary arterial hypertension.</p>Color and Shape:Odour SolidDazonone
CAS:<p>Dazonone (Imidazo[2,1-b]quinazolin-2(3H)-one, 6-chloro-1,5-dihydro-3-methyl-) is a specific PDE III inhibitors.</p>Formula:C11H10ClN3OPurity:99.54% - 99.73%Color and Shape:SolidMolecular weight:235.67PDE5-IN-9
CAS:<p>WAY-639921 treats cardiovascular and respiratory conditions by inhibiting PDE1c.</p>Formula:C18H14N4SPurity:99.98%Color and Shape:SolidMolecular weight:318.4Enpp-1-IN-14
CAS:<p>Enpp-1-IN-14: potent ENPP1 inhibitor, IC50 = 32.38 nM, exhibits anti-tumor properties.</p>Formula:C15H22ClN5O4SPurity:99.83%Color and Shape:SoildMolecular weight:403.88Oglemilast
CAS:<p>Oglemilast (GRC 3886) suppresses pulmonary cell infiltration, including eosinophilia and neutrophilia in vitro and in vivo.</p>Formula:C20H13Cl2F2N3O5SPurity:99.82%Color and Shape:SolidMolecular weight:516.3BAY 2666605
CAS:<p>BAY 2666605 is an orally active inhibitor of PDE3A and PDE3B with IC50s of 87 nM and 50 nM, respectively. BAY 2666605 has anticancer effects.</p>Formula:C17H12F4N2O2Purity:99.81%Color and Shape:SolidMolecular weight:352.28ONO-8430506
CAS:<p>ONO-8430506 is an orally available, potent autotaxin (ATX)/ENPP2 inhibitor (IC90: 100 nM) that inhibits ATX activity in mouse plasma.</p>Formula:C27H28FN3O3Purity:98.34%Color and Shape:SolidMolecular weight:461.53BI 1015550
CAS:<p>Nerandomilast (BI 1015550) is an orally active PDE4B inhibitor with IC50 of 7.2 nM.Cost-effective and quality-assured.</p>Formula:C20H25ClN6O2SPurity:98.06% - 99.71%Color and Shape:SoildMolecular weight:448.97Arofylline
CAS:<p>Arofylline (LAS 31025) is a PDE4 inhibitor and can be used for asthma studies.</p>Formula:C14H13ClN4O2Purity:98.19%Color and Shape:SolidMolecular weight:304.73cis-Tadalafil
CAS:<p>Tadalafil: a carboline-based PDE5 inhibitor, treats erectile dysfunction, prostatic hyperplasia, and pulmonary hypertension.</p>Formula:C22H19N3O4Purity:99.89%Color and Shape:SolidMolecular weight:389.4UK 227786
CAS:<p>UK 227786 is an inhibitor of phosphodiesterase 5 (PDE5), used for treatment of prostatic diseases.</p>Formula:C22H22Cl2N4O4Purity:99.9%Color and Shape:SoildMolecular weight:477.34(1R,2R)-MK-8189
CAS:<p>(1R,2R)-MK-8189 is an isomer of MK-8189, a potent and selective pyrimidine PDE10A inhibitor.</p>Formula:C19H22N6OSPurity:>99.99% - >99.99%Color and Shape:SoildMolecular weight:382.48Theodrenaline hydrochloride
CAS:<p>Theodrenaline hydrochloride is an inhibitor targeting SARS-CoV-2 for the study of hypotension induced by spinal anesthesia.</p>Formula:C17H22ClN5O5Purity:98% - 98.18%Color and Shape:SoildMolecular weight:411.84Anti-ALDH7A1 Antibody (3P955)
<p>Anti-ALDH7A1 Antibody (3P955) is a Rabbit antibody targeting ALDH7A1. Anti-ALDH7A1 Antibody (3P955) can be used in WB,ELISA,IP.</p>Color and Shape:Odour LiquidALDH7A1 Protein, Human, Recombinant (His)
<p>ALDH7A1 (Aldehyde dehydrogenase 7 family, member A1) is a member of subfamily 7 in the aldehyde dehydrogenase family.</p>Color and Shape:Lyophilized PowderMolecular weight:56 kDa (predicted); 56 kDa (reducing conditions)PF-05180999
CAS:<p>α-2,3-sialyltransferase-IN-1 (Lith-O-Asp analog) is an α-2,3-sialyltransferase inhibitor with anticancer activity.</p>Formula:C19H17F3N8Purity:99.43% - 99.82%Color and Shape:SolidMolecular weight:414.39Anti-ALDH7A1 Antibody-FITC (5P692)
<p>Anti-ALDH7A1 Antibody-FITC (5P692) is a FITC-conjugated Rabbit antibody targeting ALDH7A1. Anti-ALDH7A1 Antibody-FITC (5P692) can be used in FCM.</p>Color and Shape:Odour LiquidBAY 73-6691 racemate
CAS:<p>BAY 73-6691 racemate (Rac-BAY 73-6691) is a phosphodiesterase 9A (PDE9A) inhibitor, useful for studying Parkinson’s disease.</p>Formula:C15H12ClF3N4OColor and Shape:SolidMolecular weight:356.73Anti-ALDH7A1 Antibody (6G475)
<p>Anti-ALDH7A1 Antibody (6G475) is a Mouse antibody targeting ALDH7A1. Anti-ALDH7A1 Antibody (6G475) can be used in IHC-P.</p>Color and Shape:Odour LiquidAutotaxin modulator 1
CAS:<p>Autotaxin modulator 1 is a new modulator of Autotaxin.</p>Formula:C28H31F6NO3Purity:99.46%Color and Shape:SolidMolecular weight:543.54ENPP1 Inhibitor C
CAS:<p>ML-354 (VU0099704) is an antagonist with and PAR4 for the study of cardiovascular diseases.</p>Formula:C15H18N6Purity:99.28%Color and Shape:SolidMolecular weight:282.34Anti-ALDH7A1 Antibody (1G435)
<p>Anti-ALDH7A1 Antibody (1G435) is a Mouse antibody targeting ALDH7A1. Anti-ALDH7A1 Antibody (1G435) can be used in ELISA.</p>Color and Shape:Odour LiquidN-Ethyl tadalafil
CAS:<p>N-Ethyl tadalafil (NEthyl tadalafil) is a PDE inhibitor used in the study of cardiovascular disease.</p>Formula:C23H21N3O4Purity:99.58%Color and Shape:SolidMolecular weight:403.43Anti-ALDH7A1 Antibody (5P692)
<p>Anti-ALDH7A1 Antibody (5P692) is a Rabbit antibody targeting ALDH7A1. Anti-ALDH7A1 Antibody (5P692) can be used in FCM,ICC/IF.</p>Color and Shape:Odour LiquidBay 60-7550
CAS:<p>Bay 60-7550 is a PDE2 inhibitor that exerts positive inotropic effects in the rat heart by increasing PKA-mediated phosphorylation.</p>Formula:C27H32N4O4Purity:98.14%Color and Shape:SolidMolecular weight:476.57PF-05085727
CAS:<p>PF-05085727 inhibits PDE2A >4,000-fold selectivity over PDE1 and PDE3-11.</p>Formula:C20H18F3N7Purity:98%Color and Shape:SolidMolecular weight:413.4THPP-1
CAS:<p>THPP-1 is a potent and orally bioavailable inhibitor of PDE10A(Ki of 1 nM and 1.3 nM for human and rat PDE10A, respectively).</p>Formula:C23H21ClN6O3Purity:99.46%Color and Shape:SolidMolecular weight:464.9PF-8380
CAS:<p>PF-8380 is an effective and orally available autotaxin inhibitor (IC50: 2.8 nM, in isolated enzyme assay; 101 nM, in the human whole blood).</p>Formula:C22H21Cl2N3O5Purity:98.70% - 99.25%Color and Shape:SolidMolecular weight:478.33PQ-10
CAS:<p>PQ-10 (A-844337) is a PDE-10 inhibitor. PQ-10 induces brain glucose metabolism patterns, which may be a potential translational biomarker.</p>Formula:C22H21N5O3Purity:99.86%Color and Shape:SolidMolecular weight:403.43Roflumilast N-oxide
CAS:<p>Roflumilast N-oxide is an inhibitor of PDE type 4.</p>Formula:C17H14Cl2F2N2O4Purity:98.19% - 99.69%Color and Shape:SolidMolecular weight:419.21Balipodect
CAS:<p>Balipodect (TAK063) is a highly effective and selective PDE10A inhibitor (IC50: 0.30 nM); Its selectivity is >15000-fold over other PDEs.</p>Formula:C23H17FN6O2Purity:98% - 99.79%Color and Shape:SolidMolecular weight:428.42Irsogladine
CAS:<p>Irsogladine (Dicloguamine) is an anti-ulcer agent that promotes gap junction intercellular communication via M1 muscarinic acetylcholine receptor binding.</p>Formula:C9H7Cl2N5Purity:99.74% - 99.91%Color and Shape:White Or Colorless Crystal Or Crystalline Powder Odorless Slightly BitterMolecular weight:256.09K-Ras-PDEδ-IN-1
CAS:<p>K-Ras-PDEδ-IN-1 is a potent inhibitor of competitive K-Ras-PDEδ.It binds to the farnesyl binding pocket of PDEδ(Kd of 8 nM).</p>Formula:C25H26FN5O2Purity:99.48%Color and Shape:SolidMolecular weight:447.5Cilomilast
CAS:<p>Cilomilast (SB-207499) is a potent PDE4 inhibitor with IC50 of about 110 nM, has anti-inflammatory activity and low central nervous system activity. Phase 3.</p>Formula:C20H25NO4Purity:97.37% - 99.52%Color and Shape:White SolidMolecular weight:343.42ICI 63197
CAS:<p>ICI 63197 (2-Amino-6-methyl-4-propyl-[1,2,4]triazolo[1,5-a]pyrimidin-5(4H)-one) is a PDE4 inhibitor.</p>Formula:C9H13N5OPurity:99.70%Color and Shape:White SolidMolecular weight:207.23IBMX
CAS:<p>IBMX (Methylisobutylxanthine) is a broad-spectrum phosphodiesterase (PDE) inhibitor with inhibitory activity against PDE3, PDE4, and PDE5 (IC50=6.5/26.3/31.7 μM</p>Formula:C10H14N4O2Purity:98% - >99.99%Color and Shape:Off-WhiteMolecular weight:222.242,5-dichloro-4-(difluoromethoxy)-N,N-dimethylbenzene-1-sulfonamide
CAS:<p>2,5-dichloro-4-(difluoromethoxy)-N,N-dimethylbenzene-1-sulfonamide is a PDE inhibitor.</p>Formula:C9H9Cl2F2NO3SPurity:98.60%Color and Shape:SolidMolecular weight:320.14Olprinone
CAS:<p>Olprinone (Loprinone)(Loprinone) is a selective phosphodiesterase 3 (PDE3) inhibitor.Olprinone has been reported to improve microcirculation and attenuate</p>Formula:C14H10N4OPurity:99.68%Color and Shape:SolidMolecular weight:250.26HA130
CAS:<p>HA130 is a selective ATX (autotaxin) inhibitor.</p>Formula:C24H19BFNO5SPurity:98.26% - ≥95%Color and Shape:SolidMolecular weight:463.29Ro 20-1724
CAS:<p>Ro 20-1724 (4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone) is a widely used inhibitor of cyclic nucleotide phosphodiesterase with IC50 of 2.0 μM and Ki of 3.1</p>Formula:C15H22N2O3Purity:98.82% - 99.79%Color and Shape:SolidMolecular weight:278.35Mardepodect
CAS:<p>Mardepodect (PF-2545920) is a phosphodiesterase inhibitor selective for the PDE10A subtype with an IC50 of 0.37 nM, >1000-fold selectivity over PDE.</p>Formula:C25H20N4OPurity:99.81% - 99.94%Color and Shape:SolidMolecular weight:392.45BW-A 78U
CAS:<p>BW-A 78U is a PDE4 inhibitor (IC50: 3 μM). It is not inhibition on the lipopolysaccharide (LPS)-induced TNF-α release.</p>Formula:C13H12FN5Purity:99.45%Color and Shape:SolidMolecular weight:257.27MBCQ
CAS:<p>MBCQ is an inhibitor of cGMP-specific phosphodiesterase PDE5.</p>Formula:C16H12ClN3O2Purity:99.45%Color and Shape:SolidMolecular weight:313.74HA 155
CAS:<p>HA 155 (Autotaxin Inhibitor IV) is a boronic acid-based compound, inhibiting ATX with IC50 of 5.7 nM by selectively binding to its catalytic threonine.</p>Formula:C24H19BFNO5SPurity:99.88%Color and Shape:SolidMolecular weight:463.29Ibudilast
CAS:<p>Ibudilast (MN-166)(KC-404;AV-411;MN-166) is a relatively nonselective phosphodiesterase inhibitor. It is approved for use as an anti-inflammatory in Japan.</p>Formula:C14H18N2OPurity:99.83% - >99.99%Color and Shape:White SolidMolecular weight:230.31ML-030
CAS:<p>ML-030 is a potent PDE4 inhibitor, selective for subtypes (A1, B1, B2, C1, D2) with IC50 ranging from 6.7 to 452 nM.</p>Formula:C20H20N4O4SPurity:97.93%Color and Shape:SolidMolecular weight:412.46SEP-0372814
CAS:<p>SEP-0372814 is a potent inhibitor of PDE10.</p>Formula:C21H19N7Purity:99.29%Color and Shape:SolidMolecular weight:369.42YM976
CAS:<p>YM976 is an orally active PDE4 inhibitor (IC50:2.2 nM)</p>Formula:C17H16ClN3OPurity:99.84%Color and Shape:SolidMolecular weight:313.78Cilostamide
CAS:<p>Cilostamide (OPC3689) is a selective phosphodiesterase (PDE)3A and PDE3B inhibitor(IC50 values of 27 and 50 nM, respectively)</p>Formula:C20H26N2O3Purity:98.87%Color and Shape:White To Off-White SolidMolecular weight:342.43D159687
CAS:<p>D159687 is a selective PDE4D inhibitor,had a procognitive profile as it improved memory in the novel object recognition test but had no antidepressant benefit.</p>Formula:C21H19ClN2O2Purity:97.57%Color and Shape:SolidMolecular weight:366.84RS-25344 hydrochloride
CAS:<p>RS 25344 hydrochloride is a phosphodiesterase (PDE) 4 inhibitor</p>Formula:C19H14ClN5O4Purity:99.25%Color and Shape:SolidMolecular weight:411.8BRL-50481
CAS:<p>BRL-50481 is a novel and selective inhibitor of PDE7 with IC50s of 0.15, 12.1, 62 and 490 μM for PDE7A, PDE7B, PDE4 and PDE3, respectively.</p>Formula:C9H12N2O4SPurity:99.66%Color and Shape:SolidMolecular weight:244.27Piclamilast
CAS:<p>Piclamilast (RP 73401) is a PDE4 inhibitor.</p>Formula:C18H18Cl2N2O3Purity:98.28% - 99.57%Color and Shape:SolidMolecular weight:381.25Ensifentrine
CAS:<p>Ensifentrine (Ensifentrinum) is a PDE3/4 inhibitor, although its affinity for PDE3(IC50: 0.4 nM) is 3,440 times higher than that for PDE4(IC50: 1479 nM), that</p>Formula:C26H31N5O4Purity:99.76% - 99.94%Color and Shape:SolidMolecular weight:477.56Z-HA155
CAS:<p>Z-HA155 (CS-963) selectively and potently inhibits autotaxin with an IC50 of 5.7 nM.</p>Formula:C24H19BFNO5SPurity:99.18%Color and Shape:SolidMolecular weight:463.29Crisaborole
CAS:<p>Crisaborole (AN-2728) is a Phosphodiesterase 4 Inhibitor.</p>Formula:C14H10BNO3Purity:99.70%Color and Shape:SolidMolecular weight:251.05Udenafil
CAS:<p>Udenafil is an inhibitor of PDE5 .</p>Formula:C25H36N6O4SPurity:99.90%Color and Shape:Off-White SolidMolecular weight:516.66GSK256066
CAS:<p>GSK256066 is a selective PDE4B(equal affinity to isoforms A-D) inhibitor with IC50 of 3.2 pM, >380, 000-fold selectivity versus PDE1/2/3/5/6 and >2500-fold</p>Formula:C27H26N4O5SPurity:99.60% - 99.66%Color and Shape:SolidMolecular weight:518.58Nortadalafil
CAS:<p>Nortadalafil, a demethylated form of Tadalafil, is a PDE5 inhibitor used to treat ED and pulmonary arterial hypertension as Adcirca.</p>Formula:C21H17N3O4Purity:99.42%Color and Shape:SolidMolecular weight:375.38Homo Sildenafil
CAS:<p>Homo Sildenafil is an analog of Sildenafil, It acts as a phosphodiesterase inhibitor.</p>Formula:C23H32N6O4SPurity:99.88%Color and Shape:White SolidMolecular weight:488.6GEBR-7b
CAS:<p>GEBR-7b (3-(Cyclopentyloxy)-4-methoxybenzaldehyde) is a phosphodiesterase-4 (PDE4) inhibitor.</p>Formula:C13H16O3Purity:99.533%Color and Shape:SolidMolecular weight:220.26Enoximone
CAS:<p>Enoximone is a selective inhibitor of phosphodiesterase III (PDE3), with treatment of congestive heart failure.</p>Formula:C12H12N2O2SPurity:98.53%Color and Shape:SolidMolecular weight:248.3MY-5445
CAS:<p>MY-5445 (N-(3-chlorophenyl)-4-phenylphthalazin-1-amine) is a specific inhibitor of phosphodiesterase type 5 (PDE5).</p>Formula:C20H14ClN3Purity:99.77%Color and Shape:SolidMolecular weight:331.8Amino Tadalafil
CAS:<p>Amino tadalafil is a potent phosphodiesterase 5 (PDE5) inhibitor.</p>Formula:C21H18N4O4Purity:99.85%Color and Shape:White PowderMolecular weight:390.39Sildenafil Mesylate
CAS:<p>Sildenafil Mesylate is a mesylate form of Sildenafil, an inhibitor of Phosphodiesterase 5.</p>Formula:C22H30N6O4S·xCH4O3SPurity:99.84%Color and Shape:SolidMolecular weight:570.68Lodenafil
CAS:<p>Lodenafil (Hydroxyhomosildenafil) is a potent PDE5 inhibitor, with treatment of erectile dysfunction (ED)</p>Formula:C23H32N6O5SPurity:99.92%Color and Shape:SolidMolecular weight:504.6[11C]MP 10
CAS:<p>[11C]MP 10 (PF-2545920), a specific and effective PDE10A inhibitor (IC50=0.37 nM), is with more than1000-fold specificity activity over the PDE.</p>Formula:C25H20N4OPurity:99.5%Color and Shape:SolidMolecular weight:391.45Osoresnontrine
CAS:<p>Osoresnontrine is a potent and selective inhibitor of PDE9A (IC50 of 52 nM),and can be used in the research of memory.</p>Formula:C16H17N5O2Purity:99.93%Color and Shape:SolidMolecular weight:311.34CP671305
CAS:<p>CP671305 is an orally active, potent and selective inhibitor of phosphodiesterase-4-D.</p>Formula:C23H19FN2O7Purity:99.39%Color and Shape:SolidMolecular weight:454.4Ziritaxestat
CAS:<p>Ziritaxestat (GLPG1690), an autotaxin inhibitor, currently being evaluated in an exploratory phase 2 study in idiopathic pulmonary fibrosis patients.</p>Formula:C30H33FN8O2SPurity:97% - 99.85%Color and Shape:SolidMolecular weight:588.7PDE10-IN-1
CAS:<p>PDE10-IN-1 (SEP-0372814) is used for treating CNS and metabolic disorders.</p>Formula:C21H19N7Purity:99.65%Color and Shape:SolidMolecular weight:369.42RS-25344
CAS:<p>RS-25344: a strong PDE4 blocker, curbs eosinophil movement, boosts sperm motility in vitro.</p>Formula:C19H13N5O4Purity:98.98%Color and Shape:SolidMolecular weight:375.34Lotamilast
CAS:<p>Lotamilast (RVT-501) is a phosphodiesterase 4 (PDE-4) inhibitor (IC50: 2.8 nM) potentially for the treatment of atopic dermatitis.</p>Formula:C26H24N4O5Purity:97.03% - 99.29%Color and Shape:SolidMolecular weight:472.49Enpp-1-IN-1
CAS:<p>Enpp-1-IN-1 is an inhibitor of Ectonucleotide pyrophosphatase-phosphodiesterase 1 (enpp-1)</p>Formula:C17H17N3O3SPurity:97.52%Color and Shape:SolidMolecular weight:343.4GSK256066 Trifluoroacetate
CAS:<p>GSK 256066 Trifluoroacetate: selective PDE4 inhibitor, IC50: 3.2 pM for PDE4B, treats COPD.</p>Formula:C29H27F3N4O7SColor and Shape:SolidMolecular weight:632.61Crisaborole-d4
<p>Crisaborole-d4 (AN-2728-d4) is the deuterated form of Crisaborole. Crisaborole is a PDE4 inhibitor and also a cytokine release inhibitor.</p>Formula:C14H6D4BNO3Color and Shape:SolidMolecular weight:255.07ent-Tadalafil
CAS:<p>ent-Tadalafil (ent-IC-351), compound (6S,12aS), is a inactive cis-enantiomer of compound (6R,12aS).</p>Formula:C22H19N3O4Purity:98%Color and Shape:SolidMolecular weight:389.4Deltarasin
CAS:<p>Deltarasin is a small molecular inhibitor of KRAS-PDEδ interaction with Kd of 38 nM for binding to purified PDEδ.</p>Formula:C40H37N5OPurity:99.4%Color and Shape:SolidMolecular weight:603.75
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