Carbonic Anhydrase
Carbonic anhydrase is an enzyme that catalyzes the reversible conversion of carbon dioxide and water into bicarbonate and protons. This enzyme plays a crucial role in maintaining acid-base balance, respiration, and the transport of carbon dioxide in the blood. Inhibitors of carbonic anhydrase are used in the treatment of glaucoma, epilepsy, and altitude sickness, as well as in research on acid-base homeostasis and gas exchange. At CymitQuimica, we offer a range of high-quality carbonic anhydrase inhibitors and reagents to support your research in enzymology, respiratory physiology, and therapeutic development.
Found 177 products of "Carbonic Anhydrase"
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Benzthiazide
CAS:<p>Benzthiazide treats edema and hypertension by promoting diuresis and inhibiting kidney Na+/Cl- reuptake, but may reduce potassium and raise uric acid.</p>Formula:C15H14ClN3O4S3Purity:99.34% - 99.79%Color and Shape:Crystals From Acetone SolidMolecular weight:431.94Methazolamide
CAS:<p>Methazolamide (CL 8490) is a carbonic anhydrase inhibitor that is used as a diuretic and in the treatment of glaucoma.</p>Formula:C5H8N4O3S2Purity:99.31% - 99.77%Color and Shape:Crystals From Water SolidMolecular weight:236.27Tioxolone
CAS:<p>Tioxolone is a metalloenzyme carbonic anhydrase I inhibitor.</p>Formula:C7H4O3SPurity:97.79%Color and Shape:Light Yellow To Beige PowderMolecular weight:168.17Zonisamide
CAS:<p>Zonisamide (AD 810), a sulfonamide anticonvulsant, is approved for use as an adjunctive treatment in adults with partial-onset seizures.</p>Formula:C8H8N2O3SPurity:99.05% - 99.9%Color and Shape:Off-White PowderMolecular weight:212.23Topiramate
CAS:<p>Topiramate (RWJ 17021) is a unique antiseizure medication that is used in the treatment of partial and generalized seizures.</p>Formula:C12H21NO8SPurity:99.79% - 99.92%Color and Shape:White To Off-White Crystalline PowderMolecular weight:339.36Methocarbamol
CAS:<p>Methocarbamol (AHR 85) is a centrally acting muscle relaxant whose mode of action has not been established.</p>Formula:C11H15NO5Purity:99.96%Color and Shape:Crystals From Benzene SolidMolecular weight:241.24pNNP
CAS:<p>pNNP is a substrate for PP2C assays and inhibits β-carbonic anhydrase, α-carbonate dehydrogenase, and H. pylori.</p>Formula:C6H6NO6PPurity:99.73%Color and Shape:SolidMolecular weight:219.09Brinzolamide
CAS:<p>Brinzolamide (AL-4862) is a Carbonic Anhydrase Inhibitor. The mechanism of action of brinzolamide is as a Carbonic Anhydrase Inhibitor.</p>Formula:C12H21N3O5S3Purity:99.84% - >99.99%Color and Shape:Crystalline SolidMolecular weight:383.51Actarit
CAS:<p>Actarit (4-acetylaminophenylacetic acid) is an anti-inflammatory drug.</p>Formula:C10H11NO3Purity:99.64% - 99.74%Color and Shape:White Or Off-White Crystal Or Crystalline SolidMolecular weight:193.2Acipimox
CAS:<p>Acipimox (K-9321), a niacin derivative, treats hyperlipidemia in type 2 diabetics.</p>Formula:C6H6N2O3Purity:98.98%Color and Shape:Low Yellow Liquid Or CrystallineMolecular weight:154.12CA Ⅱ-IN-1
<p>CAⅡ-IN-1 (compound 2i) is an inhibitor of the CA Ⅱ isozyme, exhibiting an IC50 of 0.44 µM. This compound is utilized in metabolic research.</p>Formula:C18H19NO6SColor and Shape:SolidMolecular weight:377.41Carbonic anhydrase inhibitor 30
<p>Carbonic anhydrase inhibitor30 (compound 17) is an inhibitor of carbonic anhydrase with Ki values of 2.13 μM for hCA I and 0.161 μM for hCA II[1].</p>Formula:C23H22FN3O5SColor and Shape:SolidMolecular weight:471.12642CA IX/VEGFR-2-IN-3
<p>CAIX/VEGFR-2-IN-3 (Compound 6i) is an inhibitor of Carbonic Anhydrase IX and VEGFR-2, with IC50 values of 41 and 48 nM, respectively. It exhibits anticancer activity by inhibiting the growth of MCF-7 breast cancer cells (IC50 of 22.33 μM) and mouse fibroblast cell line 3T3, where cell viability is reduced to below 40% at a concentration of 100 μM. This compound is applicable for research in the field of cancer treatment.</p>Formula:C19H16ClN3O5S2Color and Shape:SolidMolecular weight:465.93hCA/VEGFR-2-IN-3
<p>hCA/VEGFR-2-IN-3 (compound 8j) is an indolinonylbenzenesulfonamide with potential as a dual inhibitor of cancer-associated hCA IX/XII and VEGFR-2.</p>Formula:C24H28N6O6SPurity:98%Color and Shape:SolidMolecular weight:528.58Phenylsulfamide
CAS:<p>Phenylsulfamide (Compound 10), acting as an inhibitor of human carbonic anhydrase-II (hCA-II), exhibits a dissociation constant (Kd) of 45.50 μM and an</p>Formula:C6H8N2O2SColor and Shape:SolidMolecular weight:172.2hCAIX-IN-19
<p>hCAIX-IN-19 is a sulfonamide inhibitor with an inhibition constant (KI) of 6.2 nM for hCAIX, exhibiting significant selectivity towards hCAIX over hCAI (hCA I/</p>Color and Shape:Odour SolidCAIX/CAXII-IN-3
<p>CAIX/CAXII-IN-3 (compound 11) serves as an inhibitor for CAIX/CAXII, exhibiting an IC50 value of less than 65 nM. Additionally, this compound effectively inhibits the proliferation of human melanoma cells.</p>Color and Shape:Odour SolidCAIX/CAXII-IN-4
<p>CAIX/CAXII-IN-4 (Compound 7h) is an inhibitor of carbonic anhydrase (CA) that binds to CAIX, CA XII, and CAII with Ki values of 1.324 μM, 0.435 μM, and 3.035 μM, respectively. This compound exhibits broad-spectrum anti-tumor activity and inhibits the proliferation of central nervous system tumor cells U251, with a GI50 of 0.361 μM.</p>Formula:C23H21N5O3SColor and Shape:SolidMolecular weight:447.51hCAII/IX-IN-1
<p>hCAII/IX-IN-1 (compound 4o) is a potent inhibitor of hCAII and hCAIX, with Ki values of 7.4 nM and 7.0 nM, respectively. It plays a significant role in cancer research.</p>Formula:C23H22N4O7S2Color and Shape:SolidMolecular weight:530.573CA inhibitor 2
<p>Compound 4H is a potent carbonic anhydrase inhibitor with an IC50 value of 0.033 μM [1].</p>Formula:C7H9N7O3S3Purity:98%Color and Shape:SolidMolecular weight:335.392-Methoxy-4-propylphenol
CAS:<p>2-Methoxy-4-propylphenol is an inhibitor of human carbonic anhydrase isoenzymes 1/2/9/12 and has antifungal activity.</p>Formula:C10H14O2Color and Shape:SolidMolecular weight:166.22hCA/VEGFR-2-IN-2
<p>Compound 8g (hCA/VEGFR-2-IN-2) is an indolinonylbenzenesulfonamide identified as a potential dual inhibitor targeting cancer-associated isozymes hCA IX/XII and</p>Formula:C23H26N6O5SPurity:98%Color and Shape:SolidMolecular weight:498.55hCAII/XII-IN-1
<p>hCAII/XII-IN-1 (compound 4l) is a potent inhibitor of hCAXII and hCAII, with Ki values of 8.4 nM and 9.4 nM, respectively. It plays a significant role in cancer research.</p>Formula:C22H20N4O6S2Color and Shape:SolidMolecular weight:500.547α-Pyrone
CAS:<p>Alpha-Pyrone exhibits inhibitory activity against tyrosinase, carbonic anhydrase 1, and carbonic anhydrase 9</p>Formula:C5H4O2Color and Shape:SolidMolecular weight:96.08Carbonic anhydrase inhibitor 15
<p>Carbonic Anhydrase Inhibitor 15 (Compound 8), with an inhibitory constant (K_i) of 8.5 nM for hCA II, exhibits analgesic effects [1].</p>Formula:C27H33N5O2S2Purity:98%Color and Shape:SolidMolecular weight:523.71α-Glycosidase-IN-2
<p>α-Glycosidase-IN-2 (compound 8b) is an inhibitor of α-glycosidase, displaying Ki values of 74.16 nM and 6.09 nM for aldose reductase and α-glycosidase, respectively. This compound is utilized in research related to diabetes.</p>Formula:C25H22N6OS2Color and Shape:SolidMolecular weight:486.61hCAI/II/IV-IN-28
CAS:<p>hCAI/II/IV-IN-28(WAY-638358) is a potent carbonic anhydrase inhibitor with potential anticonvulsant activity.</p>Formula:C14H15N3O3SPurity:96.48%Color and Shape:SolidMolecular weight:305.35hCAXII-IN-7
<p>hCAXII-IN-7 (compound 6e) functions as an inhibitor of human carbonic anhydrase XII (hCA XII) and possesses blood-brain barrier (BBB) permeability.</p>Formula:C26H25N5O6S2Purity:98%Color and Shape:SolidMolecular weight:567.64hCAII-IN-7
<p>hCAII-IN-7 (R-13) inhibits human CA I, II, IV, IX with K i of 60.7, 320.7, 2298, 35.2 nM respectively.</p>Formula:C20H25N3O4SColor and Shape:SolidMolecular weight:403.5hCAIX/VII-IN-1
<p>hCAIX/VII-IN-1 is a selective inhibitor of human carbonic anhydrase isoforms VII and IX.</p>Formula:C16H13BFN3O3Purity:98%Color and Shape:SolidMolecular weight:325.1CAIX Inhibitor S4
CAS:<p>CAIX Inhibitor S4 (S4) is an effective inhibitor of carbonic anhydrase IX/XII with a Ki of 7 nM and 2 nM, respectively.</p>Formula:C15H17N3O4SPurity:99.07%Color and Shape:SolidMolecular weight:335.38hCA/VEGFR-2-IN-1
<p>hCA/VEGFR-2-IN-1 (compound 13a) is a potent dual inhibitor targeting both Carbonic Anhydrase (CA) IX/XII and Vascular Endothelial Growth Factor Receptor 2 (</p>Formula:C21H17FN6O3SPurity:98%Color and Shape:SolidMolecular weight:452.465,6-Dihydro-2H-pyran-2-one
CAS:<p>5,6-Dihydro-2H-pyran-2-one is a carbonic anhydrase 1/9 inhibitor that inhibits KB cell viability.</p>Formula:C5H6O2Color and Shape:SolidMolecular weight:98.1hCAII-IN-6
<p>"hCAII-IN-6 (S-13) inhibits hCA II (4.4 nM) and isoforms I, IV, IX (9.2, 480.2, 14.7 nM). For glaucoma research."</p>Formula:C20H25N3O4SColor and Shape:SolidMolecular weight:403.5hCAIX/XII-IN-7
<p>Compound 3e (hCAIX/XII-IN-7) is a potent inhibitor of human carbonic anhydrase (hCA) isozymes IX and XII, displaying inhibitory constants (Kis) of 503.7 nM for</p>Formula:C17H14N6O3SPurity:98%Color and Shape:SolidMolecular weight:382.4hCA/VEGFR-2-IN-4
<p>hCA/VEGFR-2-IN-4 (compound 15b), an indolinylbenzenesulfonamide, serves as a potential dual inhibitor targeting cancer-related human carbonic anhydrases hCA IX/</p>Formula:C22H23FN6O5SPurity:98%Color and Shape:SolidMolecular weight:502.52Pyrocatechol
CAS:<p>Pyrocatechol, often known as catechol or benzene-1,2-diol, is a benzenediol, Pyrocatechol was produced at a large scale industrially, mainly as precursors to pesticides, flavors, and fragrances. Its sulfonic acid is often present in the urine of many mammals.</p>Formula:C6H6O2Color and Shape:SolidMolecular weight:110.11TSPO/Carbonic Anhydrase Modulator 1
<p>TSPO/Carbonic Anhydrase Modulator 1 (Compound 3) acts as a dual modulator of mitochondrial translocator protein and carbonic anhydrase, with a TSPOKi of 1.340 μM and a CAVII KA of 10.7 μM. It enhances neurosteroid production, increases BDNF gene expression, and demonstrates neuroprotective activity.</p>Formula:C35H51N3O3Color and Shape:SolidMolecular weight:561.798hCAIX/XII-IN-14
<p>hCAIX/XII-IN-14 (Compound 1i) is an inhibitor of hCAIX and hCAXII, with Ki values of 9.4 nM for hCAII, 5.6 nM for hCAIX, and 6.3 nM for hCAXII.</p>Formula:C16H14F3N3O4SColor and Shape:SolidMolecular weight:401.36Dorzolamide
CAS:<p>Dorzolamide is an anti-glaucoma agent and is a carbonic anhydrase inhibitor.</p>Formula:C10H16N2O4S3Purity:98%Color and Shape:White Or Almost White Crystalline PowderMolecular weight:324.44Carbonic anhydrase inhibitor 32
<p>Carbonic anhydrase inhibitor32 (compound 5B) is an orally active, selective inhibitor of hCA (carbonic anhydrase) II/VII, with Ki values of 6.3 nM for hCA II, 10.1 nM for hCA VII, and 681 nM for hCA I. It shows potential for neuroprotection and anticonvulsant effects by reducing mTOR activation and increasing hippocampal KCC2 levels.</p>Formula:C17H16N6O3SColor and Shape:SolidMolecular weight:384.41(E)-Dehydrodiconiferyl alcohol
CAS:<p>(E)-Dehydrodiconiferyl alcohol inhibits hCA IX/XII enzymes and blocks NF-κB nuclear translocation in healing tissues.</p>Formula:C20H22O6Color and Shape:SolidMolecular weight:358.39Carbonic anhydrase inhibitor 31
<p>Carbonic anhydrase inhibitor31 is an mtCA2 inhibitor (Ki: 5.2 nM) that can be used in antituberculosis research.</p>Formula:C24H20N6O5SColor and Shape:SolidMolecular weight:504.12159hCAIX-IN-17
<p>hCA IX-IN-1 inhibits hCA I/II/IX/XII with Ki of 331.4/28.4/9.4/17.8 nM, has anticancer properties.</p>Formula:C19H18N2O3SColor and Shape:SolidMolecular weight:354.42VM4-037
CAS:<p>VM4-037 is a PET imaging agent used for carbonic anhydrase IX.</p>Formula:C26H29FN6O7S2Color and Shape:SolidMolecular weight:620.67hCA/Wnt/β-catenin-IN-1
<p>hCA/Wnt/β-catenin-IN-1 (Compd 15) serves as an inhibitor with selective affinity for hCA isoforms II, IX, and XII, exhibiting K i values of 33.6, 24.1, and 6.8</p>Color and Shape:Odour SolidCarbonic anhydrase inhibitor 29
<p>Carbonic anhydrase inhibitor29 (Compound 5d) is an inhibitor targeting carbonic anhydrase IX and XII, with an inhibition constant (Ki) of 26.6 nM for carbonic anhydrase IX and a Ki of 10.9 nM for carbonic anhydrase XII. Carbonic anhydrase inhibitor29 can be used in cancer research.</p>Color and Shape:Odour SolidCAXII-IN-2
<p>CAXII-IN-2 (compound 3j) is a highly effective inhibitor of CAXII. It demonstrates inhibitory activity against CA IX and CAXII, with Ki values of 27.4 nM and 4.0 nM, respectively.</p>Formula:C16H13FNO4PColor and Shape:SolidMolecular weight:333.05662hCAII-IN-8
CAS:<p>Compound CDy9 is a highly selective inhibitor of carbonic anhydrase (CA) with an IC50 value of 0.18 μM for hCA II.</p>Formula:C15H16N2O5SPurity:99.73%Color and Shape:SoildMolecular weight:336.36hCAI/II-IN-10
<p>hCAI/II-IN-10 (Compound 5d) is an inhibitor of human carbonic anhydrase I and II (hCA I and hCA II), with IC50 values of 4.32 nM and 3.89 nM, respectively.</p>Formula:C24H17Cl2N3O3S2Color and Shape:SolidMolecular weight:530.446DPP IV/hCA II-IN-1
CAS:<p>DPP IV/hCA II-IN-1: strong DPP IV & CA inhibitor, IC50=0.049μM (DPP IV), Ki=0.0361-3.034μM (CA II-IV).</p>Formula:C17H20N2O5SColor and Shape:SolidMolecular weight:364.42Bendroflumethiazide
CAS:<p>Bendroflumethiazide (Naturetin) is a thiazide diuretic with actions and uses similar to those of HYDROCHLOROTHIAZIDE. It has been used in the treatment of familial hyperkalemia, hypertension, edema, and urinary tract disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p810)</p>Formula:C15H14F3N3O4S2Purity:98% - >99.99%Color and Shape:Crystals From Dioxane SolidMolecular weight:421.41Carbonic anhydrase
CAS:<p>Carbonic anhydrase, a zinc enzyme in all life forms, converts CO2 to bicarbonate; studied for cancer, glaucoma, obesity, epilepsy.</p>Color and Shape:SolidCarbonic anhydrase inhibitor 26
<p>Compound 6T, designated as Carbonic anhydrase inhibitor26, acts as an inhibitor of Carbonic Anhydrase II (Carbonic AnhydraseII), exhibiting an IC50 value of 9.10 ± 0.26 μM.</p>Formula:C17H14N6O4Color and Shape:SolidMolecular weight:366.33AV22-149
<p>AV22-149 (compound 22) is an inhibitor of Carbonic Anhydrase .</p>Formula:C23H28F3N3O6S2Color and Shape:SolidMolecular weight:563.61DOTA-XYIMSR-01
CAS:<p>DOTA-XYIMSR-01 is a molecular probe targeting CAIX, capable of being labeled with 177Lu for the treatment and localization of malignant gliomas. The uptake of [177Lu]Lu-XYIMSR-01 in U87MG tumors is 6.19% injected dose per gram (% ID/g), with a tumor-to-muscle uptake ratio of 20.14. In an orthotopic glioma model, co-administration with temozolomide significantly enhances survival rates and inhibits tumor growth in mice. DOTA-XYIMSR-01 shows potential for research in the field of cancer treatment.</p>Formula:C61H88N16O22S2Color and Shape:SolidMolecular weight:1461.57Acesulfame
CAS:<p>Acesulfame inhibits CA9/12 and can be used to study inflammation-related diseases.</p>Formula:C4H5NO4SColor and Shape:SolidMolecular weight:163.15Carbonic anhydrase inhibitor 18
<p>Carbonic anhydrase inhibitor18 (Compound 9) is an inhibitor of human carbonic anhydrase (hCA) isozymes, with Ki values of 604.8 nM for hCA I, 333.6 nM for hCA II, 1.9 nM for hCA IX, and 6.7 nM for hCA XII. Carbonic anhydrase inhibitor18 is applicable in cancer research.</p>Formula:C26H28N4O6S2Molecular weight:556.14503Girentuximab
CAS:<p>Girentuximab (G250) is an anti-carbonic anhydrase IX (CAIX) monoclonal antibody with anti-cancer activity for the study of uroepithelial carcinoma PET (ZiPUP).</p>Color and Shape:LiquidMolecular weight:145.55 kDahCAIX/XII-IN-11
<p>hCAIX/XII-IN-11 (Compound 6c) is an inhibitor of hCA IX and hCA XII, exhibiting Ki values of 0.7 μM for both isoforms. This compound is applicable in cancer research.</p>Formula:C13H10FN3O4Molecular weight:291.06553GZ22-4
<p>GZ22-4 is a near-infrared (NIR) fluorescent probe with a high affinity for carbonic anhydrase IX (CAIX), exhibiting a dissociation constant (Kd) of 0.2 nM. It is applicable in studies for visualizing CAIX-positive tumors.</p>Formula:C88H126F3N6NaO24S4Molecular weight:1858.75561SH7s
<p>SH7s is an effective carbonic anhydrase inhibitor, exhibiting Ki values of 15.9 nM for hCA IX and 55.2 nM for hCA XII. Additionally, SH7s acts as a hypoxia-mediated chemosensitizer in colorectal cancer cells.</p>Formula:C24H19ClF3N5O4SColor and Shape:SolidMolecular weight:565.95hCA XII-IN-6
<p>Compound 4d, known as hCA XII-IN-6, is a potent inhibitor of human carbonic anhydrase XII (hCA XII) with a Ki value of 84.2 nM and exhibits anti-proliferative</p>Formula:C11H9N5O3S2Purity:98%Color and Shape:SolidMolecular weight:323.35Chlorothiazide
CAS:<p>Chlorothiazide (Diuril) is a thiazide diuretic with actions and uses similar to those of HYDROCHLOROTHIAZIDE.</p>Formula:C7H6ClN3O4S2Purity:98.46% - 98.91%Color and Shape:Crystals Physical Description Crystals; White Powder (Ntp 1992)Molecular weight:295.72Carbonic Anhydrase 12 Protein, Cynomolgus, Recombinant (His)
<p>Carbonic anhydrases (CAs) are a family of enzymes involved in the pH regulation of metabolically active cells/tissues.</p>Color and Shape:Lyophilized PowderMolecular weight:32.04 kDa (predicted). Due to glycosylation, the protein migrates to 40-50 kDa based on Tris-Bis PAGE result.Acetazolamide-d3
CAS:<p>Acetazolamide D3 is a deuterium-labeled Acetazolamide. Acetazolamide is a potent carbonic anhydrase inhibitor.</p>Formula:C4H6N4O3S2Purity:98%Color and Shape:SolidMolecular weight:225.26M 12325
CAS:<p>M 12325 is used in the production of furosemide; rhinitis and occupational asthma were observed in workers from a lasamide production line.</p>Formula:C7H5Cl2NO4SColor and Shape:White To Almost White Solid PowderMolecular weight:270.09Brinzolamide hydrochloride
<p>Brinzolamide (AL-4862) HCl selectively inhibits carbonic anhydrase II, reducing IOP for glaucoma research. IC50: 3.2 nM.</p>Color and Shape:Solid4-(benzyloxy)benzene-1-sulfonamide
CAS:<p>4-(benzyloxy)benzene-1-sulfonamide is inhibitor of human recombinant CA-7.</p>Formula:C13H13NO3SPurity:97.54%Color and Shape:SolidMolecular weight:263.31Zolamide
CAS:<p>Zolamide (CL 5343) may be used to prevent altitude sickness and reduce the symptoms.</p>Formula:C2H4N4O2S2Purity:99.75%Color and Shape:SolidMolecular weight:180.21EMAC10101d
CAS:<p>compound EMAC10101d, bearing a 2,4-dichorophenyl substituent in position 4 of the dihydrothiazole ring, was the most potent and selective toward hCA II with an</p>Formula:C17H15Cl2N3O2S2Purity:99.96%Color and Shape:SolidMolecular weight:428.36Benzenesulfonamide
CAS:<p>Benzenesulfonamide (Benzosulfonamide) ia an inhibitor of carbonic anhydrases.</p>Formula:C6H7NO2SPurity:99.42% - 99.99%Color and Shape:White Crystalline PowderMolecular weight:157.19Dichlorphenamide
CAS:<p>Dichlorphenamide (Diclofenamide) is a carbonic anhydrase inhibitor that is used in the treatment of glaucoma.</p>Formula:C6H6Cl2N2O4S2Purity:96.87% - 97.25%Color and Shape:Needles From Dimethylsulfoxide + Water SolidMolecular weight:305.16Benzolamide
CAS:<p>Benzolamide (CL 11366) inhibits carbonic anhydrase effectively and low-threshold calcium currents in hippocampal pyramidal neurons.</p>Formula:C8H8N4O4S3Purity:99.31%Color and Shape:SolidMolecular weight:320.37Dichlorphenamide disodium
CAS:<p>Dichlorphenamide disodium: an oral carbonic anhydrase inhibitor that lowers eye pressure, promising for glaucoma study.</p>Formula:C6H6Cl2N2Na2O4S2Color and Shape:SolidMolecular weight:351.12Dimethylfraxetin
CAS:<p>Dimethylfraxetin (6,7,8-Trimethoxycoumarin) is a Carbonic anhydrase inhibitor(Ki：0.0097 μM)</p>Formula:C12H12O5Purity:99.96% - ≥95%Color and Shape:SolidMolecular weight:236.224-Amino-6-(trifluoromethyl)benzene-1,3-disulfonamide
CAS:<p>4-Amino-6-(trifluoromethyl)benzene-1,3-disulfonamide (4-Amino-6-(trifluoromethyl)benzene-1,3-d) is a carbonic anhydrase inhibitor, used as a potential anti-</p>Formula:C7H8F3N3O4S2Purity:98.58%Color and Shape:SolidMolecular weight:319.28Dorzolamide hydrochloride
CAS:<p>Dorzolamide hydrochloride (MK507 hydrochloride) is the hydrochloride salt form of dorzolamide, an inhibitor of carbonic anhydrase, a zinc-containing enzyme that</p>Formula:C10H17ClN2O4S3Purity:99.48% - 99.67%Color and Shape:White Off-White Crystalline PowderMolecular weight:360.9Methyclothiazide
CAS:<p>Methyclothiazide (Aquatensen) is a substituted benzothiadiazide, used to treat high blood pressure and fluid retention caused by various conditions including</p>Formula:C9H11Cl2N3O4S2Purity:99.13%Color and Shape:SolidMolecular weight:360.242,3-dihydro-1H-indene-5-sulfonamide
CAS:<p>2,3-dihydro-1H-indene-5-sulfonamide is Carbonic anhydrase 12 (human) inhibitor.</p>Formula:C9H11NO2SPurity:99.89%Color and Shape:SolidMolecular weight:197.25Orthanilamide
CAS:<p>Orthanilamide (Orthanilamide) is a molecule containing the sulfonamide functional group attached to an aniline.</p>Formula:C6H8N2O2SPurity:99.72% - 99.96%Color and Shape:White To Pale Cream Crystalline Powder Or CrystalsMolecular weight:172.2Indisulam
CAS:<p>Indisulam (E 7070) is a dual-action anticancer drug, blocking G1/S cell cycle transition by degrading cyclin E and activating p53/p21.</p>Formula:C14H12ClN3O4S2Purity:98.68% - 99.77%Color and Shape:SolidMolecular weight:385.85U-104
CAS:<p>U-104 (NSC-213841) is an effective carbonic anhydrase (CA) inhibitor for CA IX( Ki=45.1 nM) and CA XII(Ki=4.5 nM).</p>Formula:C13H12FN3O3SPurity:98.76% - 99.88%Color and Shape:SolidMolecular weight:309.32Ethoxzolamide
CAS:<p>Ethoxzolamide (L-643786) is a carbonic anhydrase inhibitor.</p>Formula:C9H10N2O3S2Purity:98.27% - 99.62%Color and Shape:Crystals From Ethyl Acetate + Skellysolve B SolidMolecular weight:258.32Polmacoxib
CAS:<p>Polmacoxib, a first-class NSAID, dual inhibitor of CA and COX-2, may hinder colorectal cancer growth in mice.</p>Formula:C18H16FNO4SPurity:97.88%Color and Shape:SolidMolecular weight:361.39Fluorometholone Acetate
CAS:<p>Fluorometholone Acetate (Oxylone acetate) is a synthetic corticosteroid, used in the treatment of steroid responsive inflammatory conditions of the eye.</p>Formula:C24H31FO5Purity:99.76%Color and Shape:SolidMolecular weight:418.50GV2-20
CAS:<p>GV2-20 is an effective carbonic anhydrase 2 inhibitors.</p>Formula:C15H13N3O6Purity:98%Color and Shape:SolidMolecular weight:331.28Disulfamide
CAS:<p>Disulfamide: Oral carbonic anhydrase inhibitor, IC50 0.07 μM, diuretic by blocking Na+/HCO3- reabsorption.</p>Formula:C7H9ClN2O4S2Purity:98.1%Color and Shape:SolidMolecular weight:284.74HCAIX-IN-2
CAS:<p>HCAIX-IN-2 (compound 9d) is a selective inhibitor of carbonic anhydrase and acts on hCA IX (Ki: 24.6 nM) and hCA XII (Ki: 45.3 nM).</p>Formula:C19H16N8O4SColor and Shape:SolidMolecular weight:452.45hCAIX-IN-11
CAS:<p>hCAIX-IN-11 inhibits carbonic anhydrases IX & XII with Ki of 32.7 nM & 623.5 nM, respectively.</p>Formula:C21H15ClN4O3Color and Shape:SolidMolecular weight:406.82hCAI/II-IN-1
CAS:<p>hCAI/II-IN-1 (Compound 3h) is a human carbonic anhydrase I and II (hCA I/II) inhibitor that acts on hCA I (IC50: 0.047 μM) and hCA II (IC50: 0.024 μM).</p>Formula:C18H29N5O3S3Color and Shape:SolidMolecular weight:459.65hCAIX/XII-IN-2
CAS:<p>Compound 6a: Selective hCAIX/XII inhibitor; Ki: 30 nM (hCAIX), 3.6 nM (hCAXII); >10,000 nM (hCAI/II).</p>Formula:C19H14N2O4Color and Shape:SolidMolecular weight:334.33CDK2-IN-12
CAS:<p>CDK2-IN-12 (10b), potent CDK2 inhibitor, IC50: 11.6 μM; inhibits hCA I/II/IX/XII, KI: 3534/638.4/44.3/48.8 nM; anti-cancer properties.</p>Formula:C20H17N9O2SColor and Shape:SolidMolecular weight:447.47Clofenamide
CAS:<p>Clofenamide is a low-ceiling sulfonamide diuretic.</p>Formula:C6H7ClN2O4S2Color and Shape:SolidMolecular weight:270.71hCAII-IN-2
CAS:<p>hCAII-IN-2 inhibits human carbonic anhydrases I, II, IX, XII with Ki values of 261.4, 3.8, 19.6, 45.2 nM respectively.</p>Formula:C25H18ClN5O4SColor and Shape:SolidMolecular weight:519.96hCAIX/XII-IN-3
CAS:<p>Compound 6q inhibits hCAIX/CAXII; K i : hCAI >10000 nM, hCAII >10000 nM, hCAIX 66.2 nM, hCAXII 4.4 nM.</p>Formula:C20H13F3N2O4Color and Shape:SolidMolecular weight:402.32CDK2-IN-11
CAS:<p>CDK2-IN-11 inhibits CDK2 (IC50: 6.4 μM) and targets hCA II, IX, XII (Ki: 23.4-56.3 nM); suited for cancer research.</p>Formula:C18H14ClN7O2SColor and Shape:SolidMolecular weight:427.87hCA I-IN-1
CAS:<p>hCA I-IN-1 inhibits hCA I (Ki: 38.3 nM), II (Ki: 716.4 nM), IX (Ki: 940.1 nM), XII (Ki: 192.8 nM).</p>Formula:C27H23N5O4SColor and Shape:SolidMolecular weight:513.57hCAXII-IN-3
CAS:<p>hCAXII-IN-3 (Compound 6o) is a selective inhibitor of human carbonic anhydrase XII (hCAXII) (Ki: 10.0 nM).</p>Formula:C26H20BrN5O3SColor and Shape:SolidMolecular weight:562.44Carbonic anhydrase inhibitor 14
CAS:<p>CA inhibitor 14 blocks hCA I/II/IX/XII (K i of 1203/99.7/9.4/27.7 nM) and CDK2 (IC50: 20.3 μM), showing antitumor effects.</p>Formula:C18H17N7O2SColor and Shape:SolidMolecular weight:395.44
