GluR
Glutamate Receptor inhibitors are compounds that block the activity of glutamate receptors, which are the main excitatory neurotransmitter receptors in the brain. These receptors play a pivotal role in synaptic transmission, plasticity, learning, and memory. Dysregulation of glutamate signaling is associated with various neurological disorders, including epilepsy, stroke, and neurodegenerative diseases. GluR inhibitors are essential for investigating the mechanisms of excitotoxicity and developing neuroprotective strategies. At CymitQuimica, we offer a range of glutamate receptor inhibitors to support your research in synaptic function, neuroprotection, and cognitive disorders.
Found 265 products of "GluR"
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Piracetam
CAS:Piracetam (UCB-6215), a cyclic derivative of the neurotransmitter gamma-aminobutyric acid (GABA), is used in therapy of the extensive cognitive disorders.Formula:C6H10N2O2Purity:97.16%Color and Shape:Crystals From Isopropanol SolidMolecular weight:142.16NBQX disodium
CAS:NBQX Disodium (FG9202 disodium) is a highly selective, competitive AMPA receptor antagonist with neuroprotective and anticonvulsant activity.Formula:C12H6N4Na2O6SPurity:97.32% - 97.6%Color and Shape:SolidMolecular weight:380.2415(R)-3,4-DCPG HCl
(R)-3,4-DCPG HCl is a potent and selective mGlu8a receptor agonist that activates metabotropic glutamate receptors on primary afferent terminals in the neonatalFormula:C10H10ClNO6Purity:99.74% - 99.83%Color and Shape:SoildMolecular weight:275.64(R)-ADX-47273
CAS:(R)-ADX-47273 is a potent mGluR5 positive allosteric modulator(EC50 of 168 nM for potentiation ).Formula:C20H17F2N3O2Purity:99.87%Color and Shape:SolidMolecular weight:369.36Ref: TM-T13441
2mg39.00€5mg62.00€1mL*10mM (DMSO)67.00€10mg88.00€25mg161.00€50mg245.00€100mg370.00€200mg515.00€Org-26576
CAS:Org-26576 is a positive allosteric modulator of the AMPA receptor.Formula:C11H12N2O2Purity:99.67%Color and Shape:SolidMolecular weight:204.23LY339434 HCl
LY339434 HCl is a low affinity GluR5 erythrocyte receptor agonist.LY339434 HCl causes rapid neuronal death primarily by affecting N-methyl-D-aspartate (NMDA)Formula:C18H20ClNO4Purity:97.10% - 97.19%Color and Shape:SoildMolecular weight:349.81Decoglurant
CAS:Decoglurant (RO4995819) is a negative allosteric modulator of mGluR2 and mGluR3 and it also is developed as an antidepressant.Formula:C21H11F6N5Purity:99.77%Color and Shape:SolidMolecular weight:447.34Ref: TM-T15090
1mg52.00€5mg111.00€1mL*10mM (DMSO)152.00€10mg164.00€25mg294.00€50mg411.00€100mg572.00€200mg772.00€Basimglurant
CAS:Basimglurant (CTEP Derivative) is a potent, selective and orally available modulator of mGlu5 negative allosteric(Kd of 1.1 nM).Formula:C18H13ClFN3Purity:98.35%Color and Shape:SolidMolecular weight:325.77Ref: TM-T12717
1mg71.00€5mg152.00€1mL*10mM (DMSO)167.00€10mg222.00€25mg358.00€50mg532.00€100mg665.00€200mg898.00€DHPG
CAS:DHPG is a potent Group I mGluR agonist; doesn't affect Group II/III; linked to phospholipase D.Formula:C8H9NO4Purity:99.55%Color and Shape:SolidMolecular weight:183.16γ-DGG acetate(6729-55-1 free base)
CAS:gamma-DGG acetate(6729-55-1 free base) (γ-D-Glutamylglycine) is a competitive blocker of AMPA receptor.Formula:C9H16N2O7Purity:99.81%Color and Shape:SolidMolecular weight:264.23AZD-8529 mesylate
CAS:AZD-8529 mesylate is a highly selective, and orally bioavailable positive allosteric modulator of mGluR2 (EC50: 285 nM).Formula:C25H28F3N5O6SPurity:99.19%Color and Shape:SolidMolecular weight:583.58KM02894
CAS:KM02894 inhibits glutamate release, potentially reducing cancer-induced bone pain in tumor studies.Formula:C7H9N3OS2Purity:99.98%Color and Shape:SolidMolecular weight:215.3VU0650786
CAS:VU0650786: selective mGlu3 NAM, CNS-penetrant, IC50 392 nM, shows antidepressant/anxiolytic effects in rodents.Formula:C18H15ClFN5O2Purity:99.09%Color and Shape:SolidMolecular weight:387.8Ref: TM-T13318
1mg90.00€5mg222.00€1mL*10mM (DMSO)245.00€10mg313.00€25mg530.00€50mg757.00€100mg1,044.00€MMPIP hydrochloride
CAS:MMPIP hydrochloride is a selective antagonist of allosteric mGluR7.Formula:C19H16ClN3O3Purity:99.88%Color and Shape:SolidMolecular weight:369.8Ref: TM-T23008L
1mg56.00€5mg119.00€1mL*10mM (DMSO)133.00€10mg192.00€25mg394.00€50mg585.00€100mg833.00€200mg1,134.00€Pomaglumetad methionil anhydrous
CAS:LY2140023, potential schizophrenia treatment, is an oral prodrug of LY404039, a selective mGlu2/3 agonist.Formula:C12H18N2O7S2Purity:98%Color and Shape:SolidMolecular weight:366.41GYKI-47261 dihydrochloride
CAS:GYKI-47261 dihydrochloride is an AMPA receptor antagonist and CYP2E1 inducer, demonstrating broad-spectrum anticonvulsant and neuroprotective activities.Formula:C18H17Cl3N4Purity:98.32% - 99.14%Color and Shape:SolidMolecular weight:395.71(±)-LY367385
CAS:(±)-LY367385 is the racemic form of LY367385, and LY367385 is a highly potent and selective mGluR1a antagonist.Formula:C10H11NO4Color and Shape:SolidMolecular weight:209.201STX-107
CAS:STX-107 is a potent and selective mGluR5 agonist for the study of Fragile X Syndrome.Formula:C18H10FN3SPurity:99.17%Color and Shape:SolidMolecular weight:319.36MGS0028
CAS:MGS0028 is a selective agonist of metabotropic glutamate 2/3 receptor, it could reverse abnormal behaviors in mice induced by isolation rearing.Formula:C8H8FNO5Color and Shape:SolidMolecular weight:217.15MPPG
CAS:MPPG is a selective L-AP4-sensitive receptor antagonist (kD=9.2 μM).Formula:C9H12NO5PColor and Shape:SolidMolecular weight:245.171LY2812223
CAS:LY2812223: selective mGlu2 agonist; binds mGlu2/mGlu3 (Ki=144/156 nM).Formula:C10H12N4O4SPurity:98%Color and Shape:SolidMolecular weight:284.29VU0483605
CAS:VU0483605 is an effective and selective positive allosteric modulator of mGluR1 with EC50s of 390 and 356 nM for human and rat, respectively.
Formula:C20H10Cl3N3O3Purity:99.61%Color and Shape:SolidMolecular weight:446.67(S,S)-BMS-984923
CAS:(S,S)-BMS-984923 is a weak mGluR5 modulator with EC50 >1μM; less active than its potent counterpart.Formula:C22H15ClN2O2Color and Shape:SolidMolecular weight:374.82(S)-3,4-DCPG HCl
(S)-3,4-DCPG HCl is a selective mGluR8a agonist, impacting AV12-664 cells with an EC50 of 31 nM.Formula:C10H10ClNO6Purity:99.53% - 99.86%Color and Shape:SoildMolecular weight:275.64Ref: TM-T23288L
1mg173.00€1mL*10mM (DMSO)394.00€5mg437.00€10mg625.00€25mg982.00€50mg1,341.00€100mg1,773.00€500mg3,565.00€(S)-3,4-DCPG
CAS:(S)-3,4-DCPG ((S)-3,4-Dicarboxyphenylglycine) is a selective agonist of human metabotropic glutamate receptor 8a (mGluR8a).Formula:C10H9NO6Purity:98%Color and Shape:SolidMolecular weight:239.18mGluR3 modulator-1
CAS:1-ethyl-3-morpholin-4-yl tetrahydroisoquinoline: mGluR3 modulator, potential for Parkinson's.Formula:C16H21N3OPurity:98.99%Color and Shape:SolidMolecular weight:271.36MGS0274
CAS:MGS0274, a lipophilic prodrug of mGlu2/3 agonist MGS0008, enhances oral bioavailability, potentially aiding schizophrenia research.Formula:C21H32FNO7Color and Shape:SolidMolecular weight:429.485ML353
ML353 activates TREK-1/2, binds mGlu5 SAM (Ki=18.2 nM), surpasses 5mpep, may address SAM activity/blocking.Formula:C19H15FN2OPurity:99.98% - 99.98%Color and Shape:SoildMolecular weight:306.33Ref: TM-T67917
5mg50.00€1mL*10mM (DMSO)50.00€10mg74.00€25mg114.00€50mg156.00€100mg219.00€200mg298.00€KRP-199 sodium
KRP-199 sodium sodium is highly potent and selective for AMPA-R in vitro and exhibits good neuroprotection in vivo.Formula:C22H12F3N5Na2O7Purity:97.27%Color and Shape:SoildMolecular weight:561.33(S)-AMPA HCl
(S)-AMPA HCl (L-AMPA HCl) is a selective AMPA receptor agonist with potential antidepressant activity. It can be used in research on Parkinson's disease.Formula:C7H11ClN2O4Purity:99.18%Color and Shape:SolidMolecular weight:222.63LY3020371
CAS:LY3020371: potent, selective mGlu 2/3 receptor antagonist with Ki of 5.26 nM (hmGluR2) and 2.50 nM (hmGluR3); key in depression studies.Formula:C15H15F2NO5SColor and Shape:SolidMolecular weight:359.341H-Pyrrolo[2,1-c][1,2,4]benzothiadiazine, 2,3,3a,4-tetrahydro-, 5,5-dioxide, (3aR)-
CAS:1H-Pyrrolo[2,1-c][1,2,4]benzothiadiazine, 2,3,3a,4-tetrahydro-, 5,5-dioxide, (3aR)- is a low activity isomer of S 18986.Formula:C10H12N2O2SPurity:99.96%Color and Shape:SoildMolecular weight:224.28L-AP3
CAS:L-AP3 blocks mGluR, inhibits D/L-phosphoserine (IC50: 368/2087 μM).Formula:C3H8NO5PColor and Shape:White Hygroscopic SolidMolecular weight:169.073JF-NP-26
Releases pain-blocking raseglurant under 405 nm light. Inhibits Quisqualate. Analgesic in vivo. Quantum yield: 0.18.Color and Shape:SolidDD205-291
CAS:DD205-291 is an orally active PROTAC HPK1 degrader with a DC50 of 5.3 nM. It inhibits SLP-76 phosphorylation and induces IL-2 and IFN-γ.Formula:C38H38ClF3N10O3Color and Shape:SolidMolecular weight:775.22LY3027788
CAS:LY3027788, potent oral prodrug of LY3020371, is a strong mGlu2/3 antagonist with notable antidepressant effects.Formula:C25H31F2NO11SColor and Shape:SolidMolecular weight:591.58LY3027788 hydrochloride
CAS:LY3027788 HCl, potent oral prodrug of LY3020371, targets mGlu2/3 with antidepressant effects.Formula:C25H32ClF2NO11SColor and Shape:SolidMolecular weight:628.03mGluR5 modulator 1
CAS:mGluR5 modulator 1 is a positive modulator for mGluR5, used in schizophrenia and cognitive research.Formula:C18H19ClFN3O2Color and Shape:SolidMolecular weight:363.82NS-102
CAS:NS-102 is a glutamate receptor and NMDA receptor antagonist that inhibits erythrocyanine (GluK2) and inhibits specific binding to the glur6 receptor.Formula:C12H11N3O4Purity:98.48% - 98.95%Color and Shape:SolidMolecular weight:261.23VU0422288
CAS:VU0422288 (ML396) is a type III mGlu receptor (mGlus) orthosteric modulator with inhibitory effects on mGluR4.VU0422288 can be used to study Rett syndrome.Formula:C17H11Cl2N3O2Purity:99.77%Color and Shape:SolidMolecular weight:360.19LY487379
CAS:LY487379: human mGluR2 PAM, boosts glutamate binding, aids cognitive flexibility, may treat schizophrenia. EC50: 1.7 μM (mGlu2), >10 μM (mGlu3).Formula:C21H19F3N2O4SColor and Shape:SolidMolecular weight:452.45GYKI 53655 hydrochloride
CAS:GYKI 53655 hydrochloride (LY300168 hydrochloride) is an antagonist of AMPA and is used in the study of neurological disorders.Formula:C19H21ClN4O3Purity:98.02%Color and Shape:SolidMolecular weight:388.85Ro 01-6128
CAS:Positive allosteric modulator of mGlu1 receptorsFormula:C17H17NO3Purity:98%Color and Shape:SolidMolecular weight:283.32VU0364770 hydrochloride
CAS:VU0364770 hydrochloride: potent, selective mGlu4 PAM; EC50=290 nM (rat), 1.1 μM (human).Formula:C12H10Cl2N2OPurity:98%Color and Shape:SolidMolecular weight:269.13EGLU
CAS:EGLU, an antidepressant and potent mGluR-2 antagonist, binds with a 66 μM Kd to (lS,3S)-ACPD sites.Formula:C7H13NO4Purity:99.98%Color and Shape:SolidMolecular weight:175.18γ-DGG
CAS:gamma-DGG is a competitive blocker of AMPA receptor.Formula:C7H12N2O5Purity:98%Color and Shape:SolidMolecular weight:204.18JNJ-46778212
CAS:JNJ-46778212 (VU 0409551) is a selective and potent mGlu5 allosteric modulator (EC50: 260 nM) for the study of neurodissection.Formula:C20H17FN2O3Purity:99.24%Color and Shape:SolidMolecular weight:352.36LY341495
CAS:LY341495 is a potent metabotropic glutamate receptor antagonist and can be used to study neurological disorders.Formula:C20H19NO5Purity:98.53% - 99.37%Color and Shape:SolidMolecular weight:353.37AMN082
CAS:AMN082 is an mGluR7 agonist with antidepressant effects. Neuroprotective effect of AMN082 on neuronal apoptosis in rats with traumatic brain injury.Formula:C28H30Cl2N2Purity:97.13% - 98.63%Color and Shape:SolidMolecular weight:465.46GYKI 52466 dihydrochloride
CAS:GYKI 52466 dihydrochloride is an AMPA/Kainate receptor antagonist with anticonvulsant activity and can be used to study neurological diseases.Formula:C17H17Cl2N3O2Purity:99.38%Color and Shape:SolidMolecular weight:366.24E4CPG
CAS:E4CPG is a novel group I/II metabotropic glutamate receptor antagonist, more potent than (RS)-MCPG.Formula:C11H13NO4Purity:99.96%Color and Shape:SolidMolecular weight:223.23(S)-ATPO
CAS:(S)-ATPO is Competitive antagonist at GluR1-4 (AMPA-preferring) receptors.
Formula:C11H19N2O7PPurity:98.37% - 99.41%Color and Shape:SolidMolecular weight:322.25(RS)-3-Hydroxyphenylglycine
CAS:(RS)-3-Hydroxyphenylglycine is a PI-linked metabotropic glutamate receptors agonist.Formula:C8H9NO3Purity:99.29%Color and Shape:SolidMolecular weight:167.16VU-29
CAS:VU-29 is a positive allosteric mGlu5 receptor modulator with EC50=9 nM and Ki=244 nM for rmGluR5. It is selective for mGluR5 relative to other mGluR subtypes.Formula:C22H16N4O3Purity:99.63%Color and Shape:SolidMolecular weight:384.39Ref: TM-T23515
2mg33.00€5mg50.00€1mL*10mM (DMSO)55.00€10mg86.00€25mg161.00€50mg259.00€100mg371.00€200mg530.00€Chelidamic acid
CAS:Chelidamic acid is a heterocyclic organic acid with a pyran skeleton. Chelidamic acid is inhibitors of glutamate decarboxylase, with a Ki of 33 μM.Formula:C7H5NO5Purity:98.11%Color and Shape:Pale Yellow PowderMolecular weight:183.12PHCCC
CAS:PHCCC is a Group I mGluR antagonist and enhances mGluR4 function; also blocks mGluR2/8.Formula:C17H14N2O3Purity:>99.99%Color and Shape:SolidMolecular weight:294.3DNQX
CAS:DNQX (FG 9041) is a competitive, non-NMDA glutamate receptor antagonist (IC50s = 0.5 and 0.1 μM for AMPA and kainate receptors, respectively)
Formula:C8H4N4O6Purity:97.27% - 99.1%Color and Shape:Off-White Powder With A Yellow TingeMolecular weight:252.14JNJ16259685
CAS:JNJ16259685 (TN.T 16259685) is a selective mGluR1 antagonist, and inhibits the synaptic activation of mGluR1 in a concentration-dependent manner with IC50 of 19Formula:C20H23NO3Purity:98.31%Color and Shape:SolidMolecular weight:325.4Ref: TM-T5512
1mg46.00€2mg62.00€5mg95.00€1mL*10mM (DMSO)95.00€10mg133.00€25mg278.00€50mg424.00€100mg620.00€VU0361737
CAS:VU0361737 (ML-128) is a mGlu4 PAM; EC50 is 240 nM (human) and 110 nM (rat), weak at mGlu5/8, inactive at mGlu1/2/3/6/7, CNS-penetrant.Formula:C13H11ClN2O2Purity:99.60% - 99.85%Color and Shape:SolidMolecular weight:262.69FTIDC
CAS:FTIDC: potent, selective mGluR1 allosteric antagonist, weak on mGluR5. IC50: human 5.8 nM, mouse 3.1 nM. Noncompetitive.Formula:C18H23FN6OPurity:94.58%Color and Shape:SolidMolecular weight:358.41Ref: TM-T3483
1mg100.00€2mg145.00€5mg215.00€1mL*10mM (DMSO)236.00€10mg340.00€25mg565.00€50mg797.00€100mg1,071.00€CFMTI
CAS:CFMTI: potent mGluR1 allosteric antagonist, 2000x selectivity over mGluR5, IC50: 2.6 nM.Formula:C19H16FN5OPurity:97.23%Color and Shape:SolidMolecular weight:349.36Ref: TM-T3482
1mg57.00€2mg82.00€5mg120.00€1mL*10mM (DMSO)133.00€10mg170.00€25mg304.00€50mg432.00€100mg602.00€Farampator
CAS:Farampator (CX-691) (CX-691;Org24448) is a positive modulator of AMPA receptor.Formula:C12H13N3O2Purity:99.84% - >99.99%Color and Shape:SolidMolecular weight:231.25CX614
CAS:CX614 is a positive allosteric modulator of the AMPA receptor concerning AMPA.Formula:C13H13NO4Purity:97.37%Color and Shape:SolidMolecular weight:247.25Ref: TM-T19698
5mg52.00€1mL*10mM (DMSO)55.00€10mg78.00€25mg119.00€50mg172.00€100mg259.00€200mg388.00€ADX-47273
CAS:ADX-47273 (BA 94673139) is a positive and selective allosteric modulator for the metabotropic glutamate receptor subtype mGluR5(EC50=170 nM).Formula:C20H17F2N3O2Purity:97% - 99.22%Color and Shape:SolidMolecular weight:369.36ADX88178
CAS:ADX88178 is a potent positive allosteric modulator for metabotropic glutamate receptor 4 (mGluR4) with EC50 of 4 nM for human mGluR4.Formula:C12H12N6SPurity:99.55%Color and Shape:SolidMolecular weight:272.33AZD-8529
CAS:AZD-8529: selective, oral mGluR2 modulator, EC50 285 nM; inactive on mGluR1,3-8 at 20-25 M.Formula:C24H24F3N5O3Color and Shape:SolidMolecular weight:487.47XAP044
CAS:XAP044 blocks mGlu7, inhibiting long-term potentiation in mouse brain with a half-maximal effect at 88nm.Formula:C15H9IO4Purity:97.41%Color and Shape:SolidMolecular weight:380.13Ref: TM-T21995
1mg58.00€2mg82.00€5mg107.00€1mL*10mM (DMSO)146.00€10mg197.00€25mg350.00€50mg528.00€100mg755.00€NBQX
CAS:NBQX (FG9202) is a potent, selective and competitive AMPA receptor antagonist. Neuroprotective and anticonvulsant; active in vivo.Formula:C12H8N4O6SPurity:97.66% - 99.93%Color and Shape:SolidMolecular weight:336.28Ref: TM-T4113
1mg38.00€2mg50.00€5mg84.00€1mL*10mM (DMSO)92.00€10mg114.00€25mg222.00€50mg334.00€100mg497.00€200mg717.00€pep2-EVKI acetate(1315378-67-6 free base)
Pep2-EVKI acetate, a cell-permeable peptide, disrupts PICK1-GluR2 AMPA receptor binding.Formula:C64H99N13O21Purity:97.63%Color and Shape:SolidMolecular weight:1386.55(RS)-MCPG
CAS:(RS)-MCPG ((±)-MCPG) is a non-selective group I/II metabotropic glutamate receptor antagonist.Formula:C10H11NO4Purity:99.96%Color and Shape:SolidMolecular weight:209.2Ro 67-7476
CAS:Ro 67-7476 is a positive allosteric modulator of mGlu1 receptors.Formula:C17H18FNO2SPurity:99.69%Color and Shape:SolidMolecular weight:319.39Ref: TM-T3478
1mg34.00€2mg48.00€1mL*10mM (DMSO)78.00€5mg88.00€10mg124.00€25mg244.00€50mg442.00€100mg643.00€MPEP hydrochloride
CAS:MPEP hydrochloride is an effective and highly specific non-competitive antagonist at the mGlu5 receptor subtype (IC50: 36 nM).Formula:C14H12ClNPurity:99.87% - >99.99%Color and Shape:SolidMolecular weight:229.7(S)-3-Hydroxyphenylglycine
CAS:(S)-3-Hydroxyphenylglycine is an agonist of group I metabotropic glutamate receptors (mGluRs).Formula:C8H9NO3Purity:99.65%Color and Shape:SolidMolecular weight:167.16TAT-GluA2 3Y acetate(1404188-93-7 free base)
TAT-GluA2 3Y acetate is an inhibitor of AMPA receptor endocytosis.Systemic administration of Tat-GluA2(3Y) during the induction phase of d-amphetamine blockedFormula:C115H185N43O29Purity:99.43%Color and Shape:SolidMolecular weight:2634.02CTEP
CAS:CTEP (RO 4956371) (RO4956371) is a novel, long-acting, orally bioavailable allosteric antagonist of mGlu5 receptor with IC50 of 2.2 nM, shows >1000-foldFormula:C19H13ClF3N3OPurity:99.17%Color and Shape:SolidMolecular weight:391.77Ref: TM-T6457
2mg34.00€5mg50.00€1mL*10mM (DMSO)55.00€10mg88.00€25mg138.00€50mg244.00€100mg330.00€200mg470.00€MTEP hydrochloride
CAS:MTEP hydrochloride (MTEP) is non-competitive mGlu5 antagonist (IC50 and Ki of 5 nM and 16 nM, respectively)Formula:C11H9ClN2SPurity:99.58%Color and Shape:SolidMolecular weight:236.721-BCP
CAS:1-BCP (Piperonylic acid piperidide) is a centrally active drug that modulates AMPA receptor gated currents.Formula:C13H15NO3Purity:99.60%Color and Shape:SolidMolecular weight:233.26SIB-1757
CAS:SIB-1757 (6-methyl-2-[(E)-phenyldiazenyl]pyridin-3) is a selective antagonist of mGlu5 metabotropic glutamate receptor subtype (hmGlu5, IC50 : 0.4 μM)Formula:C12H11N3OPurity:97.37%Color and Shape:SolidMolecular weight:213.24Lu AF21934
CAS:Lu AF21934 is a brain-penetrant and selective mGlu4 receptor positive allosteric modulator (IC50: 500 nM, human).Formula:C14H16Cl2N2O2Purity:99.79%Color and Shape:SolidMolecular weight:315.2trans-ACPD
CAS:trans-ACPD ((±)-trans-ACPD) is an equimolecular mixture of (1S, 3R)- and (1R, 3S)-ACPD.Formula:C7H11NO4Purity:99.53%Color and Shape:SolidMolecular weight:173.17Ref: TM-T3484
1mg46.00€2mg59.00€1mL*10mM (DMSO)71.00€5mg94.00€10mg140.00€25mg264.00€50mg477.00€100mg692.00€IDRA-21
CAS:IDRA-21 is a positive AMPA receptor modulator.Formula:C8H9ClN2O2SPurity:99.73%Color and Shape:SolidMolecular weight:232.69LY-404187
CAS:LY404187 is a positive allosteric modulator of AMPA receptorsFormula:C19H22N2O2SPurity:99.34%Color and Shape:SolidMolecular weight:342.46Ref: TM-T7706
2mg35.00€5mg52.00€1mL*10mM (DMSO)58.00€10mg90.00€25mg164.00€50mg239.00€100mg339.00€200mg472.00€HBT1
CAS:HBT1 is an AMPA receptor potentiator that induces production of brain-derived neurotrophic factor (BDNF) and exhibits little agonistic effect in primary neuronsFormula:C16H17F3N4O2SPurity:99.52%Color and Shape:SolidMolecular weight:386.39VU-1545
CAS:VU-1545 is mGlu5 positive allosteric modulator.Formula:C22H15FN4O3Purity:98.8%Color and Shape:SolidMolecular weight:402.38VU 0357121
CAS:VU0357121, a positive allosteric modulator of mGlu5 (EC50: 33 nM), is inactive or very weakly antagonizing at other mGlu receptor subtypes.Formula:C17H17F2NO2Purity:99% - >99.99%Color and Shape:SolidMolecular weight:305.32Ro0711401
CAS:Ro0711401 is an agonist of mGlu1 receptor.Formula:C18H11F3N2O3Purity:97.57%Color and Shape:SolidMolecular weight:360.29VU0364770
CAS:VU0364770 (VU 0364770)(EC50=1.1 μM), a positive allosteric modulator(PAM) of mGlu4, shows insignificant activity at 68 other receptors, including other mGluFormula:C12H9ClN2OPurity:99.65% - >99.99%Color and Shape:SolidMolecular weight:232.67YM90K
CAS:YM90K (6-(1H-imidazol-1-yl)-7-nitro-2,3(1H,4H)-) hydrochloride is an antagonist of AMPA receptor.Formula:C11H8ClN5O4Purity:98.23%Color and Shape:SolidMolecular weight:309.66Ref: TM-T8435
1mg73.00€5mg160.00€1mL*10mM (DMSO)170.00€10mg245.00€25mg404.00€50mg567.00€100mg767.00€200mg1,018.00€Ref: TM-T8862
1mg34.00€5mg75.00€1mL*10mM (DMSO)87.00€10mg110.00€25mg245.00€50mg363.00€100mg515.00€200mg702.00€FITM
CAS:FITM is a potent negative allosteric modulator of mGlu1 receptor(Ki : 2.5 nM).Formula:C18H18FN5OSPurity:97.25% - 99.23%Color and Shape:SolidMolecular weight:371.43Ref: TM-T7292
1mg34.00€2mg44.00€1mL*10mM (DMSO)62.00€5mg66.00€10mg92.00€25mg177.00€50mg268.00€100mg394.00€MPEP
CAS:MPEP is a selective mGlu5 receptor antagonist with IC50 of 36 nM, exhibits no appreciable activity at mGlu1b/2/3/4a/7b/8a/6 receptors.Formula:C14H11NPurity:99.54%Color and Shape:SolidMolecular weight:193.24pep2-SVKI acetate
Pep2-SVKI acetate(pep2-SVKI acetate (328944-75-8 free base)) is a synthetic peptide salt that prevents internalization of AMPA-type glutamate receptor.Formula:C62H97N13O20Purity:97.14%Color and Shape:SolidMolecular weight:1344.51TCN238
CAS:TCN238 is an orally bioavailable positive allosteric modulator of the metabotropic glutamate receptor 4 (mGluR4with an EC50 of 1 μM).Formula:C12H11N3Purity:99.9% - 99.92%Color and Shape:SolidMolecular weight:197.24CNQX
CAS:CNQX (FG9065) is a competitive, non-NMDA glutamate receptor antagonist (IC50s = 0.3 and 1.5 μM for AMPA and kainate receptors, respectively)Formula:C9H4N4O4Purity:99.70%Color and Shape:Pale Yellow SolidMolecular weight:232.15AMN082 free base
CAS:AMN082 free base is a metabotropic glutamate receptor 7 allosteric agonist.Formula:C28H28N2Purity:97.75% - 97.79%Color and Shape:SolidMolecular weight:392.54Ref: TM-T21935L
5mg48.00€1mL*10mM (DMSO)50.00€10mg71.00€25mg128.00€50mg200.00€100mg323.00€200mg450.00€MTEP
CAS:MTEP: potent, selective mGluR5 antagonist; IC50=5 nM, Ki=16 nM; may have antidepressant/anxiolytic effects; useful in Parkinson's research.Formula:C11H8N2SColor and Shape:SolidMolecular weight:200.26CX516
CAS:CX516 (Ampalex), an ampakine and nootropic, acts as an AMPA receptor positive allosteric modulator as a therapy for Alzheimer's disease, schizophrenia and MCI.Formula:C14H15N3OPurity:99.04% - ≥95%Color and Shape:Tan SolidMolecular weight:241.293-MATIDA
CAS:3-MATIDA is an effective mGluR-1 antagonist (IC50: 6.3 μM, rat mGluR-1a).Formula:C8H9NO4SPurity:99.75% - 99.96%Color and Shape:SolidMolecular weight:215.23Ref: TM-T3486
2mg34.00€5mg49.00€1mL*10mM (DMSO)49.00€10mg79.00€25mg145.00€50mg227.00€100mg339.00€200mg482.00€VU0155094
CAS:VU0155094 (ML 397) is a positive allosteric modulator with differential activity at the various group III mGluRs.Formula:C24H24N2O4SPurity:97.21%Color and Shape:SolidMolecular weight:436.52Ref: TM-T9011
1mg62.00€5mg110.00€1mL*10mM (DMSO)127.00€10mg161.00€25mg269.00€50mg371.00€100mg537.00€200mg710.00€Caroverine hydrochloride
CAS:Caroverine HCL: Blocks NMDA/AMPA receptors, antioxidant, calcium-blocker, and vasorelaxant, used for tinnitus research.Formula:C22H28ClN3O2Purity:98.37% - 98.75%Color and Shape:SolidMolecular weight:401.9
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