GluR
Glutamate Receptor inhibitors are compounds that block the activity of glutamate receptors, which are the main excitatory neurotransmitter receptors in the brain. These receptors play a pivotal role in synaptic transmission, plasticity, learning, and memory. Dysregulation of glutamate signaling is associated with various neurological disorders, including epilepsy, stroke, and neurodegenerative diseases. GluR inhibitors are essential for investigating the mechanisms of excitotoxicity and developing neuroprotective strategies. At CymitQuimica, we offer a range of glutamate receptor inhibitors to support your research in synaptic function, neuroprotection, and cognitive disorders.
Found 255 products of "GluR"
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NBQX disodium
CAS:<p>NBQX Disodium (FG9202 disodium) is a highly selective, competitive AMPA receptor antagonist with neuroprotective and anticonvulsant activity.</p>Formula:C12H6N4Na2O6SPurity:97.6% - 98.22%Color and Shape:SolidMolecular weight:380.2415Basimglurant
CAS:<p>Basimglurant (CTEP Derivative) is a potent, selective and orally available modulator of mGlu5 negative allosteric(Kd of 1.1 nM).</p>Formula:C18H13ClFN3Purity:98.35%Color and Shape:SolidMolecular weight:325.77AZD-8529 mesylate
CAS:<p>AZD-8529 mesylate is a highly selective, and orally bioavailable positive allosteric modulator of mGluR2 (EC50: 285 nM).</p>Formula:C25H28F3N5O6SPurity:99.19%Color and Shape:SolidMolecular weight:583.58DHPG
CAS:<p>DHPG is a potent Group I mGluR agonist; doesn't affect Group II/III; linked to phospholipase D.</p>Formula:C8H9NO4Purity:99.55%Color and Shape:SolidMolecular weight:183.16Org-26576
CAS:<p>Org-26576 is a positive allosteric modulator of the AMPA receptor.</p>Formula:C11H12N2O2Purity:99.67%Color and Shape:SolidMolecular weight:204.23(R)-3,4-DCPG HCl
<p>(R)-3,4-DCPG HCl is a potent and selective mGlu8a receptor agonist that activates metabotropic glutamate receptors on primary afferent terminals in the neonatal</p>Formula:C10H10ClNO6Purity:98.80% - 99.89%Color and Shape:SoildMolecular weight:275.64LY339434 HCl
<p>LY339434 HCl is a low affinity GluR5 erythrocyte receptor agonist.LY339434 HCl causes rapid neuronal death primarily by affecting N-methyl-D-aspartate (NMDA)</p>Formula:C18H20ClNO4Purity:97.96% - 99.68%Color and Shape:SoildMolecular weight:349.81Decoglurant
CAS:<p>Decoglurant (RO4995819) is a negative allosteric modulator of mGluR2 and mGluR3 and it also is developed as an antidepressant.</p>Formula:C21H11F6N5Purity:99.77%Color and Shape:SolidMolecular weight:447.34(R)-ADX-47273
CAS:<p>(R)-ADX-47273 is a potent mGluR5 positive allosteric modulator(EC50 of 168 nM for potentiation ).</p>Formula:C20H17F2N3O2Purity:99.87%Color and Shape:SolidMolecular weight:369.36Piracetam
CAS:<p>Piracetam (UCB-6215), a cyclic derivative of the neurotransmitter gamma-aminobutyric acid (GABA), is used in therapy of the extensive cognitive disorders.</p>Formula:C6H10N2O2Purity:97.16%Color and Shape:Crystals From Isopropanol SolidMolecular weight:142.16VU0650786
CAS:<p>VU0650786: selective mGlu3 NAM, CNS-penetrant, IC50 392 nM, shows antidepressant/anxiolytic effects in rodents.</p>Formula:C18H15ClFN5O2Purity:99.09%Color and Shape:SolidMolecular weight:387.8γ-DGG acetate(6729-55-1 free base)
CAS:<p>gamma-DGG acetate(6729-55-1 free base) (γ-D-Glutamylglycine) is a competitive blocker of AMPA receptor.</p>Formula:C9H16N2O7Purity:99.81%Color and Shape:SolidMolecular weight:264.23KM02894
CAS:<p>KM02894 inhibits glutamate release, potentially reducing cancer-induced bone pain in tumor studies.</p>Formula:C7H9N3OS2Purity:99.98%Color and Shape:SolidMolecular weight:215.3MPPG
CAS:<p>MPPG is a selective L-AP4-sensitive receptor antagonist (kD=9.2 μM).</p>Formula:C9H12NO5PColor and Shape:SolidMolecular weight:245.171(S)-3,4-DCPG HCl
<p>(S)-3,4-DCPG HCl is a selective mGluR8a agonist, impacting AV12-664 cells with an EC50 of 31 nM.</p>Formula:C10H10ClNO6Purity:99.53% - 99.9%Color and Shape:SoildMolecular weight:275.64(S)-3,4-DCPG
CAS:<p>(S)-3,4-DCPG ((S)-3,4-Dicarboxyphenylglycine) is a selective agonist of human metabotropic glutamate receptor 8a (mGluR8a).</p>Formula:C10H9NO6Purity:98%Color and Shape:SolidMolecular weight:239.18LY3020371
CAS:<p>LY3020371: potent, selective mGlu 2/3 receptor antagonist with Ki of 5.26 nM (hmGluR2) and 2.50 nM (hmGluR3); key in depression studies.</p>Formula:C15H15F2NO5SColor and Shape:SolidMolecular weight:359.34LY3027788
CAS:<p>LY3027788, potent oral prodrug of LY3020371, is a strong mGlu2/3 antagonist with notable antidepressant effects.</p>Formula:C25H31F2NO11SColor and Shape:SolidMolecular weight:591.58mGluR3 modulator-1
CAS:<p>1-ethyl-3-morpholin-4-yl tetrahydroisoquinoline: mGluR3 modulator, potential for Parkinson's.</p>Formula:C16H21N3OPurity:98.99%Color and Shape:SolidMolecular weight:271.36LY2812223
CAS:<p>LY2812223: selective mGlu2 agonist; binds mGlu2/mGlu3 (Ki=144/156 nM).</p>Formula:C10H12N4O4SPurity:98%Color and Shape:SolidMolecular weight:284.291H-Pyrrolo[2,1-c][1,2,4]benzothiadiazine, 2,3,3a,4-tetrahydro-, 5,5-dioxide, (3aR)-
CAS:<p>1H-Pyrrolo[2,1-c][1,2,4]benzothiadiazine, 2,3,3a,4-tetrahydro-, 5,5-dioxide, (3aR)- is a low activity isomer of S 18986.</p>Formula:C10H12N2O2SPurity:99.96%Color and Shape:SoildMolecular weight:224.28Pomaglumetad methionil anhydrous
CAS:<p>LY2140023, potential schizophrenia treatment, is an oral prodrug of LY404039, a selective mGlu2/3 agonist.</p>Formula:C12H18N2O7S2Purity:98%Color and Shape:SolidMolecular weight:366.41STX-107
CAS:<p>STX-107 is a potent and selective mGluR5 agonist for the study of Fragile X Syndrome.</p>Formula:C18H10FN3SPurity:99.17%Color and Shape:SolidMolecular weight:319.36VU0483605
CAS:<p>VU0483605 is an effective and selective positive allosteric modulator of mGluR1 with EC50s of 390 and 356 nM for human and rat, respectively.</p>Formula:C20H10Cl3N3O3Purity:99.61%Color and Shape:SolidMolecular weight:446.67ML353
<p>ML353 activates TREK-1/2, binds mGlu5 SAM (Ki=18.2 nM), surpasses 5mpep, may address SAM activity/blocking.</p>Formula:C19H15FN2OPurity:99.98% - 99.98%Color and Shape:SoildMolecular weight:306.33mGluR5 modulator 1
CAS:<p>mGluR5 modulator 1 is a positive modulator for mGluR5, used in schizophrenia and cognitive research.</p>Formula:C18H19ClFN3O2Color and Shape:SolidMolecular weight:363.82KRP-199 sodium
<p>KRP-199 sodium sodium is highly potent and selective for AMPA-R in vitro and exhibits good neuroprotection in vivo.</p>Formula:C22H12F3N5Na2O7Purity:97.27%Color and Shape:SoildMolecular weight:561.33(S)-AMPA HCl
<p>(S)-AMPA HCl (L-AMPA HCl) is a selective AMPA receptor agonist with potential antidepressant activity. It can be used in research on Parkinson's disease.</p>Formula:C7H11ClN2O4Purity:99.18%Color and Shape:SolidMolecular weight:222.63MGS0274
CAS:<p>MGS0274, a lipophilic prodrug of mGlu2/3 agonist MGS0008, enhances oral bioavailability, potentially aiding schizophrenia research.</p>Formula:C21H32FNO7Color and Shape:SolidMolecular weight:429.485L-AP3
CAS:<p>L-AP3 blocks mGluR, inhibits D/L-phosphoserine (IC50: 368/2087 μM).</p>Formula:C3H8NO5PColor and Shape:White Hygroscopic SolidMolecular weight:169.073MMPIP hydrochloride
CAS:<p>MMPIP hydrochloride is a selective antagonist of allosteric mGluR7.</p>Formula:C19H16ClN3O3Purity:99.88%Color and Shape:SolidMolecular weight:369.8(S,S)-BMS-984923
CAS:<p>(S,S)-BMS-984923 is a weak mGluR5 modulator with EC50 >1μM; less active than its potent counterpart.</p>Formula:C22H15ClN2O2Color and Shape:SolidMolecular weight:374.82LY3027788 hydrochloride
CAS:<p>LY3027788 HCl, potent oral prodrug of LY3020371, targets mGlu2/3 with antidepressant effects.</p>Formula:C25H32ClF2NO11SColor and Shape:SolidMolecular weight:628.03(±)-LY367385
CAS:<p>(±)-LY367385 is the racemic form of LY367385, and LY367385 is a highly potent and selective mGluR1a antagonist.</p>Formula:C10H11NO4Color and Shape:SolidMolecular weight:209.201JF-NP-26
<p>Releases pain-blocking raseglurant under 405 nm light. Inhibits Quisqualate. Analgesic in vivo. Quantum yield: 0.18.</p>Color and Shape:SolidMGS0028
CAS:<p>MGS0028 is a selective agonist of metabotropic glutamate 2/3 receptor, it could reverse abnormal behaviors in mice induced by isolation rearing.</p>Formula:C8H8FNO5Color and Shape:SolidMolecular weight:217.15GYKI-47261 dihydrochloride
CAS:<p>GYKI-47261 dihydrochloride is an AMPA receptor antagonist and CYP2E1 inducer, demonstrating broad-spectrum anticonvulsant and neuroprotective activities.</p>Formula:C18H17Cl3N4Purity:98.32% - 99.14%Color and Shape:SolidMolecular weight:395.71VU0364770 hydrochloride
CAS:<p>VU0364770 hydrochloride: potent, selective mGlu4 PAM; EC50=290 nM (rat), 1.1 μM (human).</p>Formula:C12H10Cl2N2OPurity:98%Color and Shape:SolidMolecular weight:269.13NS-102
CAS:<p>NS-102 is a glutamate receptor and NMDA receptor antagonist that inhibits erythrocyanine (GluK2) and inhibits specific binding to the glur6 receptor.</p>Formula:C12H11N3O4Purity:98.48% - 98.95%Color and Shape:SolidMolecular weight:261.23JNJ-46778212
CAS:<p>JNJ-46778212 (VU 0409551) is a selective and potent mGlu5 allosteric modulator (EC50: 260 nM) for the study of neurodissection.</p>Formula:C20H17FN2O3Purity:99.24%Color and Shape:SolidMolecular weight:352.36LY341495
CAS:<p>LY341495 is a potent metabotropic glutamate receptor antagonist and can be used to study neurological disorders.</p>Formula:C20H19NO5Purity:98.53% - 99.37%Color and Shape:SolidMolecular weight:353.37VU0422288
CAS:<p>VU0422288 (ML396) is a type III mGlu receptor (mGlus) orthosteric modulator with inhibitory effects on mGluR4.VU0422288 can be used to study Rett syndrome.</p>Formula:C17H11Cl2N3O2Purity:95.48%Color and Shape:SolidMolecular weight:360.19GYKI 53655 hydrochloride
CAS:<p>GYKI 53655 hydrochloride (LY300168 hydrochloride) is an antagonist of AMPA and is used in the study of neurological disorders.</p>Formula:C19H21ClN4O3Purity:98.02%Color and Shape:SolidMolecular weight:388.85Ro 01-6128
CAS:<p>Positive allosteric modulator of mGlu1 receptors</p>Formula:C17H17NO3Purity:98%Color and Shape:SolidMolecular weight:283.32AMN082
CAS:<p>AMN082 is an mGluR7 agonist with antidepressant effects. Neuroprotective effect of AMN082 on neuronal apoptosis in rats with traumatic brain injury.</p>Formula:C28H30Cl2N2Purity:97.13% - 98.63%Color and Shape:SolidMolecular weight:465.46EGLU
CAS:<p>EGLU, an antidepressant and potent mGluR-2 antagonist, binds with a 66 μM Kd to (lS,3S)-ACPD sites.</p>Formula:C7H13NO4Purity:99.98%Color and Shape:SolidMolecular weight:175.18GYKI 52466 dihydrochloride
CAS:<p>GYKI 52466 dihydrochloride is an AMPA/Kainate receptor antagonist with anticonvulsant activity and can be used to study neurological diseases.</p>Formula:C17H17Cl2N3O2Purity:99.38%Color and Shape:SolidMolecular weight:366.24γ-DGG
CAS:<p>gamma-DGG is a competitive blocker of AMPA receptor.</p>Formula:C7H12N2O5Purity:98%Color and Shape:SolidMolecular weight:204.18LY487379
CAS:<p>LY487379: human mGluR2 PAM, boosts glutamate binding, aids cognitive flexibility, may treat schizophrenia. EC50: 1.7 μM (mGlu2), >10 μM (mGlu3).</p>Formula:C21H19F3N2O4SColor and Shape:SolidMolecular weight:452.45VU-1545
CAS:<p>VU-1545 is mGlu5 positive allosteric modulator.</p>Formula:C22H15FN4O3Purity:98.8%Color and Shape:SolidMolecular weight:402.38MPEP hydrochloride
CAS:<p>MPEP hydrochloride is an effective and highly specific non-competitive antagonist at the mGlu5 receptor subtype (IC50: 36 nM).</p>Formula:C14H12ClNPurity:99.87% - >99.99%Color and Shape:SolidMolecular weight:229.7Lu AF21934
CAS:<p>Lu AF21934 is a brain-penetrant and selective mGlu4 receptor positive allosteric modulator (IC50: 500 nM, human).</p>Formula:C14H16Cl2N2O2Purity:99.79%Color and Shape:SolidMolecular weight:315.2AZD-8529
CAS:<p>AZD-8529: selective, oral mGluR2 modulator, EC50 285 nM; inactive on mGluR1,3-8 at 20-25 M.</p>Formula:C24H24F3N5O3Color and Shape:SolidMolecular weight:487.47ADX-47273
CAS:<p>ADX-47273 (BA 94673139) is a positive and selective allosteric modulator for the metabotropic glutamate receptor subtype mGluR5(EC50=170 nM).</p>Formula:C20H17F2N3O2Purity:97% - 99.18%Color and Shape:SolidMolecular weight:369.36Chelidamic acid
CAS:<p>Chelidamic acid is a heterocyclic organic acid with a pyran skeleton. Chelidamic acid is inhibitors of glutamate decarboxylase, with a Ki of 33 μM.</p>Formula:C7H5NO5Purity:98.11%Color and Shape:Pale Yellow PowderMolecular weight:183.12ADX88178
CAS:<p>ADX88178 is a potent positive allosteric modulator for metabotropic glutamate receptor 4 (mGluR4) with EC50 of 4 nM for human mGluR4.</p>Formula:C12H12N6SPurity:99.55%Color and Shape:SolidMolecular weight:272.33(S)-ATPO
CAS:<p>(S)-ATPO is Competitive antagonist at GluR1-4 (AMPA-preferring) receptors.</p>Formula:C11H19N2O7PPurity:98.37% - 99.41%Color and Shape:SolidMolecular weight:322.25VU0364770
CAS:<p>VU0364770 (VU 0364770)(EC50=1.1 μM), a positive allosteric modulator(PAM) of mGlu4, shows insignificant activity at 68 other receptors, including other mGlu</p>Formula:C12H9ClN2OPurity:99.65% - >99.99%Color and Shape:SolidMolecular weight:232.67VU0155094
CAS:<p>VU0155094 (ML 397) is a positive allosteric modulator with differential activity at the various group III mGluRs.</p>Formula:C24H24N2O4SPurity:97.21%Color and Shape:SolidMolecular weight:436.52VU0155041
CAS:<p>VU0155041 is an effective and positive allosteric modulator/allosteric agonist at mGlu4 receptors (EC50: 798/693 nM, at human/rat).</p>Formula:C14H15Cl2NO3Purity:99.52% - 99.56%Color and Shape:SolidMolecular weight:316.18Farampator
CAS:<p>Farampator (CX-691) (CX-691;Org24448) is a positive modulator of AMPA receptor.</p>Formula:C12H13N3O2Purity:99.84% - >99.99%Color and Shape:SolidMolecular weight:231.25JNJ-40411813
CAS:<p>JNJ-40411813 (ADX-71149) (ADX-71149) is a new positive allosteric modulator of the metabotropic glutamate 2 receptor (mGlu2R, EC50: 147 nM).</p>Formula:C20H25ClN2OPurity:99.74%Color and Shape:SolidMolecular weight:344.88XAP044
CAS:<p>XAP044 blocks mGlu7, inhibiting long-term potentiation in mouse brain with a half-maximal effect at 88nm.</p>Formula:C15H9IO4Purity:97.41%Color and Shape:SolidMolecular weight:380.13VU 0357121
CAS:<p>VU0357121, a positive allosteric modulator of mGlu5 (EC50: 33 nM), is inactive or very weakly antagonizing at other mGlu receptor subtypes.</p>Formula:C17H17F2NO2Purity:99% - >99.99%Color and Shape:SolidMolecular weight:305.32JNJ16259685
CAS:<p>JNJ16259685 (TN.T 16259685) is a selective mGluR1 antagonist, and inhibits the synaptic activation of mGluR1 in a concentration-dependent manner with IC50 of 19</p>Formula:C20H23NO3Purity:98.31%Color and Shape:SolidMolecular weight:325.4E4CPG
CAS:<p>E4CPG is a novel group I/II metabotropic glutamate receptor antagonist, more potent than (RS)-MCPG.</p>Formula:C11H13NO4Purity:99.96%Color and Shape:SolidMolecular weight:223.23MPEP
CAS:<p>MPEP is a selective mGlu5 receptor antagonist with IC50 of 36 nM, exhibits no appreciable activity at mGlu1b/2/3/4a/7b/8a/6 receptors.</p>Formula:C14H11NPurity:99.54%Color and Shape:SolidMolecular weight:193.24Caroverine hydrochloride
CAS:<p>Caroverine HCL: Blocks NMDA/AMPA receptors, antioxidant, calcium-blocker, and vasorelaxant, used for tinnitus research.</p>Formula:C22H28ClN3O2Purity:98.37% - 98.75%Color and Shape:SolidMolecular weight:401.9NBQX
CAS:<p>NBQX (FG9202) is a potent, selective and competitive AMPA receptor antagonist. Neuroprotective and anticonvulsant; active in vivo.</p>Formula:C12H8N4O6SPurity:97.66% - 99.42%Color and Shape:SolidMolecular weight:336.28CX614
CAS:<p>CX614 is a positive allosteric modulator of the AMPA receptor concerning AMPA.</p>Formula:C13H13NO4Purity:97.37%Color and Shape:SolidMolecular weight:247.25PHCCC
CAS:<p>PHCCC is a Group I mGluR antagonist and enhances mGluR4 function; also blocks mGluR2/8.</p>Formula:C17H14N2O3Purity:>99.99%Color and Shape:SolidMolecular weight:294.3MTEP
CAS:<p>MTEP: potent, selective mGluR5 antagonist; IC50=5 nM, Ki=16 nM; may have antidepressant/anxiolytic effects; useful in Parkinson's research.</p>Formula:C11H8N2SColor and Shape:SolidMolecular weight:200.26SIB-1757
CAS:<p>SIB-1757 (6-methyl-2-[(E)-phenyldiazenyl]pyridin-3) is a selective antagonist of mGlu5 metabotropic glutamate receptor subtype (hmGlu5, IC50 : 0.4 μM)</p>Formula:C12H11N3OPurity:97.37%Color and Shape:SolidMolecular weight:213.24CTEP
CAS:<p>CTEP (RO 4956371) (RO4956371) is a novel, long-acting, orally bioavailable allosteric antagonist of mGlu5 receptor with IC50 of 2.2 nM, shows >1000-fold</p>Formula:C19H13ClF3N3OPurity:99.17%Color and Shape:SolidMolecular weight:391.77Ro0711401
CAS:<p>Ro0711401 is an agonist of mGlu1 receptor.</p>Formula:C18H11F3N2O3Purity:97.57%Color and Shape:SolidMolecular weight:360.29YM90K
CAS:<p>YM90K (6-(1H-imidazol-1-yl)-7-nitro-2,3(1H,4H)-) hydrochloride is an antagonist of AMPA receptor.</p>Formula:C11H8ClN5O4Purity:98.23%Color and Shape:SolidMolecular weight:309.66Ro 67-7476
CAS:<p>Ro 67-7476 is a positive allosteric modulator of mGlu1 receptors.</p>Formula:C17H18FNO2SPurity:99.69%Color and Shape:SolidMolecular weight:319.39(RS)-MCPG
CAS:<p>(RS)-MCPG ((±)-MCPG) is a non-selective group I/II metabotropic glutamate receptor antagonist.</p>Formula:C10H11NO4Purity:99.96%Color and Shape:SolidMolecular weight:209.23-MATIDA
CAS:<p>3-MATIDA is an effective mGluR-1 antagonist (IC50: 6.3 μM, rat mGluR-1a).</p>Formula:C8H9NO4SPurity:99.75% - 99.96%Color and Shape:SolidMolecular weight:215.23CNQX
CAS:<p>CNQX (FG9065) is a competitive, non-NMDA glutamate receptor antagonist (IC50s = 0.3 and 1.5 μM for AMPA and kainate receptors, respectively)</p>Formula:C9H4N4O4Purity:99.70%Color and Shape:Pale Yellow SolidMolecular weight:232.15trans-ACPD
CAS:<p>trans-ACPD ((±)-trans-ACPD) is an equimolecular mixture of (1S, 3R)- and (1R, 3S)-ACPD.</p>Formula:C7H11NO4Purity:99.53%Color and Shape:SolidMolecular weight:173.17TCN238
CAS:<p>TCN238 is an orally bioavailable positive allosteric modulator of the metabotropic glutamate receptor 4 (mGluR4with an EC50 of 1 μM).</p>Formula:C12H11N3Purity:99.9% - 99.92%Color and Shape:SolidMolecular weight:197.24VU0361737
CAS:<p>VU0361737 (ML-128) is a mGlu4 PAM; EC50 is 240 nM (human) and 110 nM (rat), weak at mGlu5/8, inactive at mGlu1/2/3/6/7, CNS-penetrant.</p>Formula:C13H11ClN2O2Purity:99.60% - 99.85%Color and Shape:SolidMolecular weight:262.69AMN082 free base
CAS:<p>AMN082 free base is a metabotropic glutamate receptor 7 allosteric agonist.</p>Formula:C28H28N2Purity:97.75% - 97.79%Color and Shape:SolidMolecular weight:392.54LY-404187
CAS:<p>LY404187 is a positive allosteric modulator of AMPA receptors</p>Formula:C19H22N2O2SPurity:99.34%Color and Shape:SolidMolecular weight:342.46(RS)-3-Hydroxyphenylglycine
CAS:<p>(RS)-3-Hydroxyphenylglycine is a PI-linked metabotropic glutamate receptors agonist.</p>Formula:C8H9NO3Purity:99.29%Color and Shape:SolidMolecular weight:167.16ML 254
CAS:<p>是一种化学合成中的砌块</p>Formula:C18H15FN2O2Purity:98.09%Color and Shape:SolidMolecular weight:310.32(S)-3-Hydroxyphenylglycine
CAS:<p>(S)-3-Hydroxyphenylglycine is an agonist of group I metabotropic glutamate receptors (mGluRs).</p>Formula:C8H9NO3Purity:99.65%Color and Shape:SolidMolecular weight:167.161-BCP
CAS:<p>1-BCP (Piperonylic acid piperidide) is a centrally active drug that modulates AMPA receptor gated currents.</p>Formula:C13H15NO3Purity:99.60%Color and Shape:SolidMolecular weight:233.26FTIDC
CAS:<p>FTIDC: potent, selective mGluR1 allosteric antagonist, weak on mGluR5. IC50: human 5.8 nM, mouse 3.1 nM. Noncompetitive.</p>Formula:C18H23FN6OPurity:94.58%Color and Shape:SolidMolecular weight:358.41MTEP hydrochloride
CAS:<p>MTEP hydrochloride (MTEP) is non-competitive mGlu5 antagonist (IC50 and Ki of 5 nM and 16 nM, respectively)</p>Formula:C11H9ClN2SPurity:99.58%Color and Shape:SolidMolecular weight:236.72CFMTI
CAS:<p>CFMTI: potent mGluR1 allosteric antagonist, 2000x selectivity over mGluR5, IC50: 2.6 nM.</p>Formula:C19H16FN5OPurity:97.23%Color and Shape:SolidMolecular weight:349.36DNQX
CAS:<p>DNQX (FG 9041) is a competitive, non-NMDA glutamate receptor antagonist (IC50s = 0.5 and 0.1 μM for AMPA and kainate receptors, respectively)</p>Formula:C8H4N4O6Purity:97.27% - 99.1%Color and Shape:Off-White Powder With A Yellow TingeMolecular weight:252.14JNJ-42153605
CAS:<p>JNJ-42153605 is a mGlu2 receptor positive allosteric modulator (EC50: 17 nM).</p>Formula:C22H23F3N4Purity:97.25% - 98.57%Color and Shape:SolidMolecular weight:400.44VU 0364439
CAS:<p>VU 0364439 is a mGlu4 positive allosteric modulator (C50: 19.8 nM).</p>Formula:C18H13Cl2N3O3SPurity:97.9%Color and Shape:SolidMolecular weight:422.29CX516
CAS:<p>CX516 (Ampalex), an ampakine and nootropic, acts as an AMPA receptor positive allosteric modulator as a therapy for Alzheimer's disease, schizophrenia and MCI.</p>Formula:C14H15N3OPurity:99.04% - ≥95%Color and Shape:Tan SolidMolecular weight:241.29FITM
CAS:<p>FITM is a potent negative allosteric modulator of mGlu1 receptor(Ki : 2.5 nM).</p>Formula:C18H18FN5OSPurity:97.25%Color and Shape:SolidMolecular weight:371.43VU-29
CAS:<p>VU-29 is a positive allosteric mGlu5 receptor modulator with EC50=9 nM and Ki=244 nM for rmGluR5. It is selective for mGluR5 relative to other mGluR subtypes.</p>Formula:C22H16N4O3Purity:99.63%Color and Shape:SolidMolecular weight:384.39IDRA-21
CAS:<p>IDRA-21 is a positive AMPA receptor modulator.</p>Formula:C8H9ClN2O2SPurity:99.73%Color and Shape:SolidMolecular weight:232.69HBT1
CAS:<p>HBT1 is an AMPA receptor potentiator that induces production of brain-derived neurotrophic factor (BDNF) and exhibits little agonistic effect in primary neurons</p>Formula:C16H17F3N4O2SPurity:99.52%Color and Shape:SolidMolecular weight:386.39(S)-4CPG
CAS:<p>(S)-4CPG ((S)-4-Carboxyphenylglycine) is a competitive mGlu1 receptor antagonist that attenuates nociceptive hypersensitivity and nociceptive abnormalities associated with sciatic nerve constriction injuries in rats, and may be used in the study of neurological disorders.</p>Formula:C9H9NO4Purity:99.96%Color and Shape:SolidMolecular weight:195.17CX717
CAS:<p>CX 717 is a positive allosteric modulator of AMPA receptor which has an antidepressant-like effect.</p>Formula:C11H11N3O3Purity:99.81%Color and Shape:SoildMolecular weight:233.23VU0477886
CAS:<p>VU0477886: Potent mGlu4 PAM, effective in preclinical Parkinson's model HIC.</p>Formula:C20H13ClN4O3Purity:98%Color and Shape:SolidMolecular weight:392.80IEM 1754 2HBr
CAS:<p>IEM 1754 2HBr (IEM 1754 dihydrobromide) is a selective AMPA/kainate receptor blockers for GluR1 and GluR3 with IC50 of 6 μM.</p>Formula:C16H30N2·2HBrPurity:99.71% - 99.72%Color and Shape:SolidMolecular weight:412.25VU6001966
CAS:<p>VU6001966: potent, selective mGlu2 inhibitor (IC50=78 nM), negative modulator, with good CNS penetration.</p>Formula:C17H15FN4O2Purity:98%Color and Shape:SolidMolecular weight:326.33BMT-145027
CAS:<p>BMT-145027 is a positive allosteric modulator of mGluR5 without inherent agonist activity (EC50 = 47 nM).</p>Formula:C23H14ClF3N4Purity:99.62%Color and Shape:SolidMolecular weight:438.83MFZ 10-7 hydrochloride
CAS:<p>MFZ 10-7 hydrochloride is a highly potent and selective negative allosteric modulator of mGluR5 NAM</p>Formula:C15H10ClFN2Purity:98%Color and Shape:SolidMolecular weight:272.71NS 1209
CAS:<p>NS 1209 (SPD 502) is a AMPA receptor antagonist.</p>Formula:C24H27N4NaO7SPurity:98%Color and Shape:SolidMolecular weight:538.55LY392098
CAS:<p>LY392098 (AMPA receptor modulator-3) is an allosteric modulator of AMPA receptor with EC50 of 4.4 μM and can be used in studies about mammalian nervous system.</p>Formula:C18H22FNO2SPurity:99.86%Color and Shape:SolidMolecular weight:335.44VU 0469650
CAS:<p>VU 0469650 is a potent and selective negative allosteric modulator of mGluR1 (IC50 = 99 nM).</p>Formula:C22H28N4OPurity:98.03%Color and Shape:SolidMolecular weight:364.48(1R,2S)-VU0155041
CAS:<p>(1R,2S)-VU0155041 is the cis regioisomer of VU0155041 and a partial agonist of mGluR4.</p>Formula:C14H15Cl2NO3Purity:98.85%Color and Shape:SolidMolecular weight:316.18Methoxy-PEPy
CAS:<p>Methoxy-PEPy is a potent and selective mGlu5 receptor inhibitor with an IC50 value of 1 nM.</p>Formula:C13H10N2OPurity:99.22%Color and Shape:SolidMolecular weight:210.23LYPLAL1-IN-1
CAS:<p>LYPLAL1-IN-1 is a selective covalent small-molecule inhibitor of Lysophospholipase-like 1 (IC50: 0.006 μM). LYPLAL1-IN-1 also enhances glucose production.</p>Formula:C29H29N7O4Purity:98%Color and Shape:SolidMolecular weight:539.59(RS)-MCPG disodium salt
CAS:<p>group I/group II metabotropic glutamate receptor antagonist</p>Formula:C10H11NNaO4Purity:98%Color and Shape:SolidMolecular weight:232.193,3'-Difluorobenzaldazine
CAS:<p>allosteric potentiator of mGlu5</p>Formula:C14H10F2N2Purity:98%Color and Shape:SolidMolecular weight:244.24VU0366248
CAS:<p>VU0366248 is a mGlu5 negative allosteric modulator.</p>Formula:C14H7ClF2N2OPurity:98%Color and Shape:SolidMolecular weight:292.67L-AP4 monohydrate
CAS:<p>L-AP4 (L-APB) is a group III mGluR agonist with EC50s: 0.13μM (mGlu4), 0.29μM (mGlu8), 1.0μM (mGlu6), 249μM (mGlu7).</p>Formula:C4H12NO6PColor and Shape:SolidMolecular weight:201.115VU 0360223
CAS:<p>VU 0360223 is a negative allosteric modulator of mGlu5.</p>Formula:C15H9FN2SPurity:98%Color and Shape:SolidMolecular weight:268.31ADX71743
CAS:<p>ADX71743 is a potent and selective negative allosteric modulator of metabotropic glutamate receptor 7.</p>Formula:C17H19NO2Color and Shape:SolidMolecular weight:269.34mGlu4 receptor agonist 1
CAS:<p>Compound 62, an mGlu4 agonist, has a 308 nM EC50 with anxiolytic and antipsychotic effects.</p>Formula:C21H15ClN4O2Color and Shape:SolidMolecular weight:390.82MAP4
CAS:<p>metabotropic glutamate receptor modulator</p>Formula:C5H12NO5PPurity:98%Color and Shape:White SolidMolecular weight:197.13GRN-529
CAS:<p>GRN-529 is a selective negative allosteric modulator of the mGluR5 receptor.</p>Formula:C22H15F2N3O2Purity:98%Color and Shape:SolidMolecular weight:391.37DFMTI
CAS:<p>DFMTI can completely block the rmGlu1 L757V glutamate response.</p>Formula:C20H18F2N4OColor and Shape:SolidMolecular weight:368.38Z-Cyclopentyl-AP4
CAS:<p>Group III mGlu receptor agonist</p>Formula:C6H12NO5PPurity:98%Color and Shape:SolidMolecular weight:209.14LY456066
CAS:<p>LY456066 is a mGluR1 receptor-selective, negative allosteric modulator.</p>Formula:C19H23N3OSPurity:98%Color and Shape:SolidMolecular weight:341.47JNJ-40068782
CAS:<p>JNJ-40068782 is a potent, selective and systemically active positive allosteric modulator of the mGlu2 receptor.</p>Formula:C21H23N3OPurity:98%Color and Shape:SolidMolecular weight:333.43TASP0433864
CAS:<p>TASP0433864 enhances mGlu2 activity; EC50: 199 nM (human), 206 nM (rat); not an agonist.</p>Formula:C18H23N3O3Purity:98%Color and Shape:SolidMolecular weight:329.39(S)-3,5-DHPG
CAS:<p>group I mGlu receptor agonist</p>Formula:C8H9NO4Purity:98%Color and Shape:SolidMolecular weight:183.16HTL14242
CAS:<p>HTL14242 is a mGlu5 Negative Allosteric Modulator.</p>Formula:C16H8ClFN4Color and Shape:SolidMolecular weight:310.71(RS)-PPG
CAS:<p>(RS)-PPG: Potent, selective III mGluRs agonist; EC50s: hmGluR4a 5.2μM, hmGluR6 4.7μM, hmGluR7b 185μM, hmGluR8a 0.2μM; neuroprotective, anticonvulsive.</p>Formula:C8H10NO5PPurity:98%Color and Shape:SolidMolecular weight:231.14VU0431316
CAS:<p>VU0431316 is a negative mGlu5 allosteric modulator. It has activity in a mouse model of anxiety.</p>Formula:C14H9ClN6O2Purity:98%Color and Shape:SolidMolecular weight:328.71DCG-IV
CAS:<p>DCG-IV: Class II mGluR agonist; anticonvulsant; neuroprotective; EC50: mGlu2R-0.35μM, mGlu3R-0.09μM; antagonizes Group I/III mGluRs.</p>Formula:C7H9NO6Purity:98%Color and Shape:SolidMolecular weight:203.15VU0410425
CAS:<p>VU0410425 is a metabotropic glutamate receptor subtype 1 negative allosteric modulator.</p>Formula:C19H16ClN3O3Purity:98%Color and Shape:SolidMolecular weight:369.8AZ12216052
CAS:<p>AZ12216052 is a GRP8 antagonist with anxiolytic and anti-inflammatory activity and can be used to study obesity and metabolic disorders.</p>Formula:C19H22BrNOSPurity:99.29%Color and Shape:SolidMolecular weight:392.35LY487379 hydrochloride
CAS:<p>Positive allosteric modulator of mGlu2 receptors</p>Formula:C21H20ClF3N2O4SPurity:98%Color and Shape:SolidMolecular weight:488.91VU0361747
CAS:<p>VU0361747 is a positive allosteric modulators (PAM) of metabotropic glutamate receptor subtype 5 (mGlu5).</p>Formula:C19H17FN2O2Color and Shape:SolidMolecular weight:324.35Auglurant
CAS:<p>Auglurant is a novel and selective mGlu5 antagonist (IC50: 11 nM (rat) and an IC50: 14 nM (human)). Auglurant has an acceptable CNS penetration.</p>Formula:C16H12FN5O2Color and Shape:SolidMolecular weight:325.3Desmethyl-YM 298198
CAS:<p>mGlu1-selective antagonist</p>Formula:C17H21ClN4OSPurity:98%Color and Shape:SolidMolecular weight:364.89Foliglurax monohydrochloride
CAS:<p>Foliglurax monohydrochloride, an antiparkinsonian, is a selective brain-penetrant mGluR4 PAM with an EC50 of 79 nM.</p>Formula:C23H24ClN3O3SColor and Shape:SolidMolecular weight:457.97L-CCG-l
CAS:<p>group II metabotropic glutamate receptor agonist</p>Formula:C6H9NO4Purity:98%Color and Shape:SolidMolecular weight:159.14(1S,3R)-ACPD
CAS:<p>(1S,3R)-ACPD is a group I and II mGlu receptor agonist.</p>Formula:C7H11NO4Purity:98%Color and Shape:SolidMolecular weight:173.17VU0404251
CAS:<p>VU0404251 is a positive allosteric modulator of mGlu5.</p>Formula:C19H23FN2O2Color and Shape:SolidMolecular weight:330.4Mavoglurant racemate
CAS:<p>Mavoglurant is a novel, non-competitive mGlu5 receptor antagonist. Mavoglurant (racemate) is the racemate of mavoglurant.</p>Formula:C19H23NO3Purity:98%Color and Shape:SolidMolecular weight:313.39ACPT-II
CAS:<p>metabotropic receptor antagonist</p>Formula:C8H11NO6Purity:98%Color and Shape:SolidMolecular weight:217.18DL-AP4 Sodium salt
CAS:<p>Broad spectrum EAA ligand</p>Formula:C4H10NNaO5PPurity:98%Color and Shape:SolidMolecular weight:206.09UPF-523
CAS:<p>group I metabotropic glutamate receptors (mGlu1a) antagonist</p>Formula:C11H11NO4Purity:98%Color and Shape:White SolidMolecular weight:221.21JNJ-46356479
CAS:<p>JNJ-46356479: Selective, oral mGlu2 receptor PAM, EC50=78 nM, Emax=256%.</p>Formula:C22H22F5N5Color and Shape:SolidMolecular weight:451.44ACPT-I
CAS:<p>Agonist for group III mGlu receptors</p>Formula:C8H11NO6Purity:98%Color and Shape:SolidMolecular weight:217.18VU0364289
CAS:<p>VU0364289 is a positive allosteric modulator of mGlu5.</p>Formula:C20H21N3O2Color and Shape:SolidMolecular weight:335.4(S)-4C3HPG
CAS:<p>group I mGlu1a/1a receptor antagonist and mGluR2 agonist</p>Formula:C9H9NO5Purity:98%Color and Shape:SolidMolecular weight:211.17LSN2814617
CAS:<p>LSN2814617: oral, brain-penetrant mGlu5 PAM, EC50 = 52 nM (human), 42 nM (rat). Promotes wakefulness, useful in schizophrenia study.</p>Formula:C18H20FN5OPurity:98%Color and Shape:SolidMolecular weight:341.38RO4988546
CAS:<p>RO4988546 is a potent negative allosteric modulator of mGlu₂/₃.</p>Formula:C21H10F6N4O3SPurity:98%Color and Shape:SolidMolecular weight:512.38mGluR2 modulator 1
CAS:<p>Potent mGluR2 modulator 1 crosses blood-brain barrier, EC50: 0.03 μM, useful for psychiatric research.</p>Formula:C21H20F3N3O3Color and Shape:SolidMolecular weight:419.4NPEC-caged-LY379268
CAS:<p>NPEC-caged-LY379268 is a type II mGluR agonist [1].</p>Formula:C16H16N2O9Color and Shape:SolidMolecular weight:380.31A 841720
CAS:<p>Potent, selective mGlu1 antagonist A-841720; IC50: 10 nM; 34x selectivity vs mGlu5; analgesic potential.</p>Formula:C17H21N5OSColor and Shape:SolidMolecular weight:343.45RO5488608
CAS:<p>RO5488608 is a new type of high-efficiency mGlu2/3 NAM.</p>Formula:C23H17F3N2O4SColor and Shape:SolidMolecular weight:474.45Talaglumetad hydrochloride
CAS:<p>Talaglumetad hydrochloride, a prodrug of Eglumegad, targets mGluR2/3 to treat psychiatric disorders.</p>Formula:C11H17ClN2O5Color and Shape:SolidMolecular weight:292.72mGluR2 modulator 2
CAS:<p>mGluR2 modulator 2: potent, selective, oral, EC50 = 0.13 μM, for antipsychotic research.</p>Formula:C20H22FN3Color and Shape:SolidMolecular weight:323.41VU0418506
CAS:<p>VU0418506 is a positive allosteric modulator (PAM) of the metabotropic glutamate receptor 4 (mGlu4).</p>Formula:C12H8ClFN4Purity:98%Color and Shape:SolidMolecular weight:262.67ACDPP hydrochloride
CAS:<p>mGlu5 receptor antagonist</p>Formula:C12H13ClN6OPurity:98%Color and Shape:SolidMolecular weight:292.72Ro 64-5229
CAS:<p>mGlu2 antagonist</p>Formula:C17H19Cl2N3OPurity:98%Color and Shape:SolidMolecular weight:352.26VU6010572
CAS:<p>VU6010572: potent, selective mGlu3 modulator, IC50 245 nM, high CNS penetration.</p>Formula:C20H18FNO3Color and Shape:SolidMolecular weight:339.36VU0463841
CAS:<p>VU0463841 is a mGlu5 negative allosteric modulators.</p>Formula:C13H8ClFN4OColor and Shape:SolidMolecular weight:290.68VU 0360172 hydrochloride
CAS:<p>positive allosteric modulator of mGlu5 receptors</p>Formula:C18H16ClFN2OPurity:98%Color and Shape:SolidMolecular weight:330.78mGluR2 modulator 4
CAS:<p>Compound 47 is a potent mGluR2 enhancer with an EC50 of 0.8 μM, potentially useful for antipsychotic research.</p>Formula:C18H18BrN3Color and Shape:SolidMolecular weight:356.26VU0400195
CAS:<p>VU0400195 is a oral effective, positive allosteric modulator of the metabotropic glutamate receptor 4 (mGlu(4)).</p>Formula:C21H16ClN3O3Purity:98%Color and Shape:SolidMolecular weight:393.82(RS)-4-Carboxy-3-hydroxyphenylglycine
CAS:<p>broad spectrum EAA agonist/antagonist</p>Formula:C9H9NO5Purity:98%Color and Shape:SolidMolecular weight:211.17Ro4491533
CAS:<p>Ro4491533 is a potent and selective negative allosteric modulator for group II of the metabotropic glutamate receptors (mGluR2/3).</p>Formula:C24H20F3N3OColor and Shape:SolidMolecular weight:423.43MMPIP
CAS:<p>allosteric mGlu7-selective receptor antagonist</p>Formula:C19H15N3O3Purity:98%Color and Shape:SolidMolecular weight:333.34LSP4-2022
CAS:<p>LSP4-2022, a mGlu4 selective agonist, increases behavioral despair in mouse models of antidepressant action.</p>Formula:C13H18NO8PPurity:100%Color and Shape:SolidMolecular weight:347.26VU0424465
CAS:<p>VU0424465 is a mGlu5-selective allosteric agonist.</p>Formula:C19H19FN2O2Color and Shape:SolidMolecular weight:326.36VU0409106
CAS:<p>VU0409106 is a potent, mGlu5-selective inhibitor.</p>Formula:C15H11FN4O2SPurity:98%Color and Shape:SolidMolecular weight:330.34Remeglurant
CAS:<p>Remeglurant is used as a selective antagonist of the mGlu5 receptor.</p>Formula:C17H15BrN4OColor and Shape:SolidMolecular weight:371.23IEM 1925 dihydrobromide
CAS:<p>AMPA receptor antagonist</p>Formula:C17H30Br2N2Purity:98%Color and Shape:SolidMolecular weight:422.24PHCCC(4Me)
CAS:<p>THCCC, a PHCCC analog, is a dual metabotropic glutamate receptor 2/3 negative/positive allosteric modulator.</p>Formula:C18H16N2O3Color and Shape:SolidMolecular weight:308.33MSOP
CAS:<p>MSOP is a selective antagonist of group III metabotropic glutamate receptor (KD of 51 μM for the L-AP4-sensitive presynaptic mGluR).</p>Formula:C4H10NO6PPurity:98%Color and Shape:SolidMolecular weight:199.1CFMMC
CAS:<p>CFMMC is an allosteric mGluR1 antagonist agent.</p>Formula:C22H28FNO4Color and Shape:SolidMolecular weight:389.46YM 230888
CAS:<p>Selective mGlu1 antagonist</p>Formula:C19H28N4OSPurity:98%Color and Shape:SolidMolecular weight:360.52LY2607540
CAS:<p>LY2607540 is a metabotropic glutamate 2 potentiator with potential anxiolytic/antidepressant properties (EC(50) = 23 and 13 nM, respectively).</p>Formula:C24H24F3N3O4Purity:98%Color and Shape:SolidMolecular weight:475.46(S)-HexylHIBO
CAS:<p>Group I mGlu receptor antagonist</p>Formula:C12H20N2O4Purity:98%Color and Shape:SolidMolecular weight:256.3LSP1-2111
CAS:<p>LSP1-2111 is a mGlu4 receptor subtype agonist.</p>Formula:C12H17N2O9PColor and Shape:SolidMolecular weight:364.25Lu-AF11205
CAS:<p>Lu-AF11205 is a potent positive allosteric modulator (PAM) of mGlu5 receptor.</p>Formula:C17H16N2OSPurity:98%Color and Shape:SolidMolecular weight:296.39(RS)-4-Carboxyphenylglycine
CAS:<p>(RS)-4-Carboxyphenylglycine is a racemic mixture. (S)-4-Carboxyphenylglycine is a selective mGlu1α receptor antagonist.</p>Formula:C9H9NO4Purity:99.04% - >99.99%Color and Shape:SolidMolecular weight:195.17(R)-4-Carboxyphenylglycine
CAS:<p>(R)-4-Carboxyphenylglycine is a NMDA receptor antagonist.</p>Formula:C9H9NO4Purity:98%Color and Shape:SolidMolecular weight:195.17VU0652835
CAS:<p>VU0652835 is a negative allosteric modulator of metabotropic glutamate receptor subtype 5 (mGlu5) (IC50: 81 nM).</p>Formula:C16H19N3O3SPurity:98%Color and Shape:SolidMolecular weight:333.41JNJ-55511118
CAS:<p>JNJ-55511118 is a TARP γ8 allosteric modulator with anticonvulsant activity, which can be used in research on chronic operant alcohol self-administration.</p>Formula:C14H8ClF3N2O2Color and Shape:SolidMolecular weight:328.67DCB
CAS:<p>DCB is an mGluR5 allosteric ligand that blocks mGluR modulation, countering DMeOB and DFB effects.</p>Formula:C14H10Cl2N2Purity:99.12% - 99.9%Color and Shape:SolidMolecular weight:277.15ML337
CAS:<p>ML337 is a negative allosteric modulator of mGlu3 with an IC50 of 593 nM.</p>Formula:C21H20FNO3Purity:99.83%Color and Shape:SolidMolecular weight:353.39LY382884
CAS:<p>LY382884 is a selective and potent GluR5 kainate receptor antagonist with anxiolytic activity.LY382884 blocks blockade of mossy fibre LTP induction.</p>Formula:C18H23NO4Purity:98.32% - 98.71%Color and Shape:SolidMolecular weight:317.38TC-N 22A
CAS:<p>TC-N 22A is a strong, selective, oral active mGlu4 forward allosteric regulator (PAM) that can cross the blood-brain barrier.</p>Formula:C14H13N5SPurity:99.95%Color and Shape:SolidMolecular weight:283.35CPPHA
CAS:<p>CPPHA, a positive allosteric modulator of glutamate receptors mGluR5 and mGluR1, is commonly used in development for central nervous system diseases.</p>Formula:C22H15ClN2O4Purity:98.07%Color and Shape:SolidMolecular weight:406.82ML289
CAS:<p>ML289 is a potent CNS-penetrant mGlu3 modulator with IC50 of 0.66 μM, >15-fold selectivity over mGlu2, and inactive against mGlu5.</p>Formula:C22H23NO3Purity:99.54%Color and Shape:SolidMolecular weight:349.42Foliglurax
CAS:<p>Foliglurax is a highly selective brain-penetrant metabotropic glutamate receptor 4 positive allosteric modulator (mGluR4 PAM) (EC50: 79 nM).</p>Formula:C23H23N3O3SPurity:98%Color and Shape:SolidMolecular weight:421.51VU6001376
CAS:<p>VU6001376 is an effective and selective positive allosteric modulator of the metabotropic glutamate receptor 4 (EC50: 50.1 nM).</p>Formula:C18H14F2N6OSPurity:98%Color and Shape:SolidMolecular weight:400.41Ro 67-4853
CAS:<p>Ro 67-4853 is a positive allosteric modulator of mGluR1, selectively enhancing the response to the agonist (S)-3,5-dihydroxy-phenylglycine (DHPG).</p>Formula:C19H19NO4Purity:98.57%Color and Shape:SolidMolecular weight:325.36VU0155041 sodium
CAS:<p>VU0155041 sodium is a positive allosteric modulator of mGluR4 that promotes extinction in male rats.</p>Formula:C14H14Cl2NNaO3Purity:98%Color and Shape:SolidMolecular weight:338.16HexylHIBO
CAS:<p>HexylHIBO is a type I mGluR antagonist that inhibits mGlu1a and mGlu5a, with Kb values of 140 and 110 μM, respectively.HexylHIBO decreases sEPSC in rats.</p>Formula:C12H20N2O4Purity:99.55%Color and Shape:SolidMolecular weight:256.3(S)-MCPG
CAS:<p>(S)-MCPG is the active isomer of (RS)-MCPG, non-selective group I/group II metabotropic glutamate receptor antagonist.</p>Formula:C10H11NO4Purity:98.72%Color and Shape:SolidMolecular weight:209.20DMeOB
CAS:<p>DMeOB (3,3'-Dimethoxybenzaldazine) is a negative regulator with mGluR5 agonist activity and is used in the study of neurological disorders.</p>Formula:C16H16N2O2Purity:98.34%Color and Shape:SolidMolecular weight:268.31A-794282
CAS:<p>A-794282 is a selective antagonist of mGluR1.</p>Formula:C19H18N4OSPurity:99.87%Color and Shape:SolidMolecular weight:350.44
![1H-Pyrrolo[2,1-c][1,2,4]benzothiadiazine, 2,3,3a,4-tetrahydro-, 5,5-dioxide, (3aR)-](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FT60224.webp&w=3840&q=75)
