Tyrosine Kinase/Adaptors
Tyrosine kinase and adaptor inhibitors are compounds that target tyrosine kinases and their associated adaptor proteins, which play pivotal roles in cell signaling, growth, and differentiation. These inhibitors are essential tools in cancer research, as many tyrosine kinases are involved in the signaling pathways that drive tumor growth and metastasis. By inhibiting tyrosine kinases, these compounds can block critical signaling cascades, offering potential therapeutic strategies for various cancers and other diseases involving abnormal cell signaling. At CymitQuimica, we provide a comprehensive range of high-quality tyrosine kinase and adaptor inhibitors to support your research in oncology, molecular biology, and targeted therapy development.
Subcategories of "Tyrosine Kinase/Adaptors"
- ALK(116 products)
- CSF-1R(42 products)
- EGFR(572 products)
- Ephrin Receptor(23 products)
- FLT(91 products)
- Fibroblast Growth Factor Receptor (FGFR)(169 products)
- HER(5 products)
- Hck(3 products)
- IGF-1R(92 products)
- PDGFR(126 products)
- PYK2(7 products)
- Src(80 products)
- TAM Receptor(32 products)
- Tie-2(21 products)
- Trk receptor(59 products)
- Tyrosine Kinases(26 products)
- VEGFR(262 products)
- c-Fms(108 products)
- c-Kit(102 products)
- c-Met/HGFR(129 products)
- c-RET(51 products)
Show 13 more subcategories
Found 1342 products of "Tyrosine Kinase/Adaptors"
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Vorolanib
CAS:<p>Vorolanib (X-82) is an orally active VEGFR/PDGFR dual inhibitor.</p>Formula:C23H26FN5O3Purity:97.35%Color and Shape:SolidMolecular weight:439.48Fruquintinib
CAS:<p>Fruquintinib (HMPL-013) is an orally available, small molecule inhibitor of vascular endothelial growth factor receptors (VEGFRs), with potential anti-</p>Formula:C21H19N3O5Purity:98.84% - 99.89%Color and Shape:SolidMolecular weight:393.39BIBF0775
CAS:<p>BIBF0775 is a selective TGFβ type I receptor (Alk5) inhibitor (IC50: 34 nM).</p>Formula:C31H34N4O2Purity:99.45% - 99.79%Color and Shape:SolidMolecular weight:494.63AG-13958
CAS:<p>AG-13958 (AG-013958) (AG-013958), a potent VEGFR tyrosine kinase inhibitor, for the treatment of age-related macular degeneration.</p>Formula:C26H22FN7OPurity:99.4%Color and Shape:SolidMolecular weight:467.5Motesanib
CAS:<p>Motesanib (AMG 706) orally blocks VEGFR, PDGFR, Kit, Ret; curbing angiogenesis and cancer cell growth.</p>Formula:C22H23N5OPurity:98% - 99.09%Color and Shape:SolidMolecular weight:373.45zanubrutinib
CAS:<p>Zanubrutinib (BGB-3111) is an inhibitor of Bruton tyrosine kinase (BTK).</p>Formula:C27H29N5O3Purity:98.42% - 99.76%Color and Shape:SolidMolecular weight:471.55Belizatinib
CAS:<p>Belizatinib (TSR-011) is an effective, oral and dual inhibitor of ALK (IC50: 0.7 nM, wild-type recombinant ALK) and TRKA, TRKB, and TRKC.</p>Formula:C33H44FN5O3Purity:99.33% - 99.44%Color and Shape:SolidMolecular weight:577.73Epidermal Growth Factor
CAS:<p>EGF binds EGFR, promotes cell growth & heals diabetic foot ulcers.</p>Formula:C270H401N73O83S7Purity:97.17%Color and Shape:SolidMolecular weight:6222Ibrutinib deacryloylpiperidine
CAS:<p>Ibrutinib deacryloylpiperidine (IBT4A) is a highly selective Bruton’s tyrosine kinase (BTK) irreversible inhibitor with an IC50 of 0.5 nM.</p>Formula:C17H13N5OPurity:99.47%Color and Shape:SolidMolecular weight:303.32CP-380736
CAS:CP-380736 (PF-00520893) inhibits EGFR, a kinase key in cancer-signaling pathways like MAPK, JNK, and Akt.Formula:C14H18N2O5Purity:99.68%Color and Shape:White To Off-White SolidMolecular weight:294.3AZ191
CAS:<p>AZ191（IC50 of 17 nM） is an effective and specific DYRK1B inhibitor.</p>Formula:C24H27N7OPurity:98.04% - 99.65%Color and Shape:SolidMolecular weight:429.52JI-101
CAS:<p>JI-101 (CGI-1842) is an oral multi-kinase inhibitor that targets VEGFR-2, PDGFR-β, and EphB4.</p>Formula:C22H20BrN5O2Purity:99.41% - 99.97%Color and Shape:SolidMolecular weight:466.33RU-301
CAS:<p>RU-301 is a novel pan-tam inhibitor</p>Formula:C21H19F3N4O4SPurity:98.87%Color and Shape:SolidMolecular weight:480.46Ilorasertib
CAS:<p>Ilorasertib (ABT-348) inhibits Aurora kinases A/B/C & RET, PDGFRβ, Flt1 (IC50: 1-120 nM).</p>Formula:C25H21FN6O2SPurity:96.17% - 97.49%Color and Shape:SolidMolecular weight:488.54AZ-5104
CAS:AZ5104 is a potent EGFR inhibitor.Formula:C27H31N7O2Purity:98.40% - 99.59%Color and Shape:Solid PowderMolecular weight:485.58SPP-86
CAS:SPP-86 is an effective and selective cell-permeable inhibitor of RET tyrosine kinase with an IC50 of 8 nM.Formula:C16H15N5Purity:99.53%Color and Shape:SolidMolecular weight:277.32SB-505124
CAS:<p>SB505124 is a selective inhibitor of TGFβR for ALK4, ALK5.</p>Formula:C20H21N3O2Purity:97.19% - 99.92%Color and Shape:SolidMolecular weight:335.4eCF506
CAS:<p>eCF506 is a potent and selective inhibitor of SRC (IC50 < 0.5 nM)</p>Formula:C26H38N8O3Purity:97.85% - 98.16%Color and Shape:SolidMolecular weight:510.63EGFR-IN-12
CAS:<p>EGFR-IN-12 (EGFR Inhibitor) is a cell permeable and selective inhibitor of EGFR kinase (IC50: 21 nM) and blocks receptor autophosphorylation in cells.</p>Formula:C21H18F3N5OPurity:98.3% - 99.76%Color and Shape:SolidMolecular weight:413.4Poziotinib hydrochloride
CAS:<p>Oral poziotinib HCl targets EGFR/HER mutants, inhibiting cancer cell growth.</p>Formula:C23H22Cl3FN4O3Purity:99.69% - 99.81%Color and Shape:SolidMolecular weight:527.8CNX-774
CAS:<p>CNX-774 is a highly specific, irreversible, and orally active BTK inhibitor (IC50<1 nM).</p>Formula:C26H22FN7O3Purity:97.35% - 99.11%Color and Shape:SolidMolecular weight:499.5SAR-20347
CAS:<p>SAR-20347 is an inhibitor of TYK2, JAK1/2/3 (IC50: 0.6/23/26/41 nM).</p>Formula:C21H18ClFN4O4Purity:98.99% - 99.77%Color and Shape:SolidMolecular weight:444.84cFMS Receptor Inhibitor II
CAS:cFMS Receptor Inhibitor II is a CSF1R kinase inhibitorFormula:C23H20N4OPurity:99.8%Color and Shape:SolidMolecular weight:368.43BLU9931
CAS:<p>BLU9931 is the first selective small molecule inhibitor of FGFR4.</p>Formula:C26H22Cl2N4O3Purity:96.958% - 99.85%Color and Shape:SolidMolecular weight:509.38Rebastinib
CAS:<p>DCC-2036 (Rebastinib (DCC-2036)) is a conformational control Bcr-Abl inhibitor for Abl1(WT, IC50: 0.8 nM) and Abl1(T315I, IC50: 4 nM), also inhibits LYN, SRC,</p>Formula:C30H28FN7O3Purity:99.53% - 99.79%Color and Shape:SolidMolecular weight:553.59Methyl 2,5-dihydroxycinnamate
CAS:<p>Methyl 2,5-dihydroxycinnamate is an EGF receptor-associated tyrosine kinases inhibitor.</p>Formula:C10H10O4Purity:99.60%Color and Shape:CrystallineMolecular weight:194.18HG-14-10-04
CAS:<p>HG-14-10-04 is a potent and specific ALK inhibitor.</p>Formula:C29H34ClN7OPurity:99.75% - >99.99%Color and Shape:SolidMolecular weight:532.08PKG Substrate acetate(81187-14-6 free base)
<p>PKG Substrate acetate is a selective substrate for cGMP-dependent protein kinase (PKG).PKG Substrate is a selective substrate for protein kinase G (PKG) with a</p>Formula:C37H71N17O13Purity:99.30%Color and Shape:SolidMolecular weight:962.08UM-164
CAS:<p>UM-164 (DAS-DFGO-II), a highly potent c-Src inhibitor with a dissociation constant (Kd) of 2.7 nM, also effectively inhibits p38α and p38β.</p>Formula:C30H31F3N8O3SPurity:98.72% - 99.52%Color and Shape:SolidMolecular weight:640.68KYL acetate(676657-00-4 free base)
<p>EphA4 inhibitor, Kd: 0.8 μM, IC50: 6.34 μM. Protects synapses and spines, maintains LTP. Long half-life: 8-12h. Neuroprotective.</p>Formula:C76H112N14O19Purity:99.75%Color and Shape:SolidMolecular weight:1525.78EOC317
CAS:<p>EOC317 (ACTB-1003) is an oral kinase inhibitor (IC50: 6/2/4 nM, for FGFR1/VEGFR2/Tie-2).</p>Formula:C27H26F5N7O3Purity:98.00% - 99.26%Color and Shape:SolidMolecular weight:591.53Saracatinib
CAS:<p>Saracatinib (AZD0530) (AZD0530) is an effective Src inhibitor (IC50: 2.7 nM), and effective to Lck, Fyn, Lyn, Blk, Fgr and c-Yes.</p>Formula:C27H32ClN5O5Purity:98% - 99.63%Color and Shape:SolidMolecular weight:542.03Tuxobertinib
CAS:<p>Tuxobertinib (BDTX-189) is a potent and selective inhibitor of allosteric EGFR and HER2 oncogenic mutations. BDTX-189 exhibits anticancer activity.</p>Formula:C29H29ClN6O4Purity:99.22%Color and Shape:SolidMolecular weight:561.03GW786034B
CAS:<p>Pazopanib HCl (Votrient) inhibits VEGFR1-3, PDGFR, FGFR, c-Kit, c-Fms with IC50 range 10-146 nM in cell-free assays.</p>Formula:C21H23N7O2S·HClPurity:99.87%Color and Shape:SolidMolecular weight:473.98LOXO-195
CAS:<p>(6RS)-LOXO-195 (BAY 2731954) is a potent and selective Trk tyrosine kinase inhibitor.</p>Formula:C20H21FN6OPurity:99.54%Color and Shape:SolidMolecular weight:380.42Dovitinib lactate hydrate
CAS:<p>Dovitinib lactate hydrate (TKI258) is the Lactate of Dovitinib, which is a multitargeted RTK inhibitor, mostly for class III (FLT3/c-Kit).</p>Formula:C24H27FN6O4Purity:99.82%Color and Shape:SolidMolecular weight:482.51Olafertinib
CAS:<p>Olafertinib (RX-518) is a novel mutant-selective, irreversible, orally available EGFR inhibitor. It can overcome T790M-mediated resistance in NSCLC.</p>Formula:C29H28F2N6O2Purity:98.62% - 99.706%Color and Shape:SolidMolecular weight:530.57ALK-IN-1
CAS:<p>ALK-IN-1 is a potent ALK inhibitor, demonstrating the ability to overcome Crizotinib resistance mediated by an L1196M mutation.</p>Formula:C26H34ClN6O2PPurity:99.74% - 99.80%Color and Shape:SolidMolecular weight:529.01Zorifertinib
CAS:Zorifertinib (AZD3759) is an orally active, effective and central nervous system-penetrant EGFR inhibitor.Formula:C22H23ClFN5O3Purity:98.20% - 99.36%Color and Shape:White To Off-White SolidMolecular weight:459.9ML167
CAS:<p>ML167 (CID44968231) is a highly selective Cdc2-like kinase 4 (Clk4) inhibitor.</p>Formula:C19H17N3O3Purity:99.82% - >99.99%Color and Shape:SolidMolecular weight:335.36MTX-211
CAS:<p>MTX-211, an inhibitor of EGFR and PI3K, is used for the therapy of cancer and other diseases.</p>Formula:C20H14Cl2FN5O2SPurity:97.6% - >99.99%Color and Shape:SolidMolecular weight:478.33TCS 359
CAS:<p>TCS 359 (FLT3 Inhibitor) is a potent FLT3 inhibitor with IC50 of 42 nM.</p>Formula:C18H20N2O4SPurity:99.31%Color and Shape:SolidMolecular weight:360.43GSK3179106
CAS:<p>GSK3179106 is RET kinase inhibitor with an IC50 of 0.4 nM</p>Formula:C22H21F4N3O4Purity:99.8% - 99.90%Color and Shape:SolidMolecular weight:467.41Desmethyl Erlotinib hydrochloride
CAS:<p>Desmethyl Erlotinib hydrochloride (OSI 420) is an active metabolite of erlotinib which is an orally active EGFR tyrosin kinase inhibitor.</p>Formula:C21H21N3O4·HClPurity:99.49%Color and Shape:SolidMolecular weight:415.87Bafetinib
CAS:<p>Bafetinib (INNO-406): Dual Bcr-Abl/Lyn inhibitor; IC50: 5.8/19 nM; ineffective against T315I mutant, less on c-Kit/PDGFR.</p>Formula:C30H31F3N8OPurity:94.16% - 99.68%Color and Shape:SolidMolecular weight:576.62XL 999
CAS:<p>Tyrosine kinase-IN-1 is a multi-targeted tyrosine kinase inhibitor（KDR, Flt-1, FGFR1 and PDGFRα with IC50s of 4nM, 20nM, 4nM, 2 nM ,respectively）</p>Formula:C26H28FN5OPurity:98.24% - 99.55%Color and Shape:SolidMolecular weight:445.53LDN-212854
CAS:<p>LDN-212854 (BMP Inhibitor III), a novel BMP inhibitor, exhibits greater selectivity for BMP versus the TGF-β type I receptors.</p>Formula:C25H22N6Purity:98% - 98.71%Color and Shape:SolidMolecular weight:406.48SB 525334
CAS:<p>SB-525334 is a potent and selective inhibitor of the TGF-β1R and ALK5 (IC50: 14.3 nM).</p>Formula:C21H21N5Purity:98.39% - ≥95%Color and Shape:SolidMolecular weight:343.42ANA-12
CAS:<p>ANA-12 is a potent and selective TrkB antagonist with anxiolytic and antidepressant activity in mice.</p>Formula:C22H21N3O3SPurity:99.28% - 99.87%Color and Shape:SolidMolecular weight:407.49Repotrectinib
CAS:<p>Repotrectinib (TPX-0005) is a potent ALK/ROS1/TRK inhibitor, with IC50 of 1.01/5.3/1.08/1.26 nM for WT ALK, SRC, ALK L1196M and ALK G1202R, respectively.</p>Formula:C18H18FN5O2Purity:99.92% - >99.99%Color and Shape:SolidMolecular weight:355.37
