Tyrosine Kinase/Adaptors
Tyrosine kinase and adaptor inhibitors are compounds that target tyrosine kinases and their associated adaptor proteins, which play pivotal roles in cell signaling, growth, and differentiation. These inhibitors are essential tools in cancer research, as many tyrosine kinases are involved in the signaling pathways that drive tumor growth and metastasis. By inhibiting tyrosine kinases, these compounds can block critical signaling cascades, offering potential therapeutic strategies for various cancers and other diseases involving abnormal cell signaling. At CymitQuimica, we provide a comprehensive range of high-quality tyrosine kinase and adaptor inhibitors to support your research in oncology, molecular biology, and targeted therapy development.
Subcategories of "Tyrosine Kinase/Adaptors"
- ALK(129 products)
- CSF-1R(42 products)
- EGFR(591 products)
- Ephrin Receptor(25 products)
- FLT(90 products)
- Fibroblast Growth Factor Receptor (FGFR)(183 products)
- HER(3 products)
- Hck(3 products)
- IGF-1R(104 products)
- PDGFR(127 products)
- PYK2(7 products)
- Src(81 products)
- TAM Receptor(33 products)
- Tie-2(20 products)
- Trk receptor(57 products)
- Tyrosine Kinases(25 products)
- VEGFR(246 products)
- c-Fms(112 products)
- c-Kit(115 products)
- c-Met/HGFR(137 products)
- c-RET(62 products)
Show 13 more subcategories
Found 1167 products of "Tyrosine Kinase/Adaptors"
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
cis-NVP-ADW742
CAS:NVP-ADW742 is an IGF-1R inhibitor with IC50 of 0.17 μM, >16-fold more potent against IGF-1R than InsR; little activity to HER2, PDGFR, VEGFR-2, Bcr-Abl and c-Kit.Formula:C28H31N5OColor and Shape:SolidMolecular weight:453.59Zenocutuzumab
CAS:Zenocutuzumab (MCLA-128) is a humanized antibody targeting HER2, used for research on tumors driven by NRG1 gene rearrangement.Purity:97%Color and Shape:LiquidMolecular weight:145.76 kDaVarlitinib
CAS:Varlitinib (ASLAN001) is a potent, reversible, small molecule pan-EGFR inhibitor with IC50s of 7, 2, 4 nM for HER1, HER2 and HER4, respectively.Formula:C22H19ClN6O2SPurity:99.7%Color and Shape:SolidMolecular weight:466.94MS39N
CAS:<p>MS39N (compound 27) serves as the negative control for MS39, capable of binding to EGFR without causing its degradation.</p>Formula:C55H71ClFN9O7SMolecular weight:1056.73TrkA-IN-6
<p>TrkA-IN-6 (compound R48) is a hydrazone-based, selective inhibitor of the tropomyosin receptor kinase A (TrkA). It exhibits greater cytotoxicity towards U87 GBM cells compared to Temozolomide, with an IC50 of 68.99 μM.</p>Formula:C16H13N3O5Molecular weight:327.08552Anti-TrkB/NTRK2 Antibody
<p>Anti-TrkB/NTRK2 Antibody is a human-derived antibody produced in CHO cells, targeting TrkB. For the isotype control of Anti-TrkB/NTRK2 Antibody, refer to HumanIgG2kappa, Isotype Control.</p>Color and Shape:Odour LiquidAnti-ERBB3/HER3 (29Z6)
Anti-ERBB3/HER3 (29Z6) is an antibody inhibitor targeting human ERBB3/HER3.Color and Shape:Odour LiquidHER2-IN-14
CAS:HER2-IN-14 (Compound 34) is a potent inhibitor of HER2, achieving an inhibitory concentration (IC50) of 18 nM.Formula:C26H23ClF2N8O3Color and Shape:SolidMolecular weight:568.96PKG Substrate
CAS:PKG Substrate is selective for PKG, favors PKG Iα (Km=59µM) over PKG II (Km=305µM).Formula:C35H67N17O11Purity:98%Color and Shape:SolidMolecular weight:902.01Cetuximab (PBS)
Cetuximab (PBS) is a human IgG1 monoclonal antibody that inhibits the epidermal growth factor receptor (EGFR), with a dissociation constant (Kd) of 0.201 nM for EGFR as measured by the SPR method. It exhibits potent antitumor activity.Color and Shape:Odour LiquidEGFR-IN-76
CAS:EGFR-IN-76 is a potent EGFR inhibitor.Formula:C30H30ClFN6O2Purity:97.02% - 97.72%Color and Shape:SolidMolecular weight:561.05GIP, human
CAS:<p>Insulinotropic hormone from K-cells, binds GIP receptors, boosts insulin, affects lipids, and has antiapoptotic properties.</p>Formula:C226H338N60O66SPurity:98%Color and Shape:SolidMolecular weight:4983.6Istiratumab
CAS:Istiratumab (M-6495) is a bispecific antibody against IGF-1R/ErbB3 for cancer research, promoting receptor degradation.Color and Shape:LiquidValanafusp alfa
CAS:Valanafusp alfa (AGT-181) is a fusion protein targeting HIR and IDUA for MPS I research.Color and Shape:LiquidDSPE-PEG5000-GE11
DSPE-PEG5000-GE11 is a PEG compound composed of DSPE and the EGFR-targeting peptide (GE11). GE11 is applicable for cancer cells with EGFR overexpression. DSPE-PEG5000-GE11 is utilized in drug delivery.Color and Shape:Odour SolidJBJ-09-063 TFA
JBJ-09-063 TFA, an EGFR inhibitor selective for EGFR mutations, IC50s: 0.147-0.396 nM, blocks EGFR/Akt/ERK signaling, for EGFR-mutant lung cancer research.Formula:C33H30F4N4O5SColor and Shape:SolidMolecular weight:670.67BMS-777607
CAS:BMS-777607 is a Met-related inhibitor for c-Met, Axl, Ron and Tyro3.Formula:C25H19ClF2N4O4Purity:98.16% - 98.56%Color and Shape:SolidMolecular weight:512.89Ref: TM-T2658
2mg63.00€5mg90.00€10mg142.00€25mg265.00€50mg409.00€100mg727.00€200mg1,091.00€500mg1,636.00€Compound TPX-0046
CAS:Compound TPX-0046 is an inhibitor of RET. Compound TPX-0046 can inhibit the RET autophosphorylation. Compound TPX-0046 can be used for the research of cancer.Formula:C21H21FN6O3Purity:99.94%Color and Shape:SoildMolecular weight:424.43Duligotuzumab
CAS:Duligotuzumab is a dual-targeting anti-EGFR/HER3 mAb that blocks signaling and induces ADCC for tumors with poor prognosis.Purity:97.7% (SDS-PAGE); 96.3% (SEC-HPLC) - ≥95% (SDS-PAGE); 95.19% (SEC-HPLC)Color and Shape:LiquidJAK1/2/3 Inhibitor 1
CAS:JAK1/2/3 Inhibitor 1 is a potent protein kinase inhibitor.JAK1/2/3 Inhibitor 1 has antitumor activity that inhibits the growth of a variety of cancer cell linesFormula:C6H2Cl2N2SPurity:99.99%Color and Shape:SolidMolecular weight:205.06
