Tyrosine Kinase/Adaptors
Tyrosine kinase and adaptor inhibitors are compounds that target tyrosine kinases and their associated adaptor proteins, which play pivotal roles in cell signaling, growth, and differentiation. These inhibitors are essential tools in cancer research, as many tyrosine kinases are involved in the signaling pathways that drive tumor growth and metastasis. By inhibiting tyrosine kinases, these compounds can block critical signaling cascades, offering potential therapeutic strategies for various cancers and other diseases involving abnormal cell signaling. At CymitQuimica, we provide a comprehensive range of high-quality tyrosine kinase and adaptor inhibitors to support your research in oncology, molecular biology, and targeted therapy development.
Subcategories of "Tyrosine Kinase/Adaptors"
- ALK(135 products)
- CSF-1R(42 products)
- EGFR(561 products)
- Ephrin Receptor(25 products)
- FLT(89 products)
- Fibroblast Growth Factor Receptor (FGFR)(177 products)
- HER(5 products)
- Hck(3 products)
- IGF-1R(99 products)
- PDGFR(127 products)
- PYK2(7 products)
- Src(82 products)
- TAM Receptor(34 products)
- Tie-2(20 products)
- Trk receptor(53 products)
- Tyrosine Kinases(14 products)
- VEGFR(239 products)
- c-Fms(105 products)
- c-Kit(113 products)
- c-Met/HGFR(137 products)
- c-RET(61 products)
Show 13 more subcategories
Found 1045 products of "Tyrosine Kinase/Adaptors"
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Adimanebart
CAS:Amdokitug is a human-derived IgG1λ monoclonal antibody that acts as an inhibitor of MUSK.Color and Shape:LiquidIGF-I (24-41)
CAS:IGF-I (24-41) is a fragment of IGF-I, affecting GH activities with anabolic, antioxidant, anti-inflammatory, and cytoprotective properties.
Formula:C88H133N27O28Purity:98%Color and Shape:SolidMolecular weight:2017.16MS39N
CAS:MS39N (compound 27) serves as the negative control for MS39, capable of binding to EGFR without causing its degradation.Formula:C55H71ClFN9O7SMolecular weight:1056.73Varlitinib Tosylate
CAS:Varlitinib Tosylate is a selective and potent inhibitor of ErbB1(EGFR) and ErbB2(HER2).Formula:C36H35ClN6O8S3Purity:98%Color and Shape:SolidMolecular weight:811.34INSR agonist 1
INSR agonist 1, an insulin receptor (INSR) agonist, effectively elevates INSR pY1355/1361 levels and exhibits synergistic effects with insulin.Formula:C36H47BrN4O6Color and Shape:SolidMolecular weight:711.69CPF-7
CAS:CPF-7 (Caerulein precursor fragment), an insulinotropic peptide, promotes insulin secretion and drives epithelial-mesenchymal transition via Snai1 upregulationFormula:C118H193N33O32Color and Shape:SolidMolecular weight:2586Anti-ERBB3/HER3 (29Z6)
Anti-ERBB3/HER3 (29Z6) is an antibody inhibitor targeting human ERBB3/HER3.Color and Shape:Odour LiquidBMS-599626
CAS:BMS-599626 (AC480) has been used in trials studying the treatment of Cancer, Metastases, and HER2 or EGFR Expressing Advanced Solid Malignancies.Formula:C27H27FN8O3Purity:98.73%Color and Shape:SolidMolecular weight:530.55Nuzefatide
CAS:Nuzefatide is a peptide that binds to liver protein receptors.Formula:C105H162N32O27S3Color and Shape:SolidMolecular weight:2400.80ZIGIR
ZIGIR enables insulin-based sorting of pure alpha and beta cells, revealing zinc(II) in human delta cell granules.Formula:C39H40N6O3Purity:98.34% - 99.32%Color and Shape:SolidMolecular weight:640.77Opadotina
Opadotina, a small-molecule anvatabart opadotin, exhibits antineoplastic activity [1].Color and Shape:Odour SolidPF-04217903 phenolsulfonate
CAS:PF-04217903 phenolsulfonate is a potent ATP-competitive inhibitor of c-Met kinase (Ki of 4.8 nM for human c-Met).Formula:C25H22N8O5SPurity:98%Color and Shape:SolidMolecular weight:546.56EP26
EP26 is an orally active and potent inhibitor of EGFR and PD-L1, with IC50 values of 48.6 nM and 1.77 µM, respectively. It reduces the protein expression of p-EGFR and induces cell cycle arrest at the G0/G1 phase. EP26 shows potential for glioblastoma research.Formula:C42H42ClFN4O5Molecular weight:736.28278Zenocutuzumab
CAS:Zenocutuzumab (MCLA-128) is a humanized antibody targeting HER2, used for research on tumors driven by NRG1 gene rearrangement.Purity:97%Color and Shape:LiquidMolecular weight:145.76 kDaEGFR-IN-43
EGFR-IN-43 (17c) is a potent EGFR inhibitor with ER antagonist action, tamoxifen/endoxifen+gefitinib linkage, and strong anticancer activity.Formula:C50H55ClFN5O5Color and Shape:SolidMolecular weight:860.45IGF-I (30-41)
CAS:IGF-I (30-41) is amino acids 30 to 41 fragment of Insulin-like Growth Factor I (IGF-I).Formula:C51H83N19O19Purity:98%Color and Shape:SolidMolecular weight:1266.34(2S,4R)-DS89002333
(2S,4R)-DS89002333 is an enantiomer of DS89002333 and functions as an orally active PRKACA inhibitor, exhibiting an IC50 of 0.3 nM.Formula:C22H20ClF2N3O3Molecular weight:447.11613LDN-193189 2HCl
CAS:LDN-193189 2HCl inhibits BMP signaling (ALK1/2/3/6), IC50: 0.8-16.7 nM; selective over TGF-β by 200-fold in C2C12 cells.
Formula:C25H24Cl2N6Purity:99.78%Color and Shape:SolidMolecular weight:479.4SJF 1521
CAS:SJF 1521 is an EGFR degrader belonging to the PROTAC class that selectively degrades EGFR while preserving HER2.Formula:C57H61ClFN7O9SPurity:99.20%Color and Shape:SolidMolecular weight:1074.65PROTAC EGFR degrader 10
CAS:PROTAC EGF Rdegrader 10 (Compound B56) is a PROTAC degrader targeting the epidermal growth factor receptor (EGFR) with a DC50 of less than 100 nM. It binds to CRBN-DDB1 with a Ki of 37 nM and degrades EGFR, focal adhesion kinase (FAK), and RSK1, inhibiting the proliferation of BaF3 wild-type and EGFR mutants with an IC50 of less than 150 nM.Formula:C49H65ClN10O7SColor and Shape:SolidMolecular weight:973.62
