Tyrosine Kinase/Adaptors
Tyrosine kinase and adaptor inhibitors are compounds that target tyrosine kinases and their associated adaptor proteins, which play pivotal roles in cell signaling, growth, and differentiation. These inhibitors are essential tools in cancer research, as many tyrosine kinases are involved in the signaling pathways that drive tumor growth and metastasis. By inhibiting tyrosine kinases, these compounds can block critical signaling cascades, offering potential therapeutic strategies for various cancers and other diseases involving abnormal cell signaling. At CymitQuimica, we provide a comprehensive range of high-quality tyrosine kinase and adaptor inhibitors to support your research in oncology, molecular biology, and targeted therapy development.
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Subcategories of "Tyrosine Kinase/Adaptors"
ALK
CSF-1R
EGFR
Ephrin Receptor
FLT
Fibroblast Growth Factor Receptor (FGFR)
HER
Hck
IGF-1R
PDGFR
PYK2
Src
TAM Receptor
Tie-2
Trk receptor
Tyrosine Kinases
VEGFR
c-Fms
c-Kit
c-Met/HGFR
c-RET
Show 13 more subcategories
Products of "Tyrosine Kinase/Adaptors"
Tyrphostin AG 879
CAS:148741-30-4
Tyrphostin AG 879 (AG 879) effectively inhibits HER2/ErbB2 (IC50: 1 μM), 100- and 500-fold higher …
Formula:
C18H24N2OS
Purity:
99.05%
Color and Shape:
Solid
Molecular weight:
316.46
Ref: TM-T6712
| 5mg | 50.00 € | ||
| 10mg | 73.00 € | ||
| 25mg | 152.00 € | ||
| 50mg | 245.00 € | ||
| 100mg | 418.00 € | ||
| 1mL*10mM (DMSO) | 53.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
K02288
CAS:1431985-92-0
K 02288 is a novel small molecule inhibitor of ALK1/2/3/6.
Formula:
C20H20N2O4
Purity:
98% - 99.81%
Color and Shape:
Solid
Molecular weight:
352.38
Ref: TM-T1914
| 2mg | 44.00 € | ||
| 5mg | 61.00 € | ||
| 10mg | 101.00 € | ||
| 25mg | 160.00 € | ||
| 50mg | 274.00 € | ||
| 100mg | 403.00 € | ||
| 1mL*10mM (DMSO) | 64.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
BMS-794833
CAS:1174046-72-0
BMS-794833 is a potent ATP competitive inhibitor of Met/VEGFR2; a prodrug of BMS-817378.
Formula:
C23H15ClF2N4O3
Purity:
98% - 99.69%
Color and Shape:
Solid
Molecular weight:
468.84
Ref: TM-T2419
| 1mg | 41.00 € | ||
| 2mg | 57.00 € | ||
| 5mg | 92.00 € | ||
| 10mg | 152.00 € | ||
| 25mg | 296.00 € | ||
| 50mg | 533.00 € | ||
| 100mg | 754.00 € | ||
| 1mL*10mM (DMSO) | 94.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
PD168393
CAS:194423-15-9
PD168393 is an irreversible EGFR inhibitor (IC50: 0.70 nM), irreversibly alkylate Cys-773; inactive against PKC, …
Formula:
C17H13BrN4O
Purity:
99.13% - 99.7%
Color and Shape:
Solid
Molecular weight:
369.22
Ref: TM-T6932
| 1mg | 39.00 € | ||
| 2mg | 49.00 € | ||
| 5mg | 66.00 € | ||
| 10mg | 88.00 € | ||
| 25mg | 151.00 € | ||
| 50mg | 219.00 € | ||
| 100mg | 304.00 € | ||
| 1mL*10mM (DMSO) | 56.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
NS309
CAS:18711-16-5
NS309 activates SK/KCa2, IK/KCa3.1 (0.12-1.2 μM EC50, 10-90 nM EC50), and Kv11.1 channels; doesn't affect …
Formula:
C8H4Cl2N2O2
Purity:
95.87%
Color and Shape:
Solid
Molecular weight:
231.04
Ref: TM-T4612
| 5mg | 57.00 € | ||
| 10mg | 69.00 € | ||
| 25mg | 119.00 € | ||
| 50mg | 214.00 € | ||
| 100mg | 318.00 € | ||
| 200mg | 465.00 € | ||
| 500mg | 734.00 € | ||
| 1mL*10mM (DMSO) | 62.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Tepotinib hydrochloride(1 : x)
CAS:1103508-80-0
Tepotinib hydrochloride(1 : x) is an orally bioavailable, mesenchymal-epithelial transition (MET) TKI developed mainly for …
Formula:
C29H29ClN6O2
Purity:
99.81%
Color and Shape:
Solid
Molecular weight:
529.04
Ref: TM-T9601
| 1mg | 143.00 € | ||
| 5mg | 312.00 € | ||
| 10mg | 465.00 € | ||
| 25mg | 741.00 € | ||
| 50mg | 1,054.00 € | ||
| 1mL*10mM (DMSO) | 400.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
SAR131675
CAS:1433953-83-3
SAR131675 is a potent and selective VEGFR3 inhibitor with an IC50 of 23 nM.
Formula:
C18H22N4O4
Purity:
97.52% - 99.68%
Color and Shape:
Solid
Molecular weight:
358.39
Ref: TM-T6012
| 1mg | 36.00 € | ||
| 5mg | 72.00 € | ||
| 10mg | 111.00 € | ||
| 25mg | 221.00 € | ||
| 50mg | 337.00 € | ||
| 100mg | 504.00 € | ||
| 200mg | 606.00 € | ||
| 1mL*10mM (DMSO) | 85.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Cetuximab
CAS:205923-56-4
Cetuximab (C225) is a monoclonal antibody that is an inhibitor of human epidermal growth factor …
Formula:
C107H179N35O36S7
Purity:
100.00% - SDS-PAGE:98.4%；SEC-HPLC: 99.7%
Color and Shape:
Liquid
Molecular weight:
152 kDa
Ref: TM-T9905
| 1mg | 185.00 € | ||
| 2mg | 269.00 € | ||
| 5mg | 448.00 € | ||
| 10mg | 648.00 € | ||
| 25mg | 1,013.00 € | ||
| 50mg | 1,365.00 € | ||
| 100mg | 1,839.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Lenvatinib mesylate
CAS:857890-39-2
Lenvatinib mesylate (E7080 (mesylate)) is an oral and multi-targeted inhibitor of VEGFR1-3, FGFR1-4, PDGFR, KIT, …
Formula:
C22H23ClN4O7S
Purity:
99.03% - 99.79%
Color and Shape:
Solid
Molecular weight:
522.96
Ref: TM-T8541
| 10mg | 40.00 € | ||
| 25mg | 59.00 € | ||
| 50mg | 87.00 € | ||
| 100mg | 109.00 € | ||
| 200mg | 162.00 € | ||
| 500mg | 263.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Pacritinib
CAS:937272-79-2
Pacritinib (SB1518) (SB1518) is an effective and specific inhibitor of JAK2 and FLT3 (IC50: 23/22 …
Formula:
C28H32N4O3
Purity:
99.27% - ≥95%
Color and Shape:
Solid
Molecular weight:
472.58
Ref: TM-T6020
| 2mg | 40.00 € | ||
| 5mg | 59.00 € | ||
| 10mg | 96.00 € | ||
| 25mg | 148.00 € | ||
| 50mg | 222.00 € | ||
| 100mg | 368.00 € | ||
| 500mg | 866.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Baricitinib phosphate
CAS:1187595-84-1
Baricitinib phosphate (INCB028050) is a selective orally bioavailable JAK1/JAK2 inhibitor.
Formula:
C16H20N7O6PS
Purity:
98.87% - 99.68%
Color and Shape:
Solid
Molecular weight:
469.41
Ref: TM-T2360
| 5mg | 47.00 € | ||
| 10mg | 62.00 € | ||
| 25mg | 91.00 € | ||
| 50mg | 113.00 € | ||
| 100mg | 142.00 € | ||
| 500mg | 343.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Tie2 kinase inhibitor 1
CAS:948557-43-5
Tie2 kinase inhibitor 1 (Tie2 kinase inhibitor), an optimized compound of SB-203580, is selective to …
Formula:
C26H21N3O2S
Purity:
99.81%
Color and Shape:
Solid
Molecular weight:
439.53
Ref: TM-T6335
| 1mg | 66.00 € | ||
| 5mg | 149.00 € | ||
| 10mg | 223.00 € | ||
| 25mg | 400.00 € | ||
| 50mg | 603.00 € | ||
| 100mg | 828.00 € | ||
| 500mg | 1,669.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
SSR128129E
CAS:848318-25-2
SSR128129E (SSR) is an allosteric and orally-active FGFR1 inhibitor (IC50: 1.9 μM), but not affecting …
Formula:
C18H15N2O4·Na
Purity:
98.79% - ≥95%
Color and Shape:
Solid
Molecular weight:
346.31
Ref: TM-T6082
| 2mg | 40.00 € | ||
| 5mg | 61.00 € | ||
| 10mg | 88.00 € | ||
| 25mg | 155.00 € | ||
| 50mg | 275.00 € | ||
| 100mg | 432.00 € | ||
| 1mL*10mM (DMSO) | 77.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
AZD7507
CAS:1041852-85-0
AZD7507 is a CSF-1R inhibitor with an IC50 of 32 nM. AZD7507 has antitumor activity.
Formula:
C23H27FN6O3
Purity:
98.01% - 99.09%
Color and Shape:
Solid
Molecular weight:
454.5
Ref: TM-T14380
| 1mg | 51.00 € | ||
| 5mg | 112.00 € | ||
| 10mg | 164.00 € | ||
| 25mg | 295.00 € | ||
| 50mg | 426.00 € | ||
| 100mg | 593.00 € | ||
| 200mg | 801.00 € | ||
| 1mL*10mM (DMSO) | 129.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
ONO-7475
CAS:1646839-59-9
ONO-7475 is an inhibitor with high specificity for anexelekto and MER tyrosine kinase
Formula:
C32H26N4O6
Purity:
98.74%
Color and Shape:
Solid
Molecular weight:
562.57
Ref: TM-T8327
| 1mg | 62.00 € | ||
| 5mg | 135.00 € | ||
| 10mg | 209.00 € | ||
| 25mg | 353.00 € | ||
| 50mg | 525.00 € | ||
| 100mg | 738.00 € | ||
| 1mL*10mM (DMSO) | 167.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
GW788388
CAS:452342-67-5
GW788388 is a potent and selective inhibitor of ALK5, also inhibits TGF-(beta) type II receptor …
Formula:
C25H23N5O2
Purity:
98.03% - 98.79%
Color and Shape:
Solid
Molecular weight:
425.48
Ref: TM-T1800
| 5mg | 63.00 € | ||
| 10mg | 93.00 € | ||
| 25mg | 167.00 € | ||
| 50mg | 261.00 € | ||
| 100mg | 384.00 € | ||
| 500mg | 894.00 € | ||
| 1mL*10mM (DMSO) | 65.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Treprostinil Sodium
CAS:289480-64-4
Treprostinil Sodium (UT-15) is a potent DP1, IP and EP2 agonist (EC50: 0.6/1.9/6.2 nM).
Formula:
C23H33NaO5
Purity:
99.95%
Color and Shape:
Solid
Molecular weight:
412.5
Ref: TM-T5171
| 1mg | 51.00 € | ||
| 5mg | 96.00 € | ||
| 10mg | 138.00 € | ||
| 25mg | 268.00 € | ||
| 50mg | 434.00 € | ||
| 1mL*10mM (DMSO) | 96.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
PKI (5-24) Acetate(99534-03-9 free base)
PKI (5-24) Acetate is a high affinity PKA inhibitor (Ki = 2.3 nM).
Formula:
C96H152N32O33
Purity:
99.47%
Color and Shape:
Solid
Molecular weight:
2282.43
Ref: TM-TP1957L
| 1mg | 84.00 € | ||
| 5mg | 154.00 € | ||
| 10mg | 250.00 € | ||
| 25mg | 414.00 € | ||
| 50mg | 582.00 € | ||
| 100mg | 785.00 € | ||
| 200mg | 1,052.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
AG1557
CAS:189290-58-2
AG1557 (AG-1557) is an inhibitor of the epidermal growth factor receptor (EGFR) tyrosine kinase (pIC50: …
Formula:
C16H14IN3O2
Purity:
98.62% - 99.23%
Color and Shape:
Solid
Molecular weight:
407.21
Ref: TM-T2034
| 10mg | 48.00 € | ||
| 25mg | 81.00 € | ||
| 50mg | 118.00 € | ||
| 100mg | 182.00 € | ||
| 200mg | 273.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
XL092
CAS:2367004-54-2
XL092 (JUN04542) is an Axl Mer cMet KDR inhibitor for the treatment of Axl and …
Formula:
C29H25FN4O5
Purity:
99.51%
Color and Shape:
Solid
Molecular weight:
528.53
Ref: TM-T9052
| 2mg | 35.00 € | ||
| 5mg | 51.00 € | ||
| 10mg | 79.00 € | ||
| 25mg | 132.00 € | ||
| 50mg | 208.00 € | ||
| 100mg | 346.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
