Tyrosine Kinase/Adaptors
Tyrosine kinase and adaptor inhibitors are compounds that target tyrosine kinases and their associated adaptor proteins, which play pivotal roles in cell signaling, growth, and differentiation. These inhibitors are essential tools in cancer research, as many tyrosine kinases are involved in the signaling pathways that drive tumor growth and metastasis. By inhibiting tyrosine kinases, these compounds can block critical signaling cascades, offering potential therapeutic strategies for various cancers and other diseases involving abnormal cell signaling. At CymitQuimica, we provide a comprehensive range of high-quality tyrosine kinase and adaptor inhibitors to support your research in oncology, molecular biology, and targeted therapy development.
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Subcategories of "Tyrosine Kinase/Adaptors"
ALK
CSF-1R
EGFR
Ephrin Receptor
FLT
Fibroblast Growth Factor Receptor (FGFR)
HER
Hck
IGF-1R
PDGFR
PYK2
Src
TAM Receptor
Tie-2
Trk receptor
Tyrosine Kinases
VEGFR
c-Fms
c-Kit
c-Met/HGFR
c-RET
Show 13 more subcategories
Products of "Tyrosine Kinase/Adaptors"
ML347
CAS:1062368-49-3
ML347 (LDN 193719)(DN193719) is a highly specific ALK1/2 inhibitor ( IC50: 46/32 nM), and the …
Formula:
C22H16N4O
Purity:
98.3% - ≥95%
Color and Shape:
Solid
Molecular weight:
352.39
Ref: TM-T1943
| 2mg | 39.00 € | ||
| 5mg | 57.00 € | ||
| 10mg | 84.00 € | ||
| 25mg | 155.00 € | ||
| 50mg | 271.00 € | ||
| 100mg | 460.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
(S)-Afatinib
CAS:439081-18-2
(S)-Afatinib (BIBW2992) is an irreversible EGFR family inhibitor with IC50s of 0.5/0.4/10/14/1 nM for EGFRwt, …
Formula:
C24H25ClFN5O3
Purity:
100% - 99.96%
Color and Shape:
Off-White Solid
Molecular weight:
485.94
Ref: TM-T2303
| 1g | 64.00 € | ||
| 200mg | 36.00 € | ||
| 500mg | 50.00 € | ||
| 1mL*10mM (DMSO) | 34.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
E-4031
CAS:113559-13-0
E-4031 is a methanesulfonanilide class III antiarrhythmic agent that prolongs cardiac action potential duration by …
Formula:
C21H29Cl2N3O3S
Purity:
97.71% - 99.31%
Color and Shape:
Solid
Molecular weight:
474.44
Ref: TM-T7198
| 2mg | 45.00 € | ||
| 5mg | 66.00 € | ||
| 10mg | 94.00 € | ||
| 25mg | 213.00 € | ||
| 50mg | 383.00 € | ||
| 100mg | 570.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
H3B-6527
CAS:1702259-66-2
H3B-6527 Is a Potent and Selective Inhibitor of FGFR4 in FGF19-Driven Hepatocellular Carcinoma, with antineoplastic …
Formula:
C29H34Cl2N8O4
Purity:
97.45%
Color and Shape:
Solid
Molecular weight:
629.54
Ref: TM-T7738
| 1mg | 69.00 € | ||
| 5mg | 165.00 € | ||
| 10mg | 268.00 € | ||
| 25mg | 518.00 € | ||
| 50mg | 732.00 € | ||
| 100mg | 1,040.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
TX1-85-1
CAS:1603845-32-4
TX1-85-1: irreversible Her3 inhibitor (IC50: 23 nM), degrades Her3 protein, disrupts signaling, binds Cys721 covalently.
Formula:
C32H36N8O3
Purity:
98.12% - 98.12%
Color and Shape:
Solid
Molecular weight:
580.68
Ref: TM-T17182
| 1mg | 69.00 € | ||
| 5mg | 125.00 € | ||
| 10mg | 212.00 € | ||
| 25mg | 362.00 € | ||
| 50mg | 532.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
TAS0728
CAS:2088323-16-2
TAS0728 is a HER2 inhibitor, with antitumor activity
Formula:
C26H32N8O3
Purity:
97.78%
Color and Shape:
Solid
Molecular weight:
504.58
Ref: TM-T7819
| 1mg | 50.00 € | ||
| 5mg | 107.00 € | ||
| 10mg | 169.00 € | ||
| 25mg | 310.00 € | ||
| 50mg | 493.00 € | ||
| 100mg | 670.00 € | ||
| 200mg | 902.00 € | ||
| 1mL*10mM (DMSO) | 113.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Pyridostatin
CAS:1085412-37-8
Pyridostatin (RR82) is a synthetic small-molecule stabilizer of G-quadruplexes, a secondary structure of DNA that …
Formula:
C31H32N8O5
Purity:
98%
Color and Shape:
Solid
Molecular weight:
596.64
Ref: TM-T1899
| 1mg | 41.00 € | ||
| 5mg | 80.00 € | ||
| 10mg | 109.00 € | ||
| 25mg | 187.00 € | ||
| 50mg | 292.00 € | ||
| 1mL*10mM (DMSO) | 115.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
LM22A-4
CAS:37988-18-4
LM22A-4: BDNF mimetic, TrkB agonist, IC50=47 nM (fluorescence anisotropy).
Formula:
C15H21N3O6
Purity:
≥95%
Color and Shape:
Solid
Molecular weight:
339.34
Ref: TM-T7568
| 5mg | 46.00 € | ||
| 10mg | 78.00 € | ||
| 25mg | 149.00 € | ||
| 50mg | 253.00 € | ||
| 100mg | 444.00 € | ||
| 500mg | 975.00 € | ||
| 1mL*10mM (DMSO) | 51.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
WRG-28
CAS:1913291-02-7
WRG-28 is a potent and selective, allosteric discoidin domain receptor 2 (ddr2) inhibitor(IC50 : 230 …
Formula:
C21H18N2O5S
Purity:
97.21%
Color and Shape:
Solid
Molecular weight:
410.44
Ref: TM-T17258
| 1mg | 47.00 € | ||
| 5mg | 96.00 € | ||
| 10mg | 142.00 € | ||
| 25mg | 291.00 € | ||
| 50mg | 491.00 € | ||
| 100mg | 717.00 € | ||
| 1mL*10mM (DMSO) | 96.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
AD80
CAS:1384071-99-1
AD80, a multikinase inhibitor, inhibits RET, RAF, SRCand S6K, with greatly reduced mTOR activity.
Formula:
C22H19F4N7O
Purity:
100% - 99.9%
Color and Shape:
Solid
Molecular weight:
473.43
Ref: TM-T4301
| 1mg | 46.00 € | ||
| 2mg | 40.00 € | ||
| 5mg | 92.00 € | ||
| 10mg | 146.00 € | ||
| 25mg | 283.00 € | ||
| 50mg | 465.00 € | ||
| 100mg | 682.00 € | ||
| 200mg | 547.00 € | ||
| 500mg | 1,375.00 € | ||
| 1mL*10mM (DMSO) | 96.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Tyrphostin B44, (+) enantiomer
CAS:133550-37-5
Tyrphostin B44, (+) enantiomer is an inhibitor of epidermal growth factor receptor (EGFR) kinase with …
Formula:
C18H16N2O3
Purity:
97.18%
Color and Shape:
Solid
Molecular weight:
308.33
Ref: TM-T22450
| 1mg | 50.00 € | ||
| 2mg | 71.00 € | ||
| 5mg | 102.00 € | ||
| 10mg | 159.00 € | ||
| 25mg | 266.00 € | ||
| 50mg | 364.00 € | ||
| 100mg | 524.00 € | ||
| 200mg | 712.00 € | ||
| 1mL*10mM (DMSO) | 113.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
![5-phenylthieno[2,3-d]pyrimidin-4-amine](https://static.cymitquimica.com/products/TM/thumb/T50042.jpg)
5-phenylthieno[2,3-d]pyrimidin-4-amine
CAS:195193-10-3
5-phenylthieno[2,3-d]pyrimidin-4-amine is a heterocycle that inhibits enzymes like kinases, may treat diseases.
Formula:
C12H9N3S
Purity:
97%
Color and Shape:
Solid
Molecular weight:
227.29
Ref: TM-T50042
| 2mg | 44.00 € | ||
| 5mg | 62.00 € | ||
| 10mg | 92.00 € | ||
| 25mg | 141.00 € | ||
| 50mg | 204.00 € | ||
| 100mg | 307.00 € | ||
| 200mg | 439.00 € | ||
| 1mL*10mM (DMSO) | 62.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Tolimidone
CAS:41964-07-2
Tolimidone (NSC 314335) is a chemical compound which inhibits acid secretion in animal models and …
Formula:
C11H10N2O2
Purity:
99.85%
Color and Shape:
Solid
Molecular weight:
202.21
Ref: TM-T6896
| 5mg | 50.00 € | ||
| 10mg | 75.00 € | ||
| 25mg | 115.00 € | ||
| 50mg | 177.00 € | ||
| 100mg | 265.00 € | ||
| 1mL*10mM (DMSO) | 53.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
![N-((4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-5-(6-methylpyridin-2-yl)-1H-imidazol-2-yl)methyl)-2-bro…](https://static.cymitquimica.com/products/TM/thumb/T9837.jpg)
N-((4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-5-(6-methylpyridin-2-yl)-1H-imidazol-2-yl)methyl)-2-bromoaniline
CAS:1352608-94-6
Compound 12d is a potent ALK5 inhibitor with an IC50 of 7nM.
Formula:
C22H18BrN7
Purity:
99.27%
Color and Shape:
Solid
Molecular weight:
460.33
Ref: TM-T9837
| 1mg | 96.00 € | ||
| 5mg | 187.00 € | ||
| 10mg | 276.00 € | ||
| 25mg | 441.00 € | ||
| 50mg | 628.00 € | ||
| 100mg | 844.00 € | ||
| 200mg | 1,130.00 € | ||
| 1mL*10mM (DMSO) | 221.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
NRC-2694
CAS:936446-61-6
NRC-2694 is an antagonist of the epidermal growth factor receptor (EGFR). It has anti-cancer and …
Formula:
C24H26N4O3
Purity:
99.38%
Color and Shape:
Solid
Molecular weight:
418.49
Ref: TM-T16343
| 1mg | 82.00 € | ||
| 5mg | 155.00 € | ||
| 10mg | 241.00 € | ||
| 25mg | 409.00 € | ||
| 50mg | 542.00 € | ||
| 100mg | 780.00 € | ||
| 200mg | 1,034.00 € | ||
| 1mL*10mM (DMSO) | 170.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
R112
CAS:575474-82-7
R112 ((E)-Elafibranor) is an ATP-competitive inhibitor of Syk kinase.
Formula:
C16H13FN4O2
Purity:
99.06% - 99.84%
Color and Shape:
Solid
Molecular weight:
312.3
Ref: TM-T3185
| 1mg | 39.00 € | ||
| 2mg | 52.00 € | ||
| 5mg | 84.00 € | ||
| 10mg | 125.00 € | ||
| 25mg | 219.00 € | ||
| 50mg | 330.00 € | ||
| 100mg | 489.00 € | ||
| 200mg | 396.00 € | ||
| 500mg | 1,008.00 € | ||
| 1mL*10mM (DMSO) | 93.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
RepSox
CAS:446859-33-2
RepSox (ALK5 Inhibitor II) is a TGFβR-1/ALK5 inhibitor that selectively inhibits the binding of ATP …
Formula:
C17H13N5
Purity:
98.8% - 99.62%
Color and Shape:
Solid
Molecular weight:
287.32
Ref: TM-T6337
| 1mg | 35.00 € | ||
| 2mg | 47.00 € | ||
| 5mg | 71.00 € | ||
| 10mg | 88.00 € | ||
| 25mg | 121.00 € | ||
| 50mg | 170.00 € | ||
| 100mg | 250.00 € | ||
| 500mg | 618.00 € | ||
| 1mL*10mM (DMSO) | 72.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Theliatinib
CAS:1353644-70-8
Theliatinib: potent, selective EGFR inhibitor, anti-tumor; Ki=0.05 nM (EGFR), IC50=3 nM (EGFR), 22 nM (T790M/L858R).
Formula:
C25H26N6O2
Purity:
99.67%
Color and Shape:
Solid
Molecular weight:
442.51
Ref: TM-T7322
| 1mg | 52.00 € | ||
| 5mg | 142.00 € | ||
| 10mg | 222.00 € | ||
| 25mg | 368.00 € | ||
| 50mg | 553.00 € | ||
| 100mg | 757.00 € | ||
| 1mL*10mM (DMSO) | 156.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Entrectinib
CAS:1108743-60-7
Entrectinib (RXDX-101) is an orally Trk, ROS1, and ALK inhibitor. Entrectinib exhibits antitumor activity. Cost-effective …
Formula:
C31H34F2N6O2
Purity:
98.03% - 99.61%
Color and Shape:
Solid
Molecular weight:
560.64
Ref: TM-T3678
| 2mg | 41.00 € | ||
| 5mg | 59.00 € | ||
| 10mg | 87.00 € | ||
| 25mg | 109.00 € | ||
| 50mg | 165.00 € | ||
| 100mg | 276.00 € | ||
| 500mg | 677.00 € | ||
| 1mL*10mM (DMSO) | 69.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Tanshinone IIA
CAS:568-72-9
Tanshinone IIA (Tanshinone B) is a natural diterpene quinone. Tanshinone IIA has anti-inflammatory, antioxidant activities. …
Formula:
C19H18O3
Purity:
100% - 99.54%
Color and Shape:
Cherry Crystal
Molecular weight:
294.34
Ref: TM-T2906
| 20mg | 54.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
