Tyrosine Kinase/Adaptors
Tyrosine kinase and adaptor inhibitors are compounds that target tyrosine kinases and their associated adaptor proteins, which play pivotal roles in cell signaling, growth, and differentiation. These inhibitors are essential tools in cancer research, as many tyrosine kinases are involved in the signaling pathways that drive tumor growth and metastasis. By inhibiting tyrosine kinases, these compounds can block critical signaling cascades, offering potential therapeutic strategies for various cancers and other diseases involving abnormal cell signaling. At CymitQuimica, we provide a comprehensive range of high-quality tyrosine kinase and adaptor inhibitors to support your research in oncology, molecular biology, and targeted therapy development.
Subcategories of "Tyrosine Kinase/Adaptors"
- ALK(137 products)
- CSF-1R(42 products)
- EGFR(581 products)
- Ephrin Receptor(25 products)
- FLT(86 products)
- Fibroblast Growth Factor Receptor (FGFR)(180 products)
- HER(6 products)
- Hck(3 products)
- IGF-1R(102 products)
- PDGFR(129 products)
- PYK2(7 products)
- Src(82 products)
- TAM Receptor(34 products)
- Tie-2(20 products)
- Trk receptor(56 products)
- Tyrosine Kinases(8 products)
- VEGFR(242 products)
- c-Fms(108 products)
- c-Kit(117 products)
- c-Met/HGFR(144 products)
- c-RET(61 products)
Show 13 more subcategories
Found 1041 products of "Tyrosine Kinase/Adaptors"
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PP2
CAS:PP2 (AG 1879,AGL 1879) is a effective inhibitor of Lck/Fyn (IC50:4/5 nM) , ~100-fold less potent to EGFR, inactive for ZAP-70, PKA and JAK2.Formula:C15H16ClN5Purity:98% - 98.21%Color and Shape:White SolidMolecular weight:301.77Ref: TM-T6266
2mg44.00€5mg65.00€1mL*10mM (DMSO)71.00€10mg110.00€25mg178.00€50mg304.00€100mg482.00€200mg687.00€Tyrphostin AG30
CAS:Tyrphostin AG30 (AG30) (AG30) is a potent protein tyrosine kinases (PTK) inhibitor.Formula:C10H7NO4Purity:99.02%Color and Shape:SolidMolecular weight:205.17PD-161570
CAS:PD-161570 is a potent and ATP-competitive human FGF-1 receptor inhibitor with an IC50 of 39.9 nM and a Ki of 42 nM.Formula:C26H35Cl2N7OPurity:99.92%Color and Shape:SolidMolecular weight:532.51Ref: TM-T23127
1mg34.00€5mg96.00€1mL*10mM (DMSO)118.00€10mg141.00€25mg289.00€50mg465.00€100mg662.00€200mg888.00€Derazantinib dihydrochloride
CAS:Derazantinib, a multi-kinase inhibitor targeting FGFR, benefits FGFR2-positive iCCA; its dihydrochloride form is a salt variant.Formula:C29H31Cl2FN4OColor and Shape:SolidMolecular weight:541.49Almonertinib
CAS:Almonertinib (HS-10296) is an inhibitor of EGFR activation mutation and tolerant mutation of EGFR T790M, which has only limited activity against wild-type EGFR.Formula:C30H35N7O2Purity:99.99%Color and Shape:SolidMolecular weight:525.64Ref: TM-T5462
1mg94.00€5mg187.00€1mL*10mM (DMSO)235.00€10mg295.00€25mg497.00€50mg717.00€100mg982.00€500mg1,998.00€Lazertinib
CAS:Lazertinib (GNS-1480) is a potent, selective, irreversible EGFR-TKI; IC50: 1.7-76 nM for various EGFR mutations.Formula:C30H34N8O3Purity:98.7% - 99.90%Color and Shape:SolidMolecular weight:554.64Ref: TM-T4485
1mg46.00€2mg59.00€5mg96.00€1mL*10mM (DMSO)104.00€10mg130.00€25mg215.00€50mg309.00€100mg444.00€200mg655.00€β-Hydroxyisovalerylshikonin
CAS:Beta-Hydroxyisovalerylshikonin is an inhibitor of protein-tyrosine kinases such as v-Src and EGFR, and has been shown to induce apoptosis in several human tumorFormula:C21H24O7Purity:98.16%Color and Shape:SolidMolecular weight:388.41PKG drug G1
CAS:PKG drug G1 targets PKG Iα C42. PKG drug G1 can couple to vasodilation and blood pressure lowering by a C42 PKG Iα-independent mechanism.Formula:C13H11N3OSPurity:97.57% - 97.67%Color and Shape:SolidMolecular weight:257.31Masitinib
CAS:Masitinib (AB1010) is a tyrosine-kinase inhibitor used in the treatment of mast cell tumors in animals, specifically dogs.Formula:C28H30N6OSPurity:97.56% - >99.99%Color and Shape:SolidMolecular weight:498.64VU6015929
CAS:VU6015929 is an inhibitor of active dual discoidin domain receptor 1/2 (DDR1/2)( IC50s of 4.67 nM and 7.39 nM, respectively).Formula:C24H19F4N5O2Purity:97.07% - 99.96%Color and Shape:SolidMolecular weight:485.43Ref: TM-T7862
1mg66.00€5mg133.00€1mL*10mM (DMSO)142.00€10mg200.00€25mg333.00€50mg469.00€100mg632.00€200mg852.00€PKI 14-22 amide, myristoylated Acetate
PKI 14-22 amide, myristoylated Acetate inhibit cAMP-dependent protein kinase (PKA) and blocks hyperalgesia produced by spinal administration of 8-bromo-cAMP.Formula:C55H104N20O14Purity:96.34%Color and Shape:SolidMolecular weight:1269.54Ref: TM-T21983L
1mg167.00€5mg363.00€10mg538.00€1mL*10mM (DMSO)695.00€25mg800.00€50mg1,071.00€100mg1,449.00€Sotuletinib
CAS:Sotuletinib (BLZ945) is an orally active, effective and specific CSF-1R inhibitor, >1000-fold selective against its closest receptor tyrosine kinase homologs.Formula:C20H22N4O3SPurity:97.43% - 99.82%Color and Shape:SolidMolecular weight:398.48Ref: TM-T6119
1mg34.00€5mg74.00€1mL*10mM (DMSO)82.00€10mg105.00€25mg163.00€50mg205.00€100mg358.00€500mg822.00€Bafetinib
CAS:Bafetinib (INNO-406): Dual Bcr-Abl/Lyn inhibitor; IC50: 5.8/19 nM; ineffective against T315I mutant, less on c-Kit/PDGFR.Formula:C30H31F3N8OPurity:94.16% - 99.68%Color and Shape:SolidMolecular weight:576.62Ref: TM-T6311
1mg34.00€2mg49.00€5mg74.00€1mL*10mM (DMSO)95.00€10mg98.00€25mg150.00€50mg178.00€100mg333.00€200mg432.00€Linsitinib
CAS:OSI-906 (Linsitinib) is an oral inhibitor of IGF-1R with anti-cancer properties, potentially halting tumor growth and inducing cell death.Formula:C26H23N5OPurity:99.71% - ≥95%Color and Shape:SolidMolecular weight:421.49DMH-1
CAS:DMH-1 is a BMP inhibitor that inhibits ALK1, ALK2, ALK3 and ALK6. DMH-1 promotes pluripotent stem cell differentiation. Cost-effective and quality-assured.
Formula:C24H20N4OPurity:98% - 99.92%Color and Shape:SolidMolecular weight:380.44Tyrphostin AG 879
CAS:Tyrphostin AG 879 (AG 879) effectively inhibits HER2/ErbB2 (IC50: 1 μM), 100- and 500-fold higher selective to ErbB2 than EGFR and PDGFR.Formula:C18H24N2OSPurity:99.05%Color and Shape:SolidMolecular weight:316.46MAZ51
CAS:MAZ51 is a VEGFR-3 (Flt-4) tyrosine kinase inhibitor.Formula:C21H18N2OPurity:98.53%Color and Shape:SolidMolecular weight:314.38Tyrphostin 23
CAS:Tyrphostin 23 (AG18) inhibits EGFR with IC50 of 35 μM.Formula:C10H6N2O2Purity:99.7% - 99.86%Color and Shape:Yellow-Tan SolidMolecular weight:186.17SU5205
CAS:SU5205 is a VEGFR2 inhibitor.
Formula:C15H10FNOPurity:99.62% - 99.67%Color and Shape:SolidMolecular weight:239.242-D08
CAS:2-D08 is a synthetic flavone that inhibits sumoylation, also inhibits Axl with an IC50 of 0.49 nM.2-D08 showed anti-aggregatory and neuroprotective effect.Formula:C15H10O5Purity:98.58% - 98.95%Color and Shape:SolidMolecular weight:270.24Ref: TM-T7379
2mg39.00€5mg54.00€1mL*10mM (DMSO)59.00€10mg93.00€25mg170.00€50mg268.00€100mg447.00€200mg650.00€
