Tyrosine Kinase/Adaptors
Tyrosine kinase and adaptor inhibitors are compounds that target tyrosine kinases and their associated adaptor proteins, which play pivotal roles in cell signaling, growth, and differentiation. These inhibitors are essential tools in cancer research, as many tyrosine kinases are involved in the signaling pathways that drive tumor growth and metastasis. By inhibiting tyrosine kinases, these compounds can block critical signaling cascades, offering potential therapeutic strategies for various cancers and other diseases involving abnormal cell signaling. At CymitQuimica, we provide a comprehensive range of high-quality tyrosine kinase and adaptor inhibitors to support your research in oncology, molecular biology, and targeted therapy development.
Subcategories of "Tyrosine Kinase/Adaptors"
- ALK(137 products)
- CSF-1R(42 products)
- EGFR(581 products)
- Ephrin Receptor(25 products)
- FLT(86 products)
- Fibroblast Growth Factor Receptor (FGFR)(180 products)
- HER(6 products)
- Hck(3 products)
- IGF-1R(102 products)
- PDGFR(129 products)
- PYK2(7 products)
- Src(82 products)
- TAM Receptor(34 products)
- Tie-2(20 products)
- Trk receptor(56 products)
- Tyrosine Kinases(8 products)
- VEGFR(242 products)
- c-Fms(108 products)
- c-Kit(117 products)
- c-Met/HGFR(144 products)
- c-RET(61 products)
Show 13 more subcategories
Found 1041 products of "Tyrosine Kinase/Adaptors"
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AMG-47a
CAS:AMG-47a inhibits Lck, T cell growth, and degrades KRAS oncoprotein, affecting EGFP-KRASG12V but not EGFP.Formula:C29H28F3N5O2Purity:98%Color and Shape:SolidMolecular weight:535.56CEP-40783
CAS:CEP-40783 (RXDX-106) is an effective, specific and orally active AXL/c-Met inhibitor (IC50: 7/12 nM). It also inhibits MER and TYRO3 (IC50: 29/19 nM).
Formula:C31H26F2N4O6Purity:99.76% - 99.84%Color and Shape:SolidMolecular weight:588.56Oritinib mesylate
CAS:Oritinib mesylate (SH-1028), an oral pyrimidine EGFR blocker with 18 nM IC50, targets both sensitive and T790M resistant mutations.Formula:C32H41N7O5SColor and Shape:SolidMolecular weight:635.78Dacomitinib hydrate
CAS:Dacomitinib hydrate (PF 299804) is a highly selective and second-generation small-molecule inhibitor of the pan-epidermal growth factor receptor family ofFormula:C24H27ClFN5O3Purity:99.52%Color and Shape:SolidMolecular weight:487.96Ref: TM-T19965
5mg48.00€1mL*10mM (DMSO)57.00€10mg75.00€25mg100.00€50mg133.00€100mg200.00€200mg295.00€PD153035 hydrochloride
CAS:PD153035 hydrochloride (ZM 252868) is a effective and selective inhibitor of EGFR; few influence against FGFR, PGDFR, InsR, CSF-1, and Src.
Formula:C16H15BrClN3O2Purity:99.39% - ≥95%Color and Shape:SolidMolecular weight:396.67Canertinib
CAS:Canertinib (CI-1033), a pan-erbB inhibitor, effectively targets esophageal cancer in vitro/vivo, altering metabolism and reducing growth and hypoxia.Formula:C24H25ClFN5O3Purity:98% - >99.99%Color and Shape:White Or Similar To White Crystalline PowderMolecular weight:485.94Theliatinib tartrate
CAS:Theliatinib: oral EGFR blocker, Ki 0.05 nM, IC50 3 nM (wild-type), 22 nM (T790M/L858R), >50x kinase selectivity.Formula:C29H32N6O8Color and Shape:SolidMolecular weight:592.6lavendustin C
CAS:lavendustin C (NSC 666251) is a potent inhibitor of epidermal growth factor (EGF) receptor-associated tyrosine kinase.Formula:C14H13NO5Purity:98.06%Color and Shape:Yellow To Tan PowderMolecular weight:275.26Ref: TM-T4185
1mg42.00€2mg55.00€1mL*10mM (DMSO)90.00€5mg93.00€10mg152.00€25mg330.00€50mg492.00€100mg707.00€PF 477736
CAS:PF 477736 (PF-736,PF-00477736) is a specifc, effective and ATP-competitive Chk1 inhibitor (Ki: 0.49 nM ) and also inhibits FGFR3, Aurora-A, VEGFR2, Flt3, Fms (Formula:C22H25N7O2Purity:97.58% - 99.94%Color and Shape:SolidMolecular weight:419.48G5-7
CAS:G5-7 is an oral JAK2 inhibitor targeting EGFR/STAT3 phosphorylation with potential for glioma research.Formula:C22H19F2NO3Purity:97.3%Color and Shape:SolidMolecular weight:383.39Ref: TM-T8742
1mg35.00€5mg71.00€1mL*10mM (DMSO)78.00€10mg96.00€25mg172.00€50mg248.00€100mg348.00€200mg470.00€WHI-P154
CAS:WHI-P154 (Jak3 inhibitor ii) is a potent JAK3 inhibitor.Formula:C16H14BrN3O3Purity:98% - 99.67%Color and Shape:SolidMolecular weight:376.2AG-494
CAS:AG-494 (Tyrphostin B48) is an inhibitor of epidermal growth factor receptor kinase.Formula:C16H12N2O3Purity:98.69%Color and Shape:SolidMolecular weight:280.28Neratinib
CAS:Neratinib (HKI-272) (HKI-272) is an orally available, irreversible tyrosine kinase inhibitor for HER2 and EGFR (IC50: 59/92 nM), respectively.Formula:C30H29ClN6O3Purity:96.17% - 99.85%Color and Shape:SolidMolecular weight:557.04CH7057288
CAS:CH7057288 is an effective and selective TRK inhibitor with an IC50 value of 1.1 nM, 7.8 nM and 5.1 nM for TRKA, TRKB and TRKC, respectively.Formula:C32H31N3O5SPurity:99.92%Color and Shape:SolidMolecular weight:569.67Osimertinib mesylate
CAS:Osimertinib mesylate (AZD-9291 mesylate) is an EGFR third-generation inhibitor. Osimertinib mesylate has antitumor activity. Cost-effective and quality-assured.
Formula:C29H37N7O5SPurity:99.46% - >99.99%Color and Shape:SolidMolecular weight:595.71Trastuzumab
CAS:Trastuzumab is a humanized monoclonal antibody for patients with invasive breast cancers that overexpress HER2.Purity:97.1% (SDS-PAGE); 99.2% (SEC-HPLC) - SDS-PAGE: 97.1%；SEC-HPLC: 99.2%Color and Shape:LiquidMolecular weight:145.36 kDaNazartinib
CAS:Nazartinib (EGF816) (EGF816, NVS-816) is a covalent, irreversible, mutant-selective EGFR inhibitor that has nanomolar inhibitory potency against activating mt (Formula:C26H31ClN6O2Purity:98.63% - ≥95%Color and Shape:Solid PowderMolecular weight:495.02Ref: TM-T3506
1mg37.00€5mg79.00€1mL*10mM (DMSO)87.00€10mg119.00€25mg187.00€50mg354.00€100mg528.00€500mg1,159.00€ENMD-2076
CAS:ENMD-2076, a multi-targeted kinase inhibitor, has specific activity against Aurora A, Flt3, KDR/VEGFR2, Flt4/VEGFR3, FGFR1, FGFR2, Src, PDGFRα.Formula:C21H25N7Purity:97.63% - ≥95%Color and Shape:SolidMolecular weight:375.47PD153035
CAS:PD153035 (NSC-669364) hydrochloride is an effective and selective inhibitor of EGFR (Ki/IC50: 5.2/29 pM, in cell-free assays); little inhibitory against FGFR,Formula:C16H14BrN3O2Purity:98.47% - 99.29%Color and Shape:SolidMolecular weight:360.21ML167
CAS:ML167 (CID44968231) is a highly selective Cdc2-like kinase 4 (Clk4) inhibitor.
Formula:C19H17N3O3Purity:99.82% - >99.99%Color and Shape:SolidMolecular weight:335.36
