Tyrosine Kinase/Adaptors
Tyrosine kinase and adaptor inhibitors are compounds that target tyrosine kinases and their associated adaptor proteins, which play pivotal roles in cell signaling, growth, and differentiation. These inhibitors are essential tools in cancer research, as many tyrosine kinases are involved in the signaling pathways that drive tumor growth and metastasis. By inhibiting tyrosine kinases, these compounds can block critical signaling cascades, offering potential therapeutic strategies for various cancers and other diseases involving abnormal cell signaling. At CymitQuimica, we provide a comprehensive range of high-quality tyrosine kinase and adaptor inhibitors to support your research in oncology, molecular biology, and targeted therapy development.
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Subcategories of "Tyrosine Kinase/Adaptors"
ALK
CSF-1R
EGFR
Ephrin Receptor
FLT
Fibroblast Growth Factor Receptor (FGFR)
HER
Hck
IGF-1R
PDGFR
PYK2
Src
TAM Receptor
Tie-2
Trk receptor
Tyrosine Kinases
VEGFR
c-Fms
c-Kit
c-Met/HGFR
c-RET
Show 13 more subcategories
Products of "Tyrosine Kinase/Adaptors"
AZ304
CAS:942507-42-8
AZ304 is an ATP-competitive dual BRAF kinase inhibitor, potently inhibits BRAF (WT), BRAF (V600E), and …
Formula:
C27H25N5O2
Purity:
99.83%
Color and Shape:
Solid
Molecular weight:
451.52
Ref: TM-T5172
| 10mg | 41.00 € | ||
| 25mg | 63.00 € | ||
| 50mg | 93.00 € | ||
| 100mg | 150.00 € | ||
| 1mL*10mM (DMSO) | 43.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Gefitinib-based PROTAC 3
CAS:2230821-27-7
Gefitinib-PROTAC 3 degrades EGFR in cancer cells; DC50s: 11.7 nM (HCC827) and 22.3 nM (H3255).
Formula:
C47H57ClFN7O8S
Purity:
97.29% - 98.25%
Color and Shape:
Solid
Molecular weight:
934.51
Ref: TM-T5437
| 2mg | 44.00 € | ||
| 5mg | 61.00 € | ||
| 10mg | 101.00 € | ||
| 25mg | 168.00 € | ||
| 50mg | 248.00 € | ||
| 100mg | 358.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Almonertinib
CAS:1899921-05-1
Almonertinib (HS-10296) is an inhibitor of EGFR activation mutation and tolerant mutation of EGFR T790M, …
Formula:
C30H35N7O2
Purity:
99.99%
Color and Shape:
Solid
Molecular weight:
525.64
Ref: TM-T5462
| 1mg | 88.00 € | ||
| 5mg | 193.00 € | ||
| 10mg | 305.00 € | ||
| 25mg | 514.00 € | ||
| 50mg | 739.00 € | ||
| 100mg | 1,016.00 € | ||
| 500mg | 2,070.00 € | ||
| 1mL*10mM (DMSO) | 248.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Merestinib
CAS:1206799-15-6
Merestinib (LY2801653) is an orally available, small molecule inhibitor of the proto-oncogene c-Met (Ki: 2 …
Formula:
C30H22F2N6O3
Purity:
95% - 99.56%
Color and Shape:
Solid
Molecular weight:
552.53
Ref: TM-T3455
| 1mg | 49.00 € | ||
| 2mg | 71.00 € | ||
| 5mg | 106.00 € | ||
| 10mg | 145.00 € | ||
| 25mg | 255.00 € | ||
| 50mg | 426.00 € | ||
| 100mg | 607.00 € | ||
| 200mg | 495.00 € | ||
| 500mg | 1,239.00 € | ||
| 1mL*10mM (DMSO) | 126.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Sotuletinib
CAS:953769-46-5
Sotuletinib (BLZ945) is an orally active, effective and specific CSF-1R inhibitor, >1000-fold selective against its …
Formula:
C20H22N4O3S
Purity:
97.43% - 99.82%
Color and Shape:
Solid
Molecular weight:
398.48
Ref: TM-T6119
| 1mg | 37.00 € | ||
| 5mg | 78.00 € | ||
| 10mg | 109.00 € | ||
| 25mg | 169.00 € | ||
| 50mg | 213.00 € | ||
| 100mg | 370.00 € | ||
| 500mg | 848.00 € | ||
| 1mL*10mM (DMSO) | 87.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
SU5408
CAS:15966-93-5
SU5408 (VEGFR2 Kinase Inhibitor I) is a potent, cell-permeable inhibitor of the VEGFR2 kinase.
Formula:
C18H18N2O3
Purity:
99.09%
Color and Shape:
Solid
Molecular weight:
310.35
Ref: TM-T4026
| 1mg | 69.00 € | ||
| 5mg | 184.00 € | ||
| 10mg | 277.00 € | ||
| 25mg | 508.00 € | ||
| 50mg | 686.00 € | ||
| 100mg | 886.00 € | ||
| 500mg | 1,748.00 € | ||
| 1mL*10mM (DMSO) | 205.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Desmethylanethol trithione
CAS:18274-81-2
Desmethylanethol trithione (ADT-OH), a synthetic H2S donor, modulates tPA effects, reduces stroke damage, and improves …
Formula:
C9H6OS3
Purity:
98.05% - 98.19%
Color and Shape:
Solid
Molecular weight:
226.34
Ref: TM-T3560
| 10mg | 39.00 € | ||
| 25mg | 63.00 € | ||
| 50mg | 93.00 € | ||
| 100mg | 151.00 € | ||
| 200mg | 217.00 € | ||
| 1mL*10mM (DMSO) | 34.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Semaxinib
CAS:204005-46-9
Semaxinib (SU5416): potent VEGFR2 inhibitor, 20x more selective over PDGFRβ, not active on InsR/EGFR/FGFR, blocks …
Formula:
C15H14N2O
Purity:
99.84%
Color and Shape:
Yellow To Yellow Orange
Molecular weight:
238.28
Ref: TM-T2064
| 5mg | 52.00 € | ||
| 10mg | 66.00 € | ||
| 25mg | 117.00 € | ||
| 50mg | 164.00 € | ||
| 100mg | 220.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Linsitinib
CAS:867160-71-2
OSI-906 (Linsitinib) is an oral inhibitor of IGF-1R with anti-cancer properties, potentially halting tumor growth …
Formula:
C26H23N5O
Purity:
98.98% - ≥95%
Color and Shape:
Solid
Molecular weight:
421.49
Ref: TM-T6017
| 2mg | 39.00 € | ||
| 5mg | 56.00 € | ||
| 10mg | 80.00 € | ||
| 25mg | 114.00 € | ||
| 50mg | 162.00 € | ||
| 100mg | 217.00 € | ||
| 1mL*10mM (DMSO) | 64.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
CH5424802 analog
CAS:1256577-71-5
CH5424802 analog is a selective ALK inhibitor capable of blocking the resistant gatekeeper mutant.
Formula:
C28H30N4O2
Purity:
98.96%
Color and Shape:
Solid
Molecular weight:
454.56
Ref: TM-T9224
| 1mg | 131.00 € | ||
| 5mg | 287.00 € | ||
| 10mg | 430.00 € | ||
| 25mg | 709.00 € | ||
| 50mg | 996.00 € | ||
| 100mg | 1,347.00 € | ||
| 200mg | 1,042.00 € | ||
| 1mL*10mM (DMSO) | 343.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
DMH-1
CAS:1206711-16-1
DMH-1 is a BMP inhibitor that inhibits ALK1, ALK2, ALK3 and ALK6. DMH-1 promotes pluripotent …
Formula:
C24H20N4O
Purity:
98% - 99.92%
Color and Shape:
Solid
Molecular weight:
380.44
Ref: TM-T1942
| 5mg | 62.00 € | ||
| 10mg | 96.00 € | ||
| 25mg | 162.00 € | ||
| 50mg | 277.00 € | ||
| 100mg | 428.00 € | ||
| 500mg | 917.00 € | ||
| 1mL*10mM (DMSO) | 69.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Entospletinib
CAS:1229208-44-9
Entospletinib (GS-9973) (IC50= 7.7 nM)is a specific Syk inhibitor, which is orally bioavailable.
Formula:
C23H21N7O
Purity:
98.2% - 99.51%
Color and Shape:
Solid
Molecular weight:
411.46
Ref: TM-T6101
| 1mg | 38.00 € | ||
| 2mg | 49.00 € | ||
| 5mg | 80.00 € | ||
| 10mg | 95.00 € | ||
| 25mg | 171.00 € | ||
| 50mg | 253.00 € | ||
| 100mg | 407.00 € | ||
| 200mg | 605.00 € | ||
| 1mL*10mM (DMSO) | 89.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Pexmetinib
CAS:945614-12-0
Pexmetinib (ARRY-614) is an orally bioavailable dual p38 MAPK/Tie-2 inhibitor.Cost-effective and quality-assured.
Formula:
C31H33FN6O3
Purity:
98.41% - 99.66%
Color and Shape:
Solid
Molecular weight:
556.63
Ref: TM-T6934
| 2mg | 58.00 € | ||
| 5mg | 95.00 € | ||
| 10mg | 151.00 € | ||
| 25mg | 296.00 € | ||
| 50mg | 501.00 € | ||
| 100mg | 558.00 € | ||
| 1mL*10mM (DMSO) | 119.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
ZM 306416
CAS:690206-97-4
ZM 306416 (CB 676475), a VEGFR1 inhibitor (IC50: 0.33 μM), can also inhibit EGFR (IC50 …
Formula:
C16H13ClFN3O2
Purity:
99.31% - ≥95%
Color and Shape:
Solid
Molecular weight:
333.74
Ref: TM-T1754
| 5mg | 46.00 € | ||
| 10mg | 68.00 € | ||
| 25mg | 132.00 € | ||
| 50mg | 203.00 € | ||
| 100mg | 325.00 € | ||
| 1mL*10mM (DMSO) | 51.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Vatalanib free base
CAS:212141-54-3
Vatalanib is a VEGFR2/KDR inhibitor (IC50: 37 nM).
Formula:
C20H15ClN4
Purity:
99.52%
Color and Shape:
Solid
Molecular weight:
346.81
Ref: TM-T17219
| 5mg | 47.00 € | ||
| 10mg | 69.00 € | ||
| 25mg | 114.00 € | ||
| 50mg | 176.00 € | ||
| 100mg | 259.00 € | ||
| 500mg | 630.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
AMG-47a
CAS:882663-88-9
AMG-47a inhibits Lck, T cell growth, and degrades KRAS oncoprotein, affecting EGFP-KRASG12V but not EGFP.
Formula:
C29H28F3N5O2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
535.56
Ref: TM-T7123
| 1mg | 45.00 € | ||
| 5mg | 96.00 € | ||
| 10mg | 149.00 € | ||
| 25mg | 244.00 € | ||
| 50mg | 362.00 € | ||
| 100mg | 532.00 € | ||
| 1mL*10mM (DMSO) | 95.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Decernotinib
CAS:944842-54-0
Decernotinib (VRT-831509)(VX-509; VRT-831509) is a potent and selective Janus kinase 3 (JAK3) inhibitor with Ki …
Formula:
C18H19F3N6O
Purity:
100% - 99.45%
Color and Shape:
Solid
Molecular weight:
392.38
Ref: TM-T2636
| 1mg | 52.00 € | ||
| 2mg | 68.00 € | ||
| 5mg | 93.00 € | ||
| 10mg | 130.00 € | ||
| 25mg | 257.00 € | ||
| 50mg | 456.00 € | ||
| 100mg | 639.00 € | ||
| 500mg | 1,327.00 € | ||
| 1mL*10mM (DMSO) | 89.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
G5-7
CAS:939681-36-4
G5-7 is an oral JAK2 inhibitor targeting EGFR/STAT3 phosphorylation with potential for glioma research.
Formula:
C22H19F2NO3
Purity:
97.30%
Color and Shape:
Solid
Molecular weight:
383.39
Ref: TM-T8742
| 1mg | 49.00 € | ||
| 5mg | 93.00 € | ||
| 10mg | 141.00 € | ||
| 25mg | 250.00 € | ||
| 50mg | 360.00 € | ||
| 100mg | 505.00 € | ||
| 200mg | 685.00 € | ||
| 1mL*10mM (DMSO) | 102.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
AG-494
CAS:133550-35-3
AG-494 (Tyrphostin B48) is an inhibitor of epidermal growth factor receptor kinase.
Formula:
C16H12N2O3
Purity:
98.9%
Color and Shape:
Solid
Molecular weight:
280.28
Ref: TM-T4205
| 5mg | 41.00 € | ||
| 10mg | 66.00 € | ||
| 25mg | 120.00 € | ||
| 50mg | 184.00 € | ||
| 100mg | 323.00 € | ||
| 1mL*10mM (DMSO) | 47.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
(E/Z)-Zotiraciclib
CAS:937270-47-8
(E/Z)-Zotiraciclib ((E/Z)-TG02) inhibits CDK2, JAK2, and FLT3 effectively with IC50s of 13, 73, and 56 …
Formula:
C23H24N4O
Purity:
97% - 99.12%
Color and Shape:
Solid
Molecular weight:
372.46
Ref: TM-T21503
| 1mg | 45.00 € | ||
| 2mg | 58.00 € | ||
| 5mg | 96.00 € | ||
| 10mg | 118.00 € | ||
| 25mg | 207.00 € | ||
| 50mg | 343.00 € | ||
| 100mg | 495.00 € | ||
| 1mL*10mM (DMSO) | 95.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
