Tyrosine Kinase/Adaptors
Tyrosine kinase and adaptor inhibitors are compounds that target tyrosine kinases and their associated adaptor proteins, which play pivotal roles in cell signaling, growth, and differentiation. These inhibitors are essential tools in cancer research, as many tyrosine kinases are involved in the signaling pathways that drive tumor growth and metastasis. By inhibiting tyrosine kinases, these compounds can block critical signaling cascades, offering potential therapeutic strategies for various cancers and other diseases involving abnormal cell signaling. At CymitQuimica, we provide a comprehensive range of high-quality tyrosine kinase and adaptor inhibitors to support your research in oncology, molecular biology, and targeted therapy development.
Subcategories of "Tyrosine Kinase/Adaptors"
- ALK(137 products)
- CSF-1R(42 products)
- EGFR(581 products)
- Ephrin Receptor(25 products)
- FLT(86 products)
- Fibroblast Growth Factor Receptor (FGFR)(180 products)
- HER(6 products)
- Hck(3 products)
- IGF-1R(102 products)
- PDGFR(129 products)
- PYK2(7 products)
- Src(82 products)
- TAM Receptor(34 products)
- Tie-2(20 products)
- Trk receptor(56 products)
- Tyrosine Kinases(8 products)
- VEGFR(242 products)
- c-Fms(108 products)
- c-Kit(117 products)
- c-Met/HGFR(144 products)
- c-RET(61 products)
Show 13 more subcategories
Found 1043 products of "Tyrosine Kinase/Adaptors"
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Anti-Mouse CD117 Antibody
Anti-Mouse CD117 Antibody, a rat-derived IgG2b isotype, acts as an inhibitor specific to the mouse CD117 antigen.Purity:98%Color and Shape:Odour LiquidDavutamig
CAS:Davutamig (REGN-5093) is a humanized IgG4-kappa, anti-MET monoclonal antibody that binds to two distinct, nonoverlapping epitopes on the MET receptor.Purity:98%Color and Shape:LiquidFasinumab
CAS:Fasinumab (anti-NGF mAb) is in Phase III trials for acute sciatica & knee OA. It significantly improves pain & function vs. placebo.Purity:95%Color and Shape:LiquidMolecular weight:144.89 kDaFigitumumab
CAS:Figitumumab is a potent anti-IGF1R mAb (IC50=1.8 nM) showing promise in advanced lung squamous cell carcinoma.Purity:95%Color and Shape:LiquidMolecular weight:~150 kDaEGFR T790M/L858R-IN-8
CAS:EGFRT790M/L858R-IN-8 (compound 9) is a potent inhibitor of EGFR, specifically targeting the EGFRT790M/L858R mutations with an IC50 of 56.8 μM. This compound does not show significant antiproliferative effects on cancer cell lines A549, A431, and NHI-H1975.Formula:C16H11BrN2O3Color and Shape:SolidMolecular weight:359.17Anti-IGFBP2 Antibody (M14)
Anti-IGFBP2 Antibody (M14) is a human monoclonal antibody inhibitor that binds with high affinity to IGFBP2 and prevents its interaction with IGF1. Additionally, Anti-IGFBP2 Antibody (M14) can inhibit the recruitment of human endothelial cells, thereby obstructing tumor progression in human metastatic cancers.Color and Shape:Odour LiquidFidasimtamab
CAS:Fidasimtamab, a recombinant human IgG1 bispecific antibody, targets both HER2 and PD-1, bridging T cells and tumor cells to modulate immune responses.Purity:95% - 98.0% (SDS-PAGE); 98.3% (SEC-HPLC)Color and Shape:LiquidMolecular weight:144.72 kDaTyrphostin AG 494
CAS:Formula:C16H12N2O3Purity:>98.0%(HPLC)(N)Color and Shape:Light yellow to Amber to Dark green powder to crystalMolecular weight:280.28ZM323881 hydrochloride
CAS:ZM323881 hydrochloride (ZM 323881 HCl) is a potent and selective VEGFR2 inhibitor.Formula:C22H19ClFN3O2Purity:99.43%Color and Shape:SolidMolecular weight:411.86Ref: TM-T1991
1mg34.00€5mg66.00€10mg96.00€25mg225.00€50mg369.00€100mg550.00€200mg780.00€1mL*10mM (DMSO)69.00€IGF-1R modulator 1
CAS:IGF-1Rmodulator 1 (Example 5) is an IGF-1R modulator featuring an EC50 of 0.29 μM (FGFR1), 0.25 μM (IGF1R), 0.34 μM (TrkA), and 0.39 μM (TrkB). This compound is useful in research on diseases characterized by impaired signaling of neurotrophic and/or other trophic factors, such as Alzheimer's disease.Formula:C22H17N3O4Color and Shape:SolidMolecular weight:387.39CSF1R-IN-19
CAS:CSF1R-IN-19 is a robust inhibitor of CSF1R that influences the exchange of inflammatory factors between TAMs and glioma cells. It holds potential for cancer research [1].Formula:C20H27N7OColor and Shape:SolidMolecular weight:381.47lavendustin A
CAS:lavendustin A (RG-14355) is a potent, cell-permeable inhibitor of epidermal growth factor receptor (EGFR) tyrosine kinase.Formula:C21H19NO6Purity:98%Color and Shape:Off-White SolidMolecular weight:381.38Icotinib
CAS:Icotinib (Conmana) is an orally available quinazoline-based inhibitor of epidermal growth factor receptor (EGFR), with potential antineoplastic activity.Formula:C22H21N3O4Purity:99.76% - 99.94%Color and Shape:SolidMolecular weight:391.42S961
CAS:S961: High-affinity IR antagonist; IC50: HIR-A 0.048 nM, HIR-B 0.027 nM, HIGF-IR 630 nM.Formula:C211H297N55O71S2Purity:98%Color and Shape:SolidMolecular weight:4804.138-MA-cAMP
CAS:8-MA-cAMP (8-Methylamino-cAMP) is a cyclic adenosine monophosphate analog that acts as a site-selective PKA agonist, exhibiting similar affinity for the B site of both Type I and Type II protein kinase A. When used in conjunction with analogs that preferentially target site A, such as 8-piperidinyl cAMP, 8-MA-cAMP facilitates selective stimulation of Type I enzymes.Formula:C11H15N6O6PColor and Shape:SolidMolecular weight:358.258-Chloro-cAMP sodium
CAS:8-Chloro-cAMP sodium is a cAMP analog that induces growth arrest and modulates cAMP-dependent PKA activity. This compound also exhibits anticancer activity.Formula:C10H10ClN5NaO6PColor and Shape:SolidMolecular weight:385.63Icotinib Hydrochloride
CAS:Icotinib Hydrochloride, an oral EGFR inhibitor (BPI-2009H), may halt cancer growth by blocking EGFR signaling.Formula:C22H22ClN3O4Purity:99.89%Color and Shape:SolidMolecular weight:427.88TAK-285
CAS:TAK-285 is a novel dual HER2 and EGFR(HER1) inhibitor, >10-fold selectivity for HER1/2 than HER4, less potent to MEK1/5, c-Met, Aurora B, Lck, CSK etc.Formula:C26H25ClF3N5O3Purity:99.73%Color and Shape:SolidMolecular weight:547.96Ref: TM-T6039
1mg38.00€5mg80.00€10mg120.00€25mg216.00€50mg354.00€100mg512.00€200mg727.00€1mL*10mM (DMSO)96.00€AMG-458
CAS:AMG-458 is a potent c-Met inhibitor with Ki of 1.2 nM, ~350-fold selectivity for c-Met than VEGFR2 in cells.Formula:C30H29N5O5Purity:99.91% - 99.98%Color and Shape:SolidMolecular weight:539.58BMS-754807
CAS:BMS-754807 is an oral IGF-1R/InsR inhibitor with potential anti-cancer properties.Formula:C23H24FN9OPurity:99.69% - 99.94%Color and Shape:SolidMolecular weight:461.49Ref: TM-T2349
1mg50.00€2mg66.00€5mg90.00€10mg158.00€25mg310.00€50mg509.00€100mg732.00€1mL*10mM (DMSO)110.00€
