Interested?
Enter your email address to receive promotions, discounts and to be the first to hear about hot sales and other CymitQuimica events!
ALK
LDN193189
CAS:1062368-24-4
LDN193189 (DM 3189) is a selective BMP signaling inhibitor, inhibiting the transcriptional activity of ALK2 …
Formula:
C25H22N6
Purity:
99.11%
Color and Shape:
solid
Molecular weight:
406.48
Estimated delivery in United States, on Tuesday 1 Feb 2022
6-Demethoxytangeretin
CAS:6601-66-7
6-Demethoxytangeretin is a citrus flavonoid isolated from Citrus depressa.
Formula:
C19H18O6
Purity:
99.89%
Color and Shape:
solid
Molecular weight:
342.3
Estimated delivery in United States, on Tuesday 1 Feb 2022
ALK2-IN-2
CAS:2254409-25-9
ALK2-IN-2 is a potent and selective inhibitor of ALK2 (IC50: 9 nM), and over 700-fold …
Formula:
C28H27N5O2S
Purity:
98.00%
Color and Shape:
Solid
Molecular weight:
497.61
Estimated delivery in United States, on Tuesday 1 Feb 2022
ALK-IN-5
CAS:2351929-66-1
ALK-IN-5 is a potent, selective, and brain-penetrant inhibitor of anaplastic lymphoma kinase (ALK, IC50: 2.9 …
Formula:
C24H25FN6O3
Purity:
98.00%
Color and Shape:
Solid
Molecular weight:
464.49
Estimated delivery in United States, on Tuesday 1 Feb 2022
IN-1130
CAS:868612-83-3
IN-1130 is a highly selective inhibitor of transforming growth factor- type I receptor kinase (ALK5) …
Formula:
C25H20N6O
Purity:
98.00%
Color and Shape:
solid
Molecular weight:
420.47
Estimated delivery in United States, on Tuesday 1 Feb 2022
Ensartinib
CAS:1365267-27-1
Ensartinib (X-396) is an orally available small molecule inhibitor of the receptor tyrosine kinase anaplastic …
Formula:
C25H25Cl2FN5O3
Purity:
98.29%
Color and Shape:
solid
Molecular weight:
547.41
Estimated delivery in United States, on Tuesday 1 Feb 2022
LDN212854
CAS:1432597-26-6
LDN-212854, a novel BMP inhibitor, exhibits greater selectivity for BMP versus the TGF- type I …
Formula:
C25H22N6
Purity:
99.38%
Color and Shape:
solid
Molecular weight:
406.48
Estimated delivery in United States, on Tuesday 1 Feb 2022
HG-14-10-04
CAS:1356962-34-9
HG-14-10-04 is a potent and specific ALK inhibitor.
Formula:
C29H34ClN7O
Purity:
98.36%
Color and Shape:
solid
Molecular weight:
532.08
Estimated delivery in United States, on Tuesday 1 Feb 2022
Belizatinib
CAS:1357920-84-3
Belizatinib is an effective, oral and dual inhibitor of ALK (IC50: 0.7 nM, wild-type recombinant …
Formula:
C33H44FN5O3
Purity:
99.33%
Color and Shape:
Solid
Molecular weight:
577.75
Estimated delivery in United States, on Tuesday 1 Feb 2022
SB 431542
CAS:301836-41-9
SB-431542 is a potent and selective inhibitor of ALK5 (IC50: 94 nM) and is also …
Formula:
C22H16N4O3
Purity:
98.00%
Color and Shape:
solid
Molecular weight:
384.39
Estimated delivery in United States, on Tuesday 1 Feb 2022
LDK378
CAS:1032900-25-6
Ceritinib (LDK378) is a specific ALK inhibitor (IC50: 0.2 nM).
Formula:
C28H36ClN5O3S
Purity:
100.00%
Color and Shape:
solid
Molecular weight:
558.14
Estimated delivery in United States, on Tuesday 1 Feb 2022
Lorlatinib
CAS:1454846-35-5
PF-06463922 is an orally available, ATP-competitive inhibitor of the receptor tyrosine kinases, anaplastic lymphoma kinase …
Formula:
C21H19FN6O2
Purity:
99.00%
Color and Shape:
solid
Molecular weight:
406.41
Estimated delivery in United States, on Tuesday 1 Feb 2022
Entrectinib
CAS:1108743-60-7
Entrectinib is an inhibitor of TrkA (IC50: 1.7 nM), TrkB (IC50: 0.1 nM), and TrkC …
Formula:
C31H34F2N6O2
Purity:
99.49%
Color and Shape:
solid
Molecular weight:
560.64
Estimated delivery in United States, on Tuesday 1 Feb 2022
LDN214117
CAS:1627503-67-6
LDN-214117 is a potent and selective ALK2 inhibitor.
Formula:
C25H29N3O3
Purity:
98.00%
Color and Shape:
Solid
Molecular weight:
419.52
Estimated delivery in United States, on Tuesday 1 Feb 2022
Vactosertib Hydrochloride
CAS:1352610-25-3
Vactosertib Hydrochloride is an orally active and ATP-competitive ALK5 inhibitor (IC50: 12.9 nM). It has …
Formula:
C22H19ClFN7
Purity:
98.00%
Color and Shape:
Solid
Molecular weight:
435.88
Estimated delivery in United States, on Tuesday 1 Feb 2022
Crizotinib
CAS:877399-52-5
Crizotinib is an ATP-competitive small-molecule tyrosine kinases inhibitor of c-MET (IC50: 8 nM) and ALK …
Formula:
C21H22Cl2FN5O
Purity:
99.00%
Color and Shape:
solid
Molecular weight:
450.34
Estimated delivery in United States, on Tuesday 1 Feb 2022
ALK5 Inhibitor IV
CAS:909910-43-6
A 83-01 is a selective inhibitor of TGF- type I receptor ALK5 kinase, type I …
Formula:
C25H19N5S
Purity:
97.00%
Color and Shape:
solid
Molecular weight:
421.52
Estimated delivery in United States, on Tuesday 1 Feb 2022
SB505124
CAS:694433-59-5
SB505124 is a selective inhibitor of TGFR for ALK4, ALK5.
Formula:
C20H21N3O2
Purity:
99.00%
Color and Shape:
solid
Molecular weight:
335.4
Estimated delivery in United States, on Tuesday 1 Feb 2022
CEP28122
CAS:1022958-60-6
CEP-28122 is a highly potent and selective orally active ALK inhibitor.
Formula:
C28H35ClN6O3
Purity:
100.00%
Color and Shape:
solid
Molecular weight:
539.07
Estimated delivery in United States, on Tuesday 1 Feb 2022
SM 16
CAS:614749-78-9
SM 16 is a ALK5/ALK4 kinase inhibitor (Ki: 10/1.5 nM).
Formula:
C25H26N4O3
Purity:
99.81%
Color and Shape:
Solid
Molecular weight:
430.5
Estimated delivery in United States, on Tuesday 1 Feb 2022
LDK378 dihydrochloride
CAS:1380575-43-8
Ceritinib dihydrochloride is a selective, orally bioavailable and ATP-competitive inhibitor of ALK tyrosine kinase(IC50 of …
Formula:
C28H38Cl3N5O3S
Purity:
99.99%
Color and Shape:
solid
Molecular weight:
631.06
Estimated delivery in United States, on Tuesday 1 Feb 2022
Alectinib hydrochloride
CAS:1256589-74-8
Alectinib hydrochloride is a selective, and orally available inhibitor of ALK( IC50 : 1.9 nM)
Formula:
C30H35ClN4O2
Purity:
99.96%
Color and Shape:
solid
Molecular weight:
519.08
Estimated delivery in United States, on Tuesday 1 Feb 2022
TPX0005
CAS:1802220-02-5
TPX-0005 is a potent ALK/ROS1/TRK inhibitor, with IC50 of 1.01 nM, 5.3 nM, 1.08 nM …
Formula:
C18H18FN5O2
Purity:
100.00%
Color and Shape:
Solid
Molecular weight:
355.37
Estimated delivery in United States, on Tuesday 1 Feb 2022
MS4077
CAS:2230077-10-6
MS4077 is an degrader of anaplastic lymphoma kinase (ALK) PROTAC(Kd of 37 nM for binding …
Formula:
C55H72ClN9O13S
Purity:
98.00%
Color and Shape:
Solid
Molecular weight:
1134.73
Estimated delivery in United States, on Tuesday 1 Feb 2022
Crizotinib hydrochloride
CAS:1415560-69-8
Crizotinib hydrochloride is a novel inhibitor of anaplastic lymphoma kinase and c-Met(IC50s of 20 and …
Formula:
C21H23Cl3FN5O
Purity:
99.67%
Color and Shape:
solid
Molecular weight:
486.8
Estimated delivery in United States, on Tuesday 1 Feb 2022
AZ12601011
AZ12601011 is an orally active, selective TGFBR1 kinase inhibitor (IC50: 18 nM; Kd: 2.9 nM) …
Formula:
C19H15N5
Purity:
98.00%
Color and Shape:
solid
Molecular weight:
313.36
Estimated delivery in United States, on Tuesday 1 Feb 2022
A 83-01 sodium salt
A 83-01 sodium salt is a potent inhibitor of ALK5 kinase, type I activin/nodal receptor …
Formula:
C25H19N5NaS
Purity:
98.00%
Color and Shape:
solid
Molecular weight:
444.51
Estimated delivery in United States, on Tuesday 1 Feb 2022
(-)-Cevimeline hydrochloride hemihydrate
(-)-Cevimeline hydrochloride hemihydrate is an agonist of muscarinic receptor.
Formula:
C10H17NOSHClH2O
Purity:
98.00%
Color and Shape:
solid
Molecular weight:
244.78
Estimated delivery in United States, on Tuesday 1 Feb 2022
R-268712
CAS:879487-87-3
R-268712 is a specific activin receptor-like kinase 5 (ALK5) inhibitor(IC50 of 2.5 nM). It is …
Formula:
C20H18FN5O
Purity:
99.77%
Color and Shape:
Solid
Molecular weight:
363.39
Estimated delivery in United States, on Tuesday 1 Feb 2022
Blu-782
CAS:2141955-96-4
Blu-782 is a activin receptor-like kinase-2 (ALK2) inhibitor ( IC50 of <10 nM)
Formula:
C31H42N6O4
Purity:
98.59%
Color and Shape:
Solid
Molecular weight:
562.7
Estimated delivery in United States, on Tuesday 1 Feb 2022
Vactosertib
CAS:1352608-82-2
Vactosertib is an orally bioavailable inhibitor of the serine/threonine kinase, transforming growth factor (TGF)-beta receptor …
Formula:
C22H18FN7
Purity:
99.43%
Color and Shape:
solid
Molecular weight:
399.42
Estimated delivery in United States, on Tuesday 1 Feb 2022
GW 788388
CAS:452342-67-5
GW788388 is a potent and selective inhibitor of ALK5, also inhibits TGF-(beta) type II receptor …
Formula:
C25H23N5O2
Purity:
98.00%
Color and Shape:
solid
Molecular weight:
425.48
Estimated delivery in United States, on Tuesday 1 Feb 2022
CEP-28122 mesylate salt (1022958-60-6 free base)
CEP-28122 mesylate salt is a highly selective orally active ALK inhibitor (IC50: 1.9 nM in …
Formula:
C29H39ClN6O6S
Purity:
99.19%
Molecular weight:
635.17
Estimated delivery in United States, on Tuesday 1 Feb 2022
TGFBR1-IN-1
CAS:2170830-26-7
TGFBR1-IN-1 is an inhibitor of ALK5 (IC50 of 10-100 nM).
Formula:
C23H17N5O2S
Purity:
98.00%
Color and Shape:
Solid
Molecular weight:
427.48
Estimated delivery in United States, on Tuesday 1 Feb 2022
A77-01
CAS:607737-87-1
A 77-01 is a potent inhibitor of TGF-(beta) type I receptor superfamily activin-like kinase ALK5 …
Formula:
C18H14N4
Purity:
99.56%
Color and Shape:
solid
Molecular weight:
286.33
Estimated delivery in United States, on Tuesday 1 Feb 2022
Ensartinib dihydrochloride
CAS:2137030-98-7
Ensartinib dihydrochloride is a potent new-generation ALK inhibitor with high activity against CNS metastases and …
Formula:
C26H29Cl4FN6O3
Purity:
99.29%
Color and Shape:
Solid
Molecular weight:
634.36
Estimated delivery in United States, on Tuesday 1 Feb 2022
ASP 3026
CAS:1097917-15-1
ASP3026 has been used in trials studying the treatment of Solid Tumor, B-Cell Lymphoma, Advanced …
Formula:
C29H40N8O3S
Purity:
98.00%
Color and Shape:
solid
Molecular weight:
580.74
Estimated delivery in United States, on Tuesday 1 Feb 2022
Wy 49051
CAS:113418-56-7
Wy 49051 is an orally active antagonist of H1 receptor(IC50 of 44 nM).
Formula:
C28H33N5O3
Purity:
98.00%
Color and Shape:
Solid
Molecular weight:
487.59
Estimated delivery in United States, on Tuesday 1 Feb 2022
GSK1838705A
CAS:1116235-97-2
GSK1838705A is an effective IGF-1R inhibitor (IC50: 2.0 nM), modestly potent to IR (IC50: 1.6 …
Formula:
C27H29FN8O3
Purity:
98.89%
Color and Shape:
solid
Molecular weight:
532.57
Estimated delivery in United States, on Tuesday 1 Feb 2022
D 4476
CAS:301836-43-1
D4476 is an effective, selective, and cell-permeant CK1 (casein kinase 1) inhibitor( IC50=300 nM in …
Formula:
C23H18N4O3
Purity:
99.96%
Color and Shape:
solid
Molecular weight:
398.41
Estimated delivery in United States, on Tuesday 1 Feb 2022
KRCA0008
CAS:1472795-20-2
KRCA-0008 is an effective and specific ALK/Ack1 inhibitor (IC50: 12/4 nM); displays drug-like properties without …
Formula:
C30H37ClN8O4
Purity:
96.19%
Color and Shape:
Solid
Molecular weight:
609.12
Estimated delivery in United States, on Tuesday 1 Feb 2022
Alectinib
CAS:1256580-46-7
CH5424802 is an orally available inhibitor of the receptor tyrosine kinase anaplastic lymphoma kinase (ALK) …
Formula:
C30H34N4O2
Purity:
99.27%
Color and Shape:
solid
Molecular weight:
482.62
Estimated delivery in United States, on Tuesday 1 Feb 2022
AP26113
CAS:1197958-12-5
AP26113 is a potent ALK inhibitor with IC50 of 0.62 nM in a cell-free assay, …
Formula:
C26H34ClN6O2P
Purity:
97.66%
Color and Shape:
solid
Molecular weight:
529.01
Estimated delivery in United States, on Tuesday 1 Feb 2022
ML347
CAS:1062368-49-3
ML347(DN193719) is a highly specific ALK1/2 inhibitor ( IC50: 46/32 nM), and the selectivity for …
Formula:
C22H16N4O
Purity:
98.00%
Color and Shape:
solid
Molecular weight:
352.39
Estimated delivery in United States, on Tuesday 1 Feb 2022
CEP37440
CAS:1391712-60-9
CEP-37440 is an effective and specific Dual FAK/ALK inhibitor with IC50s of 120 nM(ALK cellular …
Formula:
C30H38ClN7O3
Purity:
99.92%
Color and Shape:
solid
Molecular weight:
580.12
Estimated delivery in United States, on Tuesday 1 Feb 2022
LDN-193189 HCl
CAS:1062368-62-0
LDN193189 hydrochloride is a selective BMP type I receptor kinases inhibitor.
Formula:
C25H22N6·HCl
Purity:
99.49%
Color and Shape:
solid
Molecular weight:
442.94
Estimated delivery in United States, on Tuesday 1 Feb 2022
DMH1
CAS:1206711-16-1
DMH-1 is a potent and selective BMP inhibitor.
Formula:
C24H20N4O
Purity:
98.00%
Color and Shape:
solid
Molecular weight:
380.44
Estimated delivery in United States, on Tuesday 1 Feb 2022
AZD3463
CAS:1356962-20-3
AZD3463, an orally bioavailable ALK inhibitor (Ki: 0.75 nM), can inhibit IGF1R with equivalent potency.
Formula:
C24H25ClN6O
Molecular weight:
448.95
Estimated delivery in United States, on Tuesday 1 Feb 2022
RepSox
CAS:446859-33-2
RepSox is a potent and selective of the TGFR-1/ALK5 inhibitor.
Formula:
C17H13N5
Purity:
98.57%
Color and Shape:
solid
Molecular weight:
287.32
Estimated delivery in United States, on Tuesday 1 Feb 2022
TAE684
CAS:761439-42-3
NVP-TAE 684 is a excellently effective and specific ALK inhibitor(IC50=3 nM).
Formula:
C30H40ClN7O3S
Purity:
98.00%
Color and Shape:
solid
Molecular weight:
614.2
Estimated delivery in United States, on Tuesday 1 Feb 2022
ALK inhibitor 2
CAS:761438-38-4
ALK inhibitor 2 is a new-type and selective inhibitor for the ALK kinase.
Formula:
C23H28ClN7O3S
Purity:
99.77%
Color and Shape:
solid
Molecular weight:
518.03
Estimated delivery in United States, on Tuesday 1 Feb 2022
K 02288
CAS:1431985-92-0
K02288 is a novel small molecule inhibitor of ALK1/2/3/6.
Formula:
C20H20N2O4
Purity:
99.81%
Color and Shape:
solid
Molecular weight:
352.38
Estimated delivery in United States, on Tuesday 1 Feb 2022
CH5424802 analog
CAS:1256577-71-5
CH5424802 analog is a selective ALK inhibitor capable of blocking the resistant gatekeeper mutant.
Formula:
C28H30N4O2
Molecular weight:
454.56
Estimated delivery in United States, on Tuesday 1 Feb 2022
N-Methylisatoic anhydride
CAS:10328-92-4
N-Methylisatoic anhydride is a 2'-OH selective acylation agent of RNAs. It is also widely used …
Formula:
C9H7NO3
Purity:
95.27%
Color and Shape:
Brownish Chunks
Molecular weight:
177.16
Estimated delivery in United States, on Tuesday 1 Feb 2022
