ALK
ALK inhibitors are compounds that specifically target and inhibit Anaplastic Lymphoma Kinase (ALK), a receptor tyrosine kinase involved in the development and progression of certain cancers, including non-small cell lung cancer and neuroblastoma. By inhibiting ALK, these compounds block signaling pathways that promote tumor cell growth and survival. At CymitQuimica, we offer ALK inhibitors to support your research in oncology, targeted cancer therapies, and signal transduction.
Found 154 products for "ALK".
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Crizotinib acetate
CAS:Crizotinib is an oral c-met/HGFR tyrosine kinase inhibitor with potential cancer-fighting properties.Formula:C23H26Cl2FN5O3Color and Shape:SolidMolecular weight:510.39Blu-782
CAS:Blu-782 (ALK2-IN-1) is a activin receptor-like kinase-2 (ALK2) inhibitor ( IC50 of <10 nM)Formula:C31H42N6O4Purity:99.51%Color and Shape:SolidMolecular weight:562.7DMH-1
CAS:DMH-1 is a BMP inhibitor that inhibits ALK1, ALK2, ALK3 and ALK6. DMH-1 promotes pluripotent stem cell differentiation. Cost-effective and quality-assured.Formula:C24H20N4OPurity:98% - 99.92%Color and Shape:SolidMolecular weight:380.44ALK kinase inhibitor-1
CAS:SAR348830 is an ALK inhibitor, targeting anaplastic lymphoma kinase.Formula:C28H32FN5O3SPurity:99.84%Color and Shape:SolidMolecular weight:537.65Vactosertib Hydrochloride
CAS:Vactosertib Hydrochloride (EW-7197 Hydrochloride) is an ALK5 inhibitor, a TGF-β receptor I inhibitor with antimetastatic and anticancer effects.Formula:C22H19ClFN7Purity:98.03%Color and Shape:White SolidMolecular weight:435.89A 83-01 sodium salt
CAS:A 83-01 sodium salt inhibits ALK5, ALK4, and ALK7 kinases with IC50s: 12, 45, 7.5 nM.Formula:C25H19N5NaSColor and Shape:SolidMolecular weight:444.51LDN-212854
CAS:LDN-212854 (BMP Inhibitor III), a novel BMP inhibitor, exhibits greater selectivity for BMP versus the TGF-β type I receptors.Formula:C25H22N6Purity:98% - 98.71%Color and Shape:White SolidMolecular weight:406.48Ref: TM-T1900
1mg47.00€2mg62.00€5mg92.00€1mL*10mM (DMSO)102.00€10mg172.00€25mg294.00€50mg439.00€100mg660.00€200mg945.00€K02288
CAS:K 02288 is a novel small molecule inhibitor of ALK1/2/3/6.Formula:C20H20N2O4Purity:98% - 99.83%Color and Shape:SolidMolecular weight:352.38CH5424802 analog
CAS:CH5424802 analog is a selective ALK inhibitor capable of blocking the resistant gatekeeper mutant.Formula:C28H30N4O2Purity:98.96%Color and Shape:White SolidMolecular weight:454.56Ref: TM-T9224
1mg124.00€5mg271.00€1mL*10mM (DMSO)324.00€10mg408.00€25mg672.00€50mg945.00€100mg1,279.00€ALK5-IN-10
CAS:Compound 12d is a potent ALK5 inhibitor with an IC50 of 7nM.Formula:C22H18BrN7Purity:99.93%Color and Shape:SolidMolecular weight:460.33LDN-193189 HCl
CAS:LDN-193189 HCl (LDN193189 Hydrochloride) is a selective BMP type I receptor kinases inhibitor.Formula:C25H22N6·HClPurity:99.49% - 99.53%Color and Shape:SolidMolecular weight:442.94Ref: TM-T6158
1mg34.00€2mg46.00€5mg66.00€1mL*10mM (DMSO)73.00€10mg88.00€25mg147.00€50mg215.00€100mg358.00€200mg537.00€Repotrectinib
CAS:Repotrectinib (TPX-0005) is a potent ALK/ROS1/TRK inhibitor, with IC50 of 1.01/5.3/1.08/1.26 nM for WT ALK, SRC, ALK L1196M and ALK G1202R, respectively.Formula:C18H18FN5O2Purity:99.85% - >99.99%Color and Shape:SolidMolecular weight:355.37Ref: TM-T4071
1mg44.00€1mL*10mM (DMSO)92.00€5mg93.00€10mg133.00€25mg260.00€50mg394.00€100mg592.00€200mg827.00€SB-431542
CAS:SB-431542 is an inhibitor of ALK5/TGF-β type I Receptor (IC50=94 nM) and is selective.Formula:C22H16N4O3Purity:99.03% - >99.99%Color and Shape:Yellow SolidMolecular weight:384.39NVP-TAE 684
CAS:NVP-TAE 684 (TAE684) is a excellently effective and specific ALK inhibitor(IC50=3 nM).Formula:C30H40ClN7O3SPurity:98% - 99.82%Color and Shape:White SolidMolecular weight:614.2SM 16
CAS:SM 16 is a ALK5/ALK4 kinase inhibitor (Ki: 10/1.5 nM).Formula:C25H26N4O3Purity:99.72%Color and Shape:SolidMolecular weight:430.5Alectinib
CAS:Alectinib (RG-7853) is an ALK inhibitor that is selective, orally active, and ATP-competitive. Alectinib has antitumor activity. Cost-effective and quality-assured.Formula:C30H34N4O2Purity:98% - 99.94%Color and Shape:White SolidMolecular weight:482.62Ref: TM-T1936
2mg44.00€5mg65.00€1mL*10mM (DMSO)70.00€10mg82.00€50mg100.00€100mg159.00€200mg245.00€500mg414.00€GSK1838705A
CAS:GSK1838705A: IGF-1R inhibitor (IC50=2.0nM), IR (1.6nM), ALK (0.5nM), minimal other kinase impact.Formula:C27H29FN8O3Purity:98.89% - >99.99%Color and Shape:Yellow SolidMolecular weight:532.57CAY10594
CAS:CAY10594, a PLD2 inhibitor, mitigates acetaminophen liver damage via the p-GSK-3β/JNK pathway.Formula:C26H28N4O2Purity:97.76%Color and Shape:White SolidMolecular weight:428.53LDN-214117
CAS:LDN-214117 is a potent and selective ALK2 inhibitor.Formula:C25H29N3O3Purity:98% - 99.83%Color and Shape:SolidMolecular weight:419.52LDN193189
CAS:LDN193189 blocks BMP signaling by inhibiting ALK2/3; IC50: ALK1/2/3/6 = 0.8/0.8/5.3/16.7 nM.Formula:C25H22N6Purity:98% - 99.86%Color and Shape:SolidMolecular weight:406.48
