c-Fms
c-Fms inhibitors target the Colony Stimulating Factor-1 Receptor (c-Fms), a tyrosine kinase involved in the regulation of macrophages and other immune cells. c-Fms signaling plays a role in the proliferation, differentiation, and survival of these cells. Dysregulation of c-Fms is associated with diseases such as cancer, inflammatory conditions, and osteoporosis. At CymitQuimica, we offer c-Fms inhibitors to support your research in immunology, oncology, and inflammatory diseases.
Found 110 products of "c-Fms"
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Lacnotuzumab
CAS:Lacnotuzumab (MCS110) is a humanized monoclonal antibody targeting CSF-1, which can be used in research on retinal diseases.Purity:>95%Color and Shape:LiquidMolecular weight:144.8 kDaMavrilimumab
CAS:Mavrilimumab (CAM 3001), a monoclonal antibody, blocks GM-CSF signaling, potentially reducing inflammation in rheumatoid arthritis.Purity:> 95% - > 95%Color and Shape:LiquidMolecular weight:143.2 kDaEdicotinib
CAS:Edicotinib (JNJ-527) is a blood-brain permeable, selective CSF-1R inhibitor, with lesser inhibitory effects on KIT and FLT3.Cost-effective and quality-assured.
Formula:C27H35N5O2Purity:98.58% - 99.72%Color and Shape:SolidMolecular weight:461.6CSF1R-IN-2
CAS:CSF1R-IN-2 is an oral-active SRC, MET and c-FMS inhibitor (IC50s: 0.12 nM, 0.14 nM and 0.76 nM for SRC, MET and c-FMS respectively).Formula:C20H20FN7O2Purity:99.29%Color and Shape:SolidMolecular weight:409.42Emactuzumab
CAS:Emactuzumab(RG 7155) is a monoclonal antibody against colony-stimulating factor-1 receptor targeting tumor-associated macrophages (TAMs) Emactuzumab has
Purity:SDS-PAGE:98.3%;SEC-HPLC:97.3%Color and Shape:LiquidMolecular weight:144.4 kDaCSF1R-IN-1
CAS:CSF1R-IN-1 is a CSF1R inhibitor with IC50 of 0.5 nM.Formula:C25H20F3N5O2Purity:97.02% - 98.56%Color and Shape:SolidMolecular weight:479.45Ref: TM-T10894
1mg88.00€5mg200.00€1mL*10mM (DMSO)219.00€10mg309.00€25mg522.00€50mg747.00€100mg1,035.00€200mg1,378.00€Otilimab
CAS:Otilimab, a humanized monoclonal antibody, blocks GM-CSF to reduce inflammation and may treat severe COVID-19 pneumonia.
Purity:> 95%Color and Shape:LiquidMolecular weight:142.22 kDaGENZ-882706(Raceme)
CAS:GENZ-882706(Raceme) is the racemate of GENZ-882706.Formula:C26H25N5O3Purity:98%Color and Shape:SolidMolecular weight:455.51PLX647 dihydrochloride
CAS:PLX647 dihydrochloride: potent FMS/KIT inhibitor (IC50: 28/16 nM), highly selective, limited FLT3/KDR activity, oral use.Formula:C21H19Cl2F3N4Color and Shape:SolidMolecular weight:455.31Sotuletinib hydrochloride
CAS:Sotuletinib hydrochloride (BLZ945 HCl) is a selective, brain-penetrant CSF-1R (c-Fms) inhibitor (IC50=1 nM),for ALS and TNBC.Formula:C20H23ClN4O3SPurity:98.81%Color and Shape:SolidMolecular weight:434.94Eflapegrastim
CAS:Eflapegrastim: humanized IgG4 antibody and G-CSF that boosts neutrophils and shortens neutropenia.Color and Shape:LiquidPyrithyldione
CAS:Pyrithyldione is a sedative-hypnotic agent known to potentially induce agranulocytosis.Formula:C9H13NO2Color and Shape:SolidMolecular weight:167.21PXB17
PXB17 inhibits CSF1R activation (IC50= 1.7 nM) by blocking the PI3K/AKT/mTORC1 signaling pathway. It is effective orally, significantly suppresses the growth of colorectal cancer (CRC), enhances the efficacy of PD-1 monoclonal antibodies (PD-1mAb), and reduces the recurrence of CRC tumors.Formula:C29H35N7O4Molecular weight:545.27505PD-360324
PD-360324 is a human monoclonal antibody (mAb) that targets CSF1/M-CSF. It can be utilized in research related to skin lupus, pulmonary sarcoidosis, and rheumatoid arthritis.Color and Shape:Odour LiquidGimsilumab
CAS:Gimsilumab (MORAb-022) is an anti-c-Fms humanized monoclonal antibody for the study of inflammation and hypoxemia caused by COVID-19.Purity:99.49% (SEC-HPLC) - 99.49% (SEC-HPLC)Color and Shape:LiquidMolecular weight:145.8 kDaAdrixetinib TFA
Adrixetinib (TFA) is a protein tyrosine kinase inhibitor that possesses antineoplastic properties [1] [2] [3].Color and Shape:Odour SolidcFMS Receptor Inhibitor IV
CAS:cFMS Receptor Inhibitor IV is an inhibitor of c-Fms tyrosine kinase.
Formula:C22H26N4O2Purity:99.70%Color and Shape:SolidMolecular weight:378.47CSF1R-IN-17
CSF1R-IN-17 (compound 9) is a potent, selective antagonist of CSF1R, exhibiting an inhibition concentration half-maximum (IC50) of 0.2 nM.Formula:C20H25N5O2Purity:98%Color and Shape:SolidMolecular weight:367.44AMG-820
AMG-820 is a human antibody targeting CSF-1R, inhibiting the binding of ligands CSF1 and IL34, and preventing subsequent ligand-induced receptor activation. For AMG-820's isotype control, refer to [Human IgG2 kappa, Isotype Control].Color and Shape:Odour LiquidPlonmarlimab
CAS:Plonmarlimab(TJ003234) is an anti-GM-CSF monoclonal antibody with potential antiviral activity for the study of immune disorders and novel coronavirus infectionPurity:96.2% (SDS-PAGE); 95.4% (SEC-HPLC) - 96.2% (SDS-PAGE); 95.4% (SEC-HPLC)Color and Shape:LiquidMolecular weight:145.94 kDaM4205
CAS:M4205 is an inhibitor of c-Kit exhibiting high activity on c-Kit mutations in exons 11, 13, 17.Formula:C29H32N8OPurity:99.07%Color and Shape:SolidMolecular weight:508.62Ref: TM-T9689
1mg50.00€5mg110.00€1mL*10mM (DMSO)122.00€10mg170.00€25mg290.00€50mg414.00€100mg572.00€200mg772.00€Antifibrotic agent 1
Antifibrotic agent 1 is an orally active medication designed to treat idiopathic pulmonary fibrosis (IPF). It effectively mitigates IPF-related processes, including TGF-β-induced epithelial-mesenchymal transition (EMT) and fibroblast-to-myofibroblast transition (FMT), as well as profibrotic M2 polarization. Antifibrotic agent 1 selectively inhibits CSF-1R, PDGFR-α, and Src family kinases (SFKs), while sparing VEGFR, FGFR, and Abl to minimize off-target toxicity. In a bleomycin (BLM)-induced pulmonary fibrosis mouse model, it demonstrates strong antifibrotic activity.Formula:C27H23ClN6O2Color and Shape:SolidMolecular weight:498.1571CSF1R Protein (Met1-Glu512), Human, Recombinant (His)
CSF1R Protein (Met1-Glu512), Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.Purity:SDS-PAGE: 97.7%; SEC-HPLC: 99.7%Color and Shape:Lyophilized PowderMolecular weight:56 kDa (predicted); 85-95 kDa (reducing condition, due to glycosylation)PLX647
CAS:PLX647 is a highly selective dual FMS/KIT kinase inhibitor (IC50: 28/16 nM).Formula:C21H17F3N4Purity:99.38%Color and Shape:SolidMolecular weight:382.38Ref: TM-T1925
2mg39.00€5mg57.00€1mL*10mM (DMSO)60.00€10mg86.00€25mg127.00€50mg178.00€100mg264.00€200mg389.00€Anti-CSF1R Antibody (4Y587)
Anti-CSF1R Antibody (4Y587) is a Mouse antibody targeting CSF1R. Anti-CSF1R Antibody (4Y587) can be used in FCM.Color and Shape:Odour LiquidAnti-CSF1R Antibody (5C535)
Anti-CSF1R Antibody (5C535) is a Rabbit antibody targeting CSF1R. Anti-CSF1R Antibody (5C535) can be used in ELISA.Color and Shape:Odour LiquidAnti-CSF1R Antibody (1R707)
Anti-CSF1R Antibody (1R707) is a Rabbit antibody targeting CSF1R. Anti-CSF1R Antibody (1R707) can be used in ELISA.Color and Shape:Odour LiquidAnti-CSF1R Antibody (2I506)
Anti-CSF1R Antibody (2I506) is a Mouse antibody targeting CSF1R. Anti-CSF1R Antibody (2I506) can be used in ELISA.Color and Shape:Odour LiquidAnti-CSF1R Antibody-FITC (4Y587)
Anti-CSF1R Antibody-FITC (4Y587) is a FITC-conjugated Mouse antibody targeting CSF1R. Anti-CSF1R Antibody-FITC (4Y587) can be used in FCM.Color and Shape:Odour LiquidAnti-CSF1R Antibody (7V18)
Anti-CSF1R Antibody (7V18) is a Rabbit antibody targeting CSF1R. Anti-CSF1R Antibody (7V18) can be used in ELISA.Color and Shape:Odour LiquidAnti-CSF1R Antibody (8O797)
Anti-CSF1R Antibody (8O797) is a Mouse antibody targeting CSF1R. Anti-CSF1R Antibody (8O797) can be used in ELISA.Color and Shape:Odour LiquidAnti-CSF1R Antibody (5B661)
Anti-CSF1R Antibody (5B661) is a Mouse antibody targeting CSF1R. Anti-CSF1R Antibody (5B661) can be used in ELISA,ELISA(Cap).Color and Shape:Odour LiquidCSF1R Protein, Cynomolgus, Recombinant (His)
M-CSFR/CSF1R/CD115 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag.Color and Shape:Lyophilized PowderMolecular weight:56.3 kDa (predicted). Due to glycosylation, the protein migrates to 75-105 kDa based on Tris-Bis PAGE result.CSF1R Protein, Human, Recombinant (His & Avi), Biotinylated
CSF1R Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag.Color and Shape:Lyophilized PowderMolecular weight:57.76 kDa (predicted); 82.52 kDa (reducing conditions)CSF1R Protein, Human, Recombinant (hFc)
CSF1R Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.Color and Shape:Lyophilized PowderMolecular weight:81.2 kDa (predicted)Ref: TM-TMPY-05429
5µg54.00€10µg85.00€20µg119.00€50µg231.00€100µg447.00€200µg655.00€500µg1,410.00€1mg2,777.00€CSF1R Protein, Human, Recombinant (His & Avi), Biotinylated
M-CSFR/CSF1R/CD115 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag.Color and Shape:Lyophilized PowderMolecular weight:57.4 kDa (predicted). Due to glycosylation, the protein migrates to 75-105 kDa based on Tris-Bis PAGE result.Ref: TM-TMPK-00415
5µg91.00€10µg150.00€20µg239.00€50µg471.00€100µg779.00€200µg1,410.00€500µg3,018.00€CSF1R Protein, Human, Recombinant
CSF1R Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 55.1 kDa and the accession number is P07333-1.Color and Shape:Lyophilized PowderMolecular weight:55.1 kDa (predicted); 80-90 kDa (reducing condition, due to glycosylation)CSF1R Protein, Human, Recombinant (mFc)
CSF1R Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag.Color and Shape:Lyophilized PowderMolecular weight:81.5 kDa (predicted)Ref: TM-TMPY-05264
5µg47.00€10µg65.00€20µg94.00€50µg167.00€100µg334.00€200µg499.00€500µg1,046.00€1mg2,099.00€CSF1R Protein, Human, Recombinant (Domain I&II&III, His)
CSF1R Protein, Human, Recombinant (Domain I&II&III, His) is expressed in HEK293 mammalian cells with His tag.Color and Shape:Lyophilized PowderMolecular weight:31.1 kDa (predicted)CSF1R Protein, Human, Recombinant (hFc & Avi), Biotinylated
CSF1R Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag.Color and Shape:Lyophilized PowderMolecular weight:83.04 kDa (predicted); 110.87 kDa (reducing conditions)CSF1R Protein (Ala299-Glu512), Human, Recombinant (His)
CSF1R Protein (Ala299-Glu512), Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.Color and Shape:Lyophilized PowderMolecular weight:25.3 kDa (predicted)CSF1R Protein, Human, Recombinant (His & Avi)
M-CSFR/CSF1R/CD115 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag.Color and Shape:Lyophilized PowderMolecular weight:57.4 kDa (predicted). Due to glycosylation, the protein migrates to 75-105 kDa based on Tris-Bis PAGE result.CSF1R Protein, Human, Recombinant (His & GST)
CSF1R Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag.Color and Shape:Lyophilized PowderMolecular weight:76 kDa (predicted); 75 kDa (reducing conditions)PLX5622
CAS:PLX5622 is a selective, orally active and blood-brain barrier permeable CSF1R inhibitor. PLX5622 induces elimination of microglia. Cost effective and quality assured.Formula:C21H19F2N5OPurity:98% - 99.97%Color and Shape:SolidMolecular weight:395.41Ref: TM-T7100
1mg43.00€1mL*10mM (DMSO)77.00€5mg81.00€10mg118.00€25mg230.00€50mg385.00€100mg502.00€200mg710.00€Seralutinib
CAS:Seralutinib (GB002) is an inhibitor of inhaled PDGFRα and PDGFRβ. It is used in the study for pulmonary arterial hypertension.Formula:C27H27N5O3Purity:99.09%Color and Shape:SolidMolecular weight:469.54Ref: TM-T8900
1mg47.00€2mg62.00€5mg92.00€1mL*10mM (DMSO)92.00€10mg137.00€25mg236.00€50mg313.00€100mg497.00€cFMS Receptor Inhibitor II
CAS:cFMS Receptor Inhibitor II is a CSF1R kinase inhibitorFormula:C23H20N4OPurity:99.8%Color and Shape:SolidMolecular weight:368.43Ref: TM-T5586
1mg47.00€2mg62.00€5mg92.00€1mL*10mM (DMSO)101.00€10mg145.00€25mg241.00€50mg356.00€100mg517.00€PF 477736
CAS:PF 477736 (PF-736,PF-00477736) is a specifc, effective and ATP-competitive Chk1 inhibitor (Ki: 0.49 nM ) and also inhibits FGFR3, Aurora-A, VEGFR2, Flt3, Fms (Formula:C22H25N7O2Purity:97.58% - 99.94%Color and Shape:SolidMolecular weight:419.48OSI-930
CAS:OSI-930 is an oral c-Kit/VEGFR-2 inhibitor targeting tumor growth and angiogenesis.Formula:C22H16F3N3O2SPurity:99.67%Color and Shape:SolidMolecular weight:443.44Sotuletinib
CAS:Sotuletinib (BLZ945) is an orally active, effective and specific CSF-1R inhibitor, >1000-fold selective against its closest receptor tyrosine kinase homologs.Formula:C20H22N4O3SPurity:97.43% - 99.82%Color and Shape:SolidMolecular weight:398.48Ref: TM-T6119
1mg34.00€5mg74.00€1mL*10mM (DMSO)82.00€10mg105.00€25mg163.00€50mg205.00€100mg358.00€500mg822.00€GW786034B
CAS:Pazopanib HCl (Votrient) inhibits VEGFR1-3, PDGFR, FGFR, c-Kit, c-Fms with IC50 range 10-146 nM in cell-free assays.Formula:C21H23N7O2S·HClPurity:99.87%Color and Shape:SolidMolecular weight:473.98Nampt-IN-1
CAS:Nampt-IN-1 (LSN3154567) (LSN3154567) is a potent and selective NAMPT inhibitor. Nampt-IN-1 inhibits purified NAMPT with an IC50 of 3.1 nM.Formula:C20H25N3O5SPurity:99.28% - 99.4%Color and Shape:SolidMolecular weight:419.49Ref: TM-T4376
1mg37.00€2mg49.00€5mg79.00€1mL*10mM (DMSO)87.00€10mg130.00€25mg245.00€50mg409.00€100mg605.00€PRN1371
CAS:PRN1371 is a specific and potent FGFR1-4 and CSF1R inhibitor (IC50s: 0.6/1.3/4.1/19.3/8.1 nM for FGFR1/2/3/4 and CSF1R).Formula:C26H30Cl2N6O4Purity:98.65%Color and Shape:SolidMolecular weight:561.46Ref: TM-TQ0015
1mg77.00€2mg100.00€5mg166.00€1mL*10mM (DMSO)200.00€10mg289.00€25mg492.00€50mg710.00€100mg973.00€GW2580
CAS:GW2580 (SC-203877) is a specific, oral-bioavailable CSF-1R inhibitor for c-FMS.Formula:C20H22N4O3Purity:99.48% - >99.99%Color and Shape:SolidMolecular weight:366.41AZD7507
CAS:AZD7507 is a CSF-1R inhibitor with an IC50 of 32 nM. AZD7507 has antitumor activity.Formula:C23H27FN6O3Purity:99.55% - 99.78%Color and Shape:SolidMolecular weight:454.5Ref: TM-T14380
1mg50.00€5mg110.00€1mL*10mM (DMSO)127.00€10mg161.00€25mg289.00€50mg419.00€100mg583.00€200mg787.00€Ki20227
CAS:Ki-20227 is a specific c-Fms tyrosine kinase(CSF1R) inhibitor (IC50: 2 nM).Formula:C24H24N4O5SPurity:98.97% - 99.88%Color and Shape:SolidMolecular weight:480.54Ref: TM-T4315
1mg44.00€5mg90.00€1mL*10mM (DMSO)90.00€10mg145.00€25mg268.00€50mg439.00€100mg700.00€200mg954.00€Edicotinib HCl
CAS:Edicotinib (JNJ-40346527), an oral CSF1R inhibitor, may block FMS autophosphorylation, impeding tumor cell growth.Formula:C27H36ClN5O2Color and Shape:SolidMolecular weight:498.07Dovitinib
CAS:Dovitinib is an orally active, multi-targeted tyrosine kinase (RTK) inhibitor with anti-tumor effects.Cost-effective and quality-assured.
Formula:C21H21FN6OPurity:99.35% - 99.92%Color and Shape:SolidMolecular weight:392.43Vimseltinib
CAS:Vimseltinib (DCC-3014) is a c-FMS (CSF-IR) and c-Kit dual inhibitor (IC50s: <0.01 μM and 0.1-1 μM).Formula:C23H25N7O2Purity:99.05% - 99.57%Color and Shape:SolidMolecular weight:431.49Ref: TM-T10652
1mg87.00€5mg178.00€1mL*10mM (DMSO)203.00€10mg295.00€25mg505.00€50mg690.00€100mg888.00€Linifanib
CAS:Linifanib (AL-39324) (ABT-869) is a novel, potent ATP-competitive VEGFR/PDGFR inhibitor for KDR (IC50: 4 nM), CSF-1R (IC50: 3 nM), Flt-1/3 (IC50: 3/4 nM) andFormula:C21H18FN5OPurity:98% - 98.24%Color and Shape:SolidMolecular weight:375.4Ref: TM-T2514
5mg48.00€1mL*10mM (DMSO)50.00€10mg80.00€25mg119.00€50mg178.00€100mg259.00€200mg477.00€500mg772.00€Pexidartinib
CAS:Pexidartinib (PLX-3397) is a capsule formulation containing a small-molecule receptor tyrosine kinase (RTK) inhibitor of KIT, CSF1R and FLT3 with potentialFormula:C20H15ClF3N5Purity:98.34% - 99.45%Color and Shape:SolidMolecular weight:417.81Ref: TM-T2115
5mg46.00€1mL*10mM (DMSO)49.00€10mg58.00€25mg90.00€50mg114.00€100mg145.00€200mg192.00€500mg333.00€Anumigilimab
CAS:Anumigilimab (CSL-324) is a fully human therapeutic anti-G-CSFR antibody with potential anti-tumor activity for the study of inflammation.Purity:95.75% (SEC-HPLC) - 98.43% (SEC-HPLC)Color and Shape:LiquidMolecular weight:143.86 kDaLenzilumab
CAS:Lenzilumab (KB 003) is a humanized GM-CSF neutralizing antibody for the study of COVID-19.Purity:98.9% (SDS-PAGE); 98.5% (SEC-HPLC) - 98.9% (SDS-PAGE); 98.5% (SEC-HPLC)Color and Shape:LiquidMolecular weight:146.81 kDaCerdulatinib hydrochloride
CAS:Cerdulatinib hydrochloride is an oral tyrosine kinase inhibitor targeting JAK1/2/3, TYK2, Syk, and 19 others with IC50 < 200 nM.Formula:C20H28ClN7O3SPurity:99.85%Color and Shape:SolidMolecular weight:482Trabikibart
CAS:Trabikibart (CSL311) is a human βc-specific antibody inhibiting IL-3, GM-CSF and IL-5, regulating eosinophil survival in chronic inflammatory disease research.Purity:95% - 95.6% (SDS-PAGE); 99.3% (SEC-HPLC)Color and Shape:LiquidMolecular weight:144.64 kDaNamilumab
CAS:Namilumab (AMG203) is a humanised IgG1 monoclonal antibody that neutralises GM-CSF. rheumatoid arthritis and active axial spondyloarthritis.Purity:95%Color and Shape:LiquidMolecular weight:~150 kDaAnti-Mouse GM-CSF Antibody (MP1-22E9)
Anti-Mouse GM-CSF Antibody is a rat-derived IgG2a isotype inhibitor that targets mouse granulocyte-macrophage colony-stimulating factor (GM-CSF).Purity:98%Color and Shape:Odour LiquidMolecular weight:150 kDaCabiralizumab
CAS:Cabiralizumab is an anti-CSF1R monoclonal antibody that enhances T cell infiltration, inhibits osteoclasts, and is used in RA and immune-oncology research.Purity:95% - 98.2% (SDS-PAGE); 98.1% (SEC-HPLC)Color and Shape:LiquidMolecular weight:146.30 kDaCSF1R-IN-19
CAS:CSF1R-IN-19 is a robust inhibitor of CSF1R that influences the exchange of inflammatory factors between TAMs and glioma cells. It holds potential for cancer research [1].Formula:C20H27N7OColor and Shape:SolidMolecular weight:381.47Sotuletinib dihydrochloride
CAS:Sotuletinib (BLZ945) dihydrochloride is an orally administered, blood-brain barrier-permeable inhibitor specifically targeting CSF1-R with an IC50 of 1 nM.Formula:C20H24Cl2N4O3SPurity:98%Color and Shape:SolidMolecular weight:471.4c-Fms-IN-9
CAS:c-Fms-IN-9 inhibits c-FMS/uFMS and uKIT with IC50 <0.01μM and 0.1-1μM, from patent WO2014145023A1.Formula:C21H23N7O2Purity:98%Color and Shape:SolidMolecular weight:405.45Leustroducsin A
CAS:Leustroducsin A is an inducer of colony-stimulating factors (CSFs) extracted from Streptomyces platensis SANK 60191.Formula:C32H52NO10PColor and Shape:SolidMolecular weight:641.73c-Fms-IN-7
CAS:c-Fms-IN-7 is a cFMS inhibitor (IC50: 18.5 nM).Formula:C26H24N6OSPurity:98%Color and Shape:SolidMolecular weight:468.57c-Fms-IN-8
CAS:c-Fms-IN-8 is a colony-stimulating factor-1 receptor (CSF-1R, c-FMS) Type II inhibitor (IC50: 9.1 nM). It is compound 4a in the reference.Formula:C27H30N2O5Purity:98%Color and Shape:SolidMolecular weight:462.54JNJ-28312141
CAS:JNJ-28312141: oral CSF1R/FLT3 inhibitor, potential for treating acute myeloid leukemia, tumors, and bone events.Formula:C26H32N6O2Purity:98%Color and Shape:SolidMolecular weight:460.57CSF1R-IN-4
CAS:CSF1R-IN-4, a potent CSF-1R inhibitor, may impact TAM/glioma cell communication, with cancer research potential. (WO2021197276A1, compound 104)Formula:C23H20N6O3Color and Shape:SolidMolecular weight:428.44c-Fms-IN-10
CAS:c-Fms-IN-10 is a thieno[3,2-d]pyrimidine derivative, an FMS kinase inhibitor with IC50 of 2 nM, exhibiting anti-tumor properties.Formula:C22H19N7OSPurity:98%Color and Shape:SolidMolecular weight:429.5CSF1R-IN-13
CAS:CSF1R-IN-13: potent cancer research CSF1R inhibitor impacting cell growth regulation.Formula:C21H20N4O3Color and Shape:SolidMolecular weight:376.41CSF1R-IN-8
CAS:CSF1R-IN-8 (Compound 22) is a CSF-1R inhibitor (IC50: 0.012 μM).Formula:C24H22N4O4Color and Shape:SolidMolecular weight:430.46CSF1R-IN-10
CAS:CSF1R-IN-10 (Compound 48) is a CSF-1R inhibitor (IC50: 0.005 μM).Formula:C25H22N4O3Color and Shape:SolidMolecular weight:426.47Leustroducsin C
CAS:Leustroducsin C is an inducer of colony-stimulating factors CSF extracted from Streptomyces platensis SANK 60191.Formula:C34H56NO10PColor and Shape:SolidMolecular weight:669.78CSF1R-IN-14
CAS:CSF1R-IN-14, an isoindolinone derivative, powerfully inhibits CSF1R, with potential in cancer research. See WO2019134662A1, compound 1.Formula:C23H22F3N5OColor and Shape:SolidMolecular weight:441.45CSF1R-IN-12
CAS:CSF1R-IN-12 is an effective CSF1R inhibitor. CSF1R-IN-12 has research potential in cancer diseases.Formula:C21H17F3N4OColor and Shape:SolidMolecular weight:398.38CSF1R-IN-7
CAS:CSF1R-IN-7 is a highly selective CSF-1R inhibitor with good brain penetration for treatment of diseases associated with microglia-mediated neuroinflammation.Formula:C22H22N6O3Purity:99.41% - 99.93%Color and Shape:SolidMolecular weight:418.45CSF1R-IN-9
CAS:CSF1R-IN-9 (Compound 46) is a CSF-1R inhibitor (IC50: 0.028 μM).Formula:C26H26N4O2Color and Shape:SolidMolecular weight:426.51CSF1R-IN-6
CAS:CSF1R-IN-6, a compound, effectively inhibits macrophage CSF1R essential for survival and differentiation.Formula:C20H18N8O3Color and Shape:SolidMolecular weight:418.41c-Fms-IN-2
CAS:c-Fms-IN-2 is an inhibitor of c-FMS kinase (IC50 = 24 nM).Formula:C19H21N3O3Purity:99.56%Color and Shape:SolidMolecular weight:339.39Ref: TM-T10775
1mg92.00€1mL*10mM (DMSO)180.00€5mg241.00€10mg355.00€25mg532.00€50mg750.00€100mg1,009.00€ABD-295
CAS:ABD-295, a biphenylsulfide derivative, inhibits osteoclasts and prevents bone loss in vitro and in vivo.Formula:C17H19F2NO3SPurity:98%Color and Shape:SolidMolecular weight:355.4c-Fms-IN-6
CAS:c-Fms-IN-6 is a potent inhibitor of c-FMS (IC50 ≤10 nM for unphosphorylated c-FMS) and also weakly inhibits unphosphorylated c-KIT and PDGFR (IC50: > 1 μM).Formula:C22H25N7O2Purity:98%Color and Shape:SolidMolecular weight:419.48IACS-9439
CAS:IACS-9439 is a potent, selective, and orally active inhibitor of CSF1R, exhibiting a K(i) of 1 nM.Formula:C23H26ClN7O3SPurity:98%Color and Shape:SolidMolecular weight:516.02c-Fms-IN-1
CAS:c-Fms-IN-1 is an inhibitor of c-FMS kinase (IC50 = 0.8 nM).Formula:C22H27N5O2Purity:99.94%Color and Shape:SolidMolecular weight:393.48Chiauranib
CAS:Chiauranib, a potent anticancer agent, inhibits angiogenesis kinases (VEGFR1-3, PDGFRα, c-Kit), Aurora B, and CSF1R with IC50 values of 1-9 nM.Formula:C27H21N3O3Purity:99.22%Color and Shape:SolidMolecular weight:435.47Ref: TM-T35570
1mg66.00€5mg144.00€1mL*10mM (DMSO)157.00€10mg245.00€25mg492.00€50mg710.00€100mg973.00€c-Fms-IN-3
CAS:c-Fms-IN-3 is a novel inhibitor of the c-FMS and can be used in studies about antirheumatic and anti-inflammatory diseases.Formula:C23H30N6OPurity:99.87%Color and Shape:SolidMolecular weight:406.52Ref: TM-T10649
1mg52.00€5mg105.00€1mL*10mM (DMSO)110.00€10mg161.00€25mg264.00€50mg358.00€100mg522.00€c-Fms-IN-13
CAS:c-Fms-IN-13 (compound 14) is a potent FMS kinase inhibitor (IC50= 17 nM). c-Fms-IN-13 is an anti-inflammatory agent.Formula:C22H26N4O2Purity:99.93% - 99.97%Color and Shape:SolidMolecular weight:378.47Pimicotinib
CAS:Pimicotinib (ABSK021) is a potent CSF1R inhibitor with antitumor activity and can be used to study advanced solid tumors.Formula:C22H24N6O3Purity:99.8%Color and Shape:SolidMolecular weight:420.46Ref: TM-T79157
1mg52.00€5mg111.00€1mL*10mM (DMSO)156.00€10mg170.00€25mg329.00€50mg528.00€100mg843.00€CSF1R-IN-3
CAS:CSF1R-IN-3 is an orally effective CSF-1R inhibitor with an IC50 value of 2.1 nM.Formula:C30H38N8O4Purity:98.4%Color and Shape:SolidMolecular weight:574.67Ref: TM-T64066
1mg101.00€5mg245.00€1mL*10mM (DMSO)309.00€10mg358.00€25mg665.00€50mg973.00€100mg1,395.00€Ataquimast
CAS:Ataquimast is used in curing advanced receptor-positive breast cancer.Formula:C11H14ClN3OPurity:99.92%Color and Shape:SolidMolecular weight:239.7Ref: TM-T30190
1mg64.00€1mL*10mM (DMSO)116.00€5mg129.00€10mg188.00€25mg299.00€50mg427.00€100mg575.00€200mg750.00€JTE-952
CAS:JTE-952: oral, selective Type II CSF-1R inhibitor, IC50 = 13 nM for CSF1R, 261 nM for TrkA, effective in mouse arthritis model.Formula:C30H34N2O6Purity:98%Color and Shape:SolidMolecular weight:518.6c-Fms-IN-14
CAS:c-Fms-IN-14 (Example 76) is a potent inhibitor of the c-Fms kinase with an IC50 of 4 nM, utilized in cancer and autoimmune disease research [1].Formula:C26H24N6OPurity:98%Color and Shape:SolidMolecular weight:436.51Axl/Mer/CSF1R-IN-2
CAS:Axl/Mer/CSF1R-IN-2 (Comp 4) serves as an inhibitor for Axl, Mer, and CSF1R [1].Formula:C24H22F3N5O5Color and Shape:SolidMolecular weight:517.46CSF1R-IN-5
CAS:CSF1R-IN-5: Potent CSF1R inhibitor, may alter TAM/glioma inflammatory exchanges, potential cancer research tool. (WO2021197276A1, Compound 11)Formula:C22H19N7O3Color and Shape:SolidMolecular weight:429.43
