VEGFR
VEGFR (Vascular Endothelial Growth Factor Receptor) inhibitors are compounds that block the signaling of VEGFR, a key receptor in the VEGF pathway, which is crucial for angiogenesis. VEGFR inhibitors prevent the formation of new blood vessels that supply nutrients and oxygen to tumors, thereby inhibiting tumor growth. These inhibitors are widely used in cancer therapy and research to study the mechanisms of angiogenesis and develop anti-cancer treatments. At CymitQuimica, we provide a comprehensive range of high-quality VEGFR inhibitors to support your research in oncology, vascular biology, and angiogenesis.
Found 268 products of "VEGFR"
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Cabozantinib S-malate
CAS:<p>Cabozantinib S-malate (XL184) is the salt form of cabozantinib, an orally bioavailable, small molecule RTK inhibitor with potential antineoplastic activity.</p>Formula:C32H30FN3O10Purity:98% - >99.99%Color and Shape:SolidMolecular weight:635.59SU5214
CAS:<p>SU5214 is a modulator of tyrosine kinase signal transduction.</p>Formula:C16H13NO2Purity:99.45% - 99.55%Color and Shape:SolidMolecular weight:251.28UNC0064-12 hydrochloride (1430089-64-7(free base))
<p>UNC0064-12 hydrochloride is an inhibitor of VEGFR2.</p>Formula:C19H25ClN8Purity:99.52%Color and Shape:SolidMolecular weight:400.91Toceranib Phosphate
CAS:<p>Toceranib Phosphate (SU11654 phosphate), is a selective inhibitor of the tyrosine kinase activity of several members of the split kinase RTK family.</p>Formula:C22H28FN4O6PPurity:98.56%Color and Shape:SolidMolecular weight:494.45Ramucirumab
CAS:<p>Ramucirumab is a human VEGFR-2 antagonist for the treatment of solid tumors.</p>Formula:C285H434N74O88S2Purity:98.2% (SDS-PAGE); 99.2% (SEC-HPLC) - 99.20%Color and Shape:LiquidMolecular weight:143.77 kDaNingetinib
CAS:<p>Ningetinib (CT-053) (CT053PTSA) is an orally bioavailable tyrosine kinase inhibitor with IC50s of <1.0, 1.9 and 6.7 nM for Axl, VEGFR2, and c-Met, respectively.</p>Formula:C31H29FN4O5Purity:99.95% - 99.98%Color and Shape:SolidMolecular weight:556.58Orobol
CAS:<p>Orobol (3’,4’,5,7-tetrahydroxy-isoflavon) is an inhibitor of tyrosine-specific protein kinase and phosphatidylinositol turnover.</p>Formula:C15H10O6Purity:98% - 98%Color and Shape:SolidMolecular weight:286.24XL 999
CAS:<p>Tyrosine kinase-IN-1 is a multi-targeted tyrosine kinase inhibitor（KDR, Flt-1, FGFR1 and PDGFRα with IC50s of 4nM, 20nM, 4nM, 2 nM ,respectively）</p>Formula:C26H28FN5OPurity:98.24% - 99.55%Color and Shape:SolidMolecular weight:445.53Cabozantinib
CAS:<p>Cabozantinib (XL184) is a multi-targeted tyrosine kinase receptor inhibitor that inhibits VEGFR2, c-Met, Kit, Axl, and Flt3 (IC50=0.035/1.3/4.6/7/11.3 nM).</p>Formula:C28H24FN3O5Purity:99.68% - 99.88%Color and Shape:SolidMolecular weight:501.51BFH772
CAS:<p>BFH772, a BAW2881 analogue, selectively inhibits VEGFR2 (IC50: 3 nM) and blocks RET, PDGFR, KIT phosphorylation (IC50: 30-160 nM).</p>Formula:C23H16F3N3O3Purity:97.71% - 99.36%Color and Shape:SolidMolecular weight:439.39Su1498
CAS:<p>Su1498 (Tyrphostin SU 1498) is a selective inhibitor of the VEGF receptor 2, having negligible activity at several other serine/threonine and tyrosine kinases.</p>Formula:C25H30N2O2Purity:99.54%Color and Shape:SolidMolecular weight:390.52Regorafenib Hydrochloride
CAS:<p>Regorafenib HCl (BAY73-4506) is an oral inhibitor targeting angiogenic, stromal, and cancer kinases with strong antitumor effects.</p>Formula:C21H16Cl2F4N4O3Purity:99.56%Color and Shape:SolidMolecular weight:519.28Tesevatinib
CAS:<p>Tesevatinib (XL-647) is an oral, multi-targeted tyrosine kinase inhibitor.Cost-effective and quality-assured.</p>Formula:C24H25Cl2FN4O2Purity:97.89% - 98.66%Color and Shape:SolidMolecular weight:491.39NVP-ACC789
CAS:<p>ACC-789 (NVP-ACC789 (ZK202650); ZK-202650) is an effective, specific and orally active inhibitor of the VEGF receptor tyrosine kinases.</p>Formula:C21H17BrN4Purity:99.44% - 99.63%Color and Shape:SolidMolecular weight:405.29Alectinib
CAS:<p>Alectinib (RG-7853) is an ALK inhibitor that is selective, orally active, and ATP-competitive. Alectinib has antitumor activity. Cost-effective and quality-assured.</p>Formula:C30H34N4O2Purity:98% - 99.38%Color and Shape:SolidMolecular weight:482.62BMS-2
CAS:<p>BMS-2 is a Met/Flt-3/VEGFR2 tyrosine kinase inhibitor.</p>Formula:C25H16F2N4O3Purity:98.33%Color and Shape:SolidMolecular weight:458.42Nintedanib
CAS:<p>Nintedanib (Intedanib) is a triple vascular kinase inhibitor that inhibits VEGFR1, VEGFR2, and VEGFR3 (IC50=34/13/13 nM), FGFR1, FGFR2, and FGFR3 (IC50=69/37/</p>Formula:C31H33N5O4Purity:98% - 99.92%Color and Shape:SolidMolecular weight:539.62Mollugin
CAS:<p>Mollugin could be a JAK2 inhibitor, anti-inflammatory, chemotherapeutic agent in OSCCs, bone disorder therapy, and modulates HER2 in cancer.</p>Formula:C17H16O4Purity:99.87% - ≥95%Color and Shape:SolidMolecular weight:284.31Cabozantinib hydrochloride
CAS:<p>Cabozantinib hydrochloride (XL184) is a potent pan-tyrosine kinases inhibitor that inhibits VEGFR2, c-Met, Kit, Axl, and Flt4 (IC50s: 0.035, 1.3, 4.6, 7 and 6</p>Formula:C28H25ClFN3O5Purity:99.97%Color and Shape:SolidMolecular weight:537.96JK-P3
CAS:<p>JK-P3: a pyrazole inhibitor of VEGFR-2 (IC50: 7.8 μM), stalls FGFR 1/3 in vitro, halts HUVEC wound healing/tube formation, not cell growth.</p>Formula:C18H17N3O3Purity:99.57%Color and Shape:SolidMolecular weight:323.35Dovitinib
CAS:<p>Dovitinib is an orally active, multi-targeted tyrosine kinase (RTK) inhibitor with anti-tumor effects.Cost-effective and quality-assured.</p>Formula:C21H21FN6OPurity:99.35% - 99.92%Color and Shape:SolidMolecular weight:392.43ODM-203
CAS:<p>ODM-203, a Selective Inhibitor of FGFR and VEGFR, Shows Strong Antitumor Activity, and Induces Antitumor Immunity</p>Formula:C26H21F2N5O2SPurity:99.85%Color and Shape:SolidMolecular weight:505.54Sitravatinib
CAS:<p>Sitravatinib (MGCD516) (MGCD516) is an inhibitor targeting multiple RTKs involved in driving sarcoma cell growth, including c-Met, c-Kit, PDGFRα/β, PDGFR, and</p>Formula:C33H29F2N5O4SPurity:98.9% - 99.85%Color and Shape:SolidMolecular weight:629.684SC-203
CAS:<p>4SC-203 is a multi-kinase inhibitor with potential anti-tumor activity.Cost-effective and quality-assured.</p>Formula:C33H38N8O4SPurity:96.4% - 99.67%Color and Shape:SolidMolecular weight:642.77hVEGF-IN-1
CAS:<p>hVEGF-IN-1 inhibits human VEGF-A translation and has antitumor activity.</p>Formula:C34H43N7O2Purity:99.76% - >99.99%Color and Shape:SolidMolecular weight:581.75ENMD-2076
CAS:<p>ENMD-2076, a multi-targeted kinase inhibitor, has specific activity against Aurora A, Flt3, KDR/VEGFR2, Flt4/VEGFR3, FGFR1, FGFR2, Src, PDGFRα.</p>Formula:C21H25N7Purity:97.63% - ≥95%Color and Shape:SolidMolecular weight:375.47SPHINX31
CAS:<p>SPHINX31 is a potent inhibitor of serine/arginine-rich protein kinase 1 (SRPK1; IC50: 5.9 nM).</p>Formula:C27H24F3N5O2Purity:98.81% - 99.3%Color and Shape:SolidMolecular weight:507.51AST 487
CAS:<p>AST 487 (NVP-AST 487) is a RET kinase inhibitor, inhibiting RET autophosphorylation and activation of downstream effectors. It also can inhibit Flt-3.</p>Formula:C26H30F3N7O2Purity:98.17% - 99.56%Color and Shape:SolidMolecular weight:529.56Tivozanib hydrochloride hydrate
CAS:<p>Tivozanib hydrochloride hydrate (AV-951 hydrochloride hydrate) is a VEGFR tyrosine kinase inhibitor that inhibits VEGFR-1, VEGFR-2, VEGFR-3 .</p>Formula:C22H22Cl2N4O6Purity:98.66%Color and Shape:SolidMolecular weight:509.34Toceranib
CAS:<p>Toceranib phosphate, orally active, inhibits RTK, PDGFR, VEGFR, Kit; Kis 5 nM PDGFRβ, 6 nM KDR; has antitumor effects.</p>Formula:C22H25FN4O2Purity:97.14%Color and Shape:SolidMolecular weight:396.46(Rac)-SAR131675
CAS:<p>(Rac)-SAR131675 is an effective and specific VEGFR-3 inhibitor, which inhibited VEGFR-3 tyrosine kinase activity and VEGFR-3 autophosphorylation in HEK cells.</p>Formula:C18H22N4O4Purity:98.34% - 99.1%Color and Shape:SolidMolecular weight:358.39BIBF 1202
CAS:<p>BIBF 1202 is a VEGFR2 kinase inhibitor (IC50 = 62 nM).</p>Formula:C30H31N5O4Purity:98.04%Color and Shape:SolidMolecular weight:525.6BMS-690514
CAS:<p>BMS-690514 is a potent and orally active inhibitor of EGFR and VEGFR. It has IC50s of 5, 20 and 60 nM for EGFR, HER 2 and HER 4, respectively.</p>Formula:C19H24N6O2Purity:99.08%Color and Shape:SolidMolecular weight:368.43Brivanib (alaninate)
CAS:<p>Brivanib Alaninate (BMS-582664) is an alaninate salt of a vascular endothelial growth factor receptor 2 (VEGFR2) inhibitor with potential antineoplastic effect.</p>Formula:C22H24FN5O4Purity:99.46% - 99.66%Color and Shape:SolidMolecular weight:441.46Anti-Mouse VEGFR-2 Antibody (DC101)
<p>Anti-Mouse VEGFR-2 Antibody (DC101) is a rat-derived monoclonal antibody against mouse VEGFR2/KDR/Flk-1, serving as a mouse analogue of ramucirumab.</p>Purity:99%Color and Shape:Odour LiquidTarcocimab
CAS:<p>Tarcocimab (OG1953) is a humanized IgG1 monoclonal antibody targeting VEGFA, researched for RVO and wet AMD.</p>Color and Shape:LiquidZM323881 hydrochloride
CAS:<p>ZM323881 hydrochloride (ZM 323881 HCl) is a potent and selective VEGFR2 inhibitor.</p>Formula:C22H19ClFN3O2Purity:99.43%Color and Shape:SolidMolecular weight:411.86Dovitinib Dilactic Acid
CAS:<p>Dovitinib dilactic acid: multitarget RTK inhibitor for FLT3/c-Kit (IC50=1-2 nM), FGFR1/3, VEGFR1-4 (IC50=8-13 nM), less effective on InsR, EGFR. Phase 4.</p>Formula:C21H21FN6O·2C3H6O3Purity:98%Color and Shape:SolidMolecular weight:572.59Bucillamine
CAS:<p>Bucillamine (DE019) protects against Ischemia/reperfusion injury in high-risk organ transplants and inhibits the production of VEGF.</p>Formula:C7H13NO3S2Purity:99.47%Color and Shape:SolidMolecular weight:223.31E3330
CAS:<p>E3330 is a potent and selective APE1(Ref-1) inhibitor, which suppressed NF-kappa B DNA-binding activity.</p>Formula:C21H30O6Purity:99.52%Color and Shape:SolidMolecular weight:378.46GW843682X
CAS:<p>GW843682X (GW843682) is a selective and ATP-competitive inhibitor of PLK1 and PLK3 (IC50s = 2.2 nM and 9.1 nM).</p>Formula:C22H18F3N3O4SPurity:99.92%Color and Shape:SolidMolecular weight:477.46CP-547632
CAS:<p>CP-547632 is an oral ATP-competitive inhibitor of VEGFR-2/FGF kinase with IC50s of 11/9 nM, highly selective, has antitumor activity.</p>Formula:C20H24BrF2N5O3SPurity:99.39%Color and Shape:SolidMolecular weight:532.4DMH4
CAS:<p>DMH4 is a potent and selective inhibitor of VEGFR2 with an IC50 of 0.16 µM.</p>Formula:C24H24N4O2Purity:99.58%Color and Shape:SolidMolecular weight:400.47AMG-Tie2-1
CAS:<p>AMG-Tie2-1 is a Tie2 and VEGFR2 inhibitor with anticancer and antitumor activity for the study of cardiovascular disease and cancer.</p>Formula:C25H20F3N5O2Purity:98.9%Color and Shape:SolidMolecular weight:479.45VEGFR-2-IN-6
CAS:<p>VEGFR-2-IN-6 (WO 02/059110, example 64) is a potent inhibitor of VEGFR2, a crucial receptor involved in the regulation of angiogenesis [1].</p>Formula:C20H21N7O2SPurity:99.01%Color and Shape:SolidMolecular weight:423.49MMPP
CAS:<p>MMPP is a VEGFR2 inhibitor with anti-inflammatory activity, inhibits STAT3 , inhibits angiogenesis, and can be used to alleviate myocardial injury.</p>Formula:C17H18O3Purity:99.31% - 99.83%Color and Shape:SolidMolecular weight:270.32Naphazoline
CAS:<p>Naphazoline (Naphcon-a) is a sympathomimetic compound with marked alpha adrenergic activity.</p>Formula:C14H14N2Purity:99.79%Color and Shape:White Crystalline Powder SolidMolecular weight:210.27Ansornitinib
CAS:<p>Ansornitinib (ANG-3070) is a KDR and PDGF receptor inhibitor with antifibrotic activity for the study of diseases caused by abnormal or excessive fibrosis.</p>Formula:C30H32N6O4Color and Shape:SolidMolecular weight:540.61CGP60474
CAS:<p>CGP60474 is an inhibitor of VEGFR-2 (IC50 = 84 nM) and an inhibitor of ATP-competitive PKC.</p>Formula:C18H18ClN5OPurity:98.81%Color and Shape:SolidMolecular weight:355.82AMPK-IN-3
CAS:<p>AMPK-IN-3: potent, selective AMPK (α2/α1) & KDR inhibitor; IC50: 60.7/107/3820 nM; anticancer in K562 cells.</p>Formula:C25H33N5O3Purity:99.13%Color and Shape:SolidMolecular weight:451.56VEGFR-3-IN-1
CAS:<p>VEGFR-3-IN-1, a potent VEGFR3 inhibitor (IC50=110.4 nM), hinders tumor growth and VEGFR3 signaling, affecting HDLEC and MDA-MB cell proliferation/migration.</p>Formula:C29H29ClF3N7OSPurity:99.95%Color and Shape:SolidMolecular weight:616.1Pz-1
CAS:<p>Pz-1 is an inhibitor of VEGFR2 and RET (rearranged during transfection) tyrosine kinase that blocks the blood supply required for RET-stimulated growth.</p>Formula:C26H26N6O2Purity:99.89%Color and Shape:SolidMolecular weight:454.52Chiauranib
CAS:<p>Chiauranib, a potent anticancer agent, inhibits angiogenesis kinases (VEGFR1-3, PDGFRα, c-Kit), Aurora B, and CSF1R with IC50 values of 1-9 nM.</p>Formula:C27H21N3O3Purity:99.22%Color and Shape:SolidMolecular weight:435.47(Z)-FeCP-oxindole
CAS:<p>(Z)-FeCP-oxindole is a selective inhibitor of VEGFR2 with an IC50 of 200 nM for human. (Z)-FeCP-oxindole shows anticancer activity.</p>Formula:C19H15FeNOPurity:99.63% - 99.84%Color and Shape:SolidMolecular weight:329.17(E)-FeCP-oxindole
CAS:<p>(E)-FeCP-oxindole 是一种 VEGFR2 抑制剂，IC50 为 214 nM。</p>Formula:C19H15FeNOPurity:99.85%Color and Shape:SolidMolecular weight:329.17Tyrphostin AG1433
CAS:<p>Tyrphostin AG1433 (AG1433) is an inhibitor of tyrosine kinases and also a dual inhibitor of PDGFRβ(IC50s = 5.0 μM) and VEGFR-2 (Flk-1/KDR)(IC50s = 9.3 μM).</p>Formula:C16H14N2O2Purity:98.47%Color and Shape:SolidMolecular weight:266.29TIE-2/VEGFR-2 kinase-IN-5
CAS:<p>TIE-2/VEGFR-2 kinase-IN-5 is a TIE-2 and VEGFR-2 tyrosine kinase receptor inhibitor commonly used in biomedical research related to angiogenesis.</p>Formula:C21H13F6N5O2Purity:99.79%Color and Shape:SolidMolecular weight:481.35Brolucizumab
CAS:<p>Brolucizumab (anti-VEGF-A scFv) potently blocks VEGF-A to reduce neovascularization in wet AMD, with picomolar binding affinity.</p>Purity:95%Color and Shape:LiquidTG 100572 Hydrochloride
CAS:<p>TG 100572 Hydrochloride is a inhibitor of multi-targeted kinase which inhibits receptor tyrosine kinases and Src kinases(IC50s of 2, 7, 2, 16, 13, 5, 0.5, 6, 0.</p>Formula:C26H27Cl2N5O2Purity:98%Color and Shape:SolidMolecular weight:512.43AKB-6899
CAS:<p>AKB-6899 is an inhibitor of prolyl hydroxylase domain 3 (PHD3) and increases the soluble form of the VEGF receptor (sVEGFR-1) production from GM-CSF-treated</p>Formula:C14H11FN2O4Purity:97.87%Color and Shape:SolidMolecular weight:290.25VEGFR-2-IN-9
CAS:<p>VEGFR-2-IN-9 (KDR-in-4) is a potent KDR/VEGFR2 inhibitor (IC50: 7 nM). It can be used to study breast cancer.</p>Formula:C23H25N3O3Purity:97.19%Color and Shape:SolidMolecular weight:391.46VEGFR-2-IN-37
CAS:<p>VEGFR-2-IN-37 (compound 12), a VEGFR-2 inhibitor, exhibits an inhibition rate of approximately 56.9 μM at a concentration of 200 μM.</p>Formula:C18H16N2O2SPurity:98%Color and Shape:SolidMolecular weight:324.4VEGFR2-IN-3
CAS:<p>VEGFR2-IN-3 (compound 385) is a potent inhibitor of VEGFR2 [1].</p>Formula:C26H28ClN5O4Purity:98%Color and Shape:SolidMolecular weight:509.98WAY-600
CAS:<p>WAY-600 is a potent, ATP-competitive and selective inhibitor of mTOR with IC50 of 9 nM; blocks mTORC1/P-S6K(T389) and mTORC2/P-AKT(S473) but not P-AKT(T308).</p>Formula:C28H30N8OPurity:99.88%Color and Shape:SolidMolecular weight:494.59VEGFR2-IN-1
CAS:<p>VEGFR2-IN-1 is a VEGFR2 inhibitor with antitumor activity used in the study of breast cancer.</p>Formula:C22H18N6SPurity:98.15%Color and Shape:SolidMolecular weight:398.48Lucitanib dihydrochloride
CAS:<p>Lucitanib dihydrochloride (E-3810 dihydrochloride) is an efficient VEGFR1-3, FGFR1-3, and PDGFRalpha/β inhibitor, used in metastatic breast cancer research.</p>Formula:C26H27Cl2N3O4Color and Shape:SolidMolecular weight:516.42VEGFR/PDGFR-IN-1
CAS:<p>VEGFR/PDGFR-IN-1 (Compound 1) is an inhibitor of VEGFR with an IC50 of 0.4 μM. It can inhibit angiogenesis in HUVEC cells and holds promise for impeding tumor growth and metastasis.</p>Formula:C17H21N5O3Color and Shape:SolidMolecular weight:343.38VEGFR-2-IN-65
CAS:<p>VEGFR-2-IN-65 (Compound 07) functions as a VEGFR-2 inhibitor. It forms hydrogen bonds with Cys180 and can inhibit tube formation in HUVECs.</p>Formula:C21H18N2O3Color and Shape:SolidMolecular weight:346.379
