VEGFR
VEGFR (Vascular Endothelial Growth Factor Receptor) inhibitors are compounds that block the signaling of VEGFR, a key receptor in the VEGF pathway, which is crucial for angiogenesis. VEGFR inhibitors prevent the formation of new blood vessels that supply nutrients and oxygen to tumors, thereby inhibiting tumor growth. These inhibitors are widely used in cancer therapy and research to study the mechanisms of angiogenesis and develop anti-cancer treatments. At CymitQuimica, we provide a comprehensive range of high-quality VEGFR inhibitors to support your research in oncology, vascular biology, and angiogenesis.
Found 256 products for "VEGFR".
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Toceranib Phosphate
CAS:Toceranib Phosphate (SU11654 phosphate), is a selective inhibitor of the tyrosine kinase activity of several members of the split kinase RTK family.Formula:C22H28FN4O6PPurity:98.56%Color and Shape:SolidMolecular weight:494.45CZC-8004
CAS:CZC-8004 (CZC-00008004) is a pan-kinase(ABL kinase) inhibitor and binds a range of tyrosine kinases.Formula:C17H16FN5Purity:99.29%Color and Shape:SolidMolecular weight:309.34Nintedanib
CAS:Nintedanib (Intedanib) is a triple vascular kinase inhibitor that inhibits VEGFR1, VEGFR2, and VEGFR3 (IC50=34/13/13 nM), FGFR1, FGFR2, and FGFR3 (IC50=69/37/Formula:C31H33N5O4Purity:98% - 99.92%Color and Shape:SolidMolecular weight:539.62Mollugin
CAS:Mollugin could be a JAK2 inhibitor, anti-inflammatory, chemotherapeutic agent in OSCCs, bone disorder therapy, and modulates HER2 in cancer.Formula:C17H16O4Purity:99.87% - ≥95%Color and Shape:SolidMolecular weight:284.31Cabozantinib hydrochloride
CAS:Cabozantinib hydrochloride (XL184) is a potent pan-tyrosine kinases inhibitor that inhibits VEGFR2, c-Met, Kit, Axl, and Flt4 (IC50s: 0.035, 1.3, 4.6, 7 and 6Formula:C28H25ClFN3O5Purity:99.97%Color and Shape:White SolidMolecular weight:537.96Ref: TM-T5164
1mg42.00€2mg52.00€5mg65.00€10mg92.00€25mg160.00€50mg235.00€100mg330.00€200mg538.00€500mg860.00€JK-P3
CAS:JK-P3: a pyrazole inhibitor of VEGFR-2 (IC50: 7.8 μM), stalls FGFR 1/3 in vitro, halts HUVEC wound healing/tube formation, not cell growth.Formula:C18H17N3O3Purity:99.57%Color and Shape:SolidMolecular weight:323.35Dovitinib
CAS:Dovitinib is an orally active, multi-targeted tyrosine kinase (RTK) inhibitor with anti-tumor effects.Cost-effective and quality-assured.
Formula:C21H21FN6OPurity:99.35% - 99.92%Color and Shape:SolidMolecular weight:392.43ODM-203
CAS:ODM-203, a Selective Inhibitor of FGFR and VEGFR, Shows Strong Antitumor Activity, and Induces Antitumor ImmunityFormula:C26H21F2N5O2SPurity:99.85%Color and Shape:White SolidMolecular weight:505.54Sitravatinib
CAS:Sitravatinib (MGCD516) (MGCD516) is an inhibitor targeting multiple RTKs involved in driving sarcoma cell growth, including c-Met, c-Kit, PDGFRα/β, PDGFR, andFormula:C33H29F2N5O4SPurity:98.9% - 99.85%Color and Shape:SolidMolecular weight:629.68Ref: TM-T4349
5mg49.00€1mL*10mM (DMSO)69.00€10mg74.00€25mg130.00€50mg200.00€100mg319.00€200mg507.00€500mg800.00€4SC-203
CAS:4SC-203 is a multi-kinase inhibitor with potential anti-tumor activity.Cost-effective and quality-assured.Formula:C33H38N8O4SPurity:99.52% - 99.98%Color and Shape:SolidMolecular weight:642.77hVEGF-IN-1
CAS:hVEGF-IN-1 inhibits human VEGF-A translation and has antitumor activity.Formula:C34H43N7O2Purity:99.76% - >99.99%Color and Shape:SolidMolecular weight:581.75ENMD-2076
CAS:ENMD-2076, a multi-targeted kinase inhibitor, has specific activity against Aurora A, Flt3, KDR/VEGFR2, Flt4/VEGFR3, FGFR1, FGFR2, Src, PDGFRα.Formula:C21H25N7Purity:97.63% - 99.86%Color and Shape:SolidMolecular weight:375.47SPHINX31
CAS:SPHINX31 is a potent inhibitor of serine/arginine-rich protein kinase 1 (SRPK1; IC50: 5.9 nM).Formula:C27H24F3N5O2Purity:99.3% - 99.87%Color and Shape:SolidMolecular weight:507.51Ref: TM-T5194
1mg38.00€5mg79.00€10mg92.00€1mL*10mM (DMSO)93.00€25mg170.00€50mg255.00€100mg408.00€500mg945.00€AST 487
CAS:AST 487 (NVP-AST 487) is a RET kinase inhibitor, inhibiting RET autophosphorylation and activation of downstream effectors. It also can inhibit Flt-3.Formula:C26H30F3N7O2Purity:98.17% - 99.56%Color and Shape:SolidMolecular weight:529.56Ref: TM-T4053
1mg34.00€2mg49.00€5mg74.00€1mL*10mM (DMSO)87.00€10mg113.00€25mg177.00€50mg334.00€100mg500.00€500mg1,099.00€VEGFR-2-IN-5
CAS:VEGFR-2-IN-5 (UNC0064-12), multikinase inhibitor and has a -NH2 terminal linker for further synthesis.Formula:C19H24N8Purity:99.92%Color and Shape:SolidMolecular weight:364.45PD173074
CAS:PD173074 inhibits FGFR1 (IC50: 25 nM) and VEGFR2 (100-200 nM); ~1000x more selective for FGFR1 over PDGFR/c-Src.Formula:C28H41N7O3Purity:97.27% - 98.15%Color and Shape:SolidMolecular weight:523.67Ref: TM-T2642
5mg40.00€1mL*10mM (DMSO)46.00€10mg54.00€25mg94.00€50mg133.00€100mg210.00€200mg371.00€500mg620.00€TAK-593
CAS:TAK-593 is an effective VEGFR and PDGFR family inhibitor (IC50s: 3.2, 0.95, 1.1, 4.3, and 13 nM for VEGFR1, VEGFR2, VEGFR3, PDFGRα, and PDFGRβ, respectively).Formula:C23H23N7O3Purity:99.37%Color and Shape:SolidMolecular weight:445.47Ref: TM-T16975
2mg42.00€5mg62.00€1mL*10mM (DMSO)73.00€10mg96.00€25mg182.00€50mg284.00€100mg409.00€200mg575.00€Bevacizumab
CAS:Ipilimumab targets CTLA-4, an immune checkpoint inhibitor. Bevacizumab binds to VEGF-A isoforms.Purity:95.40% - CE-SDS:97.5% SEC-HPLC:98.0%Color and Shape:Transparent LiquidMolecular weight:146.53 kDaIsolinderalactone
CAS:Isolinderalactone shows anti-inflammatory and anticancer capacity, and it exhibits moderate iNOS inhibitory activity, with the IC50 value of 0.30 uM.Formula:C15H16O3Purity:98.76%Color and Shape:SolidMolecular weight:244.29Vandetanib
CAS:Vandetanib (ZD6474) is a potent inhibitor of VEGFR2 (IC50: 40 nM). It also inhibits VEGFR3 and EGFR.Formula:C22H24BrFN4O2Purity:99.7% - 99.99%Color and Shape:White SolidMolecular weight:475.35Ref: TM-T1656
1mL*10mM (DMSO)34.00€10mg50.00€25mg65.00€50mg92.00€100mg166.00€200mg224.00€500mg359.00€
