VEGFR
VEGFR (Vascular Endothelial Growth Factor Receptor) inhibitors are compounds that block the signaling of VEGFR, a key receptor in the VEGF pathway, which is crucial for angiogenesis. VEGFR inhibitors prevent the formation of new blood vessels that supply nutrients and oxygen to tumors, thereby inhibiting tumor growth. These inhibitors are widely used in cancer therapy and research to study the mechanisms of angiogenesis and develop anti-cancer treatments. At CymitQuimica, we provide a comprehensive range of high-quality VEGFR inhibitors to support your research in oncology, vascular biology, and angiogenesis.
Found 268 products of "VEGFR"
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Fruquintinib
CAS:<p>Fruquintinib (HMPL-013) is an orally available, small molecule inhibitor of vascular endothelial growth factor receptors (VEGFRs), with potential anti-</p>Formula:C21H19N3O5Purity:98.84% - 99.89%Color and Shape:SolidMolecular weight:393.39Orantinib
CAS:<p>Orantinib (NSC 702827) , a excellent effective against PDGFR autophosphorylation with Ki of 8 nM, also highly inhibits Flk-1 and FGFR1 trans-phosphorylation.</p>Formula:C18H18N2O3Purity:98.92% - 99.52%Color and Shape:SolidMolecular weight:310.35AG-13958
CAS:<p>AG-13958 (AG-013958) (AG-013958), a potent VEGFR tyrosine kinase inhibitor, for the treatment of age-related macular degeneration.</p>Formula:C26H22FN7OPurity:99.4%Color and Shape:SolidMolecular weight:467.5Motesanib
CAS:<p>Motesanib (AMG 706) orally blocks VEGFR, PDGFR, Kit, Ret; curbing angiogenesis and cancer cell growth.</p>Formula:C22H23N5OPurity:98% - 99.09%Color and Shape:SolidMolecular weight:373.45KRN-633
CAS:<p>KRN-633 is an effective VEGFR inhibitor. The IC50s of KRN-633(KRN633) for VEGFR1, VEGFR2, and VEGFR3 is 170, 160 and 125 nM, respectively.</p>Formula:C20H21ClN4O4Purity:99.53% - 99.73%Color and Shape:SolidMolecular weight:416.86JI-101
CAS:<p>JI-101 (CGI-1842) is an oral multi-kinase inhibitor that targets VEGFR-2, PDGFR-β, and EphB4.</p>Formula:C22H20BrN5O2Purity:99.41% - 99.97%Color and Shape:SolidMolecular weight:466.33Ilorasertib
CAS:<p>Ilorasertib (ABT-348) inhibits Aurora kinases A/B/C & RET, PDGFRβ, Flt1 (IC50: 1-120 nM).</p>Formula:C25H21FN6O2SPurity:96.17% - 97.49%Color and Shape:SolidMolecular weight:488.54Cediranib
CAS:<p>Cediranib (AZD2171) is a potent KDR tyrosine kinase inhibitor (IC50 < 1nM), also targets Flt1/4, PDGFRβ, c-Kit, and more selective for VEGFR.</p>Formula:C25H27FN4O3Purity:97.21% - 99.94%Color and Shape:SolidMolecular weight:450.51SCR-1481B1
CAS:<p>SCR-1481B1 (c-Met inhibitor 2) has activity against cancers dependent on Met activation and also has activity against cancers as a VEGFR inhibitor</p>Formula:C32H40ClF2N6O13PPurity:98.07%Color and Shape:SolidMolecular weight:821.12Oglufanide
CAS:<p>Oglufanide (H-Glu-Trp-OH) is a naturally occurring thymic immunomodulator,and inhibits vascular endothelial growth factor (VEGF).</p>Formula:C16H19N3O5Purity:99.80%Color and Shape:SolidMolecular weight:333.34EOC317
CAS:<p>EOC317 (ACTB-1003) is an oral kinase inhibitor (IC50: 6/2/4 nM, for FGFR1/VEGFR2/Tie-2).</p>Formula:C27H26F5N7O3Purity:98.00% - 99.26%Color and Shape:SolidMolecular weight:591.53SU5208
CAS:<p>SU5208 (3-[(Thien-2-yl)methylene]-2-indolinone) is a compound with bioactivity.SU5208 inhibits vascular endothelial growth factor receptor-2 (VEGFR2).</p>Formula:C13H9NOSPurity:99.62%Color and Shape:SolidMolecular weight:227.28Linifanib
CAS:<p>Linifanib (AL-39324) (ABT-869) is a novel, potent ATP-competitive VEGFR/PDGFR inhibitor for KDR (IC50: 4 nM), CSF-1R (IC50: 3 nM), Flt-1/3 (IC50: 3/4 nM) and</p>Formula:C21H18FN5OPurity:98% - 98.24%Color and Shape:SolidMolecular weight:375.4GW786034B
CAS:<p>Pazopanib HCl (Votrient) inhibits VEGFR1-3, PDGFR, FGFR, c-Kit, c-Fms with IC50 range 10-146 nM in cell-free assays.</p>Formula:C21H23N7O2S·HClPurity:99.87%Color and Shape:SolidMolecular weight:473.98KI8751
CAS:<p>KI8751 is a potent and selective inhibitor of VEGFR2 with IC50 of 0.9 nM.</p>Formula:C24H18F3N3O4Purity:99.22% - 99.9%Color and Shape:SolidMolecular weight:469.41Vatalanib dihydrochloride
CAS:<p>Vatalanib dihydrochloride (PTK787 dihydrochloride)(IC50=37 nM) is an inhibitor of VEGFR2/KDR.</p>Formula:C20H15ClN4·2HClPurity:99.16%Color and Shape:White To Off-White Crystalline PowderMolecular weight:419.73CYC-116
CAS:<p>CYC116 is a potent inhibitor of Aurora A/B with Ki of 8.0 nM/9.2 nM, is less potent to VEGFR2 (Ki of 44 nM), with 50-fold greater potency than CDKs, not active</p>Formula:C18H20N6OSPurity:97.36% - 97.59%Color and Shape:SolidMolecular weight:368.46Golvatinib
CAS:<p>Golvatinib (E-7050) is an orally bioavailable dual kinase inhibitor of c-Met (hepatocyte growth factor receptor) and VEGFR-2 (vascular endothelial growth factor</p>Formula:C33H37F2N7O4Purity:98.24% - ≥95%Color and Shape:SolidMolecular weight:633.69Ningetinib Tosylate
CAS:<p>Ningetinib Tosylate is an orally bioavailable tyrosine kinase inhibitor with IC50s of <1.0, 1.9 and 6.7 nM for Axl, VEGFR2, and c-Met, respectively.</p>Formula:C38H37FN4O8SPurity:99.93%Color and Shape:SolidMolecular weight:728.79Ponatinib
CAS:<p>Ponatinib (AP24534) is an orally available, multitargeted kinase inhibitor (IC50s: 0.37/1.1/1.5/2.2/5.4 nM for Abl, PDGFRα, VEGFR2, FGFR1, and Src, respectively</p>Formula:C29H27F3N6OPurity:98% - 99.60%Color and Shape:SolidMolecular weight:532.56
