VEGFR
VEGFR (Vascular Endothelial Growth Factor Receptor) inhibitors are compounds that block the signaling of VEGFR, a key receptor in the VEGF pathway, which is crucial for angiogenesis. VEGFR inhibitors prevent the formation of new blood vessels that supply nutrients and oxygen to tumors, thereby inhibiting tumor growth. These inhibitors are widely used in cancer therapy and research to study the mechanisms of angiogenesis and develop anti-cancer treatments. At CymitQuimica, we provide a comprehensive range of high-quality VEGFR inhibitors to support your research in oncology, vascular biology, and angiogenesis.
Found 239 products of "VEGFR"
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Ripretinib
CAS:Ripretinib (DCC-2618) is an orally bioavailable inhibitor of KIT and PDGFRA.Formula:C24H21BrFN5O2Purity:99.07% - 99.62%Color and Shape:SolidMolecular weight:510.36Ref: TM-T8482
1mg74.00€2mg97.00€5mg165.00€10mg274.00€25mg432.00€50mg692.00€100mg1,121.00€200mg1,539.00€1mL*10mM (DMSO)202.00€XL092
CAS:XL092 (JUN04542) is an Axl Mer cMet KDR inhibitor for the treatment of Axl and Mer receptor tyrosine kinase- dependent disorders.
Formula:C29H25FN4O5Purity:98.60%Color and Shape:SolidMolecular weight:528.53(Z)-Guggulsterone
CAS:(Z)-Guggulsterone triggers apoptosis in prostate cancer cells and blocks angiogenesis by inhibiting VEGF pathways.Formula:C21H28O2Purity:98.93% - 99.72%Color and Shape:SolidMolecular weight:312.45Tanshinone IIA
CAS:Tanshinone IIA (Tanshinone B) is a natural diterpene quinone. Tanshinone IIA has anti-inflammatory, antioxidant activities. Cost-effective and quality-assured.Formula:C19H18O3Purity:99.04% - >99.99%Color and Shape:Cherry CrystalMolecular weight:294.34Dovitinib lactate hydrate
CAS:Dovitinib lactate hydrate (TKI258) is the Lactate of Dovitinib, which is a multitargeted RTK inhibitor, mostly for class III (FLT3/c-Kit).Formula:C24H27FN6O4Purity:99.82%Color and Shape:SolidMolecular weight:482.51Takeda-6d
CAS:Takeda-6d is a novel, potent DFG-out RAF/vascular endothelial growth factor receptor 2 (VEGFR2) inhibitor with IC50 of 7.0 nM and 2.2 nM, respectively.Formula:C27H19ClFN5O3SPurity:98.27%Color and Shape:SolidMolecular weight:547.99Ref: TM-T22436
1mg92.00€2mg128.00€5mg178.00€10mg268.00€25mg439.00€50mg610.00€100mg820.00€200mg1,099.00€1mL*10mM (DMSO)243.00€Vandetanib
CAS:Vandetanib (ZD6474) is a potent inhibitor of VEGFR2 (IC50: 40 nM). It also inhibits VEGFR3 and EGFR.Formula:C22H24BrFN4O2Purity:99.7% - >99.99%Color and Shape:White SolidMolecular weight:475.35Ref: TM-T1656
10mg50.00€25mg65.00€50mg92.00€100mg166.00€200mg224.00€500mg359.00€1mL*10mM (DMSO)52.00€PD173074
CAS:PD173074 inhibits FGFR1 (IC50: 25 nM) and VEGFR2 (100-200 nM); ~1000x more selective for FGFR1 over PDGFR/c-Src.Formula:C28H41N7O3Purity:98.15% - 98.21%Color and Shape:Yellow SolidMolecular weight:523.67Ref: TM-T2642
5mg40.00€10mg54.00€25mg94.00€50mg133.00€100mg210.00€200mg371.00€500mg620.00€1mL*10mM (DMSO)56.00€TAK-593
CAS:TAK-593 is an effective VEGFR and PDGFR family inhibitor (IC50s: 3.2, 0.95, 1.1, 4.3, and 13 nM for VEGFR1, VEGFR2, VEGFR3, PDFGRα, and PDFGRβ, respectively).Formula:C23H23N7O3Purity:99.37%Color and Shape:SolidMolecular weight:445.47Ref: TM-T16975
2mg42.00€5mg62.00€10mg96.00€25mg182.00€50mg284.00€100mg409.00€200mg575.00€1mL*10mM (DMSO)73.00€Bevacizumab
CAS:Ipilimumab targets CTLA-4, an immune checkpoint inhibitor. Bevacizumab binds to VEGF-A isoforms.Purity:95.40% - CE-SDS:97.5% SEC-HPLC:98.0%Color and Shape:LiquidMolecular weight:146.53 kDaRef: TM-T9904
1mg127.00€2mg202.00€5mg376.00€10mg560.00€25mg895.00€50mg1,216.00€100mg1,634.00€200mg2,213.00€Isolinderalactone
CAS:Isolinderalactone shows anti-inflammatory and anticancer capacity, and it exhibits moderate iNOS inhibitory activity, with the IC50 value of 0.30 uM.Formula:C15H16O3Purity:98.76%Color and Shape:SolidMolecular weight:244.29PP121
CAS:PP-121 inhibits PDGFR, Hck, mTOR, VEGFR2, Src, Abl, and DNA-PK with IC50 values ranging from 2 to 60 nM.Formula:C17H17N7Purity:98.45% - 99.93%Color and Shape:SolidMolecular weight:319.36SU4312
CAS:SU-4312 (DMBI) inhibits VEGFR & PDGFR (IC50: 0.8, 19.4 μM) and shields neurons from MPP(+)-induced damage by blocking nNOS.
Formula:C17H16N2OPurity:>99.99%Color and Shape:SolidMolecular weight:264.32Semaxinib
CAS:Semaxinib (SU5416): potent VEGFR2 inhibitor, 20x more selective over PDGFRβ, not active on InsR/EGFR/FGFR, blocks ATP on VEGFR2, may reduce tumor vessels.
Formula:C15H14N2OPurity:99.84%Color and Shape:Yellow To Yellow OrangeMolecular weight:238.28ZM 306416
CAS:ZM 306416 (CB 676475), a VEGFR1 inhibitor (IC50: 0.33 μM), can also inhibit EGFR (IC50<10 nM).
Formula:C16H13ClFN3O2Purity:99.37% - ≥95%Color and Shape:SolidMolecular weight:333.74Vatalanib free base
CAS:Vatalanib is a VEGFR2/KDR inhibitor (IC50: 37 nM).Formula:C20H15ClN4Purity:99.52%Color and Shape:SolidMolecular weight:346.81Sodium taurocholate
CAS:Sodium taurocholate hydrate, a cholesterol breakdown product, cycles from bile to liver, changing forms via microbes and enzymes.Formula:C26H44NO7S·NaPurity:95% - 99.64%Color and Shape:White PowderMolecular weight:537.69Midostaurin
CAS:PKC412(Midostaurin (PKC412); CGP41231; CGP41251) is a broad spectrum protein kinase inhibitor.Formula:C35H30N4O4Purity:97.61% - >99.99%Color and Shape:SolidMolecular weight:570.64Ref: TM-T3211
1mg49.00€5mg84.00€10mg119.00€25mg205.00€50mg310.00€100mg462.00€500mg1,035.00€1mL*10mM (DMSO)90.00€SU14813
CAS:SU14813: inhibits multiple kinases (VEGFR2, VEGFR1, PDGFRβ, KIT) with IC50s of 50, 2, 4, 15 nM; antiangiogenic and antitumor.Formula:C23H27FN4O4Purity:98.13%Color and Shape:SolidMolecular weight:442.48MGCD-265 analog
CAS:Glesatinib, an oral tyrosine kinase inhibitor, targets c-Met and VEGFR2 with IC50s of 29 nM and 10 nM, may treat cancer.Formula:C26H20FN5O2S2Purity:98.06% - 98.68%Color and Shape:SolidMolecular weight:517.6
