VEGFR
VEGFR (Vascular Endothelial Growth Factor Receptor) inhibitors are compounds that block the signaling of VEGFR, a key receptor in the VEGF pathway, which is crucial for angiogenesis. VEGFR inhibitors prevent the formation of new blood vessels that supply nutrients and oxygen to tumors, thereby inhibiting tumor growth. These inhibitors are widely used in cancer therapy and research to study the mechanisms of angiogenesis and develop anti-cancer treatments. At CymitQuimica, we provide a comprehensive range of high-quality VEGFR inhibitors to support your research in oncology, vascular biology, and angiogenesis.
Found 268 products of "VEGFR"
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BMS-794833
CAS:<p>BMS-794833 is a potent ATP competitive inhibitor of Met/VEGFR2; a prodrug of BMS-817378.</p>Formula:C23H15ClF2N4O3Purity:98% - 99.69%Color and Shape:SolidMolecular weight:468.84Gandotinib
CAS:<p>LY2784544(Gandotinib (LY2784544)) is a potent JAK2 inhibitor (IC50: 3 nM), effective in JAK2V617F(Ki: 0.245 nM).</p>Formula:C23H25ClFN7OPurity:99.33% - 99.86%Color and Shape:SolidMolecular weight:469.94ZD-4190
CAS:<p>ZD-4190 blocks VEGFR2 and EGFR, aiding cancer treatment.</p>Formula:C19H16BrFN6O2Purity:99.12%Color and Shape:SolidMolecular weight:459.27SKLB1002
CAS:<p>SKLB1002 is a potent and ATP-competitive VEGFR2 inhibitor with IC50 of 32 nM.</p>Formula:C13H12N4O2S2Purity:98.51% - >99.99%Color and Shape:SolidMolecular weight:320.39Lenvatinib mesylate
CAS:<p>Lenvatinib mesylate (E7080 (mesylate)) is an oral and multi-targeted inhibitor of VEGFR1-3, FGFR1-4, PDGFR, KIT, and RET, with potent antitumor activities.</p>Formula:C22H23ClN4O7SPurity:99.03% - 99.79%Color and Shape:SolidMolecular weight:522.96PF 477736
CAS:<p>PF 477736 (PF-736,PF-00477736) is a specifc, effective and ATP-competitive Chk1 inhibitor (Ki: 0.49 nM ) and also inhibits FGFR3, Aurora-A, VEGFR2, Flt3, Fms (</p>Formula:C22H25N7O2Purity:97.58% - 99.94%Color and Shape:SolidMolecular weight:419.48OSI-930
CAS:<p>OSI-930 is an oral c-Kit/VEGFR-2 inhibitor targeting tumor growth and angiogenesis.</p>Formula:C22H16F3N3O2SPurity:99.67%Color and Shape:SolidMolecular weight:443.44Regorafenib monohydrate
CAS:<p>Regorafenib Monohydrate is a novel oral multikinase inhibitor with IC50 values of 13, 4.2, 46, 22, 7, 1.5, 2.5, 28, 19 nM for VEGFR1, murine VEGFR2, murine</p>Formula:C21H17ClF4N4O4Purity:99.69%Color and Shape:SolidMolecular weight:500.83VEGFR2-IN-2
CAS:<p>VEGFR2-IN-2 has anti-inflammatory and analgesic activities.</p>Formula:C15H11BrN2OPurity:99.504%Color and Shape:SolidMolecular weight:315.16Ripretinib
CAS:<p>Ripretinib (DCC-2618) is an orally bioavailable inhibitor of KIT and PDGFRA.</p>Formula:C24H21BrFN5O2Purity:99.07% - 99.38%Color and Shape:SolidMolecular weight:510.36XL092
CAS:<p>XL092 (JUN04542) is an Axl Mer cMet KDR inhibitor for the treatment of Axl and Mer receptor tyrosine kinase- dependent disorders.</p>Formula:C29H25FN4O5Purity:98.60%Color and Shape:SolidMolecular weight:528.53TAK-659 hydrochloride
CAS:<p>TAK-659 hydrochloride (TAK-659) is a potent and selective inhibitor of spleen tyrosine kinase (SYK) with an IC50 value of 3.2 nM.</p>Formula:C17H22ClFN6OPurity:99.28% - 99.82%Color and Shape:SolidMolecular weight:380.85CP-673451
CAS:<p>CP-673451 is a specific inhibitor of PDGFRα/β (IC50: 10/1 nM) with antiangiogenic and antitumor activity and the selectivity is higher 450-fold than other</p>Formula:C24H27N5O2Purity:99.62% - 99.88%Color and Shape:SolidMolecular weight:417.5(Z)-Guggulsterone
CAS:<p>(Z)-Guggulsterone triggers apoptosis in prostate cancer cells and blocks angiogenesis by inhibiting VEGF pathways.</p>Formula:C21H28O2Purity:98.93% - 99.72%Color and Shape:SolidMolecular weight:312.45Tanshinone IIA
CAS:<p>Tanshinone IIA (Tanshinone B) is a natural diterpene quinone. Tanshinone IIA has anti-inflammatory, antioxidant activities. Cost-effective and quality-assured.</p>Formula:C19H18O3Purity:99.04% - >99.99%Color and Shape:Cherry CrystalMolecular weight:294.34Dovitinib lactate hydrate
CAS:<p>Dovitinib lactate hydrate (TKI258) is the Lactate of Dovitinib, which is a multitargeted RTK inhibitor, mostly for class III (FLT3/c-Kit).</p>Formula:C24H27FN6O4Purity:99.82%Color and Shape:SolidMolecular weight:482.51Takeda-6d
CAS:<p>Takeda-6d is a novel, potent DFG-out RAF/vascular endothelial growth factor receptor 2 (VEGFR2) inhibitor with IC50 of 7.0 nM and 2.2 nM, respectively.</p>Formula:C27H19ClFN5O3SPurity:98.27%Color and Shape:SolidMolecular weight:547.99AZD4547
CAS:<p>AZD4547 is an FGFR family inhibitor, and is able to act on FGFR1, FGFR2, FGFR3 and FGFR4. IC50:165 nM).Cost-effective and quality-assured.</p>Formula:C26H33N5O3Purity:99.37% - 99.88%Color and Shape:SolidMolecular weight:463.57Vandetanib
CAS:<p>Vandetanib (ZD6474) is a potent inhibitor of VEGFR2 (IC50: 40 nM). It also inhibits VEGFR3 and EGFR.</p>Formula:C22H24BrFN4O2Purity:99.7% - >99.99%Color and Shape:White SolidMolecular weight:475.35PD173074
CAS:<p>PD173074 inhibits FGFR1 (IC50: 25 nM) and VEGFR2 (100-200 nM); ~1000x more selective for FGFR1 over PDGFR/c-Src.</p>Formula:C28H41N7O3Purity:98.15% - 98.21%Color and Shape:Yellow SolidMolecular weight:523.67
