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VEGFR

VEGFR

VEGFR (Vascular Endothelial Growth Factor Receptor) inhibitors are compounds that block the signaling of VEGFR, a key receptor in the VEGF pathway, which is crucial for angiogenesis. VEGFR inhibitors prevent the formation of new blood vessels that supply nutrients and oxygen to tumors, thereby inhibiting tumor growth. These inhibitors are widely used in cancer therapy and research to study the mechanisms of angiogenesis and develop anti-cancer treatments. At CymitQuimica, we provide a comprehensive range of high-quality VEGFR inhibitors to support your research in oncology, vascular biology, and angiogenesis.

Found 268 products of "VEGFR"

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  • Pamufetinib mesylate
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    Pamufetinib mesylate

    CAS:
    <p>Pamufetinib mesylate (TAS-115 mesylate) is a VEGFR antagonist and c-Met inhibitor used in the study of cancer and respiratory diseases.</p>
    Formula:C28H27FN4O7S2
    Purity:98.91%
    Color and Shape:Solid
    Molecular weight:614.67

    Ref: TM-T13108L

  • TAK-593
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    TAK-593

    CAS:
    <p>TAK-593 is an effective VEGFR and PDGFR family inhibitor (IC50s: 3.2, 0.95, 1.1, 4.3, and 13 nM for VEGFR1, VEGFR2, VEGFR3, PDFGRα, and PDFGRβ, respectively).</p>
    Formula:C23H23N7O3
    Purity:99.37%
    Color and Shape:Solid
    Molecular weight:445.47

    Ref: TM-T16975

  • Bevacizumab
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    Bevacizumab

    CAS:
    <p>Ipilimumab targets CTLA-4, an immune checkpoint inhibitor. Bevacizumab binds to VEGF-A isoforms.</p>
    Purity:95.40% - CE-SDS:97.5% SEC-HPLC:98.0%
    Color and Shape:Liquid
    Molecular weight:146.53 kDa

    Ref: TM-T9904

  • Isolinderalactone
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    Isolinderalactone

    CAS:
    <p>Isolinderalactone shows anti-inflammatory and anticancer capacity, and it exhibits moderate iNOS inhibitory activity, with the IC50 value of 0.30 uM.</p>
    Formula:C15H16O3
    Purity:99.62%
    Color and Shape:Solid
    Molecular weight:244.29

    Ref: TM-T8213

  • PP121
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    PP121

    CAS:
    <p>PP-121 inhibits PDGFR, Hck, mTOR, VEGFR2, Src, Abl, and DNA-PK with IC50 values ranging from 2 to 60 nM.</p>
    Formula:C17H17N7
    Purity:98.45% - 99.67%
    Color and Shape:Solid
    Molecular weight:319.36

    Ref: TM-T2415

  • SU4312
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    SU4312

    CAS:
    <p>SU-4312 (DMBI) inhibits VEGFR &amp; PDGFR (IC50: 0.8, 19.4 μM) and shields neurons from MPP(+)-induced damage by blocking nNOS.</p>
    Formula:C17H16N2O
    Purity:>99.99%
    Color and Shape:Solid
    Molecular weight:264.32

    Ref: TM-T3570

  • Semaxinib
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    Semaxinib

    CAS:
    <p>Semaxinib (SU5416): potent VEGFR2 inhibitor, 20x more selective over PDGFRβ, not active on InsR/EGFR/FGFR, blocks ATP on VEGFR2, may reduce tumor vessels.</p>
    Formula:C15H14N2O
    Purity:99.84%
    Color and Shape:Yellow To Yellow Orange
    Molecular weight:238.28

    Ref: TM-T2064

  • ZM 306416
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    ZM 306416

    CAS:
    <p>ZM 306416 (CB 676475), a VEGFR1 inhibitor (IC50: 0.33 μM), can also inhibit EGFR (IC50&lt;10 nM).</p>
    Formula:C16H13ClFN3O2
    Purity:99.37% - ≥95%
    Color and Shape:Solid
    Molecular weight:333.74

    Ref: TM-T1754

  • Vatalanib free base
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    Vatalanib free base

    CAS:
    <p>Vatalanib is a VEGFR2/KDR inhibitor (IC50: 37 nM).</p>
    Formula:C20H15ClN4
    Purity:99.52%
    Color and Shape:Solid
    Molecular weight:346.81

    Ref: TM-T17219

  • Sodium taurocholate
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    Sodium taurocholate

    CAS:
    <p>Sodium taurocholate hydrate, a cholesterol breakdown product, cycles from bile to liver, changing forms via microbes and enzymes.</p>
    Formula:C26H44NO7S·Na
    Purity:95% - 99.64%
    Color and Shape:White Powder
    Molecular weight:537.69

    Ref: TM-TWA2417

  • Midostaurin
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    Midostaurin

    CAS:
    <p>PKC412(Midostaurin (PKC412); CGP41231; CGP41251) is a broad spectrum protein kinase inhibitor.</p>
    Formula:C35H30N4O4
    Purity:97.61% - >99.99%
    Color and Shape:Solid
    Molecular weight:570.64

    Ref: TM-T3211

  • SU14813
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    SU14813

    CAS:
    <p>SU14813: inhibits multiple kinases (VEGFR2, VEGFR1, PDGFRβ, KIT) with IC50s of 50, 2, 4, 15 nM; antiangiogenic and antitumor.</p>
    Formula:C23H27FN4O4
    Purity:98.13%
    Color and Shape:Solid
    Molecular weight:442.48

    Ref: TM-T7945

  • MGCD-265 analog
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    MGCD-265 analog

    CAS:
    <p>Glesatinib, an oral tyrosine kinase inhibitor, targets c-Met and VEGFR2 with IC50s of 29 nM and 10 nM, may treat cancer.</p>
    Formula:C26H20FN5O2S2
    Purity:98.06% - 98.68%
    Color and Shape:Solid
    Molecular weight:517.6

    Ref: TM-T6351

  • R1530
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    R1530

    CAS:
    <p>R1530 is a multikinase inhibitor with antineoplastic and antiangiogenesis activities.</p>
    Formula:C18H14ClFN4O
    Purity:98.422%
    Color and Shape:Solid
    Molecular weight:356.78

    Ref: TM-TQ0317

  • Ribociclib
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    Ribociclib

    CAS:
    <p>Ribociclib (LEE011) is an orally available, and highly specific CDK4/6 inhibitor (IC50：10/39 nM).</p>
    Formula:C23H30N8O
    Purity:97.91% - >99.99%
    Color and Shape:Solid
    Molecular weight:434.54

    Ref: TM-T6199

  • SAR131675
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    SAR131675

    CAS:
    <p>SAR131675 is a potent and selective VEGFR3 inhibitor with an IC50 of 23 nM.</p>
    Formula:C18H22N4O4
    Purity:99.74%
    Color and Shape:Solid
    Molecular weight:358.39

    Ref: TM-T6012

  • Nintedanib esylate
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    Nintedanib esylate

    CAS:
    <p>Nintedanib esylate (BIBF 1120 esylate) is a potent triple angiokinase inhibitor for VEGFR1/2/3, FGFR1/2/3 and PDGFRα/β</p>
    Formula:C31H33N5O4·C2H6O3S
    Purity:99.43% - 99.96%
    Color and Shape:Solid
    Molecular weight:649.76

    Ref: TM-T5001

  • Ki20227
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    Ki20227

    CAS:
    <p>Ki-20227 is a specific c-Fms tyrosine kinase(CSF1R) inhibitor (IC50: 2 nM).</p>
    Formula:C24H24N4O5S
    Purity:98.97% - 99.88%
    Color and Shape:Solid
    Molecular weight:480.54

    Ref: TM-T4315

  • Tyrphostin A9
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    Tyrphostin A9

    CAS:
    <p>Tyrphostin A9 (SF 6847) is an Agricultural acaricide, now superseded. Tyrphostin A9 is firstly designed as an EGFR inhibitor</p>
    Formula:C18H22N2O
    Purity:98.21% - 99.87%
    Color and Shape:Yellow Solid
    Molecular weight:282.38

    Ref: TM-T2479

  • LY2874455
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    LY2874455

    CAS:
    <p>LY2874455 has been used in trials studying the treatment of Advanced Cancer.</p>
    Formula:C21H19Cl2N5O2
    Purity:97.22% - 99.46%
    Color and Shape:Solid
    Molecular weight:444.31

    Ref: TM-T2361