VEGFR
VEGFR (Vascular Endothelial Growth Factor Receptor) inhibitors are compounds that block the signaling of VEGFR, a key receptor in the VEGF pathway, which is crucial for angiogenesis. VEGFR inhibitors prevent the formation of new blood vessels that supply nutrients and oxygen to tumors, thereby inhibiting tumor growth. These inhibitors are widely used in cancer therapy and research to study the mechanisms of angiogenesis and develop anti-cancer treatments. At CymitQuimica, we provide a comprehensive range of high-quality VEGFR inhibitors to support your research in oncology, vascular biology, and angiogenesis.
Found 256 products for "VEGFR".
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Tivozanib
CAS:Tivozanib (KRN951) is an oral VEGFRs 1-3 inhibitor with potential antiangiogenic and cancer-fighting properties.Formula:C22H19ClN4O5Purity:98.08% - 99.67%Color and Shape:SolidMolecular weight:454.86Ref: TM-T2456
2mg38.00€5mg57.00€1mL*10mM (DMSO)63.00€10mg79.00€25mg135.00€50mg226.00€100mg405.00€200mg597.00€MAZ51
CAS:MAZ51 is a VEGFR-3 (Flt-4) tyrosine kinase inhibitor.Formula:C21H18N2OPurity:98.53% - 99.90%Color and Shape:Red SolidMolecular weight:314.38AZD2932
CAS:AZD2932 is a potent and multi-targeted kinase inhibitor VEGFR2, PDGFβ, Flt-3, and c-Kit.Formula:C24H25N5O4Purity:97.71% - 98.37%Color and Shape:SolidMolecular weight:447.49(Z)-Guggulsterone
CAS:(Z)-Guggulsterone triggers apoptosis in prostate cancer cells and blocks angiogenesis by inhibiting VEGF pathways.Formula:C21H28O2Purity:98.93% - 99.72%Color and Shape:SolidMolecular weight:312.45AMG-47a
CAS:AMG-47a inhibits Lck, T cell growth, and degrades KRAS oncoprotein, affecting EGFP-KRASG12V but not EGFP.Formula:C29H28F3N5O2Purity:98%Color and Shape:SolidMolecular weight:535.56Xanthatin
CAS:Xanthatin exhibits cytotoxic, antibacterial, antifungal properties, may treat NSCLC, and inhibits melanoma by targeting Wnt/β-catenin and angiogenesis.Formula:C15H18O3Purity:98.48% - 99.96%Color and Shape:White SolidMolecular weight:246.3Dovitinib lactate
CAS:Dovitinib lactate (TKI-258 lactate)(TKI258) lactate is a potent inhibitor of fibroblast growth factor receptor 3 (FGFR3) (IC50 :5 nM).Formula:C24H27FN6O4Purity:99.54% - 99.77%Color and Shape:SolidMolecular weight:482.51Ref: TM-T7104
5mg49.00€1mL*10mM (DMSO)54.00€10mg74.00€25mg122.00€50mg202.00€100mg339.00€200mg507.00€500mg800.00€AAL-993
CAS:AAL-993: VEGFR inhibitor; IC50: 130 nM (1), 23 nM (2), 18 nM (3); weak on other tyrosine kinases; antiangiogenic & antitumor.Formula:C20H16F3N3OPurity:99.65%Color and Shape:SolidMolecular weight:371.36Ref: TM-T21593
1mg43.00€1mL*10mM (DMSO)92.00€5mg93.00€10mg138.00€25mg260.00€50mg409.00€100mg605.00€500mg1,288.00€RAF265
CAS:RAF265 (CHIR-265) inhibits C-Raf/B-Raf/V600E (IC50: 3-60 nM), blocks VEGFR2 (EC50: 30 nM), in Phase 2 trials.Formula:C24H16F6N6OPurity:99.56%Color and Shape:White SolidMolecular weight:518.41Ref: TM-T6296
1mg44.00€2mg59.00€5mg93.00€1mL*10mM (DMSO)94.00€10mg140.00€25mg253.00€50mg413.00€100mg605.00€NVP-BAW2881
CAS:NVP-BAW2881 (BAW2881) is a potent and selective VEGFR inhibitor with activity to inhibit chronic and acute skin inflammation.Formula:C22H15F3N4O2Purity:98.19% - 99.97%Color and Shape:White SolidMolecular weight:424.38Ref: TM-T3641
1mg34.00€2mg48.00€1mL*10mM (DMSO)69.00€5mg71.00€10mg109.00€25mg200.00€50mg324.00€100mg470.00€500mg1,054.00€SU5205
CAS:SU5205 is a VEGFR2 inhibitor.Formula:C15H10FNOPurity:99.62% - 99.67%Color and Shape:White SolidMolecular weight:239.24Foretinib
CAS:Foretinib (GSK1363089) is a broad-spectrum tyrosine kinase inhibitor with IC50s of 0.4 nM and 0.9 nM for Met and KDR.Formula:C34H34F2N4O6Purity:98.07% - 99.68%Color and Shape:SolidMolecular weight:632.65Ref: TM-T3113
2mg37.00€5mg54.00€10mg74.00€1mL*10mM (DMSO)74.00€25mg126.00€50mg195.00€100mg335.00€500mg803.00€Vorolanib
CAS:Vorolanib (X-82) is an orally active VEGFR/PDGFR dual inhibitor.Formula:C23H26FN5O3Purity:97.35%Color and Shape:SolidMolecular weight:439.48Ref: TM-T8491
1mg101.00€2mg142.00€5mg215.00€1mL*10mM (DMSO)236.00€10mg340.00€25mg583.00€50mg842.00€100mg1,144.00€200mg1,521.00€Fruquintinib
CAS:Fruquintinib (HMPL-013) is an orally available, small molecule inhibitor of vascular endothelial growth factor receptors (VEGFRs), with potential anti-Formula:C21H19N3O5Purity:98.84% - 99.89%Color and Shape:SolidMolecular weight:393.39Ref: TM-T2656
2mg34.00€5mg50.00€1mL*10mM (DMSO)55.00€10mg80.00€25mg111.00€50mg140.00€100mg236.00€500mg587.00€Orantinib
CAS:Orantinib (NSC 702827) , a excellent effective against PDGFR autophosphorylation with Ki of 8 nM, also highly inhibits Flk-1 and FGFR1 trans-phosphorylation.Formula:C18H18N2O3Purity:98.92% - 99.52%Color and Shape:Yellow SolidMolecular weight:310.35AG-13958
CAS:AG-13958 (AG-013958) (AG-013958), a potent VEGFR tyrosine kinase inhibitor, for the treatment of age-related macular degeneration.Formula:C26H22FN7OPurity:99.4% - 99.68%Color and Shape:SolidMolecular weight:467.5Ref: TM-T7493
1mg92.00€5mg250.00€1mL*10mM (DMSO)260.00€10mg385.00€25mg620.00€50mg893.00€100mg1,189.00€Motesanib
CAS:Motesanib (AMG 706) orally blocks VEGFR, PDGFR, Kit, Ret; curbing angiogenesis and cancer cell growth.Formula:C22H23N5OPurity:98% - 99.09%Color and Shape:Yellow SolidMolecular weight:373.45Ref: TM-T2288
5mg34.00€1mL*10mM (DMSO)39.00€10mg49.00€25mg81.00€50mg114.00€100mg160.00€200mg230.00€500mg389.00€KRN-633
CAS:KRN-633 is an effective VEGFR inhibitor. The IC50s of KRN-633(KRN633) for VEGFR1, VEGFR2, and VEGFR3 is 170, 160 and 125 nM, respectively.Formula:C20H21ClN4O4Purity:99.53% - 99.73%Color and Shape:SolidMolecular weight:416.86JI-101
CAS:JI-101 (CGI-1842) is an oral multi-kinase inhibitor that targets VEGFR-2, PDGFR-β, and EphB4.Formula:C22H20BrN5O2Purity:99.41% - 99.97%Color and Shape:SolidMolecular weight:466.33Ilorasertib
CAS:Ilorasertib (ABT-348) inhibits Aurora kinases A/B/C & RET, PDGFRβ, Flt1 (IC50: 1-120 nM).Formula:C25H21FN6O2SPurity:96.17% - 97.49%Color and Shape:Yellow SolidMolecular weight:488.54
