TAM Receptor
TAM receptor inhibitors target the TAM family of receptor tyrosine kinases, which includes Tyro3, Axl, and Mer. These receptors are involved in the regulation of immune responses, cell survival, and clearance of apoptotic cells. Dysregulation of TAM receptors is implicated in cancer, autoimmune diseases, and chronic inflammation. At CymitQuimica, we offer TAM receptor inhibitors to aid your research in immunology, oncology, and inflammation.
Found 32 products of "TAM Receptor"
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TAM-IN-2
CAS:<p>TAM-IN-2 is an inhibitor of TAM.</p>Formula:C31H27F2N7O3Purity:98.09% - 99.74%Color and Shape:SolidMolecular weight:583.59Tilvestamab
CAS:<p>Tilvestamab (BGB149) is a humanized monoclonal antibody targeting AXL with anti-tumor and anti-fibrotic activities, inhibiting Gas6-induced AXL activation.</p>Purity:>95%Color and Shape:LiquidEnapotamab vedotin
CAS:<p>Enapotamab vedotin (anti-AXL ADC) targets AXL with MMAE payload, showing potential against AXL-expressing, EGFR-resistant NSCLC.</p>Purity:95%Color and Shape:LiquidMecbotamab vedotin
CAS:<p>Mecbotamab vedotin (BA301) is an inhibitory IgG1 antibody that targets human tyrosine kinase receptor AXL and the humanized murine monoclonal BA301 γ1 chain. It can be utilized in the preparation of immunoconjugates for research into cancers expressing the Axl type.</p>Color and Shape:LiquidUNC 569 hydrochloride
<p>UNC 569 hydrochloride: reversible ATP-competitive Mer inhibitor, IC50 2.9 nM, Ki 4.3 nM, also inhibits Axl/Tyro3; used in leukemia, teratoid tumor studies.</p>Formula:C22H30ClFN6Purity:99.93%Color and Shape:SolidMolecular weight:432.96UNC2541
CAS:<p>UNC2541 is a potent and Mer tyrosine kinase (MerTK)-specific inhibitor.</p>Formula:C24H34FN7O2Purity:98.33%Color and Shape:SolidMolecular weight:471.572-D08
CAS:<p>2-D08 is a synthetic flavone that inhibits sumoylation, also inhibits Axl with an IC50 of 0.49 nM.2-D08 showed anti-aggregatory and neuroprotective effect.</p>Formula:C15H10O5Purity:98.58% - 98.95%Color and Shape:SolidMolecular weight:270.24Bemcentinib
CAS:<p>Bemcentinib (R428) is a selective inhibitor of Axl (IC50: 14 nM) and has been investigated for the treatment of NSCLC.</p>Formula:C30H34N8Purity:97% - 99.8%Color and Shape:SolidMolecular weight:506.64RU-301
CAS:<p>RU-301 is a novel pan-tam inhibitor</p>Formula:C21H19F3N4O4SPurity:98.87%Color and Shape:SolidMolecular weight:480.46UNC569
CAS:<p>UNC569 selectively inhibits kidney URAT1, regulating uric acid excretion and aiding gout patient's uric balance.</p>Formula:C22H29FN6Purity:98.91% - 99.67%Color and Shape:SolidMolecular weight:396.5BMS 777607
CAS:<p>BMS 777607 (BMS 817378) is a Met-related inhibitor for c-Met/Axl/Ron/Tyro3. BMS-777607 has been investigated for the basic science of Malignant Solid Tumour.</p>Formula:C25H19ClF2N4O4Purity:98.30% - >99.99%Color and Shape:SolidMolecular weight:512.89CEP-40783
CAS:<p>CEP-40783 (RXDX-106) is an effective, specific and orally active AXL/c-Met inhibitor (IC50: 7/12 nM). It also inhibits MER and TYRO3 (IC50: 29/19 nM).</p>Formula:C31H26F2N4O6Purity:99.76% - 99.84%Color and Shape:SolidMolecular weight:588.56Ningetinib Tosylate
CAS:<p>Ningetinib Tosylate is an orally bioavailable tyrosine kinase inhibitor with IC50s of <1.0, 1.9 and 6.7 nM for Axl, VEGFR2, and c-Met, respectively.</p>Formula:C38H37FN4O8SPurity:99.93%Color and Shape:SolidMolecular weight:728.79NPS-1034
CAS:<p>NPS-1034 is a dual Met/Axl inhibitor with IC50 of 48 nM and 10.3 nM, respectively.</p>Formula:C31H23F2N5O3Purity:98.48%Color and Shape:SolidMolecular weight:551.54Gilteritinib
CAS:<p>Gilteritinib (ASP2215) is a potent inhibitor at the FMS-related tyrosine kinase 3 (FLT3) and AXL tyrosine kinase receptors (IC50 = 0.29 nM and <1 nM,</p>Formula:C29H44N8O3Purity:97.75% - 99.90%Color and Shape:SolidMolecular weight:552.71UNC2881
CAS:<p>UNC2881 is a specific Mer tyrosine kinase inhibitor (IC50: 4.3 nM). It is about 83- and 58-fold higher selectivity than Axl and Tyro3, respectively.</p>Formula:C25H33N7O2Purity:98.97% - 99.85%Color and Shape:SolidMolecular weight:463.58SGI-7079
CAS:<p>SGI-7079: selective Axl inhibitor; hinders tumor growth dose-dependently; may target EGFR inhibitor resistance.</p>Formula:C26H26FN7Purity:95.51% - 99.26%Color and Shape:SolidMolecular weight:455.53LDC1267
CAS:<p>LDC1267 is a excellently specific TAM(Tyro3, Axl and Mer) kinase inhibitor, for Mer( IC50<5 nM), Tyro3(IC50=8 nM), and Axl(IC50=29 nM).</p>Formula:C30H26F2N4O5Purity:99.38% - 99.88%Color and Shape:SolidMolecular weight:560.55Ningetinib
CAS:<p>Ningetinib (CT-053) (CT053PTSA) is an orally bioavailable tyrosine kinase inhibitor with IC50s of <1.0, 1.9 and 6.7 nM for Axl, VEGFR2, and c-Met, respectively.</p>Formula:C31H29FN4O5Purity:99.95% - 99.98%Color and Shape:SolidMolecular weight:556.58ONO-7475
CAS:<p>ONO-7475 is an inhibitor with high specificity for anexelekto and MER tyrosine kinase</p>Formula:C32H26N4O6Purity:98.74%Color and Shape:SolidMolecular weight:562.57
