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FLT
Pexidartinib
CAS:1029044-16-3
Pexidartinib is a capsule formulation containing a small-molecule receptor tyrosine kinase (RTK) inhibitor of KIT, …
Formula:
C20H15ClF3N5
Purity:
98.00%
Color and Shape:
solid
Molecular weight:
417.81
Estimated delivery in United States, on Monday 7 Feb 2022
AZD2932
CAS:883986-34-3
AZD2932 is a potent and multi-targeted kinase inhibitor VEGFR2, PDGF, Flt-3, and c-Kit.
Formula:
C24H25N5O4
Purity:
97.71%
Color and Shape:
solid
Molecular weight:
447.49
Estimated delivery in United States, on Monday 7 Feb 2022
Tandutinib
CAS:387867-13-2
Tandutinib (MLN518, CT53518), an effective FLT3 antagonist (IC50: 0.22 μM), can also inhibit c-Kit and …
Formula:
C31H42N6O4
Purity:
99.74%
Color and Shape:
White Solid
Molecular weight:
562.7
Estimated delivery in United States, on Monday 7 Feb 2022
UNC2025 2HCl (1429881-91-3(free base))
UNC2025 is a potent and orally bioavailable Mer/Flt3 dual inhibitor with IC50 of 0.8/0.74 nM …
Formula:
C28H42Cl2N6O
Purity:
98.56%
Color and Shape:
solid
Molecular weight:
549.62
Estimated delivery in United States, on Monday 7 Feb 2022
CHIR124
CAS:405168-58-3
CHIR-124 is an effective Chk1 inhibitor (IC50: 0.3 nM). It has 2, 000-fold selectivity against …
Formula:
C23H22ClN5O
Purity:
96.33%
Color and Shape:
solid
Molecular weight:
419.91
Estimated delivery in United States, on Monday 7 Feb 2022
ATH 686
CAS:853299-52-2
ATH 686 is an potent and selective Inhibitor of FLT3.
Formula:
C25H28F3N7O2
Purity:
99.90%
Color and Shape:
solid
Molecular weight:
515.53
Estimated delivery in United States, on Monday 7 Feb 2022
Sunitinib
CAS:557795-19-4
Sunitinib, a multi-targeted RTK inhibitor, is targeting PDGFR and VEGFR2 (Flk-1) with IC50 of 2 …
Formula:
C22H27FN4O2
Purity:
99.67%
Color and Shape:
Yellow Solid
Molecular weight:
398.47
Estimated delivery in United States, on Monday 7 Feb 2022
AST 487
CAS:630124-46-8
AST 487 is a RET kinase inhibitor, inhibiting RET autophosphorylation and activation of downstream effectors. …
Formula:
C26H30F3N7O2
Purity:
99.56%
Color and Shape:
solid
Molecular weight:
529.56
Estimated delivery in United States, on Monday 7 Feb 2022
NCT503
CAS:1916571-90-8
NCT-503 is an inhibitor of 3-phosphoglycerate dehydrogenase (PHGDH), inhibiting serine synthesis from 3-phosphoglycerate in cells.
Formula:
C20H23F3N4S
Purity:
98.91%
Color and Shape:
Solid
Molecular weight:
408.49
Estimated delivery in United States, on Monday 7 Feb 2022
TAK-659 hydrochloride
CAS:1952251-28-3
TAK-659 is a potent and selective inhibitor of spleen tyrosine kinase (SYK) with an IC50 …
Formula:
C17H22ClFN6O
Purity:
99.28%
Color and Shape:
Solid
Molecular weight:
380.85
Estimated delivery in United States, on Monday 7 Feb 2022
Jasplakinolide
CAS:102396-24-7
Jasplakinolide binds to F-actin competitively with phalloidin with a Kd of 15 nM. Jasplakinolide, a …
Formula:
C36H45BrN4O6
Purity:
98.00%
Color and Shape:
solid
Molecular weight:
709.67
Estimated delivery in United States, on Monday 7 Feb 2022
BPR1J-097 hydrochloride (1327167-19-0(free base))
BPR1J-097, a new-type small molecule FLT-3 inhibitor(IC50=11±7 nM), is with great anti-tumor activities in vivo.
Formula:
C27H29ClN6O3S
Purity:
98.73%
Color and Shape:
solid
Molecular weight:
553.07
Estimated delivery in United States, on Monday 7 Feb 2022
NVP-AEW541
CAS:475489-16-8
NVP-AEW541, a potent inhibitor of IGF-1R(IC50=150 nM) and InsR(IC50=140 nM), exhibits excellent efficiency and specificity …
Formula:
C27H29N5O
Purity:
98.70%
Color and Shape:
solid
Molecular weight:
439.55
Estimated delivery in United States, on Monday 7 Feb 2022
Nintedanib
CAS:656247-17-5
Nintedanib is an inhibitor of the receptor tyrosine kinases VEGFR/FGFR/PDGFR (IC50s: 13-34/37-610/59/65 nM for VEGFR1-3, …
Formula:
C31H33N5O4
Purity:
99.65%
Color and Shape:
solid
Molecular weight:
539.62
Estimated delivery in United States, on Monday 7 Feb 2022
Quizartinib
CAS:950769-58-1
Quizartinib is an inhibitor of FLT3 (Kd: 1.6 nM) and demonstrates high selectivity for FLT3 …
Formula:
C29H32N6O4S
Purity:
98.87%
Color and Shape:
solid
Molecular weight:
560.67
Estimated delivery in United States, on Monday 7 Feb 2022
Amuvatinib
CAS:850879-09-3
Amuvatinib is an orally bioavailable synthetic carbothioamide with potential antineoplastic activity.
Formula:
C23H21N5O3S
Purity:
98.48%
Color and Shape:
solid
Molecular weight:
447.51
Estimated delivery in United States, on Monday 7 Feb 2022
AEE788
CAS:497839-62-0
AEE788 has been used in trials studying the treatment of Cancer, Glioblastoma Multiforme, and Brain …
Formula:
C27H32N6
Purity:
100.00%
Color and Shape:
solid
Molecular weight:
440.58
Estimated delivery in United States, on Monday 7 Feb 2022
5'-Fluoroindirubinoxime
CAS:861214-33-7
5'-Fluoroindirubinoxime is a potent FLT3 inhibitor( IC50 : 15 nM).
Formula:
C16H10FN3O2
Purity:
100.00%
Color and Shape:
solid
Molecular weight:
295.27
Estimated delivery in United States, on Monday 7 Feb 2022
JTV-519 free base
CAS:145903-06-6
JTV-519 free base (K201 free base),Antiarrhythmic and cardioprotective properties. is a Ca2+-dependent blocker of sarcoplasmic …
Formula:
C25H32N2O2S
Purity:
98.00%
Color and Shape:
solid
Molecular weight:
424.6
Estimated delivery in United States, on Monday 7 Feb 2022
FLT3-IN-2
CAS:923562-23-6
FLT3-IN-2 is an FLT3 inhibitor (IC50<1 μM).
Formula:
C21H16ClF3N4
Purity:
98.00%
Color and Shape:
solid
Molecular weight:
416.83
Estimated delivery in United States, on Monday 7 Feb 2022
TCS 359
CAS:301305-73-7
TCS 359 is a potent FLT3 inhibitor with IC50 of 42 nM.
Formula:
C18H20N2O4S
Purity:
99.02%
Color and Shape:
solid
Molecular weight:
360.43
Estimated delivery in United States, on Monday 7 Feb 2022
Sorafenib tosylate
CAS:475207-59-1
Sorafenib is a potent multikinase inhibitor (IC50s: 6/20/22 nM for Raf-1/VEGFR-3/B-Raf).
Formula:
C21H16ClF3N4O3·C7H8O3S
Purity:
99.20%
Color and Shape:
White To Off-White Crystalline Powder
Molecular weight:
637.03
Estimated delivery in United States, on Monday 7 Feb 2022
ENMD2076
CAS:934353-76-1
ENMD-2076, a multi-targeted kinase inhibitor, has specific activity against Aurora A, Flt3, KDR/VEGFR2, Flt4/VEGFR3, FGFR1, …
Formula:
C21H25N7
Purity:
97.63%
Color and Shape:
solid
Molecular weight:
375.47
Estimated delivery in United States, on Monday 7 Feb 2022
Gandotinib
CAS:1229236-86-5
LY2784544(Gandotinib) is a potent JAK2 inhibitor (IC50: 3 nM), effective in JAK2V617F(Ki: 0.245 nM). The …
Formula:
C23H25ClFN7O
Purity:
99.00%
Color and Shape:
solid
Molecular weight:
469.94
Estimated delivery in United States, on Monday 7 Feb 2022
ENMD-2076 L-(+)-Tartaric acid
CAS:1291074-87-7
ENMD-2076 L-(+)-Tartaric acid is the tartaric acid of ENMD-2076, selective activity against Aurora A and …
Formula:
C25H31N7O6
Purity:
98.0%
Molecular weight:
525.56
Estimated delivery in United States, on Monday 7 Feb 2022
MRX-2843
CAS:1429882-07-4
MRX-2843 is a potent and orally active inhibitor of MERTK and FLT3(IC50s of 1.3 nM …
Formula:
C29H40N6O
Purity:
99.51%
Color and Shape:
Solid
Molecular weight:
488.67
Estimated delivery in United States, on Monday 7 Feb 2022
BPR1K871
BPR1K871 is a potent and selective dual FLT3/AURKA inhibitor (IC50s: 22 nM and 19 nM …
Formula:
C25H28ClN7O2S
Purity:
98.00%
Color and Shape:
solid
Molecular weight:
526.05
Estimated delivery in United States, on Monday 7 Feb 2022
CC223
CAS:1228013-30-6
CC-223 is an orally available mTOR inhibitor with potential antitumor activity. CC-223 inhibits the activity …
Formula:
C21H27N5O3
Purity:
99.41%
Color and Shape:
Solid
Molecular weight:
397.47
Estimated delivery in United States, on Monday 7 Feb 2022
UNC2025
CAS:1429881-91-3
UNC-2025 IC50 of 0.74 nM and 0.8 nM is a potent and orally bioavailable dual …
Formula:
C28H40N6O
Purity:
99.74%
Color and Shape:
Solid
Molecular weight:
476.7
Estimated delivery in United States, on Monday 7 Feb 2022
Pacritinib
CAS:937272-79-2
Pacritinib (SB1518) is an effective and specific inhibitor of JAK2 and FLT3 (IC50: 23/22 nM, …
Formula:
C28H32N4O3
Purity:
99.27%
Color and Shape:
solid
Molecular weight:
472.58
Estimated delivery in United States, on Monday 7 Feb 2022
Linifanib
CAS:796967-16-3
Linifanib (ABT-869) is a novel, potent ATP-competitive VEGFR/PDGFR inhibitor for KDR (IC50: 4 nM), CSF-1R …
Formula:
C21H18FN5O
Purity:
98.00%
Color and Shape:
solid
Molecular weight:
375.4
Estimated delivery in United States, on Monday 7 Feb 2022
Brigatinib
CAS:1197953-54-0
Brigatinib is a highly potent and selective ALK inhibitor.
Formula:
C29H39ClN7O2P
Purity:
98.00%
Color and Shape:
solid
Molecular weight:
584.09
Estimated delivery in United States, on Monday 7 Feb 2022
FLT3-IN-3
CAS:2229050-90-0
FLT3-IN-3 is an effective FLT3 inhibitor, and the IC50s of FLT3 WT and FLT3 D835Y …
Formula:
C27H38N8O
Purity:
98.00%
Color and Shape:
Solid
Molecular weight:
490.64
Estimated delivery in United States, on Monday 7 Feb 2022
Gilteritinib
CAS:1254053-43-4
Gilteritinib is a potent inhibitor at the FMS-related tyrosine kinase 3 (FLT3) and AXL tyrosine …
Formula:
C29H44N8O3
Purity:
97.75%
Color and Shape:
solid
Molecular weight:
552.72
Estimated delivery in United States, on Monday 7 Feb 2022
SB1317 hydrochloride (1204918-72-8(free base))
SB1317 is an effective inhibitor of CDK2/JAK2/FLT3 (IC50: 13/73/56 nM).
Formula:
C23H25ClN4O
Purity:
98.11%
Color and Shape:
solid
Molecular weight:
408.92
Estimated delivery in United States, on Monday 7 Feb 2022
AMG 925
CAS:1401033-86-0
AMG 925 is a potent and orally bioavailable dual FLT3/CDK4 inhibitor with IC50 of 1 …
Formula:
C26H29N7O2
Purity:
98.0%
Color and Shape:
solid
Molecular weight:
471.55
Estimated delivery in United States, on Monday 7 Feb 2022
SGI7079
CAS:1239875-86-5
SGI-7079 is a new selective Axl inhibitor. SGI-7079 can be a dose-dependent manner inhibited growth …
Formula:
C26H26FN7
Purity:
99.26%
Color and Shape:
solid
Molecular weight:
455.53
Estimated delivery in United States, on Monday 7 Feb 2022
G749
CAS:1457983-28-6
G-749, a new-type FLT3 inhibitor, exhibits effective and sustained inhibition of the FLT3 wild type …
Formula:
C25H25BrN6O2
Purity:
99.24%
Color and Shape:
solid
Molecular weight:
521.41
Estimated delivery in United States, on Monday 7 Feb 2022
BPR1J097
CAS:1327167-19-0
BPR1J-097 is a novel FLT-3 inhibitor(IC50: 11±7 nM) with promising in vivo anti-tumor activities. It …
Formula:
C27H28N6O3S
Purity:
99.30%
Color and Shape:
solid
Molecular weight:
516.62
Estimated delivery in United States, on Monday 7 Feb 2022
GSK1070916
CAS:942918-07-2
GSK1070916 is a reversible and ATP-competitive inhibitor of Aurora B/C with IC50 of 3.5 nM/6.5 …
Formula:
C30H33N7O
Purity:
98.0%
Molecular weight:
507.63
Estimated delivery in United States, on Monday 7 Feb 2022
TG101209
CAS:936091-14-4
TG101209 is a selective JAK2 inhibitor with IC50 of 6 nM.
Formula:
C26H35N7O2S
Purity:
100.00%
Color and Shape:
solid
Molecular weight:
509.67
Estimated delivery in United States, on Monday 7 Feb 2022
SB1317
CAS:1204918-72-8
SB1317 is a potent inhibitor of cyclin dependant kinases (CDKs), Janus kinase 2 (JAK2), and …
Formula:
C23H24N4O
Molecular weight:
372.46
Estimated delivery in United States, on Monday 7 Feb 2022
FLT3-IN-1
CAS:1370256-78-2
FLT3-IN-1 is a novel potent and selective Flt3 inhibitor.
Formula:
C25H27N7O3S2
Purity:
98.00%
Color and Shape:
solid
Molecular weight:
537.66
Estimated delivery in United States, on Monday 7 Feb 2022
XL019
CAS:945755-56-6
XL019 is a potent and selective JAK2 inhibitor with IC50 of 2.2 nM, 100 fold …
Formula:
C25H28N6O2
Purity:
100.00%
Color and Shape:
solid
Molecular weight:
444.53
Estimated delivery in United States, on Monday 7 Feb 2022
SGI-1776 free base
CAS:1025065-69-3
SGI-1776 has been used in trials studying the treatment of Prostate Cancer, Non-Hodgkins Lymphoma, and …
Formula:
C20H22F3N5O
Purity:
99.30%
Color and Shape:
solid
Molecular weight:
405.42
Estimated delivery in United States, on Monday 7 Feb 2022
OSI 930
CAS:728033-96-3
OSI-930, an orally active inhibitor of c-Kit and the vascular endothelial growth factor receptor-2 (VEGFR-2), …
Formula:
C22H16F3N3O2S
Purity:
98.77%
Color and Shape:
solid
Molecular weight:
443.44
Estimated delivery in United States, on Monday 7 Feb 2022
VX-11e
CAS:896720-20-0
VX-11e is a potent, selective, and orally bioavailable ERK(Extracellular Signal-Regulated Kinase) inhibitor; antitumor agent.
Formula:
C24H20Cl2FN5O2
Purity:
98.00%
Color and Shape:
solid
Molecular weight:
500.35
Estimated delivery in United States, on Monday 7 Feb 2022
AST-1306 TsOH
CAS:1050500-29-2
AST-1306 is a novel irreversible inhibitor of EGFR and ErbB2 with IC50 of 0.5 nM …
Formula:
C31H26ClFN4O5S
Purity:
99.52%
Color and Shape:
solid
Molecular weight:
621.08
Estimated delivery in United States, on Monday 7 Feb 2022
CYC116
CAS:693228-63-6
CYC116 is a potent inhibitor of Aurora A/B with Ki of 8.0 nM/9.2 nM, is …
Formula:
C18H20N6OS
Purity:
96.60%
Color and Shape:
solid
Molecular weight:
368.46
Estimated delivery in United States, on Monday 7 Feb 2022
DCC2036
CAS:1020172-07-9
DCC-2036 (Rebastinib) is a conformational control Bcr-Abl inhibitor for Abl1(WT, IC50: 0.8 nM) and Abl1(T315I, …
Formula:
C30H28FN7O3
Purity:
99.53%
Color and Shape:
solid
Molecular weight:
553.59
Estimated delivery in United States, on Monday 7 Feb 2022
PF03814735
CAS:942487-16-3
PF-03814735 is a novel, potent and reversible inhibitor of Aurora A/B with IC50of 0.8 nM/5 …
Formula:
C23H25F3N6O2
Purity:
98.0%
Molecular weight:
474.48
Estimated delivery in United States, on Monday 7 Feb 2022
3-Hydroxy Midostaurin
CAS:179237-49-1
3-Hydroxy Midostaurin (CGP 52421), a metabolite of PKC412, effectively inhibits FMS-like tyrosine kinase-3 (FLT3) autophosphorylation …
Formula:
C35H30N4O5
Purity:
98.00%
Color and Shape:
solid
Molecular weight:
586.64
Estimated delivery in United States, on Monday 7 Feb 2022
