IGF-1R
IGF-1R inhibitors are compounds that specifically target and inhibit the Insulin-like Growth Factor 1 Receptor (IGF-1R), a receptor tyrosine kinase involved in cellular growth, development, and survival. IGF-1R signaling plays a significant role in cancer progression, making these inhibitors valuable in oncology research. At CymitQuimica, we offer IGF-1R inhibitors to support your research in cancer biology, endocrinology, and targeted therapy development.
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NVP-TAE 226
CAS:761437-28-9
NVP-TAE 226: Potent FAK inhibitor, IC50=5.5nM, stronger vs Pyk2, IC50=3.5nM, weaker against IGF-1R, InsR, c-Met, …
Formula:
C23H25ClN6O3
Purity:
98.07% - 98.78%
Color and Shape:
Solid
Molecular weight:
468.94
Ref: TM-T1918
| 1mg | 48.00 € | ||
| 2mg | 63.00 € | ||
| 5mg | 101.00 € | ||
| 10mg | 163.00 € | ||
| 25mg | 264.00 € | ||
| 50mg | 378.00 € | ||
| 100mg | 567.00 € | ||
| 1mL*10mM (DMSO) | 101.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
GSK1838705A
CAS:1116235-97-2
GSK1838705A: IGF-1R inhibitor (IC50=2.0nM), IR (1.6nM), ALK (0.5nM), minimal other kinase impact.
Formula:
C27H29FN8O3
Purity:
100% - 99.63%
Color and Shape:
Solid
Molecular weight:
532.57
Ref: TM-T3079
| 1mg | 40.00 € | ||
| 2mg | 52.00 € | ||
| 5mg | 85.00 € | ||
| 10mg | 131.00 € | ||
| 25mg | 266.00 € | ||
| 50mg | 480.00 € | ||
| 1mL*10mM (DMSO) | 87.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
NVP-AEW541
CAS:475489-16-8
NVP-AEW541 (AEW541), a potent inhibitor of IGF-1R(IC50=150 nM) and InsR(IC50=140 nM), exhibits excellent efficiency and …
Formula:
C27H29N5O
Purity:
96.03% - 99.55%
Color and Shape:
Solid
Molecular weight:
439.55
Ref: TM-T6080
| 1mg | 48.00 € | ||
| 2mg | 65.00 € | ||
| 5mg | 96.00 € | ||
| 10mg | 153.00 € | ||
| 25mg | 271.00 € | ||
| 50mg | To inquire | ||
| 1mL*10mM (DMSO) | 96.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
NVP-ADW742
CAS:475488-23-4
NVP-ADW742 (ADW) is an IGF-1R inhibitor with IC50 of 0.17 μM, >16-fold more potent against …
Formula:
C28H31N5O
Purity:
99.79%
Color and Shape:
Solid
Molecular weight:
453.58
Ref: TM-T6079
| 1mg | 52.00 € | ||
| 2mg | 74.00 € | ||
| 5mg | 105.00 € | ||
| 10mg | 170.00 € | ||
| 25mg | 304.00 € | ||
| 50mg | 562.00 € | ||
| 100mg | 800.00 € | ||
| 1mL*10mM (DMSO) | 106.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
NT157
CAS:1384426-12-3
NT157, a small tyrphostin, inhibits IRS, IGF-1R, and STAT3 in TME, reducing cancer cell survival.
Formula:
C16H14BrNO5S
Purity:
97.55%
Color and Shape:
Solid
Molecular weight:
412.26
Ref: TM-T4605
| 1mg | 55.00 € | ||
| 5mg | 127.00 € | ||
| 10mg | 188.00 € | ||
| 25mg | 369.00 € | ||
| 50mg | 582.00 € | ||
| 100mg | 823.00 € | ||
| 1mL*10mM (DMSO) | 140.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
Ginsenoside Rg5
CAS:186763-78-0
Ginsenoside Rg5 shows promise for Alzheimer's, reduces inflammation, and aids vascular health without side effects.
Formula:
C42H70O12
Purity:
98% - 98.07%
Color and Shape:
Solid
Molecular weight:
767
Ref: TM-T6S1487
| 1mg | 113.00 € | ||
| 5mg | 265.00 € | ||
| 10mg | 426.00 € | ||
| 25mg | 702.00 € | ||
| 50mg | 938.00 € | ||
| 100mg | 1,320.00 € | ||
| 1mL*10mM (DMSO) | 360.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
Linsitinib
CAS:867160-71-2
OSI-906 (Linsitinib) is an oral inhibitor of IGF-1R with anti-cancer properties, potentially halting tumor growth …
Formula:
C26H23N5O
Purity:
98.98% - ≥95%
Color and Shape:
Solid
Molecular weight:
421.49
Ref: TM-T6017
| 2mg | 39.00 € | ||
| 5mg | 57.00 € | ||
| 10mg | 81.00 € | ||
| 25mg | 116.00 € | ||
| 50mg | 165.00 € | ||
| 100mg | 221.00 € | ||
| 1mL*10mM (DMSO) | 64.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
AZD-3463
CAS:1356962-20-3
AZD-3463 (ALK/IGF1R inhibitor) , an orally bioavailable ALK inhibitor (Ki: 0.75 nM), can inhibit IGF1R …
Formula:
C24H25ClN6O
Purity:
99.13%
Color and Shape:
Solid
Molecular weight:
448.95
Ref: TM-T1967
| 5mg | 52.00 € | ||
| 10mg | 79.00 € | ||
| 25mg | 123.00 € | ||
| 50mg | 197.00 € | ||
| 100mg | 350.00 € | ||
| 1mL*10mM (DMSO) | 58.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
AG1024
CAS:65678-07-1
AG1024 (Tyrphostin) suppresses IGF-1R autophosphorylation(IC50=7 μM), and is less potent for IR(IC50=57 μM).
Formula:
C14H13BrN2O
Purity:
98% - 99.37%
Color and Shape:
Solid
Molecular weight:
305.17
Ref: TM-T2693
| 2mg | 40.00 € | ||
| 5mg | 57.00 € | ||
| 10mg | 96.00 € | ||
| 25mg | 160.00 € | ||
| 50mg | 235.00 € | ||
| 100mg | 354.00 € | ||
| 1mL*10mM (DMSO) | 64.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
MID-1
CAS:312608-54-1
MID-1 is an inhibitor of MG53-IRS-1 (Mitsugumin 53-Insulin Receptor Substrate-1) interaction.
Formula:
C12H11N3O4S
Purity:
99.39%
Color and Shape:
Solid
Molecular weight:
293.3
Ref: TM-T8773
| 1mg | 50.00 € | ||
| 5mg | 97.00 € | ||
| 10mg | 145.00 € | ||
| 25mg | 259.00 € | ||
| 50mg | 383.00 € | ||
| 100mg | 545.00 € | ||
| 200mg | 740.00 € | ||
| 1mL*10mM (DMSO) | 109.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
AZ7550
CAS:1421373-99-0
AZ7550, an active metabolite of AZD9291, inhibits the activity of IGF1R (IC50: 1.6 μM).
Formula:
C27H31N7O2
Purity:
97.07%
Color and Shape:
Solid
Molecular weight:
485.58
Ref: TM-T13564
| 1mg | 131.00 € | ||
| 5mg | 286.00 € | ||
| 10mg | 424.00 € | ||
| 25mg | 702.00 € | ||
| 50mg | 938.00 € | ||
| 100mg | 1,311.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
MSDC 0160
CAS:146062-49-9
MSDC 0160 (CAY10415) is a prototype mTOT-modulating insulin sensitizer being used in trials studying the …
Formula:
C19H18N2O4S
Purity:
99.45% - 99.53%
Color and Shape:
Solid
Molecular weight:
370.42
Ref: TM-T2607
| 1mg | 35.00 € | ||
| 2mg | 50.00 € | ||
| 5mg | 77.00 € | ||
| 10mg | 99.00 € | ||
| 25mg | 154.00 € | ||
| 50mg | 197.00 € | ||
| 100mg | 350.00 € | ||
| 1mL*10mM (DMSO) | 82.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
MAZ51
CAS:163655-37-6
MAZ51 is a VEGFR-3 (Flt-4) tyrosine kinase inhibitor.
Formula:
C21H18N2O
Purity:
98.53%
Color and Shape:
Solid
Molecular weight:
314.38
Ref: TM-T8496
| 1mg | 40.00 € | ||
| 2mg | 51.00 € | ||
| 5mg | 85.00 € | ||
| 10mg | 124.00 € | ||
| 25mg | 243.00 € | ||
| 50mg | 406.00 € | ||
| 100mg | 607.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
XL228
CAS:898280-07-4
XL228 is an inhibitor of multi-targeted tyrosine kinase (IC50s: 5, 3.1, 1.6, 6.1, 2 nM …
Formula:
C22H31N9O
Purity:
99.07%
Color and Shape:
Solid
Molecular weight:
437.54
Ref: TM-T17267
| 1mg | 56.00 € | ||
| 2mg | 78.00 € | ||
| 5mg | 99.00 € | ||
| 10mg | 149.00 € | ||
| 25mg | 258.00 € | ||
| 50mg | 393.00 € | ||
| 100mg | 582.00 € | ||
| 1mL*10mM (DMSO) | 110.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
BMS-754807
CAS:1001350-96-4
BMS-754807 is an oral IGF-1R/InsR inhibitor with potential anti-cancer properties.
Formula:
C23H24FN9O
Purity:
98.86%
Color and Shape:
Solid
Molecular weight:
461.49
Ref: TM-T2349
| 1mg | 49.00 € | ||
| 2mg | 70.00 € | ||
| 5mg | 96.00 € | ||
| 10mg | 166.00 € | ||
| 25mg | 328.00 € | ||
| 50mg | 537.00 € | ||
| 100mg | 772.00 € | ||
| 1mL*10mM (DMSO) | 116.00 € |
Estimated delivery in United States, on Tuesday 20 May 2025
I-OMe-Tyrphostin AG 538
CAS:1094048-77-7
I-OMe-Tyrphostin AG 538: IGF-1R & PI5P4Kα inhibitor, ATP-competitive, IC50 of 1 µM, targets IGF-1R pathway, …
Formula:
C17H12INO5
Purity:
96.66%
Color and Shape:
Solid
Molecular weight:
437.19
Ref: TM-T11593
| 1mg | 56.00 € | ||
| 5mg | 119.00 € | ||
| 10mg | 187.00 € | ||
| 25mg | 432.00 € | ||
| 50mg | 638.00 € | ||
| 100mg | 908.00 € | ||
| 500mg | 1,825.00 € | ||
| 1mL*10mM (DMSO) | 131.00 € |
Estimated delivery in United States, on Tuesday 3 Jun 2025
Protonstatin-1
CAS:521972-99-6
Protonstatin-1: treats hypoglycemia & Alzheimer's, inhibits IGFIR kinase, used in cancer studies.
Formula:
C8H5NO2S2
Purity:
99.77%
Color and Shape:
Liquid
Molecular weight:
211.26
Ref: TM-T71812
| 1mg | 185.00 € | ||
| 5mg | 419.00 € | ||
| 10mg | 615.00 € | ||
| 25mg | 938.00 € | ||
| 50mg | 1,320.00 € | ||
| 100mg | 1,776.00 € | ||
| 500mg | 3,544.00 € |
Estimated delivery in United States, on Tuesday 3 Jun 2025
Tyrphostin AG 538
CAS:133550-18-2
Tyrphostin AG 538 is a chalcone compound, an IGF-1 receptor kinase inhibitor (IC₅0 : for …
Formula:
C16H11NO5
Purity:
99.73%
Color and Shape:
Soild
Molecular weight:
297.26
Ref: TM-T67707
| 1mg | 99.00 € | ||
| 5mg | 235.00 € | ||
| 10mg | 354.00 € | ||
| 25mg | 620.00 € | ||
| 50mg | 847.00 € | ||
| 100mg | 1,121.00 € |
Estimated delivery in United States, on Tuesday 17 Jun 2025
CL-A3-7
CAS:2763661-39-6
CL-A3-7 is a viral-cell fusion inhibitor targeting the RSVF protein. It functions by blocking the …
Formula:
C24H22Br2F2N2O3
Color and Shape:
Liquid
Molecular weight:
584.25
Ref: TM-T201641
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 15 Jul 2025
