IGF-1R
IGF-1R inhibitors are compounds that specifically target and inhibit the Insulin-like Growth Factor 1 Receptor (IGF-1R), a receptor tyrosine kinase involved in cellular growth, development, and survival. IGF-1R signaling plays a significant role in cancer progression, making these inhibitors valuable in oncology research. At CymitQuimica, we offer IGF-1R inhibitors to support your research in cancer biology, endocrinology, and targeted therapy development.
Found 98 products of "IGF-1R"
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Indirubin Derivative E804
CAS:Indirubin Derivative E804 is a potent insulin-like growth factor type 1 receptor (IGF1R) inhibitor with potential antitumor activity.Formula:C20H19N3O4Purity:98.54%Color and Shape:SolidMolecular weight:365.38Ref: TM-T11654
1mg42.00€5mg88.00€10mg124.00€25mg197.00€50mg293.00€100mg434.00€200mg622.00€1mL*10mM (DMSO)93.00€Dusigitumab
CAS:Dusigitumab (MEDI573) is a fully humanised monoclonal antibody targeting IGF1/IGF2, inhibiting IGF1/IGF2-induced IGF-1R phosphorylation.
Purity:95% - 95%Color and Shape:LiquidS961
CAS:S961: High-affinity IR antagonist; IC50: HIR-A 0.048 nM, HIR-B 0.027 nM, HIGF-IR 630 nM.Formula:C211H297N55O71S2Purity:98%Color and Shape:SolidMolecular weight:4804.13BMS-754807
CAS:BMS-754807 is an oral IGF-1R/InsR inhibitor with potential anti-cancer properties.Formula:C23H24FN9OPurity:99.69% - 99.94%Color and Shape:SolidMolecular weight:461.49Ref: TM-T2349
1mg50.00€2mg66.00€5mg90.00€10mg158.00€25mg310.00€50mg509.00€100mg732.00€1mL*10mM (DMSO)110.00€D-(+)-Sorbose
CAS:D-(+)-Sorbose, an enantiomer inhibiting disaccharidase, lowers glucose and insulin post-meal in rats, possibly preventing diabetes.Formula:C6H12O6Color and Shape:SolidMolecular weight:180.16KU14R
CAS:KU14R is a new I(3)-R antagonist, which selectively blocks the insulin secretory response to imidazolines.Formula:C13H14N2OPurity:98%Color and Shape:White SolidMolecular weight:214.26AZ12253801
CAS:AZ12253801 is a type 1 insulin-like growth factor receptor (IGF-1R) inhibitor.Formula:C21H22N8OPurity:98%Color and Shape:SolidMolecular weight:402.45IMP2-IN-2
CAS:IMP2-IN-2: potent, selective IMP2 inhibitor; IC50s: 120.9 μM (RNA_A), 236.7 μM (RNA_B); used in cancer research.Formula:C22H19F3N2O3SColor and Shape:SolidMolecular weight:448.46BM-131246
CAS:BM-131246 is an orally available and antidiabetic active thiazolidinedione derivative for the study of diabetes.Formula:C22H20N2O4SPurity:>99.99%Color and Shape:SolidMolecular weight:408.47H-1356
CAS:H-1356 is an insulin-like growth factor 1(IGF-I) analog that inhibits autophosphorylation of IGF-I receptor.Formula:C55H88N14O15S2Color and Shape:SolidMolecular weight:1249.5Protonstatin-1
CAS:Protonstatin-1: treats hypoglycemia & Alzheimer's, inhibits IGFIR kinase, used in cancer studies.Formula:C8H5NO2S2Purity:99.77%Color and Shape:SolidMolecular weight:211.26Ref: TM-T71812
1mg90.00€5mg215.00€10mg313.00€25mg537.00€50mg713.00€100mg982.00€200mg1,333.00€1mL*10mM (DMSO)236.00€NT219
CAS:NT219 is a dual inhibitor of insulin receptor substrate 1/2 (IRS1/2) and STAT3 that enhances the aggregation of misfolded prion proteins NT219 Effects.Formula:C16H14BrNO5SPurity:98.06% - 99.72%Color and Shape:SolidMolecular weight:412.26I-OMe-Tyrphostin AG 538
CAS:I-OMe-Tyrphostin AG 538: IGF-1R & PI5P4Kα inhibitor, ATP-competitive, IC50 of 1 µM, targets IGF-1R pathway, cytotoxic in nutrient-poor PANC1 cells.Formula:C17H12INO5Purity:98.8%Color and Shape:SolidMolecular weight:437.19Ref: TM-T11593
1mg56.00€5mg119.00€10mg187.00€25mg432.00€50mg638.00€100mg908.00€500mg1,825.00€1mL*10mM (DMSO)131.00€NBI-6024
CAS:NBI-6024, an altered peptide ligand (APL), serves as an epitope for interferon-gamma-producing T helper lymphocytes associated with inflammation in patientsFormula:C66H112N20O21Color and Shape:SolidMolecular weight:1521.72BMS-695735
CAS:BMS-695735: benzimidazole, inhibits IGF-1 receptor, broad antitumor effects, affects CYP3A4, low solubility, binds plasma proteins.Formula:C26H31ClFN7OColor and Shape:SolidMolecular weight:512.02Tyrphostin AG 538
CAS:Tyrphostin AG 538 is a chalcone compound, an IGF-1 receptor kinase inhibitor (IC₅0 : for 400 nM) that is potent, cell-permeable, reversible, and competitive.Formula:C16H11NO5Purity:98.75%Color and Shape:SoildMolecular weight:297.26IGF-1R inhibitor-4
CAS:IGF-1Rinhibitor-4 (compound 22) is a potent inhibitor of IGF-1R, demonstrating an inhibition rate of 63% at a concentration of 10 μM. This compound plays a significant role in cancer research.Formula:C13H15ClN4OColor and Shape:SolidMolecular weight:278.737AGL-2263
CAS:AGL-2263 is a blocker of insulin receptor (IR)Formula:C17H10N2O5Color and Shape:SolidMolecular weight:322.27
