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IGF-1R

IGF-1R

IGF-1R inhibitors are compounds that specifically target and inhibit the Insulin-like Growth Factor 1 Receptor (IGF-1R), a receptor tyrosine kinase involved in cellular growth, development, and survival. IGF-1R signaling plays a significant role in cancer progression, making these inhibitors valuable in oncology research. At CymitQuimica, we offer IGF-1R inhibitors to support your research in cancer biology, endocrinology, and targeted therapy development.

Found 86 products of "IGF-1R"

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  • NT219

    CAS:
    <p>NT219 is a dual inhibitor of insulin receptor substrate 1/2 (IRS1/2) and STAT3 that enhances the aggregation of misfolded prion proteins NT219 Effects.</p>
    Formula:C16H14BrNO5S
    Purity:98.06% - 99.72%
    Color and Shape:Solid
    Molecular weight:412.26
  • BMS-695735

    CAS:
    <p>BMS-695735: benzimidazole, inhibits IGF-1 receptor, broad antitumor effects, affects CYP3A4, low solubility, binds plasma proteins.</p>
    Formula:C26H31ClFN7O
    Color and Shape:Solid
    Molecular weight:512.02
  • Tyrphostin AG 538

    CAS:
    <p>Tyrphostin AG 538 is a chalcone compound, an IGF-1 receptor kinase inhibitor (IC₅0 : for 400 nM) that is potent, cell-permeable, reversible, and competitive.</p>
    Formula:C16H11NO5
    Purity:98.75%
    Color and Shape:Soild
    Molecular weight:297.26
  • CL-A3-7

    CAS:
    <p>CL-A3-7 is a viral-cell fusion inhibitor targeting the RSVF protein. It functions by blocking the interaction between the virus and the host's IGF1R, effectively inhibiting the infection of both wild-type and K394R mutant strains of RSV. This compound is suitable for use in antiviral drug development and resistance studies related to RSV.</p>
    Formula:C24H22Br2F2N2O3
    Color and Shape:Solid
    Molecular weight:584.25
  • IGF-1R inhibitor-4

    CAS:
    <p>IGF-1Rinhibitor-4 (compound 22) is a potent inhibitor of IGF-1R, demonstrating an inhibition rate of 63% at a concentration of 10 μM. This compound plays a significant role in cancer research.</p>
    Formula:C13H15ClN4O
    Color and Shape:Solid
    Molecular weight:278.737
  • AGL-2263

    CAS:
    <p>AGL-2263 is a blocker of insulin receptor (IR)</p>
    Formula:C17H10N2O5
    Color and Shape:Solid
    Molecular weight:322.27

    Ref: TM-T14142

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