Ubiquitination
Ubiquitination inhibitors are compounds that interfere with the process of ubiquitination, where proteins are tagged with ubiquitin molecules for degradation by the proteasome. These inhibitors are critical for studying protein turnover, signal transduction, and the regulation of various cellular processes. Ubiquitination plays a key role in many diseases, including cancer, neurodegenerative disorders, and immune system dysfunction. By modulating ubiquitination, these inhibitors can provide insights into the mechanisms of disease and open up new avenues for therapeutic intervention. At CymitQuimica, we offer a wide selection of high-quality ubiquitination inhibitors to support your research in cell biology, proteomics, and drug discovery.
Subcategories of "Ubiquitination"
Found 71 products of "Ubiquitination"
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
ML241
CAS:ML241 is a potent and selective inhibitors of p97 ATPase.Formula:C23H24N4OPurity:98%Color and Shape:SolidMolecular weight:372.46IU1-248
CAS:IU1-248 is a derivative of IU1. IU1-248 is a potent and selective USP14 inhibitor with an IC50 of 0.83 μM[1].Formula:C20H23N3O2Purity:99.3%Color and Shape:SolidMolecular weight:337.42Ref: TM-T9375
1mg50.00€5mg97.00€10mg160.00€25mg319.00€50mg449.00€100mg640.00€200mg893.00€1mL*10mM (DMSO)107.00€CYM5442
CAS:CYM5442 is an S1P agonist, targeting to Sphingosine.Formula:C23H27N3O4Purity:98.02% - 99.48%Color and Shape:SolidMolecular weight:409.48CB-5083
CAS:CB-5083 is a potent, selective, and orally bioavailable p97 AAA ATPase inhibitor ( IC50=11 nM).Formula:C24H23N5O2Purity:95.95% - 99.92%Color and Shape:SolidMolecular weight:413.47Ref: TM-T6796
1mg43.00€2mg56.00€5mg93.00€10mg130.00€25mg281.00€50mg444.00€100mg650.00€500mg1,369.00€1mL*10mM (DMSO)92.00€NMS-873
CAS:NMS-873 is a potent, selective allosteric VCP/p97 inhibitor.Formula:C27H28N4O3S2Purity:99.05% - 99.85%Color and Shape:SolidMolecular weight:520.67ML240
CAS:ML240 is a selective, ATP-competitive p97 inhibitor.Formula:C23H20N6OPurity:99.73% - >99.99%Color and Shape:SolidMolecular weight:396.44Ref: TM-T3535
1mg35.00€2mg50.00€5mg77.00€10mg105.00€25mg178.00€50mg295.00€100mg477.00€200mg677.00€1mL*10mM (DMSO)84.00€ML241 hydrochloride
CAS:ML241 is a potent and selective inhibitors of p97 ATPase.ML241 inhibits degradation of a p97-dependent but not a p97-independent proteasome substrate in a dual-Formula:C23H25ClN4OPurity:99.91% - 99.96%Color and Shape:SolidMolecular weight:408.92MID-1
CAS:MID-1 is an inhibitor of MG53-IRS-1 (Mitsugumin 53-Insulin Receptor Substrate-1) interaction.Formula:C12H11N3O4SPurity:99.39%Color and Shape:SolidMolecular weight:293.3Ref: TM-T8773
1mg52.00€5mg92.00€10mg138.00€25mg245.00€50mg363.00€100mg515.00€200mg700.00€1mL*10mM (DMSO)103.00€WSB1 Degrader 1
CAS:WSB1 Degrader 1 is a potent, orally active degrader of WD repeat and SOCS box-containing 1, exhibiting anti-cancer metastatic effects.Formula:C21H22N2O2Purity:98.57%Color and Shape:SolidMolecular weight:334.41VLX1570
CAS:VLX1570 is a competitive inhibitor of proteasome DUB activity with IC50 ranging from 4.2 uM to 8.6 uM. It has potent inhibition for USP14.Formula:C23H17F2N3O6Purity:98.53% - 99.91%Color and Shape:SolidMolecular weight:469.39Ref: TM-T4067
1mg96.00€2mg155.00€5mg259.00€10mg406.00€25mg680.00€50mg938.00€100mg1,301.00€1mL*10mM (DMSO)265.00€ML-323
CAS:ML323 is a reversible and effective USP1-UAF1 inhibitor in a Ub-Rho assay and in orthogonal gel-based assays using K63-linked di-Ub and Ub-PCNA as substrates.Formula:C23H24N6Purity:99.87% - 99.96%Color and Shape:SolidMolecular weight:384.48PR-619
CAS:PR-619 (2,6-Diamino-3,5-dithiocyanopyridine) is a DUB inhibitor. PR-619 induces endoplasmic reticulum stress and activates autophagy. Cost-effective and quality-assured.Formula:C7H5N5S2Purity:97.25% - >99.99%Color and Shape:SolidMolecular weight:223.28TCID
CAS:TCID (UCH-L3 Inhibitor)(IC50=0.6 μM) is a DUB inhibitor of ubiquitin C-terminal hydrolase L3. It has the 125-fold selectivity to L1.Formula:C9H2Cl4O2Purity:99.34%Color and Shape:SolidMolecular weight:283.92DKM 2-93
CAS:DKM 2-93 is a relatively selective inhibitor of UBA5(IC50 : 430 μM).Formula:C11H14ClNO3Purity:98.37% - 99.39%Color and Shape:SolidMolecular weight:243.69Skp2 Inhibitor C1
CAS:Skp2 Inhibitor C1 (SKPin C1)(SKPin C1) is a specific small molecule inhibitor of Skp2-mediated p27 degradation.Formula:C18H13BrN2O4S2Purity:97.36%Color and Shape:SolidMolecular weight:465.34Ref: TM-T4253
2mg34.00€5mg52.00€10mg85.00€25mg164.00€50mg264.00€100mg386.00€200mg537.00€1mL*10mM (DMSO)54.00€Subasumstat
CAS:Subasumstat (TAK-981) is a selective the SUMOylation enzymatic cascade inhibitor, has potential immune-activating and antineoplastic activities.Formula:C25H28ClN5O5S2Purity:97.02% - 98.22%Color and Shape:SolidMolecular weight:578.1BC-1382
CAS:BC-1382 is a potent ubiquitin E3 ligase HECTD2 inhibitor that specificly disrupts the HECTD2/PIAS1 interaction(IC50 of 5 nM).Formula:C23H29N3O5SPurity:99.15% - 99.94%Color and Shape:SolidMolecular weight:459.56Ref: TM-T8564
1mg81.00€5mg170.00€10mg250.00€25mg505.00€50mg730.00€100mg1,018.00€200mg1,369.00€1mL*10mM (DMSO)240.00€GS143
CAS:GS143 inhibits IκBα ubiquitination (IC50=5.2μM), suppresses NF-κB, and has anti-asthma properties without hindering proteasomes.Formula:C28H19FN2O4Purity:97.67%Color and Shape:SolidMolecular weight:466.46Ref: TM-T25465
2mg35.00€5mg55.00€10mg87.00€25mg161.00€50mg245.00€100mg358.00€200mg520.00€1mL*10mM (DMSO)57.00€LANOSTEROL
CAS:Lanosterol (3β-Hydroxy-8,24-lanostadiene) is a tetracyclic triterpenoid which is the compound from which all steroids are derived.Formula:C30H50OPurity:97.99% - 99.67%Color and Shape:SolidMolecular weight:426.72ICCB-19 hydrochloride
CAS:ICCB-19 hydrochloride (ICCB-19 HCl) is an inhibitor of TRADD (TNFRSF1A Associated Via Death Domain). It binds to a pocket on the TRADD-N.Formula:C12H22ClN3OSPurity:99.3%Color and Shape:SolidMolecular weight:291.84Ref: TM-T8931L
5mg34.00€10mg50.00€25mg90.00€50mg138.00€100mg198.00€200mg296.00€500mg469.00€1mL*10mM (DMSO)34.00€
