CymitQuimica logo
Ubiquitination

Ubiquitination

Ubiquitination inhibitors are compounds that interfere with the process of ubiquitination, where proteins are tagged with ubiquitin molecules for degradation by the proteasome. These inhibitors are critical for studying protein turnover, signal transduction, and the regulation of various cellular processes. Ubiquitination plays a key role in many diseases, including cancer, neurodegenerative disorders, and immune system dysfunction. By modulating ubiquitination, these inhibitors can provide insights into the mechanisms of disease and open up new avenues for therapeutic intervention. At CymitQuimica, we offer a wide selection of high-quality ubiquitination inhibitors to support your research in cell biology, proteomics, and drug discovery.

Subcategories of "Ubiquitination"

Found 107 products of "Ubiquitination"

Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
products per page.
  • Post-Translational Modification Compound Library
    Targetmol
    + Info

    Post-Translational Modification Compound Library

    <p>Contains xnum active small molecules for research related to post-translational modifications (PTMs);</p>
    Color and Shape:Odour Solid

    Ref: TM-L1620

  • CymitQuimica logo
    Targetmol
    + Info

    Skp2 inhibitor 3

    <p>Skp2 inhibitor 3 (E35), a potent antitumor agent, acts as a robust inhibitor of S-phase kinase-associated protein 2 (SKP2) with an IC50 of 4.86 μM for Skp2-Cks1 binding. It significantly suppresses colony formation and migration, while inducing cell cycle arrest in the S-phase.</p>
    Color and Shape:Odour Solid

    Ref: TM-T200788

  • E3 ligase Ligand 41
    Targetmol
    + Info

    E3 ligase Ligand 41

    CAS:
    <p>E3 Ligase Ligand 41 (Compound SI-13) serves as a ligand for the E3 ubiquitin ligase DCAF16. It is designed to connect with SLF through a linker, enabling the formation of KB03-SLF.</p>
    Formula:C13H12ClF3N2O4
    Color and Shape:Solid
    Molecular weight:352.69

    Ref: TM-T201480

  • USP8-IN-2
    Targetmol
    + Info

    USP8-IN-2

    CAS:
    <p>USP8-IN-2 is a potent inhibitor of the deubiquitinating enzymes USP7 and USP8, with an IC50 of 4.0 μM against USP8D.</p>
    Formula:C19H20ClF3N4OS
    Purity:99.92%
    Color and Shape:Solid
    Molecular weight:444.9

    Ref: TM-T67876

  • STD1T
    Targetmol
    + Info

    STD1T

    CAS:
    <p>STD1T is a USP2a inhibitor with anticancer activity that reduces levels of the cell cycle protein D1 protein in HCT116 colon cancer cells.</p>
    Formula:C19H19N3O4S2
    Purity:98.77%
    Color and Shape:Solid
    Molecular weight:417.5

    Ref: TM-T36970

  • USP8-IN-1
    Targetmol
    + Info

    USP8-IN-1

    CAS:
    <p>USP8-IN-1 is an inhibitor of USP8 with an IC 50 of 1.9 μM. USP8-IN-1 inhibits H1975 cell growth with a GI 50 of 82.04 μM [1].</p>
    Formula:C18H21N5O3S
    Purity:99.07%
    Color and Shape:Soild
    Molecular weight:387.46

    Ref: TM-T60146

  • MSC1094308
    Targetmol
    + Info

    MSC1094308

    CAS:
    <p>MSC1094308 is a reversible, non-ATP-competitive inhibitor targeting type II AAA ATPase (VCP/p97) and type I AAA ATPase (VPS4B) and affects protein degradation.</p>
    Formula:C29H29F3N2
    Color and Shape:Solid
    Molecular weight:462.55

    Ref: TM-T12114

  • USP25/28 inhibitor AZ1
    Targetmol
    + Info

    USP25/28 inhibitor AZ1

    CAS:
    <p>USP25/28 inhibitor AZ1 is a selective, orally active and non-competitive dual ubiquitin-specific protease USP25/28 inhibitor.Cost-effective and quality-assured.</p>
    Formula:C17H16BrF4NO2
    Purity:99.79% - 99.79%
    Color and Shape:Solid
    Molecular weight:422.21

    Ref: TM-T7685

  • XL177A
    Targetmol
    + Info

    XL177A

    CAS:
    <p>XL177A is a selective irreversible USP7 inhibitor(IC50 : 0.34 nM). XL177A elicits cancer cell killing through a p53-dependent mechanism.</p>
    Formula:C48H57ClN8O5
    Purity:98.75%
    Color and Shape:Solid
    Molecular weight:861.47

    Ref: TM-T9122

  • DUB-IN-3
    Targetmol
    + Info

    DUB-IN-3

    CAS:
    <p>DUB-IN-3 is a potent deubiquitinase (USP) enzyme inhibitor and the IC50 for USP8 is 0.56 μM.</p>
    Formula:C16H9N5O
    Purity:99.34%
    Color and Shape:Solid
    Molecular weight:287.28

    Ref: TM-T11112

  • BC-1382
    Targetmol
    + Info

    BC-1382

    CAS:
    <p>BC-1382 is a potent ubiquitin E3 ligase HECTD2 inhibitor that specificly disrupts the HECTD2/PIAS1 interaction(IC50 of 5 nM).</p>
    Formula:C23H29N3O5S
    Purity:99.15% - 99.94%
    Color and Shape:Solid
    Molecular weight:459.56

    Ref: TM-T8564

  • NSC632839
    Targetmol
    + Info

    NSC632839

    CAS:
    <p>NSC-632839 (Ubiquitin Isopeptidase Inhibitor II) is a nonselective isopeptidase inhibitor, which inhibits USP2 (EC50: 45±4 μM), USP7 (EC50: 37±1 μM), and SENP2</p>
    Formula:C21H22ClNO
    Purity:99.74% - 99.88%
    Color and Shape:Solid
    Molecular weight:339.86

    Ref: TM-T3951

  • PR-619
    Targetmol
    + Info

    PR-619

    CAS:
    <p>PR-619 (2,6-Diamino-3,5-dithiocyanopyridine) is a DUB inhibitor. PR-619 induces endoplasmic reticulum stress and activates autophagy. Cost-effective and quality-assured.</p>
    Formula:C7H5N5S2
    Purity:97.25% - >99.99%
    Color and Shape:Solid
    Molecular weight:223.28

    Ref: TM-T1862

  • ML240
    Targetmol
    + Info

    ML240

    CAS:
    <p>ML240 is a selective, ATP-competitive p97 inhibitor.</p>
    Formula:C23H20N6O
    Purity:99.73% - >99.99%
    Color and Shape:Solid
    Molecular weight:396.44

    Ref: TM-T3535

  • USP7/USP47 inhibitor
    Targetmol
    + Info

    USP7/USP47 inhibitor

    CAS:
    <p>USP7/USP47 inhibitor (USP7/47 inhibitor-1) is a selective ubiquitin-specific protease 7/47 (USP7/USP47) inhibitor, with EC50s of 0.42 μM and 1.0 μM,</p>
    Formula:C18H11Cl2N3O3S3
    Purity:98.5% - 98.71%
    Color and Shape:Solid
    Molecular weight:484.4

    Ref: TM-T4338

  • SJB2-043
    Targetmol
    + Info

    SJB2-043

    CAS:
    <p>SJB2-043 is an inhibitor of USP1-UAF1 ( IC50 : 544 nM).</p>
    Formula:C17H9NO3
    Purity:98.44%
    Color and Shape:Solid
    Molecular weight:275.26

    Ref: TM-T7678

  • NMS-873
    Targetmol
    + Info

    NMS-873

    CAS:
    <p>NMS-873 is a potent, selective allosteric VCP/p97 inhibitor.</p>
    Formula:C27H28N4O3S2
    Purity:99.05% - 99.85%
    Color and Shape:Solid
    Molecular weight:520.67

    Ref: TM-T1853

  • ML-323
    Targetmol
    + Info

    ML-323

    CAS:
    <p>ML323 is a reversible and effective USP1-UAF1 inhibitor in a Ub-Rho assay and in orthogonal gel-based assays using K63-linked di-Ub and Ub-PCNA as substrates.</p>
    Formula:C23H24N6
    Purity:99.87% - 99.96%
    Color and Shape:Solid
    Molecular weight:384.48

    Ref: TM-T1757

  • USP7-IN-8
    Targetmol
    + Info

    USP7-IN-8

    CAS:
    <p>Benzamide, 4-[6-amino-4-ethyl-5-(4-hydroxyphenyl)-3-pyridinyl]-N-methyl- is a selective ubiquitin-specific protease 7 (USP7) inhibitor with an IC50 of 1.4 μM.</p>
    Formula:C21H21N3O2
    Purity:99.31%
    Color and Shape:Solid
    Molecular weight:347.41

    Ref: TM-T9217

  • DUB-IN-2
    Targetmol
    + Info

    DUB-IN-2

    CAS:
    <p>Dub-in-2, with an IC50 value of 0.28 for USP8, is an effective deubiquitinase inhibitor.</p>
    Formula:C15H9N5O
    Purity:98.96%
    Color and Shape:Solid
    Molecular weight:275.26

    Ref: TM-T11111