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Ubiquitination

Ubiquitination

Ubiquitination inhibitors are compounds that interfere with the process of ubiquitination, where proteins are tagged with ubiquitin molecules for degradation by the proteasome. These inhibitors are critical for studying protein turnover, signal transduction, and the regulation of various cellular processes. Ubiquitination plays a key role in many diseases, including cancer, neurodegenerative disorders, and immune system dysfunction. By modulating ubiquitination, these inhibitors can provide insights into the mechanisms of disease and open up new avenues for therapeutic intervention. At CymitQuimica, we offer a wide selection of high-quality ubiquitination inhibitors to support your research in cell biology, proteomics, and drug discovery.

Subcategories of "Ubiquitination"

Found 107 products of "Ubiquitination"

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  • ML240
    Targetmol
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    ML240

    CAS:
    <p>ML240 is a selective, ATP-competitive p97 inhibitor.</p>
    Formula:C23H20N6O
    Purity:99.73% - >99.99%
    Color and Shape:Solid
    Molecular weight:396.44

    Ref: TM-T3535

  • MID-1
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    MID-1

    CAS:
    <p>MID-1 is an inhibitor of MG53-IRS-1 (Mitsugumin 53-Insulin Receptor Substrate-1) interaction.</p>
    Formula:C12H11N3O4S
    Purity:99.39%
    Color and Shape:Solid
    Molecular weight:293.3

    Ref: TM-T8773

  • USP7/USP47 inhibitor
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    USP7/USP47 inhibitor

    CAS:
    <p>USP7/USP47 inhibitor (USP7/47 inhibitor-1) is a selective ubiquitin-specific protease 7/47 (USP7/USP47) inhibitor, with EC50s of 0.42 μM and 1.0 μM,</p>
    Formula:C18H11Cl2N3O3S3
    Purity:98.5% - 98.71%
    Color and Shape:Solid
    Molecular weight:484.4

    Ref: TM-T4338

  • WSB1 Degrader 1
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    WSB1 Degrader 1

    CAS:
    <p>WSB1 Degrader 1 is a potent, orally active degrader of WD repeat and SOCS box-containing 1, exhibiting anti-cancer metastatic effects.</p>
    Formula:C21H22N2O2
    Purity:98.57%
    Color and Shape:Solid
    Molecular weight:334.41

    Ref: TM-T9236

  • VLX1570
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    VLX1570

    CAS:
    <p>VLX1570 is a competitive inhibitor of proteasome DUB activity with IC50 ranging from 4.2 uM to 8.6 uM. It has potent inhibition for USP14.</p>
    Formula:C23H17F2N3O6
    Purity:98.53% - 99.91%
    Color and Shape:Solid
    Molecular weight:469.39

    Ref: TM-T4067

  • ML-323
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    ML-323

    CAS:
    <p>ML323 is a reversible and effective USP1-UAF1 inhibitor in a Ub-Rho assay and in orthogonal gel-based assays using K63-linked di-Ub and Ub-PCNA as substrates.</p>
    Formula:C23H24N6
    Purity:99.87% - 99.96%
    Color and Shape:Solid
    Molecular weight:384.48

    Ref: TM-T1757

  • NMS-873
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    NMS-873

    CAS:
    <p>NMS-873 is a potent, selective allosteric VCP/p97 inhibitor.</p>
    Formula:C27H28N4O3S2
    Purity:99.05% - 99.85%
    Color and Shape:Solid
    Molecular weight:520.67

    Ref: TM-T1853

  • PR-619
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    PR-619

    CAS:
    <p>PR-619 (2,6-Diamino-3,5-dithiocyanopyridine) is a DUB inhibitor. PR-619 induces endoplasmic reticulum stress and activates autophagy. Cost-effective and quality-assured.</p>
    Formula:C7H5N5S2
    Purity:97.25% - >99.99%
    Color and Shape:Solid
    Molecular weight:223.28

    Ref: TM-T1862

  • 2-D08
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    2-D08

    CAS:
    <p>2-D08 is a synthetic flavone that inhibits sumoylation, also inhibits Axl with an IC50 of 0.49 nM.2-D08 showed anti-aggregatory and neuroprotective effect.</p>
    Formula:C15H10O5
    Purity:98.58% - 98.95%
    Color and Shape:Solid
    Molecular weight:270.24

    Ref: TM-T7379

  • DUB-IN-1
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    DUB-IN-1

    CAS:
    <p>DUB-IN-1, with an IC50 value of 0.24 for USP8, is an active inhibitor of ubiquitin-specific protease (USPs).</p>
    Formula:C20H11N5O
    Purity:98.33% - 98.96%
    Color and Shape:Solid
    Molecular weight:337.33

    Ref: TM-T11110

  • CB-5083
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    CB-5083

    CAS:
    <p>CB-5083 is a potent, selective, and orally bioavailable p97 AAA ATPase inhibitor ( IC50=11 nM).</p>
    Formula:C24H23N5O2
    Purity:95.95% - 99.92%
    Color and Shape:Solid
    Molecular weight:413.47

    Ref: TM-T6796

  • Skp2 Inhibitor C1
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    Skp2 Inhibitor C1

    CAS:
    <p>Skp2 Inhibitor C1 (SKPin C1)(SKPin C1) is a specific small molecule inhibitor of Skp2-mediated p27 degradation.</p>
    Formula:C18H13BrN2O4S2
    Purity:97.36%
    Color and Shape:Solid
    Molecular weight:465.34

    Ref: TM-T4253

  • ML364
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    ML364

    CAS:
    <p>ML364 is an inhibitor of ubiquitin specific peptidase 2 (USP2) and can be used for the research of breast cancer.</p>
    Formula:C24H18F3N3O3S2
    Purity:99.35% - >99.99%
    Color and Shape:Solid
    Molecular weight:517.54

    Ref: TM-T3555

  • BC-1382
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    BC-1382

    CAS:
    <p>BC-1382 is a potent ubiquitin E3 ligase HECTD2 inhibitor that specificly disrupts the HECTD2/PIAS1 interaction(IC50 of 5 nM).</p>
    Formula:C23H29N3O5S
    Purity:99.15% - 99.94%
    Color and Shape:Solid
    Molecular weight:459.56

    Ref: TM-T8564

  • NSC632839
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    NSC632839

    CAS:
    <p>NSC-632839 (Ubiquitin Isopeptidase Inhibitor II) is a nonselective isopeptidase inhibitor, which inhibits USP2 (EC50: 45±4 μM), USP7 (EC50: 37±1 μM), and SENP2</p>
    Formula:C21H22ClNO
    Purity:99.74% - 99.88%
    Color and Shape:Solid
    Molecular weight:339.86

    Ref: TM-T3951

  • SJB2-043
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    SJB2-043

    CAS:
    <p>SJB2-043 is an inhibitor of USP1-UAF1 ( IC50 : 544 nM).</p>
    Formula:C17H9NO3
    Purity:98.44%
    Color and Shape:Solid
    Molecular weight:275.26

    Ref: TM-T7678

  • DUB-IN-2
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    DUB-IN-2

    CAS:
    <p>Dub-in-2, with an IC50 value of 0.28 for USP8, is an effective deubiquitinase inhibitor.</p>
    Formula:C15H9N5O
    Purity:98.96%
    Color and Shape:Solid
    Molecular weight:275.26

    Ref: TM-T11111

  • GNE-6640
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    GNE-6640

    CAS:
    <p>GNE-6640: non-covalent USP7 inhibitor; IC50s: 0.75 µM (full), 0.43 µM (catalytic), 20.3 µM (USP43), 0.23 µM (Ub-MDM2).</p>
    Formula:C20H18N4O
    Purity:98.64%
    Color and Shape:Solid
    Molecular weight:330.38

    Ref: TM-T5461

  • USP7-IN-8
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    USP7-IN-8

    CAS:
    <p>Benzamide, 4-[6-amino-4-ethyl-5-(4-hydroxyphenyl)-3-pyridinyl]-N-methyl- is a selective ubiquitin-specific protease 7 (USP7) inhibitor with an IC50 of 1.4 μM.</p>
    Formula:C21H21N3O2
    Purity:99.31%
    Color and Shape:Solid
    Molecular weight:347.41

    Ref: TM-T9217

  • Subasumstat
    Targetmol
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    Subasumstat

    CAS:
    <p>Subasumstat (TAK-981) is a selective the SUMOylation enzymatic cascade inhibitor, has potential immune-activating and antineoplastic activities.</p>
    Formula:C25H28ClN5O5S2
    Purity:97.02% - 98.22%
    Color and Shape:Solid
    Molecular weight:578.1

    Ref: TM-T8428