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Ubiquitination

Ubiquitination

Ubiquitination inhibitors are compounds that interfere with the process of ubiquitination, where proteins are tagged with ubiquitin molecules for degradation by the proteasome. These inhibitors are critical for studying protein turnover, signal transduction, and the regulation of various cellular processes. Ubiquitination plays a key role in many diseases, including cancer, neurodegenerative disorders, and immune system dysfunction. By modulating ubiquitination, these inhibitors can provide insights into the mechanisms of disease and open up new avenues for therapeutic intervention. At CymitQuimica, we offer a wide selection of high-quality ubiquitination inhibitors to support your research in cell biology, proteomics, and drug discovery.

Subcategories of "Ubiquitination"

Found 107 products of "Ubiquitination"

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  • CYM5442
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    CYM5442

    CAS:
    <p>CYM5442 is an S1P agonist, targeting to Sphingosine.</p>
    Formula:C23H27N3O4
    Purity:98.02% - 99.48%
    Color and Shape:Solid
    Molecular weight:409.48

    Ref: TM-T2026

  • IU1-248
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    IU1-248

    CAS:
    <p>IU1-248 is a derivative of IU1. IU1-248 is a potent and selective USP14 inhibitor with an IC50 of 0.83 μM[1].</p>
    Formula:C20H23N3O2
    Purity:99.3%
    Color and Shape:Solid
    Molecular weight:337.42

    Ref: TM-T9375

  • LANOSTEROL
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    LANOSTEROL

    CAS:
    <p>Lanosterol (3β-Hydroxy-8,24-lanostadiene) is a tetracyclic triterpenoid which is the compound from which all steroids are derived.</p>
    Formula:C30H50O
    Purity:97.99% - 99.67%
    Color and Shape:Solid
    Molecular weight:426.72

    Ref: TM-T4970

  • USP1-IN-2
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    USP1-IN-2

    CAS:
    <p>USP1-IN-2 is a potent USP1 inhibitor with potential anti-tumor activity for the study of cancer.</p>
    Formula:C26H22F4N6O
    Purity:99.69% - 99.88%
    Color and Shape:Solid
    Molecular weight:510.486

    Ref: TM-T63518

  • BI8626
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    BI8626

    CAS:
    <p>BI8626 is a ubiquitin ligase inhibitor with protective effects against spontaneous dry syndrome in NOD/ShiLtj mice and inhibits the proliferation of CD4 T cells</p>
    Formula:C25H28N8
    Purity:98.66%
    Color and Shape:Solid
    Molecular weight:440.54

    Ref: TM-T14569

  • USP28-IN-4
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    USP28-IN-4

    CAS:
    <p>USP28-IN-4 is a USP28 inhibitor with anticancer activity that dose-dependently down-regulates cellular levels of c-Myc via the ubiquitin-proteasome system.</p>
    Formula:C22H18Cl2N2O3S
    Purity:98.48%
    Color and Shape:Solid
    Molecular weight:461.36

    Ref: TM-T74794

  • FT827
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    FT827

    CAS:
    <p>FT827 is a covalent inhibitor of USP7 that targets the catalytic center of the autoinhibitory apolipoprotein form of USP7 for cancer research.</p>
    Formula:C27H28N6O5S
    Purity:98.76%
    Color and Shape:Solid
    Molecular weight:548.61

    Ref: TM-T15351

  • DT204
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    DT204

    CAS:
    <p>DT204 is an SCFSkp2 inhibitor that reduces the binding of Skp2 to Cullin-1 and Commd1. It can be used to study multiple myeloma.</p>
    Formula:C19H13BrClNO5S
    Purity:99.17%
    Color and Shape:Solid
    Molecular weight:482.73

    Ref: TM-T71830

  • USP28-IN-3
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    USP28-IN-3

    CAS:
    <p>USP28-IN-3 is a USP28 inhibitor with anticancer activity that dose-dependently down-regulates cellular levels of c-Myc via the ubiquitin-proteasome system.</p>
    Formula:C23H20Cl2N2O3S
    Purity:99.92%
    Color and Shape:Solid
    Molecular weight:475.39

    Ref: TM-T74793

  • I-138
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    I-138

    CAS:
    <p>I-138 is an orally active and reversible inhibitor of USP1-UAF1.I-138 induces mono-ubiquitination of FANCD2 and PCNA and inhibits USP1 auto-cleavage in cells.</p>
    Formula:C26H23F3N6O
    Purity:99.41%
    Color and Shape:Solid
    Molecular weight:492.5

    Ref: TM-T73560

  • Smurf1-IN-1
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    Smurf1-IN-1

    CAS:
    <p>Smurf1-IN-1, a selective E3 ubiquitin protein ligase 1 (SMURF1) inhibitor, exhibits oral activity with an IC50 of 92 nM and demonstrates considerable efficacy</p>
    Formula:C24H29ClN6O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:468.98

    Ref: TM-T78721

  • OTUB1/USP8-IN-1
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    OTUB1/USP8-IN-1

    CAS:
    <p>OTUB1/USP8-IN-1 is an OTUB1/USP8 inhibitor with anticancer activity for the study of non-small cell lung cancer.</p>
    Formula:C22H16ClFN2O4
    Purity:98.59%
    Color and Shape:Soild
    Molecular weight:426.83

    Ref: TM-T72784

  • CB-5339
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    CB-5339

    CAS:
    <p>p97-IN-1 is a potent inhibitor of p97 with an IC 50 &lt;30 nM [1].</p>
    Formula:C24H24N6O
    Purity:97.66%
    Color and Shape:Soild
    Molecular weight:412.49

    Ref: TM-T60193

  • GSK2643943A
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    GSK2643943A

    CAS:
    <p>GSK2643943A is a deubiquitylating enzyme (DUB) inhibitor, with an IC 50 of 160 nM for USP20/Ub-Rho. GSK2643943A has anti-tumor efficacy.</p>
    Formula:C17H12FN3
    Purity:97.09%
    Color and Shape:Solid
    Molecular weight:277.3

    Ref: TM-T11485

  • SJB3-019A
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    SJB3-019A

    CAS:
    <p>SJB3-019A is a potent, potent and novel ubiquitin-specific protease 1 (USP1) inhibitor, which promotes ID1 degradation and cytotoxicity in K562 cells 5 times</p>
    Formula:C16H8N2O3
    Purity:99.72%
    Color and Shape:Solid
    Molecular weight:276.25

    Ref: TM-T12926

  • NAcM-OPT
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    NAcM-OPT

    CAS:
    <p>NAcM-OPT is a specific, reversible inhibitor targeting N-Acetyl-UBE2M interaction with DCN1 （IC50: 79 nM).</p>
    Formula:C23H29Cl2N3O
    Purity:99.93%
    Color and Shape:Solid
    Molecular weight:434.4

    Ref: TM-T5374

  • USP30 inhibitor 11
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    USP30 inhibitor 11

    CAS:
    <p>USP30 inhibitor 11 (USP30-IN-11) is a USP30 inhibitor that inhibits SVA and can be used in studies of cancer, mitochondrial dysfunction and Parkinson's.</p>
    Formula:C17H16N6O2S
    Purity:98.84% - 99.59%
    Color and Shape:Solid
    Molecular weight:368.41

    Ref: TM-T13267

  • P22074
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    P22074

    CAS:
    <p>P22074 is a USP7 inhibitor. It is not an active antagonist like its halogenated related compounds. p22074 has antitumour activity.</p>
    Formula:C12H9NO3S2
    Purity:>99.99%
    Color and Shape:Solid
    Molecular weight:279.33

    Ref: TM-T28284

  • USP22-IN-1
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    USP22-IN-1

    CAS:
    <p>USP22-IN-1 is a ubiquitin-specific peptidase 22 (USP22) inhibitor that can be used to treat proliferative diseases or cancer.</p>
    Formula:C22H18N4
    Purity:98.2%
    Color and Shape:Solid
    Molecular weight:338.41

    Ref: TM-T73151

  • Ubiquitination-IN-1
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    Ubiquitination-IN-1

    CAS:
    <p>Ubiquitination-IN-1 is an inhibitor of ubiquitination and Cksl-Skp2 protein-protein interaction (IC50: 0.17 μM).</p>
    Formula:C21H14F3N3O2S
    Purity:98.396% - 99.88%
    Color and Shape:Solid
    Molecular weight:429.42

    Ref: TM-T13244