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Ubiquitination

Ubiquitination

Ubiquitination inhibitors are compounds that interfere with the process of ubiquitination, where proteins are tagged with ubiquitin molecules for degradation by the proteasome. These inhibitors are critical for studying protein turnover, signal transduction, and the regulation of various cellular processes. Ubiquitination plays a key role in many diseases, including cancer, neurodegenerative disorders, and immune system dysfunction. By modulating ubiquitination, these inhibitors can provide insights into the mechanisms of disease and open up new avenues for therapeutic intervention. At CymitQuimica, we offer a wide selection of high-quality ubiquitination inhibitors to support your research in cell biology, proteomics, and drug discovery.

Subcategories of "Ubiquitination"

Found 69 products for "Ubiquitination".

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  • Cbl-b-IN-11

    CAS:
    Cbl-b-IN-11 (Compound 466) is an inhibitor of both casitas B-lineage lymphoma-b (Cbl-b) and c-Cbl, exhibiting half-maximal inhibitory concentrations (IC50s) of
    Formula:C31H35F5N6O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:602.64

    Ref: TM-T79898

    25mg
    2,295.00€
    50mg
    3,277.00€
    100mg
    4,104.00€
  • EA-B2L

    CAS:
    EA-B2L is an effective degrader of glutathione S-transferase (GSTP) with a DC50 of 48 μM. It is composed of Ethacrynic acid linked to Boc2Lys. EA-B2L plays a significant role in cancer research.
    Formula:C35H54Cl2N4O8
    Color and Shape:Solid
    Molecular weight:729.73

    Ref: TM-T201479

    10mg
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    50mg
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  • p97-IN-1

    CAS:
    p97-IN-1 is an orally active inhibitor of p97 with an IC50 of 26 nM. It significantly impedes the proliferation of tumor cells and is applicable for research in acute myeloid leukemia (AML).
    Formula:C25H26N6O2
    Color and Shape:Solid
    Molecular weight:442.51

    Ref: TM-T211078

    10mg
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    50mg
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  • Cbl-b-IN-26

    CAS:
    Cbl-b-IN-26 (Example A1) is an inhibitor of Cbl-b with a dissociation constant (Kd) of 34.6 nM. It is used in the research of chronic viral infections and cancer.
    Formula:C21H19F3N6
    Color and Shape:Solid
    Molecular weight:412.41

    Ref: TM-T200325

    25mg
    2,673.00€
    50mg
    3,312.00€
    100mg
    4,230.00€
  • BC-1293

    CAS:
    BC-1293 inhibits FBXO24, stabilizes DARS2, and elevates cytokines in mice, showing immunostimulatory potential for immune modulation research.
    Formula:C26H28N4O4S
    Purity:98.40%
    Color and Shape:White Solid
    Molecular weight:492.59

    Ref: TM-T89425

    1mg
    175.00€
    5mg
    434.00€
    10mg
    622.00€
    25mg
    973.00€
    50mg
    1,341.00€
    100mg
    1,765.00€
    200mg
    2,412.00€
  • NSC20116

    CAS:
    NSC20116 is a uracil derivative that specifically targets the Set-and-Ring (SRA) domain of the oncogene UHRF1. It binds to the 5-methylcytosine (5mC) recognition pocket within the UHRF1SRA domain, with a dissociation constant (Kd) of 362 nM. NSC20116 is applicable for cancer research.
    Formula:C4H4N4O3
    Molecular weight:156.1

    Ref: TM-T213072

    10mg
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    50mg
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  • PRC1-IN-1

    CAS:
    PRC1-IN-1 (compound RB-4) is an inhibitor of the polycomb repressive complex 1 (PRC1) with an IC50 of 2.3 μM. It targets RING1B-BMI1, RING1A-BMI1, and RING1B-PCGF1, exhibiting IC50 values of 2.8 μM, 2.6 μM, and 1.8 μM, respectively.
    Formula:C24H19ClFN3O2
    Color and Shape:Solid
    Molecular weight:435.878

    Ref: TM-T205306

    10mg
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    50mg
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  • Yucasin

    CAS:
    Yucasin is a highly potent inhibitor of auxin (IAA) biosynthesis that blocks the tryptophan-dependent pathway by specifically inhibiting the activity of YUCCA.
    Formula:C8H6ClN3S
    Purity:95.10%
    Color and Shape:White Solid
    Molecular weight:211.67

    Ref: TM-T201628

    5mg
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    10mg
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    1mg
    33.00€
  • Cbl-b-IN-3

    CAS:
    Cbl-b-IN-3 is a potent inhibitor of casitas b lineage lymphoma proto-oncogene-b (Cbl-b) (ic50 < 1 nM).Cost-effective and quality-assured.
    Formula:C30H34F3N5O
    Purity:97.63%
    Color and Shape:Yellow Solid
    Molecular weight:537.62

    Ref: TM-T63790

    1mg
    66.00€
    5mg
    145.00€
    1mL*10mM (DMSO)
    172.00€
    10mg
    192.00€
    25mg
    364.00€
    50mg
    558.00€
    100mg
    893.00€