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Autophagy

Autophagy

Autophagy inhibitors target the cellular process of autophagy, which involves the degradation and recycling of cellular components through lysosomes. Autophagy is a critical mechanism for maintaining cellular homeostasis, but its dysregulation is implicated in various diseases, including cancer, neurodegeneration, and infections. Inhibitors of autophagy can block this process, making them valuable tools for studying the role of autophagy in disease and developing therapeutic strategies. At CymitQuimica, we offer autophagy inhibitors to support your research in cell biology, oncology, and neurodegenerative diseases.

Found 1424 products of "Autophagy"

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  • KAN0438757

    CAS:
    <p>KAN0438757 is a selective and potent inhibitor of the metabolic kinase PFKFB3 with an IC50 of 0.19 μM.</p>
    Formula:C21H18FNO7S
    Purity:99.34%
    Color and Shape:Solid
    Molecular weight:447.43
  • Pravastatin sodium

    CAS:
    <p>Pravastatin sodium (CS-514 (sodium)), an HMG-CoA reductase inhibitor, inhibits sterol synthesis with IC50 of 5.6 μM.</p>
    Formula:C23H35NaO7
    Purity:97.14%
    Color and Shape:White Crystalline Powder
    Molecular weight:446.52
  • Raloxifene hydrochloride

    CAS:
    <p>Raloxifene HCl treats postmenopausal osteoporosis, acts as estrogen on bone/cholesterol, and blocks it in breast/uterus.</p>
    Formula:C28H28ClNO4S
    Purity:98% - 99.97%
    Color and Shape:Light Yellow Solid
    Molecular weight:510.044
  • LY2183240

    CAS:
    <p>LY2183240 inhibits fatty acid amide hydrolase (FAAH) activity (IC50 = 12.4 nM).</p>
    Formula:C17H17N5O
    Purity:99.26%
    Color and Shape:Solid
    Molecular weight:307.35
  • Ivermectin

    CAS:
    <p>Ivermectin (MK-933) is a glutamate-gated chloride channel (GluCls) activator, with antiparasitic activity.</p>
    Formula:C48H74O14
    Purity:94.11% - 99.71%
    Color and Shape:Solid
    Molecular weight:875.09
  • Clemastine fumarate

    CAS:
    <p>Clemastine fumarate (Meclastine (fumarate)) is a synthetic ethanolamine with anticholinergic, sedative, and histamine H1 antagonistic properties.</p>
    Formula:C25H30ClNO5
    Purity:99.52% - >99.99%
    Color and Shape:Colorless To Faintly Yellow Crystalline Powder Appearance White Or Almost White Crystalline Powder
    Molecular weight:459.97
  • Naringin

    CAS:
    <p>Naringin: flavanone glycoside with blood lipid-reducing, antioxidant, anticancer properties, inhibits cytochrome P450.</p>
    Formula:C27H32O14
    Purity:99.23%
    Color and Shape:Beige Creamish Powder Solid Solid Particulate/Powder
    Molecular weight:580.53
  • Sorafenib

    CAS:
    <p>Sorafenib (Bay 43-9006) is a multikinase inhibitor that inhibits Raf-1, B-Raf, VEGFR2, VEGFR3, VEGFR4, PDGFRβ, FLT3, c-Kit, and others (IC50=6/22/90/15/20/20/57</p>
    Formula:C21H16ClF3N4O3
    Purity:98% - 99.89%
    Color and Shape:Solid
    Molecular weight:464.82
  • Aumitin

    CAS:
    <p>Aumitin inhibits autophagy (IC50: 0.12-0.24μM), targets complex I, and blocks mitochondrial respiration.</p>
    Formula:C24H20ClN5O
    Purity:99.13%
    Color and Shape:Solid
    Molecular weight:429.9
  • Deferoxamine Mesylate

    CAS:
    <p>Deferoxamine Mesylate (DFOM) is an iron chelator and iron death inhibitor.</p>
    Formula:C26H52N6O11S
    Purity:94.68% - 99.8%
    Color and Shape:Solid
    Molecular weight:656.79
  • Oxidopamine hydrochloride

    CAS:
    <p>Oxidopamine hydrochloride (6-Hydroxydopamine hydrochloride) is an neurotransmitter dopamine antagonist.</p>
    Formula:C8H12ClNO3
    Purity:98.34% - 99.85%
    Color and Shape:Physical Description Beige Solid (Ntp 1992)
    Molecular weight:205.64
  • Isoliquiritigenin

    CAS:
    <p>Isoliquiritigenin (ISL) is a natural flavonoid that inhibits influenza virus and aldose reductase. Isoliquiritigenin has antitumor effect. Cost-effective and quality-assured.</p>
    Formula:C15H12O4
    Purity:97.61% - 99.44%
    Color and Shape:Powder
    Molecular weight:256.25
  • Letrozole

    CAS:
    <p>Letrozole (CGS 20267) is an Aromatase Inhibitor. The mechanism of action of letrozole is as an Aromatase Inhibitor.</p>
    Formula:C17H11N5
    Purity:98.67% - 99.84%
    Color and Shape:White To Off-Whitecrystalline Powder
    Molecular weight:285.3
  • Luteolin

    CAS:
    <p>Luteolin (Luteolol) belongs to the flavonoid group of natural products and is a Nrf2 inhibitor, PDE inhibitor.</p>
    Formula:C15H10O6
    Purity:96.61% - 99.71%
    Color and Shape:Solid
    Molecular weight:286.24
  • Erlotinib

    CAS:
    <p>Erlotinib (NSC-718781) is an EGFR inhibitor (IC50: 2 nM). It is used for the treatment of non-small cell lung cancer.</p>
    Formula:C22H23N3O4
    Purity:98.19% - 99.98%
    Color and Shape:White To Off-White Powder
    Molecular weight:393.44
  • Theophylline

    CAS:
    <p>Theophylline (1,3-Dimethylxanthine) is a methyl xanthine derivative from tea with diuretic, smooth muscle relaxant, bronchial dilation, cardiac and central</p>
    Formula:C7H8N4O2
    Purity:99.65% - 99.98%
    Color and Shape:White Solid Powder
    Molecular weight:180.16
  • Rhein

    CAS:
    <p>Rhein (NSC 38629) is an anthraquinone compound extracted from Polygonaceae Rheum Officinale with anti-inflammation and antitumor activities.</p>
    Formula:C15H8O6
    Purity:99.04%
    Color and Shape:Physical Description Yellow Needles (From Methanol) Or Yellow-Brown Powder (Ntp 1992)
    Molecular weight:284.22
  • Bergenin

    CAS:
    <p>Bergenin (Bengenin) is a polyphenol, which is an effective antinarcotic agent with antioxidant action.</p>
    Formula:C14H16O9
    Purity:99.55% - 99.60%
    Color and Shape:The Loose White Needle Crystal Powder Or Crystalline
    Molecular weight:328.27
  • Carvedilol phosphate hemihydrate

    CAS:
    <p>Carvedilol phosphate hemihydrate (BM 14190 phosphate hemihydrate) is the phosphate salt form of carvedilol, a racemic mixture and adrenergic blocking agent.</p>
    Formula:C24H26N2O4·5H2O·H3O4P
    Purity:99.24% - 99.98%
    Color and Shape:Solid
    Molecular weight:513.49
  • Rosuvastatin calcium

    CAS:
    <p>Rosuvastatin calcium (ZD4522) , a selective and competitive inhibitor of hepatic hydroxymethyl-glutaryl coenzyme A (HMG-CoA) reductase, has antilipidemic</p>
    Formula:(C22H27FN3O6S)Ca
    Purity:98.21% - 99.68%
    Color and Shape:White To Off-White Crystalline Solid
    Molecular weight:1001.14