Autophagy
Autophagy inhibitors target the cellular process of autophagy, which involves the degradation and recycling of cellular components through lysosomes. Autophagy is a critical mechanism for maintaining cellular homeostasis, but its dysregulation is implicated in various diseases, including cancer, neurodegeneration, and infections. Inhibitors of autophagy can block this process, making them valuable tools for studying the role of autophagy in disease and developing therapeutic strategies. At CymitQuimica, we offer autophagy inhibitors to support your research in cell biology, oncology, and neurodegenerative diseases.
Found 1529 products for "Autophagy".
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TRAF6 peptide TFA
TRAF6 peptide TFA, a specific inhibitor of the TRAF6-p62 interaction, significantly inhibits NGF-dependent ubiquitination of TrkA.Formula:C145H238N34O44·xC2HF3O2Purity:98%Color and Shape:SolidMolecular weight:3161.64 (free acid)Rosuvastatin-D3 Sodium
CAS:Rosuvastatin D3 Sodium is deuterium labeled Rosuvastatin, which is a competitive HMG-CoA reductase inhibitor(IC50 of 11 nM).Formula:C22H24D3FN3NaO6SPurity:98%Color and Shape:SolidMolecular weight:506.54Loperamide-D6 hydrochloride
CAS:Loperamide D6 HCl: Deuterium-enriched opioid for diarrhea.Formula:C29H34Cl2N2O2Purity:98%Color and Shape:SolidMolecular weight:519.54Loperamide hydrochloride (Standard)
CAS:Loperamide hydrochloride (Standard) is the standard substance of Loperamide hydrochloride, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Loperamide hydrochloride (ADL 2-1294) is a synthetic, piperidine derivative and opioid agonist with antidiarrheal activity.Formula:C29H34Cl2N2O2Molecular weight:513.50Wortmannin (Standard)
CAS:Wortmannin (Standard) is the standard substance of Wortmannin, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Wortmannin (SL-2052) is a PI3K inhibitor (IC50=3 nM) that is covalent and irreversible. Wortmannin is also an inhibitor of PlK1 and PlK3 (IC50=5.8/48 nM) that blocks autophagy.Formula:C23H24O8Molecular weight:428.43Ezetimibe-D4
CAS:Ezetimibe D4, a deuterium-labeled variant of Ezetimibe, functions as an inhibitor of Niemann-Pick C1-like1 (NPC1L1) and is recognized for its potent activationFormula:C24H21F2NO3Purity:98%Color and Shape:SolidMolecular weight:413.45Nitrendipine (Standard)
CAS:Nitrendipine (Standard) is the standard substance of Nitrendipine, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Nitrendipine (BAY-E-5009) is a calcium channel blocker with marked vasodilator action. It is an effective antihypertensive agent and differs from other calcium channel blockers in that it does not reduce glomerular filtration rate and is mildly natriuretic, rather than sodium retentive.Formula:C18H20N2O6Molecular weight:360.36Imiquimod (Standard)
CAS:Imiquimod (Standard) is the standard substance of Imiquimod, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Imiquimod (R 837) is an immune response modifier and a toll-like receptor 7 (TLR7) agonist with antiviral and antitumor effects. It is used in the study of external genital warts, perianal warts, cancer, and COVID-19, and is commonly employed to induce psoriasis models.Formula:C14H16N4Molecular weight:240.30Pemetrexed disodium heptahydrate
CAS:Pemetrexed disodium heptahydrate (LY231514) is an antifolate that inhibits TS, DHFR and GARFT, inhibits precursor purine and pyrimidine nucleotides.Formula:C20H33N5Na2O13Purity:99.78%Color and Shape:White SolidMolecular weight:597.49Rapalink-1
CAS:Rapalink-1 is an mTOR inhibitor that inhibits the mTORC1-4E-BP1 pathway in mice.Formula:C91H138N12O24Purity:98%Color and Shape:White ViscousMolecular weight:1784.14BI-9627 hydrochloride
CAS:BI-9627 hydrochloride is a potent NHE1 inhibitor (IC₅₀ 6 nM, 31 nM), highly selective over NHE2, inactive on NHE3, regulating pH and autophagy.Formula:C16H20ClF3N4O2Purity:99.91%Color and Shape:White SolidMolecular weight:392.8Erlotinib-D6 hydrochloride
CAS:Erlotinib Hydrochloride inhibits purified EGFR kinase with an IC50 of 2 nM. Erlotinib D6 hydrochloride a deuterium labeled Erlotinib Hydrochloride.Formula:C22H24ClN3O4Purity:98%Color and Shape:SolidMolecular weight:435.93PS372424 hydrochloride
CAS:PS372424 hydrochloride,CXCR3 agonist. Anti-inflammatory. Inhibits T-cell migration.Formula:C33H45ClN6O4Purity:95.03%Color and Shape:Transparent ViscousMolecular weight:625.2Ponatinib-D8
CAS:Ponatinib D8 is a deuterium-enriched, oral multi-kinase inhibitor (Abl, PDGFRα, VEGFR2, FGFR1, Src; IC50s: 0.37-5.4 nM).Formula:C29H27F3N6OPurity:98%Color and Shape:SolidMolecular weight:540.61Guanidine hydrochloride (Standard)
CAS:Guanidine hydrochloride (Standard) is the standard substance of Guanidine hydrochloride, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Guanidine hydrochloride (Aminoformamidine Hydrochloride) is a strong organic base existing primarily as guanidium ions at physiological pH. It is found in the urine as a normal product of protein metabolism. It is also used in laboratory research as a protein denaturant.Formula:CH6ClN3Color and Shape:SolidMolecular weight:95.53Clotrimazole (Standard)
CAS:Clotrimazole (Standard) is the standard substance of Clotrimazole, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Clotrimazole (FB 5097), an imidazole derivative with a broad spectrum of antimycotic activity, inhibits biosynthesis of the sterol ergostol.Formula:C22H17ClN2Color and Shape:SolidMolecular weight:344.84Atorvastatin hemicalcium salt (Standard)
CAS:Atorvastatin hemicalcium salt (Standard) is the standard substance of Atorvastatin hemicalcium salt, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Atorvastatin hemicalcium salt (Atorvastatin Calcium) is an HMG-CoA reductase inhibitor with oral activity. Atorvastatin hemicalcium salt is used to lower cholesterol.Formula:C33H34FN2O5CaColor and Shape:SolidMolecular weight:577.67Colistin sulfate (Standard)
CAS:Colistin sulfate (Standard) is the standard substance of Colistin sulfate, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Colistin sulfate (Colistin sulfate (1066-17-7 free base)) is a cyclic polypeptide antibiotic from Bacillus colistinus, composed of Polymyxins E1 and E2.Color and Shape:SolidRegorafenib-D3
CAS:Regorafenib D3 is a deuterium labeled Regorafenib. Regorafenib is a multi-targeted receptor inhibitor of tyrosine kinase.Formula:C21H15ClF4N4O3Purity:98%Color and Shape:SolidMolecular weight:485.83Anti-LRRK2 Antibody (1C773)
Anti-LRRK2 Antibody (1C773) is an antibody targeting LRRK2. Anti-LRRK2 Antibody (1C773) can be used in ELISA, IHC.Color and Shape:Odour Liquid
