Autophagy
Autophagy inhibitors target the cellular process of autophagy, which involves the degradation and recycling of cellular components through lysosomes. Autophagy is a critical mechanism for maintaining cellular homeostasis, but its dysregulation is implicated in various diseases, including cancer, neurodegeneration, and infections. Inhibitors of autophagy can block this process, making them valuable tools for studying the role of autophagy in disease and developing therapeutic strategies. At CymitQuimica, we offer autophagy inhibitors to support your research in cell biology, oncology, and neurodegenerative diseases.
Found 1459 products of "Autophagy"
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Ixazomib citrate
CAS:Ixazomib citrate (MLN9708), a prodrug of Ixazomib (MMLN-2238), is an oral 2nd-gen proteasome inhibitor with anti-cancer potential (IC50: 3.4 nM).Formula:C20H23BCl2N2O9Purity:98.37% - >99.99%Color and Shape:SolidMolecular weight:517.123-Bromopyruvic acid
CAS:<p>3-Bromopyruvic acid (Hexokinase II Inhibitor II, 3-BP) is a hexokinase II inhibitor with Ki of 2.4 mM for glycolysis/hexokinase inhibition.</p>Formula:C3H3BrO3Purity:95% - 99.644%Color and Shape:White To Pale Yellow Crystalline PowderMolecular weight:166.96Lys05
CAS:Lys05, a potent autophagy inhibitor, outperforms HCQ in cancer treatment, showing promise for drug development.Formula:C23H26Cl5N5Purity:99.13% - 99.55%Color and Shape:SolidMolecular weight:549.75MK-2206 dihydrochloride
CAS:<p>MK-2206 dihydrochloride (MK-2206 2HCl) is a variant Akt inhibitor that inhibits Akt1, Akt2, and Akt3 (IC50=8/12/65 nM) with orally active, highly potent and</p>Formula:C25H23Cl2N5OPurity:99.228% - 99.94%Color and Shape:SolidMolecular weight:480.39Retro-2
CAS:<p>Retro-2 (2-{[(5-methyl-2-thienyl)methylene]amino}) is a plant toxin ricin inhibitor, it protects HeLa cells against Ricin, Stx1 and Stx2.</p>Formula:C19H16N2OSPurity:98.15%Color and Shape:SolidMolecular weight:320.41Bicyclol
CAS:<p>Bicyclol is an oral anti-hepatitis drug, decreasing ALT/AST levels by 50% and inhibiting HBV/HCV, boosting efficacy with interferon/lamivudine/adefovir.</p>Formula:C19H18O9Purity:99.64% - 99.85%Color and Shape:SolidMolecular weight:390.34Fasudil hydrochloride hydrate
CAS:Fasudil HCl hydrate is a ROCK inhibitor that hinders mature CCM development and lowers portal pressure in cirrhotic rats.Formula:C28H38Cl2N6O5S2Color and Shape:SolidMolecular weight:673.67Diosgenin glucoside
CAS:<p>Diosgenin glucoside (Trillin) and other synthetic glycosides with similar activities may be of use in the management of hypercholesterolemia and atherosclerosis</p>Formula:C33H52O8Purity:97.17% - 99.44%Color and Shape:SolidMolecular weight:576.76PD146176
CAS:<p>PD146176 (NSC-168807) is an inhibitor of 15-Lipoxygenase (15-LO) , it inhibits rabbit reticulocyte 15-LO with Ki of 197 nM and IC50 of 0.54 μM.</p>Formula:C15H11NSPurity:98.00%Color and Shape:SolidMolecular weight:237.32Schisandrol B
CAS:Schisandrol B fights neuroinflammation, liver/renal damage, and reduces cell growth via multiple signaling pathways.Formula:C23H28O7Purity:99.14% - 99.95%Color and Shape:SolidMolecular weight:416.46FIPI HCl
CAS:<p>FIPI: Selective phospholipase D inhibitor, blocks mercury-induced lipid signals, protects aortic cells.</p>Formula:C23H25ClFN5O2Color and Shape:SolidMolecular weight:457.93Brefeldin A
CAS:<p>Brefeldin A (Cyanein) belongs to the class of macrolide antibiotics and is an ATPase inhibitor (IC50=0.2 μM).</p>Formula:C16H24O4Purity:96.45% - 99.89%Color and Shape:White SolidMolecular weight:280.36Tacrolimus monohydrate
CAS:<p>Tacrolimus monohydrate (LCP-Tacro) is a macrolide from the culture broth of a strain of Streptomyces tsukubaensis, binds to FKBP to form a complex.</p>Formula:C44H71NO13Purity:97.07% - 98.05%Color and Shape:SolidMolecular weight:822.05Lapatinib tosylate
CAS:Lapatinib tosylate (GW572016) is an oral ErbB-2/EGFR inhibitor with IC50s of 10.2 nM (EGFR) & 9.8 nM (ErbB-2).Formula:C36H34ClFN4O7S2Color and Shape:SolidMolecular weight:753.26Sanguinarine
CAS:<p>Sanguinarine (Pseudochelerythrine) is a specific inhibitor of Rac1b with anti-microbial, anti-oxidant and anti-inflammatory properties.</p>Formula:C20H14NO4Purity:99.04% - 99.76%Color and Shape:SolidMolecular weight:332.33Idarubicin
CAS:<p>Idarubicin, a potent oral anthracycline, halts DNA/RNA replication and synthesis, damages DNA, and inhibits microbial growth.</p>Formula:C26H27NO9Color and Shape:SolidMolecular weight:497.49ABT-737
CAS:<p>ABT-737 is a BH3 mimetic and an inhibitor of Bcl-2, Bcl-xL, and Bcl-w. ABT-737 exhibits antitumor activity and anti-aging activity. Cost-effective and quality-assured.</p>Formula:C42H45ClN6O5S2Purity:98.15% - >99.99%Color and Shape:SolidMolecular weight:813.43Hoechst 33342 trihydrochloride
CAS:<p>Hoechst 33342 trihydrochloride (bisBenzimide H 33342 trihydrochloride;HOE 33342 trihydrochloride) is a membrane permeant DNA stain with blue fluorescence.</p>Formula:C27H31Cl3N6OPurity:98.73% - ≥98%Color and Shape:SolidMolecular weight:561.93MRT68921 HCl
CAS:<p>MRT68921 hydrochloride is a potent inhibitor of both ULK1 and ULK2 (IC50s: 2.9 and 1.1 nM, respectively).</p>Formula:C25H34N6O·HClPurity:99.86% - 99.98%Color and Shape:SolidMolecular weight:471.04Oprozomib
CAS:<p>Oprozomib inhibits 20S proteasome β5/LMP7, is orally available, and may have cancer-fighting properties. IC50: β5 - 36 nM; LMP7 - 82 nM.</p>Formula:C25H32N4O7SPurity:98% - 99.87%Color and Shape:SolidMolecular weight:532.61
