Autophagy
Autophagy inhibitors target the cellular process of autophagy, which involves the degradation and recycling of cellular components through lysosomes. Autophagy is a critical mechanism for maintaining cellular homeostasis, but its dysregulation is implicated in various diseases, including cancer, neurodegeneration, and infections. Inhibitors of autophagy can block this process, making them valuable tools for studying the role of autophagy in disease and developing therapeutic strategies. At CymitQuimica, we offer autophagy inhibitors to support your research in cell biology, oncology, and neurodegenerative diseases.
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Dantrolene sodium hemiheptahydrate
CAS:24868-20-0
Dantrolene depresses excitation-contraction coupling in skeletal muscle by binding to the ryanodine receptor 1 and …
Formula:
C14H9N4NaO5·5H2O
Purity:
98.52%
Color and Shape:
Orange Powder
Molecular weight:
399.29
Ref: TM-T4054
| 1g | 123.00 € | ||
| 100mg | 35.00 € | ||
| 500mg | 94.00 € | ||
| 1mL*10mM (DMSO) | 36.00 € |
Estimated delivery in United States, on Wednesday 20 Nov 2024
BIX-01294
CAS:935693-62-2
BIX-01294 is an G9a Histone Methyltransferase inhibitor(IC50 : 1.9 μM).
Formula:
C28H38N6O2
Purity:
99.31%
Color and Shape:
Solid
Molecular weight:
490.64
Ref: TM-T7697
| 1mg | 40.00 € | ||
| 2mg | 51.00 € | ||
| 5mg | 83.00 € | ||
| 10mg | 115.00 € | ||
| 25mg | 203.00 € | ||
| 50mg | 343.00 € | ||
| 100mg | 510.00 € | ||
| 200mg | 723.00 € | ||
| 1mL*10mM (DMSO) | 130.00 € |
Estimated delivery in United States, on Wednesday 20 Nov 2024
PR-619
CAS:2645-32-1
PR-619 (2,6-Diamino-3,5-dithiocyanopyridine) is a DUB inhibitor. PR-619 induces endoplasmic reticulum stress and activates autophagy. Cost-effective …
Formula:
C7H5N5S2
Purity:
100% - 99.83%
Color and Shape:
Solid
Molecular weight:
223.28
Ref: TM-T1862
| 5mg | 49.00 € | ||
| 10mg | 60.00 € | ||
| 25mg | 90.00 € | ||
| 50mg | 109.00 € | ||
| 100mg | 153.00 € | ||
| 200mg | 223.00 € | ||
| 500mg | 365.00 € |
Estimated delivery in United States, on Wednesday 20 Nov 2024
Rosiglitazone
CAS:122320-73-4
Rosiglitazone (BRL49653) is a PPARγ agonist, TRPC5 activator, and TRPM3 inhibitor with oral activity.
Formula:
C18H19N3O3S
Purity:
98.61% - 99.87%
Color and Shape:
White To Off-White Crystalline Powder
Molecular weight:
357.43
Ref: TM-T0334
| 25mg | 44.00 € | ||
| 50mg | 56.00 € | ||
| 100mg | 93.00 € | ||
| 200mg | 147.00 € | ||
| 500mg | 230.00 € | ||
| 1mL*10mM (DMSO) | 57.00 € |
Estimated delivery in United States, on Wednesday 20 Nov 2024
AZD-3463
CAS:1356962-20-3
AZD-3463 (ALK/IGF1R inhibitor) , an orally bioavailable ALK inhibitor (Ki: 0.75 nM), can inhibit IGF1R …
Formula:
C24H25ClN6O
Purity:
99.13%
Color and Shape:
Solid
Molecular weight:
448.95
Ref: TM-T1967
| 5mg | 52.00 € | ||
| 10mg | 78.00 € | ||
| 25mg | 121.00 € | ||
| 50mg | 193.00 € | ||
| 100mg | 343.00 € | ||
| 1mL*10mM (DMSO) | 58.00 € |
Estimated delivery in United States, on Wednesday 20 Nov 2024
Schisandrin B
CAS:61281-37-6
Schisandrin B (Schisandrin B (Sch B)) has an antioxidant effect on rodent liver and heart.
Formula:
C23H28O6
Purity:
100% - 99.84%
Color and Shape:
Solid
Molecular weight:
400.46
Ref: TM-T2925
| 1mg | 41.00 € | ||
| 5mg | 86.00 € | ||
| 10mg | 124.00 € | ||
| 25mg | 226.00 € | ||
| 50mg | 405.00 € | ||
| 100mg | 587.00 € | ||
| 500mg | 1,233.00 € | ||
| 1mL*10mM (DMSO) | 94.00 € |
Estimated delivery in United States, on Wednesday 20 Nov 2024
(R)-(-)-Gossypol acetic acid
CAS:866541-93-7
(R)-(-)-Gossypol acetic acid binds Bcl-2, Bcl-xL, Mcl-1 (Ki: 0.32, 0.48, 0.18 μM); no BIR3/BID inhibition. …
Formula:
C30H30O8·C2H4O2
Purity:
96.73% - 99.5%
Color and Shape:
Solid
Molecular weight:
578.61
Ref: TM-T6396
| 1g | 1,341.00 € | ||
| 2mg | 39.00 € | ||
| 5mg | 57.00 € | ||
| 10mg | 87.00 € | ||
| 25mg | 168.00 € | ||
| 50mg | 279.00 € | ||
| 100mg | 458.00 € | ||
| 500mg | 994.00 € |
Estimated delivery in United States, on Wednesday 20 Nov 2024
Tripterin
CAS:34157-83-0
Tripterin (Celastrol) is an proteasome inhibitor for the chymotrypsin-like activity of a purified 20S proteasome …
Formula:
C29H38O4
Purity:
99.48% - 99.8%
Color and Shape:
Red Crystalline Powder
Molecular weight:
450.61
Ref: TM-T3028
| 5mg | 55.00 € | ||
| 10mg | 83.00 € | ||
| 25mg | 102.00 € | ||
| 50mg | 127.00 € | ||
| 100mg | 170.00 € | ||
| 1mL*10mM (DMSO) | 61.00 € |
Estimated delivery in United States, on Wednesday 20 Nov 2024
AT9283
CAS:896466-04-9
AT9283 (J-504568) is an effective multi-targeted inhibitor of JAK2(IC50=1.2 nM) and JAK3(IC50=1.1 nM), Aurora A, …
Formula:
C19H23N7O2
Purity:
99.87% - 99.98%
Color and Shape:
Solid
Molecular weight:
381.43
Ref: TM-T3068
| 1mg | 46.00 € | ||
| 2mg | 59.00 € | ||
| 5mg | 93.00 € | ||
| 10mg | 167.00 € | ||
| 25mg | 294.00 € | ||
| 50mg | 488.00 € | ||
| 100mg | 711.00 € | ||
| 1mL*10mM (DMSO) | 96.00 € |
Estimated delivery in United States, on Wednesday 20 Nov 2024
Afzelin
CAS:482-39-3
Afzelin (Kaempferol-3-O-rhamnoside) has several cellular activities such as DNA-protective, antibacterial, antioxidant, and anti-inflammatory as well …
Formula:
C21H20O10
Purity:
99.38%
Color and Shape:
Solid
Molecular weight:
432.38
Ref: TM-TN1362
| 1mg | 47.00 € | ||
| 5mg | 121.00 € | ||
| 10mg | 173.00 € | ||
| 25mg | 289.00 € | ||
| 50mg | 429.00 € | ||
| 100mg | 628.00 € |
Estimated delivery in United States, on Wednesday 20 Nov 2024
Icaritin
CAS:118525-40-9
Icaritin (Anhydroicaritin) has hormone regulation activity and cardiovascular function improvement activity.
Formula:
C21H20O6
Purity:
97.69% - 98.96%
Color and Shape:
Solid
Molecular weight:
368.38
Ref: TM-T3398
| 1mg | 35.00 € | ||
| 5mg | 73.00 € | ||
| 10mg | 118.00 € | ||
| 25mg | 188.00 € | ||
| 50mg | 273.00 € | ||
| 100mg | 407.00 € | ||
| 1mL*10mM (DMSO) | 74.00 € |
Estimated delivery in United States, on Wednesday 20 Nov 2024
Cysteamine hydrochloride
CAS:156-57-0
Cysteamine hydrochloride (Thioethanolamine Hydrochloride) is an agent for the treatment of nephropathic cystinosis and an …
Formula:
C2H7NS·HCl
Purity:
99.34%
Color and Shape:
White Crystalline Powder With A Strong And Disagreeable Smell
Molecular weight:
113.61
Ref: TM-T6460
| 5g | 34.00 € |
Estimated delivery in United States, on Wednesday 20 Nov 2024
Divalproex Sodium
CAS:76584-70-8
Divalproex Sodium (Valproate semisodium) binds to and inhibits gamma-aminobutyric acid (GABA) transaminase and its anticonvulsant …
Formula:
C8H16O2·C8H15O2·Na
Purity:
99.84%
Color and Shape:
A White Powder With A Characteristic Odor
Molecular weight:
310.41
Ref: TM-T6474
| 10mg | 39.00 € | ||
| 25mg | 54.00 € | ||
| 50mg | 78.00 € | ||
| 100mg | 114.00 € | ||
| 200mg | 185.00 € | ||
| 500mg | 328.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Wednesday 20 Nov 2024
Cilengitide
CAS:188968-51-6
Cilengitide (EMD 121974) is a potent integrin inhibitor for the αvβ3/5 receptor (IC50: 4.1/79 nM, …
Formula:
C27H40N8O7
Purity:
98% - 99.8%
Color and Shape:
Solid
Molecular weight:
588.66
Ref: TM-T2494
| 1mg | 49.00 € | ||
| 2mg | 69.00 € | ||
| 5mg | 94.00 € | ||
| 10mg | 158.00 € | ||
| 25mg | 268.00 € | ||
| 50mg | 432.00 € | ||
| 100mg | 621.00 € | ||
| 1mL*10mM (DMSO) | 136.00 € |
Estimated delivery in United States, on Wednesday 20 Nov 2024
Tamibarotene
CAS:94497-51-5
Tamibarotene (Amnolake) is an orally active, synthetic retinoid, developed to overcome all-trans retinoic acid (ATRA) …
Formula:
C22H25NO3
Purity:
97.22% - 98.2%
Color and Shape:
Crystalline Solid
Molecular weight:
351.44
Ref: TM-T6694
| 1g | 364.00 € | ||
| 10mg | 46.00 € | ||
| 25mg | 63.00 € | ||
| 50mg | 78.00 € | ||
| 100mg | 95.00 € | ||
| 200mg | 149.00 € | ||
| 500mg | 244.00 € | ||
| 1mL*10mM (DMSO) | 47.00 € |
Estimated delivery in United States, on Wednesday 20 Nov 2024
Chelerythrine
CAS:34316-15-9
1.
Formula:
C21H18NO4
Purity:
98.36%
Color and Shape:
Solid
Molecular weight:
348.37
Ref: TM-T6S0052
| 5mg | 54.00 € | ||
| 10mg | 93.00 € | ||
| 25mg | 140.00 € | ||
| 50mg | 203.00 € | ||
| 100mg | 303.00 € | ||
| 1mL*10mM (DMSO) | 80.00 € |
Estimated delivery in United States, on Wednesday 20 Nov 2024
Licochalcone A
CAS:58749-22-7
Licochalcone A is a flavonoid isolated from the famous Chinese medicinal herb Glycyrrhiza uralensis Fisch …
Formula:
C21H22O4
Purity:
98.11% - 98.96%
Color and Shape:
White Crystalline Powder
Molecular weight:
338.4
Ref: TM-T3600
| 20mg | 97.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Wednesday 20 Nov 2024
N-Benzylpalmitamide
CAS:74058-71-2
N-Benzylpalmitamide (Macamide 1) inhibits fatty acid amide hydrolase (FAAH) in a time-dependent manner and could …
Formula:
C23H39NO
Purity:
99.62% - 99.77%
Color and Shape:
Solid
Molecular weight:
345.56
Ref: TM-T3S2105
| 5mg | 51.00 € | ||
| 10mg | 68.00 € | ||
| 25mg | 101.00 € | ||
| 50mg | 149.00 € | ||
| 100mg | 214.00 € |
Estimated delivery in United States, on Wednesday 20 Nov 2024
Parthenolide
CAS:20554-84-1
Parthenolide ((-)-Parthenolide) is a natural sesquiterpene lactone that is an NF-κB and HDAC1 inhibitor with …
Formula:
C15H20O3
Purity:
99.10% - 99.46%
Color and Shape:
White To Pale Yellow Crystalline Powder
Molecular weight:
248.32
Ref: TM-T2140
| 50mg | 54.00 € | ||
| 100mg | 73.00 € | ||
| 200mg | 115.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Wednesday 20 Nov 2024
Capivasertib
CAS:1143532-39-1
Capivasertib (AZD5363) is a broad-spectrum AKT inhibitor with inhibitory activity against Akt1, Akt2, and Akt3 …
Formula:
C21H25ClN6O2
Purity:
97.59% - 99.6%
Color and Shape:
Solid
Molecular weight:
428.92
Ref: TM-T1920
| 1mg | 40.00 € | ||
| 5mg | 69.00 € | ||
| 10mg | 97.00 € | ||
| 25mg | 165.00 € | ||
| 50mg | 241.00 € | ||
| 100mg | 369.00 € | ||
| 500mg | 1,057.00 € | ||
| 1mL*10mM (DMSO) | 90.00 € |
Estimated delivery in United States, on Wednesday 20 Nov 2024
