Autophagy
Autophagy inhibitors target the cellular process of autophagy, which involves the degradation and recycling of cellular components through lysosomes. Autophagy is a critical mechanism for maintaining cellular homeostasis, but its dysregulation is implicated in various diseases, including cancer, neurodegeneration, and infections. Inhibitors of autophagy can block this process, making them valuable tools for studying the role of autophagy in disease and developing therapeutic strategies. At CymitQuimica, we offer autophagy inhibitors to support your research in cell biology, oncology, and neurodegenerative diseases.
Found 1431 products of "Autophagy"
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Regorafenib monohydrate
CAS:<p>Regorafenib Monohydrate is a novel oral multikinase inhibitor with IC50 values of 13, 4.2, 46, 22, 7, 1.5, 2.5, 28, 19 nM for VEGFR1, murine VEGFR2, murine</p>Formula:C21H17ClF4N4O4Purity:99.69%Color and Shape:SolidMolecular weight:500.83Genipin
CAS:<p>Genipin ((+)-Genipin), an active aglycone derived from an iridoid glycoside called geniposide, is found in the fruit of Gardenia jasminoides Ellis.</p>Formula:C11H14O5Purity:99.09% - 99.21%Color and Shape:SolidMolecular weight:226.23VER-155008
CAS:<p>VER-155008 is a potent Hsp70 family inhibitor with IC50 of 0.5 μM, 2.6 μM, and 2.6 μM in cell-free assays for HSP70, HSC70, and GRP78, respectively.</p>Formula:C25H23Cl2N7O4Purity:97.03% - 99.55%Color and Shape:SolidMolecular weight:556.4Pitavastatin calcium
CAS:Pitavastatin calcium (NK-104), a inhibitor of HMG-CoA reductase, lowers both total cholesterol and low-density lipoprotein cholesterol in animals and humans.Formula:C50H46CaF2N2O8Purity:98.89% - >99.99%Color and Shape:White To Off-White PowderMolecular weight:880.98Tarenflurbil
CAS:<p>Tarenflurbil, the R-enantiomer of flurbiprofen, lacks COX inhibition and was tested for Alzheimer's treatment.</p>Formula:C15H13FO2Purity:98% - 99.9%Color and Shape:SolidMolecular weight:244.26Efavirenz
CAS:Efavirenz (DMP 266) is an HIV-1 inhibitor, affecting reverse transcriptase and various cytochrome P450 enzymes.Formula:C14H9ClF3NO2Purity:99.2% - 99.84%Color and Shape:White To Slightly Pink Crystalline PowderMolecular weight:315.67D4476
CAS:<p>D4476 (Casein Kinase I Inhibitor) is an effective, selective, and cell-permeant CK1 (casein kinase 1) inhibitor( IC50=300 nM in a cell-free assay).</p>Formula:C23H18N4O3Purity:99.7% - 99.96%Color and Shape:SolidMolecular weight:398.41Dactolisib
CAS:<p>Dactolisib (BEZ235) is an orally bioavailable inhibitor of PI3K and mTOR (IC50s: 4 nM/5 nM/7 nM/75 nM, and 20.7 nM for p110α/p110γ/p110δ/p110β and mTOR).</p>Formula:C30H23N5OPurity:97.64% - 99.85%Color and Shape:SolidMolecular weight:469.54Skatole
CAS:Skatole (3-Methyl-1H-indole), produced by bacteria, regulates intestinal epithelial cellular functions through activating aryl hydrocarbon receptors and p38.Formula:C9H9NPurity:99.74%Color and Shape:Leaves From Petroleum Ether; White-Brown Scales SolidMolecular weight:131.17MW-150
CAS:<p>MW-150 (MW01-18-150SRM) is a unique protein kinase inhibitor, is a selective, CNS penetrant, and orally active inhibitor of p38α MAPK with a Ki of 101 nM.</p>Formula:C24H23N5Purity:97.35% - 99.27%Color and Shape:SolidMolecular weight:381.47Lumefantrine
CAS:<p>Lumefantrine, an antimalarial, treats malaria with artemether, effective against Plasmodium spp. including in chloroquine-resistant areas.</p>Formula:C30H32Cl3NOPurity:98.36%Color and Shape:Yellow SolidMolecular weight:528.94Shogaol
CAS:<p>6-Shogaol: anti-inflammatory, analgesic, antipyretic, protects cartilage, arrests cancer cell growth, inhibits metastasis.</p>Formula:C17H24O3Purity:98.26% - 99.93%Color and Shape:SolidMolecular weight:276.37Dapivirine
CAS:<p>Dapivirine (R147681) is a diarylpyrimidine non-nucleoside reverse transcriptase inhibitor.</p>Formula:C20H19N5Purity:98% - 99.77%Color and Shape:SolidMolecular weight:329.4PI-103
CAS:<p>PI-103 is a potent, cell-permeable, ATP-competitive inhibitor of PI3K family members (IC50s: 2/3/3/15/30/23 nM for p110α/β/δ/γ, mTOR, and DNA-PK).</p>Formula:C19H16N4O3Purity:97.79% - 99.3%Color and Shape:SolidMolecular weight:348.36Tezacaftor
CAS:<p>Tezacaftor (VX661) is a small molecule that can be used as a corrector of the cystic fibrosis transmembrane conductance regulator (CFTR) gene function.</p>Formula:C26H27F3N2O6Purity:98.84% - >99.99%Color and Shape:SolidMolecular weight:520.5NS1643
CAS:NS1643 is a potent human ether-a-go-go related gene (hERG) KV11.1 channel activator with EC50 of 10.5 μM.Formula:C15H10F6N2O3Purity:98.37% - 99.31%Color and Shape:SolidMolecular weight:380.24Irinotecan
CAS:<p>Irinotecan (CPT-11), a camptothecin derivative, inhibits topoisomerase I, used for colorectal cancer treatment.</p>Formula:C33H38N4O6Purity:98% - 99.92%Color and Shape:SolidMolecular weight:586.68LY2109761
CAS:<p>LY2109761: a TGF-β dual inhibitor, Ki=38 nM (TβRI) & 300 nM (TβRII), hinders Smad2 phosphorylation.</p>Formula:C26H27N5O2Purity:97% - 99.83%Color and Shape:SolidMolecular weight:441.52trifarotene
CAS:<p>Trifarotene (CD5789) is a RARγ agonist, 65x more selective than RARα and 16x than RARβ, with EC50 of 7.7 nM.</p>Formula:C29H33NO4Purity:99.51%Color and Shape:SolidMolecular weight:459.58Melatonin
CAS:<p>Melatonin (Melatonine) is a natural hormone that activates melatonin receptors. Melatonin regulates the biological clock. Cost-effective and quality-assured.</p>Formula:C13H16N2O2Purity:98% - 99.89%Color and Shape:Pale Yellow Leaflets From Benzene SolidMolecular weight:232.28
