Autophagy
Autophagy inhibitors target the cellular process of autophagy, which involves the degradation and recycling of cellular components through lysosomes. Autophagy is a critical mechanism for maintaining cellular homeostasis, but its dysregulation is implicated in various diseases, including cancer, neurodegeneration, and infections. Inhibitors of autophagy can block this process, making them valuable tools for studying the role of autophagy in disease and developing therapeutic strategies. At CymitQuimica, we offer autophagy inhibitors to support your research in cell biology, oncology, and neurodegenerative diseases.
Found 1430 products of "Autophagy"
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Mavorixafor trihydrochloride
CAS:Mavorixafor trihydrochloride blocks CXCR4 (IC50: 13 nM) and suppresses T-tropic HIV-1 replication (IC50: 1-9 nM). It's orally active.Formula:C21H30Cl3N5Purity:98.00%Color and Shape:SolidMolecular weight:458.86Isradipine
CAS:<p>Isradipine (PN 200-110), a dihydropyridine, is an antihypertensive calcium channel blocker that dilates arteries and reduces resistance.</p>Formula:C19H21N3O5Purity:99.84% - 99.95%Color and Shape:Yellow SolidMolecular weight:371.39Enalaprilat Dihydrate
CAS:<p>Enalaprilat Dihydrate (MK-422 Dihydrate) （IC50=1.94 nM） is a potent angiotensin-converting enzyme (ACE) inhibitor.</p>Formula:C18H24N2O5·2H2OPurity:99.46% - 99.78%Color and Shape:SolidMolecular weight:348.4GNE0877
CAS:<p>GNE0877 (GNE 0877) is a highly effective and specific leucine-rich repeat kinase 2 (LRRK2) inhibitor (Ki: 0.7 nM).</p>Formula:C14H16F3N7Purity:98.01% - 99.97%Color and Shape:SolidMolecular weight:339.32Reversine
CAS:<p>Reversine, a small synthetic purine analogue (2, 6-disubstituted purine), is a potent inhibitior of Aurora A/B/C(IC50s=150-500 nM).</p>Formula:C21H27N7OPurity:98% - 98.42%Color and Shape:SolidMolecular weight:393.49AM580
CAS:<p>AM580 (CD336) is a retinoic acid receptor agonist that is selective for RARα( IC50 : 8 nM )</p>Formula:C22H25NO3Purity:98% - 99.89%Color and Shape:SolidMolecular weight:351.44Bakuchiol
CAS:<p>Bakuchiol: anti-tumor, anti-helminthic, DNA polymerase1 inhibitor, cytotoxic, and anti-bacterial, may prevent dental caries.</p>Formula:C18H24OPurity:98.04% - 99.05%Color and Shape:Brownish Yellow Liquid ViscousMolecular weight:256.38ABT-751
CAS:ABT-751 (E7010) has been investigated for the treatment of Lung Cancer, Non-Small Cell Lung Cancer, and Non-Small-Cell Lung Cancer.Formula:C18H17N3O4SPurity:98.84% - 99.50%Color and Shape:SolidMolecular weight:371.41IKK 16
CAS:IKK 16 (IKK Inhibitor VII) is a selective IκB kinase (IKK) inhibitor for IKK-2, IKK complex and IKK-1 with IC50 of 40 nM, 70 nM and 200 nM, respectively.Formula:C28H29N5OSPurity:98.76% - 99.61%Color and Shape:SolidMolecular weight:483.63Apigenin
CAS:<p>Apigenin (NSC 83244) is an aromatic oil extracted from the flowers or leaves of the daisy-like plants.</p>Formula:C15H10O5Purity:97.64% - 99.66%Color and Shape:Yellow Needles From Aqueous Pyridine SolidMolecular weight:270.24A-867744
CAS:<p>A-867744 is an effective and selective type II positive allosteric modulator of the α7 nAChR (EC50: 1.0 μM).</p>Formula:C20H19ClN2O3SPurity:95.66%Color and Shape:SolidMolecular weight:402.89NL-1
CAS:<p>NL-1 is a mitoNEET inhibitor with antileukemic effect.</p>Formula:C18H25NO3SPurity:98.64%Color and Shape:SolidMolecular weight:335.46Corynoxine
CAS:<p>Corynoxine is a tetracyclic oxindole alkaloid isolated from Uncaria macrophylla.</p>Formula:C22H28N2O4Purity:96.83% - 99.93%Color and Shape:SolidMolecular weight:384.47JH-II-127
CAS:<p>JH-II-127 is an oral LRRK2 inhibitor with IC50s: 6.6 nM (WT), 2.2 nM (G2019S), 47.7 nM (A2016T).</p>Formula:C19H21ClN6O3Purity:98.32%Color and Shape:SolidMolecular weight:416.86CHIR-99021
CAS:<p>View and buy CHIR-99021 from TargetMol.CHIR-99021 is a GSK-3α/β inhibitor.Cited in 10 publications.</p>Formula:C22H18Cl2N8Purity:97.94% - ≥95%Color and Shape:SolidMolecular weight:465.34Ruxolitinib
CAS:<p>Ruxolitinib (INCB018424) is a JAK1/2 inhibitor (IC50=3.3/2.8 nM) that is potent and selective.</p>Formula:C17H18N6Purity:99.4% - >99.99%Color and Shape:SolidMolecular weight:306.36Tozasertib
CAS:<p>Tozasertib (MK-0457) is a pan-Aurora kinase inhibitor (Kis: 0.6/18/4.6 nM for Aurora A/Aurora B/Aurora C).</p>Formula:C23H28N8OSPurity:99.99%Color and Shape:SolidMolecular weight:464.59CFTR corrector 2
CAS:<p>CFTR corrector 2 (FDL169) is a novel and potent CFTR corrector for treating cystic fibrosis (CF) patients who carry the F508del mutation.</p>Formula:C27H23FN4O4Purity:99.66%Color and Shape:SolidMolecular weight:486.49α-Thujone
CAS:<p>α-Thujone is an inhibitor of ACh with an IC50 value of 24.7μM.</p>Formula:C10H16OPurity:97.02% - 98.41%Color and Shape:Less Or Almost Colorless Liquid With A Menthol- Like Odor (Albert-Puleo 1978; Budavari 1996) Colorless Or Almost Colorless Liquid With A Menthol- Like Odor (Albert-Puleo 1978; Budavari 1996)Molecular weight:152.23Urolithin A
CAS:<p>Urolithin A is a metabolite of ellagic acid, which inhibits DNA synthesis and induces apoptosis and autophagy. Cost-effective and quality-assured.</p>Formula:C13H8O4Purity:99.14% - 99.67%Color and Shape:SolidMolecular weight:228.2
