Autophagy
Autophagy inhibitors target the cellular process of autophagy, which involves the degradation and recycling of cellular components through lysosomes. Autophagy is a critical mechanism for maintaining cellular homeostasis, but its dysregulation is implicated in various diseases, including cancer, neurodegeneration, and infections. Inhibitors of autophagy can block this process, making them valuable tools for studying the role of autophagy in disease and developing therapeutic strategies. At CymitQuimica, we offer autophagy inhibitors to support your research in cell biology, oncology, and neurodegenerative diseases.
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Peretinoin
CAS:81485-25-8
Peretinoin (NIK333) is an oral acyclic retinoid with a vitamin A-like structure that targets retinoid …
Formula:
C20H30O2
Purity:
99.86%
Color and Shape:
Solid
Molecular weight:
302.45
Ref: TM-TQ0064
| 1mg | 40.00 € | ||
| 2mg | 51.00 € | ||
| 5mg | 87.00 € | ||
| 10mg | 123.00 € | ||
| 25mg | 227.00 € | ||
| 50mg | 395.00 € | ||
| 100mg | 584.00 € | ||
| 500mg | 1,259.00 € | ||
| 1mL*10mM (DMSO) | 87.00 € |
Estimated delivery in United States, on Monday 16 Dec 2024
LC3-mHTT-IN-AN2
CAS:7758-73-8
LC3-mHTT-IN-AN2 (5,7-Dihydroxy-4-phenylcoumarin) is found in the plant Passiflora serratodigitata with the antibacterial activity.
Formula:
C15H10O4
Purity:
≥98%
Color and Shape:
Solid
Molecular weight:
254.24
Ref: TM-T5070
| 50mg | 48.00 € | ||
| 100mg | 62.00 € | ||
| 1mL*10mM (DMSO) | 49.00 € |
Estimated delivery in United States, on Monday 16 Dec 2024
Rabusertib
CAS:911222-45-2
Rabusertib (IC-83) is a chk1 inhibitor in trials for various cancers, including pancreatic and non-small …
Formula:
C18H22BrN5O3
Purity:
98.86% - 99.63%
Color and Shape:
Solid
Molecular weight:
436.3
Ref: TM-T6084
| 5mg | 45.00 € | ||
| 10mg | 64.00 € | ||
| 25mg | 115.00 € | ||
| 50mg | 172.00 € | ||
| 100mg | 253.00 € | ||
| 200mg | 368.00 € |
Estimated delivery in United States, on Monday 16 Dec 2024
SN-38
CAS:86639-52-3
SN-38 (NK012) is the active metabolite of Irinotecan, a DNA topoisomerase I (Topo I) inhibitor, …
Formula:
C22H20N2O5
Purity:
98% - 99.97%
Color and Shape:
Light-Yellow Solid
Molecular weight:
392.4
Ref: TM-T1703
| 25mg | 51.00 € | ||
| 50mg | 65.00 € | ||
| 100mg | 88.00 € | ||
| 500mg | 150.00 € |
Estimated delivery in United States, on Monday 16 Dec 2024
AS1842856
CAS:836620-48-5
AS1842856 is a Foxo1 inhibitor that blocks the transcriptional activity of Foxo1. AS1842856 has autophagy …
Formula:
C18H22FN3O3
Purity:
100% - 99.56%
Color and Shape:
Solid
Molecular weight:
347.38
Ref: TM-T6762
| 5mg | 51.00 € | ||
| 10mg | 73.00 € | ||
| 25mg | 106.00 € | ||
| 50mg | 149.00 € | ||
| 100mg | 221.00 € | ||
| 200mg | 327.00 € | ||
| 500mg | 553.00 € |
Estimated delivery in United States, on Monday 16 Dec 2024
DMH-1
CAS:1206711-16-1
DMH-1 is a BMP inhibitor that inhibits ALK1, ALK2, ALK3 and ALK6. DMH-1 promotes pluripotent …
Formula:
C24H20N4O
Purity:
98% - 99.92%
Color and Shape:
Solid
Molecular weight:
380.44
Ref: TM-T1942
| 5mg | 62.00 € | ||
| 10mg | 96.00 € | ||
| 25mg | 162.00 € | ||
| 50mg | 277.00 € | ||
| 100mg | 428.00 € | ||
| 500mg | 917.00 € | ||
| 1mL*10mM (DMSO) | 69.00 € |
Estimated delivery in United States, on Monday 16 Dec 2024
SP600125
CAS:129-56-6
SP600125 (JNK Inhibitor II) is a JNK inhibitor that inhibits JNK1, JNK2, and JNK3 (IC50=40/40/90 …
Formula:
C14H8N2O
Purity:
97.63% - 99.58%
Color and Shape:
Solid
Molecular weight:
220.23
Ref: TM-T3109
| 10mg | 48.00 € | ||
| 50mg | 52.00 € | ||
| 100mg | 80.00 € | ||
| 200mg | 90.00 € | ||
| 500mg | 144.00 € |
Estimated delivery in United States, on Monday 16 Dec 2024
Pexmetinib
CAS:945614-12-0
Pexmetinib (ARRY-614) is an orally bioavailable dual p38 MAPK/Tie-2 inhibitor.Cost-effective and quality-assured.
Formula:
C31H33FN6O3
Purity:
98.41% - 99.66%
Color and Shape:
Solid
Molecular weight:
556.63
Ref: TM-T6934
| 2mg | 58.00 € | ||
| 5mg | 95.00 € | ||
| 10mg | 151.00 € | ||
| 25mg | 296.00 € | ||
| 50mg | 501.00 € | ||
| 100mg | 558.00 € | ||
| 1mL*10mM (DMSO) | 119.00 € |
Estimated delivery in United States, on Monday 16 Dec 2024
VPS34 inhibitor 1 (Compound 19, PIK-III analogue)
CAS:1383716-46-8
VPS34 inhibitor 1 (Compound 19, PIK-III analogue) (PIK-III analogue) is a potent and selective inhibitor …
Formula:
C21H25N7O
Purity:
98.60%
Color and Shape:
Solid
Molecular weight:
391.47
Ref: TM-T7944
| 1mg | 66.00 € | ||
| 5mg | 141.00 € | ||
| 10mg | 222.00 € | ||
| 25mg | 389.00 € | ||
| 50mg | 553.00 € | ||
| 100mg | 735.00 € | ||
| 1mL*10mM (DMSO) | 185.00 € |
Estimated delivery in United States, on Monday 16 Dec 2024
Dehydrocorydaline
CAS:30045-16-0
1.
Formula:
C22H24NO4
Purity:
99.84%
Color and Shape:
Solid
Molecular weight:
366.43
Ref: TM-T5S2358
| 1mg | 56.00 € | ||
| 2mg | 80.00 € | ||
| 5mg | 109.00 € | ||
| 10mg | 157.00 € | ||
| 25mg | 257.00 € | ||
| 50mg | 369.00 € | ||
| 100mg | 549.00 € | ||
| 1mL*10mM (DMSO) | 123.00 € |
Estimated delivery in United States, on Monday 16 Dec 2024
PI-1840
CAS:1401223-22-0
PI-1840 is a reversible and selective chymotrypsin-like (CT-L) inhibitor, with little proteasome proteolytic effects on …
Formula:
C22H26N4O3
Purity:
100%
Color and Shape:
Solid
Molecular weight:
394.47
Ref: TM-T6941
| 5mg | 37.00 € | ||
| 10mg | 68.00 € | ||
| 25mg | 114.00 € | ||
| 50mg | 215.00 € | ||
| 100mg | 321.00 € | ||
| 200mg | 459.00 € | ||
| 1mL*10mM (DMSO) | 37.00 € |
Estimated delivery in United States, on Monday 16 Dec 2024
Liensinine
CAS:2586-96-1
1. Liensinine, a kind of isoquinoline alkaloid, can antagonize the ventricular arrhythmias.
Formula:
C37H42N2O6
Purity:
99.56% - 99.93%
Color and Shape:
White-Like Powder
Molecular weight:
610.74
Ref: TM-T5S1099
| 5mg | 51.00 € | ||
| 10mg | 82.00 € | ||
| 25mg | 158.00 € | ||
| 50mg | 245.00 € | ||
| 100mg | 365.00 € |
Estimated delivery in United States, on Monday 16 Dec 2024
Atorvastatin hemicalcium salt
CAS:134523-03-8
Atorvastatin hemicalcium salt (Atorvastatin Calcium) is an orally HMG-CoA reductase inhibitor that lowers cholesterol. Cost-effective …
Formula:
C33H34FN2O5Ca
Purity:
99.662% - 99.89%
Color and Shape:
White Crystalline Powder
Molecular weight:
577.67
Ref: TM-T3116
| 10mg | 49.00 € | ||
| 25mg | 57.00 € | ||
| 50mg | 66.00 € | ||
| 100mg | 97.00 € | ||
| 200mg | 160.00 € | ||
| 500mg | 292.00 € | ||
| 1mL*10mM (DMSO) | 53.00 € |
Estimated delivery in United States, on Monday 16 Dec 2024
CZC-54252
CAS:1191911-27-9
CZC-54252 is a potent inhibitor of LRRK2.
Formula:
C22H25ClN6O4S
Purity:
99.39%
Color and Shape:
Solid
Molecular weight:
504.99
Ref: TM-T2022
| 1mg | 38.00 € | ||
| 2mg | 49.00 € | ||
| 5mg | 80.00 € | ||
| 10mg | 116.00 € | ||
| 25mg | 215.00 € | ||
| 50mg | 323.00 € | ||
| 1mL*10mM (DMSO) | 89.00 € |
Estimated delivery in United States, on Monday 16 Dec 2024
Nilotinib monohydrochloride monohydrate
CAS:923288-90-8
Nilotinib monohydrochloride monohydrate (Nilotinib (monohydrochloride monohydrate)) is significantly potent BCR-ABL against, is a second generation …
Formula:
C28H22F3N7O·HCl·H2O
Purity:
99.93%
Color and Shape:
Solid
Molecular weight:
583.99
Ref: TM-T2147
| 50mg | 39.00 € | ||
| 100mg | 51.00 € | ||
| 200mg | 64.00 € | ||
| 500mg | 114.00 € | ||
| 1mL*10mM (DMSO) | 36.00 € |
Estimated delivery in United States, on Monday 16 Dec 2024
Autogramin-2
CAS:2375541-45-8
Autogramin-2 (tert-butyl 2-(4-isopropoxybenzamido)-6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-carboxylate) potently inhibits autophagy induced by either
Formula:
C21H27N3O4S
Purity:
96.25%
Color and Shape:
Solid
Molecular weight:
417.52
Ref: TM-T9013
| 5mg | 44.00 € | ||
| 10mg | 63.00 € | ||
| 25mg | 107.00 € | ||
| 50mg | 169.00 € | ||
| 100mg | 255.00 € | ||
| 200mg | 359.00 € | ||
| 1mL*10mM (DMSO) | 50.00 € |
Estimated delivery in United States, on Monday 16 Dec 2024
Vismodegib
CAS:879085-55-9
Vismodegib (GDC-0449) is a hedgehog pathway inhibitor (IC50: 3 nM). It also inhibits P-gp (IC50: …
Formula:
C19H14Cl2N2O3S
Purity:
98% - 99.99%
Color and Shape:
Solid
Molecular weight:
421.3
Ref: TM-T2590
| 5mg | 45.00 € | ||
| 10mg | 57.00 € | ||
| 50mg | 72.00 € | ||
| 100mg | 92.00 € | ||
| 200mg | 106.00 € | ||
| 1mL*10mM (DMSO) | 63.00 € |
Estimated delivery in United States, on Monday 16 Dec 2024
PFK-158
CAS:1462249-75-7
PFK-158 is an effective and specific inhibitor PFKFB3.
Formula:
C18H11F3N2O
Purity:
95.49% - 98.58%
Color and Shape:
Solid
Molecular weight:
328.29
Ref: TM-T3105
| 1mg | 35.00 € | ||
| 2mg | 47.00 € | ||
| 5mg | 69.00 € | ||
| 10mg | 94.00 € | ||
| 25mg | 171.00 € | ||
| 50mg | 269.00 € | ||
| 100mg | 423.00 € | ||
| 1mL*10mM (DMSO) | 77.00 € |
Estimated delivery in United States, on Monday 16 Dec 2024
Trametinib
CAS:871700-17-3
Trametinib (GSK1120212), an ATP-noncompetitive MEK 1/2 inhibitor (IC50: 0.7/0.9 nM), weakly inhibits >180 kinases.
Formula:
C26H23FIN5O4
Purity:
98% - 99.88%
Color and Shape:
Solid
Molecular weight:
615.39
Ref: TM-T2125
| 5mg | 36.00 € | ||
| 10mg | 54.00 € | ||
| 50mg | 69.00 € | ||
| 100mg | 96.00 € | ||
| 200mg | 135.00 € | ||
| 1mL*10mM (DMSO) | 54.00 € |
Estimated delivery in United States, on Monday 16 Dec 2024
Levosimendan
CAS:141505-33-1
Levosimendan (OR1259) is a calcium sensitizer for acute heart failure, enhancing cardiac contractility without raising …
Formula:
C14H12N6O
Purity:
99.32% - 99.91%
Color and Shape:
Yellow Crystalline Powder
Molecular weight:
280.28
Ref: TM-T2530
| 25mg | 37.00 € | ||
| 50mg | 49.00 € | ||
| 100mg | 66.00 € | ||
| 200mg | 100.00 € | ||
| 500mg | 221.00 € |
Estimated delivery in United States, on Monday 16 Dec 2024
