Autophagy
Autophagy inhibitors target the cellular process of autophagy, which involves the degradation and recycling of cellular components through lysosomes. Autophagy is a critical mechanism for maintaining cellular homeostasis, but its dysregulation is implicated in various diseases, including cancer, neurodegeneration, and infections. Inhibitors of autophagy can block this process, making them valuable tools for studying the role of autophagy in disease and developing therapeutic strategies. At CymitQuimica, we offer autophagy inhibitors to support your research in cell biology, oncology, and neurodegenerative diseases.
Found 1430 products of "Autophagy"
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ZLN005
CAS:<p>ZLN005 is an effective and tissue-specific transcriptional activator of PGC-1α.</p>Formula:C17H18N2Purity:98.59% - >99.99%Color and Shape:SolidMolecular weight:250.34TWS119
CAS:<p>TWS119 is a GSK-3β inhibitor; capable of inducing neuronal differentiation</p>Formula:C18H14N4O2Purity:98.14% - 99.63%Color and Shape:SolidMolecular weight:318.33Rutin hydrate
CAS:<p>Rutin hydrate (Sophorin), a kind of glycoside, widely exists in many plants including citrus fruit.</p>Formula:C27H32O17Purity:97.23%Color and Shape:SolidMolecular weight:628.53Liensinine diperchlorate
CAS:<p>Liensinine Diperchlorate is an isoquinoline alkaloid extracted from the embryonic seeds of the sacred lotus.</p>Formula:C37H44Cl2N2O14Purity:99.8% - ≥95%Color and Shape:SolidMolecular weight:811.67Entrectinib
CAS:<p>Entrectinib (RXDX-101) is an orally Trk, ROS1, and ALK inhibitor. Entrectinib exhibits antitumor activity. Cost-effective and quality-assured.</p>Formula:C31H34F2N6O2Purity:98.03% - 99.61%Color and Shape:SolidMolecular weight:560.64Quercetin
CAS:<p>Quercetin (Sophoretin) is a natural flavonoid and is an agonist of SIRT1.</p>Formula:C15H10O7Purity:96.29% - 98.05%Color and Shape:Sensitive To Exposure To Air And Light Insoluble In Water Alcoholic Solutions Taste Very Bitter (Ntp 1992)Molecular weight:302.24Bafilomycin A1
CAS:<p>Bafilomycin A1 belongs to the macrolide class of antibiotics and is a V-ATPase (IC50=0.44 nM) that is specific and reversible.</p>Formula:C35H58O9Purity:95.87% - 99.36%Color and Shape:SolidMolecular weight:622.83Dronedarone
CAS:<p>Dronedarone (SR 33589) is an amiodarone analogue which has an effective and promising treatment for Atrial fibrillation.</p>Formula:C31H44N2O5SPurity:98.85% - 99.58%Color and Shape:SolidMolecular weight:556.76PF-04457845
CAS:<p>PF-04457845 is a greatly and effctive FAAH inhibitor, and for hFAAH(IC50=7.2±0.63 nM) and rFAAH(IC50=7.4±0.62 nM).</p>Formula:C23H20F3N5O2Purity:>99.99%Color and Shape:SolidMolecular weight:455.43MRT68921
CAS:<p>MRT68921 is a potent and dual autophagy kinase ULK1/2 inhibitor with IC50 of 2.9 nM and 1.1 nM, respectively.</p>Formula:C25H34N6OPurity:99.23%Color and Shape:SolidMolecular weight:434.58KU-55933
CAS:<p>KU-55933 (ATM Kinase Inhibitor) is an ATM inhibitor that is selective and ATP-competitive. KU-55933 has antitumor effects. Cost-effective and quality-assured.</p>Formula:C21H17NO3S2Purity:97.21% - >99.99%Color and Shape:SolidMolecular weight:395.49CGI-1746
CAS:<p>CGI1746 is a potent and highly selective small-molecule Btk inhibitor with IC50 of 1.9 nM.</p>Formula:C34H37N5O4Purity:97.69% - 97.88%Color and Shape:SolidMolecular weight:579.69Tolvaptan
CAS:<p>Tolvaptan (OPC-41061) is an orally bioavailable, selective, arginine vasopressin receptor 2 (V2, AVPR2) antagonist that can be used to treat hyponatremia.</p>Formula:C26H25ClN2O3Purity:99.78% - >99.99%Color and Shape:SolidMolecular weight:448.94Telaglenastat hydrochloride
CAS:<p>Telaglenastat (CB-839) HCl: First-in-class, oral GLS1 inhibitor, targets KGA/GAC, IC50 23-28 nM, triggers autophagy, anticancer.</p>Formula:C26H25ClF3N7O3SColor and Shape:SolidMolecular weight:608.04Belinostat
CAS:Belinostat (PXD101) is an inhibitor of hydroxamic acid-type histone deacetylase (HDAC, IC50 of 27 nM in HeLa cell extracts),and with antineoplastic activity.Formula:C15H14N2O4SPurity:99.75% - >99.99%Color and Shape:SolidMolecular weight:318.35Quisinostat
CAS:Quisinostat (JNJ-26481585), a second-gen HDAC inhibitor, is most potent for HDAC1 (IC50 0.11 nM) and selectively affects HDACs 2, 4, 10, and 11.Formula:C21H26N6O2Purity:96.01% - ≥98%Color and Shape:SolidMolecular weight:394.47SBE13
CAS:<p>SBE13 is a selective and potent inhibitor of Plk1 (IC50: 200 pM). SBE13 has a weak effect on Plk2 or Plk3 with IC50 values of >66 μM and 875 nM respectively.</p>Formula:C24H27ClN2O4Color and Shape:SolidMolecular weight:442.94Biochanin A
CAS:<p>Biochanin A: an isoflavone from red clover with anticancer properties and inhibits FAAH.</p>Formula:C16H12O5Purity:97.1% - 98.97%Color and Shape:SolidMolecular weight:284.26Isodeoxyelephantopin
CAS:<p>Isodeoxyelephantopin can inhibit the growth of various tumor cells.</p>Formula:C19H20O6Purity:99.88%Color and Shape:SolidMolecular weight:344.36Nur77 modulator 1
CAS:<p>Nur77 modulator 1: binds at 3.58 μM, boosts expression, alters location, triggers ER stress/autophagy, induces apoptosis, and fights hepatoma.</p>Formula:C28H25N5O2SPurity:99.62%Color and Shape:SolidMolecular weight:495.6
