Autophagy
Autophagy inhibitors target the cellular process of autophagy, which involves the degradation and recycling of cellular components through lysosomes. Autophagy is a critical mechanism for maintaining cellular homeostasis, but its dysregulation is implicated in various diseases, including cancer, neurodegeneration, and infections. Inhibitors of autophagy can block this process, making them valuable tools for studying the role of autophagy in disease and developing therapeutic strategies. At CymitQuimica, we offer autophagy inhibitors to support your research in cell biology, oncology, and neurodegenerative diseases.
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Obatoclax Mesylate
CAS:803712-79-0
Obatoclax Mesylate (GX15-070) is a Bcl-2 antagonist (Ki: 0.22 μM) and can induce apoptosis with …
Formula:
C20H19N3O·CH4O3S
Purity:
99.67% - 99.88%
Color and Shape:
Solid
Molecular weight:
413.49
Ref: TM-T6275
| 5mg | 50.00 € | ||
| 10mg | 73.00 € | ||
| 25mg | 122.00 € | ||
| 50mg | 209.00 € | ||
| 100mg | 351.00 € | ||
| 1mL*10mM (DMSO) | 53.00 € |
Estimated delivery in United States, on Thursday 12 Dec 2024
Chloroquine
CAS:54-05-7
Chloroquine: antimalarial, anti-inflammatory, autophagy/TLRs inhibitor, treats arthritis, effective against COVID-19 in vitro. EC50: 1.13 μM.
Formula:
C18H26ClN3
Purity:
99.94% - ≥98%
Color and Shape:
White To Slightly Yellow Crystalline Powder Solid
Molecular weight:
319.87
Ref: TM-T8689
| 100mg | 57.00 € | ||
| 200mg | 89.00 € | ||
| 500mg | 172.00 € | ||
| 1mL*10mM (DMSO) | 53.00 € |
Estimated delivery in United States, on Thursday 12 Dec 2024
A-484954
CAS:142557-61-7
A-484954 (A 484954) is a highly specific eukaryotic elongation factor-2 (eEF2, IC50: 280 nM) inhibitor.
Formula:
C13H15N5O3
Purity:
97.47%
Color and Shape:
Solid
Molecular weight:
289.29
Ref: TM-TQ0137
| 1mg | 42.00 € | ||
| 2mg | 60.00 € | ||
| 5mg | 91.00 € | ||
| 10mg | 148.00 € | ||
| 25mg | 306.00 € | ||
| 50mg | 536.00 € | ||
| 100mg | 762.00 € | ||
| 1mL*10mM (DMSO) | 103.00 € |
Estimated delivery in United States, on Thursday 12 Dec 2024
Salvigenin
CAS:19103-54-9
Salvigenin is a potent hMAO-A inhibitor, has neuroprotective, antitumor and immunomodulatory effects.
Formula:
C18H16O6
Purity:
99.17% - 99.67%
Color and Shape:
Solid
Molecular weight:
328.32
Ref: TM-TMS1743
| 1mg | 70.00 € | ||
| 5mg | 153.00 € | ||
| 10mg | 245.00 € | ||
| 25mg | 418.00 € | ||
| 50mg | 600.00 € | ||
| 1mL*10mM (DMSO) | 168.00 € |
Estimated delivery in United States, on Thursday 12 Dec 2024
Leonurine
CAS:24697-74-3
Leonurine (SCM-198) is an alkaloid that has been found in H. leonuri and with anti-oxidative …
Formula:
C14H21N3O5
Purity:
98.55%
Color and Shape:
White Crystalline Powder
Molecular weight:
311.33
Ref: TM-T5S2102
| 5mg | 36.00 € | ||
| 10mg | 52.00 € | ||
| 25mg | 94.00 € | ||
| 50mg | 141.00 € | ||
| 100mg | 200.00 € | ||
| 500mg | 497.00 € |
Estimated delivery in United States, on Thursday 12 Dec 2024
Losmapimod
CAS:585543-15-3
Losmapimod (GSK-AHAB) (GW856553X; SB856553; GSK-AHAB) is a specific, potent, and orally active p38 MAPK inhibitor …
Formula:
C22H26FN3O2
Purity:
98.56% - 99.05%
Color and Shape:
Solid
Molecular weight:
383.46
Ref: TM-T2277
| 2mg | 35.00 € | ||
| 5mg | 52.00 € | ||
| 10mg | 77.00 € | ||
| 25mg | 137.00 € | ||
| 50mg | 222.00 € | ||
| 100mg | 398.00 € | ||
| 500mg | 906.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Thursday 12 Dec 2024
Indophagolin
CAS:1207660-00-1
Indophagolin: autophagy inhibitor, IC50 140 nM; blocks P2X4, P2X1, P2X3 receptors, IC50s 2.71, 2.40, 3.49 …
Formula:
C19H15BrClF3N2O3S
Purity:
99.76%
Color and Shape:
Solid
Molecular weight:
523.75
Ref: TM-T8946
| 1mg | 56.00 € | ||
| 5mg | 108.00 € | ||
| 10mg | 169.00 € | ||
| 25mg | 273.00 € | ||
| 50mg | 379.00 € | ||
| 100mg | 533.00 € | ||
| 200mg | 722.00 € | ||
| 1mL*10mM (DMSO) | 125.00 € |
Estimated delivery in United States, on Thursday 12 Dec 2024
Pamapimod
CAS:449811-01-2
Pamapimod (R1503) (R-1503, Ro4402257) is a novel, selective inhibitor of p38 mitogen-activated protein kinase.
Formula:
C19H20F2N4O4
Purity:
97.63% - 99.99%
Color and Shape:
Solid
Molecular weight:
406.38
Ref: TM-T6927
| 1mg | 55.00 € | ||
| 5mg | 118.00 € | ||
| 10mg | 183.00 € | ||
| 25mg | 369.00 € | ||
| 50mg | 595.00 € | ||
| 100mg | 833.00 € | ||
| 500mg | 1,672.00 € | ||
| 1mL*10mM (DMSO) | 130.00 € |
Estimated delivery in United States, on Thursday 12 Dec 2024
BIX-01294 trihydrochloride
CAS:1392399-03-9
BIX-01294 trihydrochloride is an inhibitor of G9a histone methyltransferase.In a cell-free assay, the IC50=2.7 μM …
Formula:
C28H38N6O2·3HCl
Purity:
98.98% - 99.95%
Color and Shape:
Solid
Molecular weight:
600.02
Ref: TM-T1959
| 1mg | 43.00 € | ||
| 2mg | 55.00 € | ||
| 5mg | 72.00 € | ||
| 10mg | 108.00 € | ||
| 25mg | 192.00 € | ||
| 50mg | 274.00 € | ||
| 100mg | 493.00 € | ||
| 500mg | 1,084.00 € | ||
| 1mL*10mM (DMSO) | 140.00 € |
Estimated delivery in United States, on Thursday 12 Dec 2024
CCT007093
CAS:176957-55-4
CCT007093 is an effective PPM1D (WIP1) inhibitor (IC50: 8.4 μM).
Formula:
C15H12OS2
Purity:
98% - 99.75%
Color and Shape:
Solid
Molecular weight:
272.39
Ref: TM-T1927
| 5mg | 46.00 € | ||
| 10mg | 71.00 € | ||
| 25mg | 121.00 € | ||
| 50mg | 212.00 € | ||
| 100mg | 369.00 € | ||
| 500mg | 1,003.00 € |
Estimated delivery in United States, on Thursday 12 Dec 2024
Salubrinal
CAS:405060-95-9
Salubrinal, a phosphatases (PP1) inhibitor(IC50=1.7 μM), exhibits function on the eukaryotic translation initiation factor 2 …
Formula:
C21H17Cl3N4OS
Purity:
100% - 98.25%
Color and Shape:
Solid
Molecular weight:
479.81
Ref: TM-T3045
| 2mg | 41.00 € | ||
| 5mg | 61.00 € | ||
| 10mg | 91.00 € | ||
| 25mg | 160.00 € | ||
| 50mg | 268.00 € | ||
| 100mg | 455.00 € | ||
| 500mg | 1,012.00 € | ||
| 1mL*10mM (DMSO) | 68.00 € |
Estimated delivery in United States, on Thursday 12 Dec 2024
Vacuolin-1
CAS:351986-85-1
Vacuolin-1 is a cell-permeable inhibitor of Ca2+ dependent fusion of lysosomes to the cell membrane.
Formula:
C26H24IN7O
Purity:
98.45% - 99.45%
Color and Shape:
Solid
Molecular weight:
577.42
Ref: TM-T21992
| 1mg | 37.00 € | ||
| 5mg | 78.00 € | ||
| 10mg | 109.00 € | ||
| 25mg | 203.00 € | ||
| 50mg | 341.00 € | ||
| 100mg | 530.00 € |
Estimated delivery in United States, on Thursday 12 Dec 2024
Nobiletin
CAS:478-01-3
Nobiletin: a citrus-derived flavone with anti-inflammatory and anti-cancer properties; water-insoluble, very weak acid.
Formula:
C21H22O8
Purity:
98.78% - 98.88%
Color and Shape:
Solid
Molecular weight:
402.39
Ref: TM-T2834
| 5mg | 56.00 € | ||
| 10mg | 87.00 € | ||
| 25mg | 121.00 € | ||
| 50mg | 165.00 € | ||
| 100mg | 259.00 € | ||
| 200mg | 384.00 € | ||
| 500mg | 639.00 € | ||
| 1mL*10mM (DMSO) | 59.00 € |
Estimated delivery in United States, on Thursday 12 Dec 2024
Lonafarnib
CAS:193275-84-2
Lonafarnib (Sch66336) is an orally bioavailable FPTase inhibitor for H-ras, K-ras-4B, and N-ras (IC50: 1.9/5.2/2.8 …
Formula:
C27H31Br2ClN4O2
Purity:
98% - 99.04%
Color and Shape:
Solid
Molecular weight:
638.82
Ref: TM-T6302
| 1mg | 48.00 € | ||
| 5mg | 94.00 € | ||
| 10mg | 149.00 € | ||
| 25mg | 292.00 € | ||
| 50mg | 462.00 € | ||
| 100mg | 646.00 € | ||
| 1mL*5mM (DMSO) | 164.00 € |
Estimated delivery in United States, on Thursday 12 Dec 2024
Pyriproxyfen
CAS:95737-68-1
Pyriproxyfen (S-31183) is an insecticide that acts as a biomimetic of juvenile hormone.
Formula:
C20H19NO3
Purity:
98.14%
Color and Shape:
Solid Compact
Molecular weight:
321.37
Ref: TM-T16696
| 1g | 35.00 € | ||
| 5g | 63.00 € | ||
| 10g | 90.00 € | ||
| 1mL*10mM (DMSO) | 35.00 € |
Estimated delivery in United States, on Thursday 12 Dec 2024
Enzastaurin
CAS:170364-57-5
Enzastaurin (LY317615) (LY317615) is an effective PKCβ selective inhibitor (IC50: 6 nM), 6- to 20-fold …
Formula:
C32H29N5O2
Purity:
100% - 99.24%
Color and Shape:
Solid
Molecular weight:
515.6
Ref: TM-T6280
| 5mg | 50.00 € | ||
| 10mg | 66.00 € | ||
| 25mg | 95.00 € | ||
| 50mg | 121.00 € | ||
| 100mg | 184.00 € | ||
| 1mL*10mM (DMSO) | 53.00 € |
Estimated delivery in United States, on Thursday 12 Dec 2024
UNC0638
CAS:1255580-76-7
UNC0638 inhibits G9a and GLP lysine methyltransferases with IC50 <15 nM and 19 nM, respectively, …
Formula:
C30H47N5O2
Purity:
99.53%
Color and Shape:
Solid
Molecular weight:
509.73
Ref: TM-T3257
| 5mg | 59.00 € | ||
| 10mg | 88.00 € | ||
| 25mg | 143.00 € | ||
| 50mg | 252.00 € | ||
| 100mg | 382.00 € | ||
| 1mL*10mM (DMSO) | 65.00 € |
Estimated delivery in United States, on Thursday 12 Dec 2024
CA-5f
CAS:1370032-19-1
CA-5f is a potent late-stage macroautophagy/autophagy inhibitor via inhibiting autophagosome-lysosome fusion.
Formula:
C24H24N2O3
Purity:
99.83%
Color and Shape:
Solid
Molecular weight:
388.46
Ref: TM-T5181
| 1mg | 47.00 € | ||
| 5mg | 87.00 € | ||
| 10mg | 143.00 € | ||
| 25mg | 259.00 € | ||
| 50mg | 419.00 € | ||
| 100mg | 647.00 € | ||
| 1mL*10mM (DMSO) | 96.00 € |
Estimated delivery in United States, on Thursday 12 Dec 2024
Genistein
CAS:446-72-0
Genistein (NPI 031L) is a natural soy isoflavone, a multi-targeted tyrosine kinase inhibitor. Genistein has …
Formula:
C15H10O5
Purity:
98.22% - 99.69%
Color and Shape:
Rectangular Or Six-Sided Rods From 60% Alcohol Dendritic Needles From Ether Solid
Molecular weight:
270.24
Ref: TM-T1737
| 50mg | 45.00 € | ||
| 100mg | 58.00 € | ||
| 500mg | 93.00 € | ||
| 1mL*10mM (DMSO) | 63.00 € |
Estimated delivery in United States, on Thursday 12 Dec 2024
(1E,6E)-Bis(demethoxy)curcumin
CAS:33171-05-0
(1E,6E)-Bis(demethoxy)curcumin (Curcumin III) is a natural demethoxy derivative of curcumin,with anti-inflammatory and anti-cancer activities.
Formula:
C19H16O4
Purity:
97.45%
Color and Shape:
Solid
Molecular weight:
308.33
Ref: TM-T6S1688
| 20mg | 76.00 € |
Estimated delivery in United States, on Thursday 12 Dec 2024
