Autophagy
Autophagy inhibitors target the cellular process of autophagy, which involves the degradation and recycling of cellular components through lysosomes. Autophagy is a critical mechanism for maintaining cellular homeostasis, but its dysregulation is implicated in various diseases, including cancer, neurodegeneration, and infections. Inhibitors of autophagy can block this process, making them valuable tools for studying the role of autophagy in disease and developing therapeutic strategies. At CymitQuimica, we offer autophagy inhibitors to support your research in cell biology, oncology, and neurodegenerative diseases.
Found 1431 products of "Autophagy"
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Nur77 modulator 1
CAS:<p>Nur77 modulator 1: binds at 3.58 μM, boosts expression, alters location, triggers ER stress/autophagy, induces apoptosis, and fights hepatoma.</p>Formula:C28H25N5O2SPurity:99.62%Color and Shape:SolidMolecular weight:495.6KM11060
CAS:<p>KM11060 is a novel corrector of the F508del-CFTR trafficking defect, Correcting F508del-CFTR trafficking, increasing the amount of functional CFTR at the plasma</p>Formula:C19H17Cl2N3O2SPurity:98.86%Color and Shape:SolidMolecular weight:422.33Pirarubicin HCl
CAS:<p>Pirarubicin HCl, a less cardiotoxic doxorubicin analogue, hinders DNA replication and repairs by intercalating into DNA and inhibiting topoisomerase II.</p>Formula:C32H38ClNO12Color and Shape:SolidMolecular weight:664.1Fasudil hydrochloride
CAS:<p>Fasudil hydrochloride (HA-1077) is a potent inhibitor of ROCK1, PKA, PKC, and MLCK with Ki of 0.33 μM, 1.0 μM, 9.3 μM and 55 μM, respectively.</p>Formula:C14H18ClN3O2SPurity:99.54% - ≥95%Color and Shape:White SolidMolecular weight:327.83Veliparib
CAS:<p>Veliparib (ABT-888) (ABT-888) is an orally bioavailable inhibitor of PARP (Kis: 5.2/2.9 nM for PARP1/2). It enhances apoptosis and autophagy.</p>Formula:C13H16N4OPurity:98.66% - 99%Color and Shape:SolidMolecular weight:244.29Crenolanib
CAS:<p>Crenolanib (ARO 002) is an orally bioavailable type III tyrosine kinases inhibitor of PDGFRα/β and FLT3 (IC50s: 11, 3.2, and 4 nM).</p>Formula:C26H29N5O2Purity:98.40% - 99.73%Color and Shape:SolidMolecular weight:443.54NUCC-390 dihydrochloride
CAS:<p>NUCC-390, a selective CXCR4 agonist, promotes nerve repair by inducing CXCR4 internalization, opposite to AMD3100.</p>Formula:C23H35Cl2N5OColor and Shape:SolidMolecular weight:468.46Regorafenib
CAS:<p>Regorafenib (BAY 73-4506) is a multi-targeted receptor tyrosine kinase inhibitor that inhibits RET, C-RAF, VEGFR2, c-Kit, VEGFR1, and PDGFRβ and is orally</p>Formula:C21H15ClF4N4O3Purity:98% - 99.95%Color and Shape:SolidMolecular weight:482.82Torin 2
CAS:<p>Torin 2: mTOR inhibitor, IC50=0.25 nM, 800x more selective than PI3K, with EC50=28/35/118 nM for ATM/ATR/DNA-PK.</p>Formula:C24H15F3N4OPurity:98.31% - 99.32%Color and Shape:SolidMolecular weight:432.4Nordihydroguaiaretic acid
CAS:<p>Nordihydroguaiaretic acid (NDGA) is a natural lipoxygenase (5-LOX) inhibitor. Nordihydroguaiaretic acid has antioxidant effect. Cost-effective and quality-assured.</p>Formula:C18H22O4Purity:97.82% - 99.91%Color and Shape:SolidMolecular weight:302.36Venetoclax
CAS:<p>Venetoclax (ABT-199) is a selective inhibitor of Bcl-2 (Ki < 0.010 nM), binding over 3 orders of magnitude less avidly to Bcl-xL, and Bcl-W (Kis = 48/245 nM).</p>Formula:C45H50ClN7O7SPurity:98.00% - 99.97%Color and Shape:SolidMolecular weight:868.44Genistein
CAS:<p>Genistein (NPI 031L) is a natural soy isoflavone, a multi-targeted tyrosine kinase inhibitor. Genistein has antitumor effects. Cost effective and quality assured.</p>Formula:C15H10O5Purity:98.22% - 99.64%Color and Shape:Rectangular Or Six-Sided Rods From 60% Alcohol Dendritic Needles From Ether SolidMolecular weight:270.24EIPA
CAS:<p>EIPA (L593754) is a TRPP3 channel inhibitor and an inhibitor of Na+/H+ exchange (NHE). EIPA inhibits megacytosis, promotes autophagy. Cost-effective and quality-assured.</p>Formula:C11H18ClN7OPurity:96.62% - 99.981%Color and Shape:Off-White To Yellow SolidMolecular weight:299.76(1E,6E)-Bis(demethoxy)curcumin
CAS:<p>(1E,6E)-Bis(demethoxy)curcumin (Curcumin III) is a natural demethoxy derivative of curcumin,with anti-inflammatory and anti-cancer activities.</p>Formula:C19H16O4Purity:97.45%Color and Shape:SolidMolecular weight:308.33AG490
CAS:AG490 inhibits EGFR (0.1 μM IC50), 135x > selective than ErbB2, blocks JAK2, spares Lyn, Lck, Syk, Btk, Src.Formula:C17H14N2O3Purity:98.6% - 99.85%Color and Shape:Yellow SolidMolecular weight:294.3PD146176
CAS:<p>PD146176 (NSC-168807) is an inhibitor of 15-Lipoxygenase (15-LO) , it inhibits rabbit reticulocyte 15-LO with Ki of 197 nM and IC50 of 0.54 μM.</p>Formula:C15H11NSPurity:98.00%Color and Shape:SolidMolecular weight:237.32Troglitazone
CAS:<p>Troglitazone (Romglizone) is a PPARγ agonist with anti-inflammatory and anti-tumor activity.</p>Formula:C24H27NO5SPurity:98% - 99.8%Color and Shape:Yellow SolidMolecular weight:441.54Lumacaftor
CAS:<p>Lumacaftor (VRT 826809) is a CFTR modulator that corrects the folding and trafficking of CFTR protein.</p>Formula:C24H18F2N2O5Purity:99.48% - 99.68%Color and Shape:SolidMolecular weight:452.41Tomatidine
CAS:<p>Tomatidine serves as an anti-inflammatory agent by inhibiting NF-κB and JNK signaling pathways.</p>Formula:C27H45NO2Purity:99.94% - 99.98%Color and Shape:SolidMolecular weight:415.65Glyphosate
CAS:<p>Glyphosate (Atila) is an herbicide. It also is a possible carcinogen to humans.</p>Formula:C3H8NO5PPurity:99.12% - 99.91%Color and Shape:White Crystals (Darkens) Ph (1% Solution In Water) 2 5 (Ntp 1992)Molecular weight:169.07
