Autophagy
Autophagy inhibitors target the cellular process of autophagy, which involves the degradation and recycling of cellular components through lysosomes. Autophagy is a critical mechanism for maintaining cellular homeostasis, but its dysregulation is implicated in various diseases, including cancer, neurodegeneration, and infections. Inhibitors of autophagy can block this process, making them valuable tools for studying the role of autophagy in disease and developing therapeutic strategies. At CymitQuimica, we offer autophagy inhibitors to support your research in cell biology, oncology, and neurodegenerative diseases.
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Rosuvastatin
CAS:287714-41-4
Rosuvastatin (ZD4522) is an inhibitor of HMG-CoA reductase (HMGCR). Rosuvastatin has hypolipidemic and antiatherosclerotic effects. …
Formula:
C22H28FN3O6S
Purity:
95.24% - 99.8%
Color and Shape:
Solid
Molecular weight:
481.54
Ref: TM-T1676
| 5mg | 49.00 € | ||
| 10mg | 79.00 € | ||
| 25mg | 121.00 € | ||
| 50mg | 163.00 € | ||
| 100mg | 259.00 € | ||
| 200mg | 363.00 € |
Estimated delivery in United States, on Wednesday 20 Nov 2024
STF-31
CAS:724741-75-7
STF-31 is an inhibitor of glucose transporter 1 (GLUT1) with IC50 of 1 μM.
Formula:
C23H25N3O3S
Purity:
99.55% - 99.98%
Color and Shape:
Solid
Molecular weight:
423.53
Ref: TM-T2363
| 1mg | 38.00 € | ||
| 2mg | 50.00 € | ||
| 5mg | 80.00 € | ||
| 10mg | 111.00 € | ||
| 25mg | 227.00 € | ||
| 50mg | 426.00 € | ||
| 100mg | 625.00 € | ||
| 500mg | 1,324.00 € | ||
| 1mL*10mM (DMSO) | 106.00 € |
Estimated delivery in United States, on Wednesday 20 Nov 2024
Dehydrocorydaline
CAS:30045-16-0
1.
Formula:
C22H24NO4
Purity:
99.84%
Color and Shape:
Solid
Molecular weight:
366.43
Ref: TM-T5S2358
| 1mg | 56.00 € | ||
| 2mg | 80.00 € | ||
| 5mg | 109.00 € | ||
| 10mg | 157.00 € | ||
| 25mg | 257.00 € | ||
| 50mg | 369.00 € | ||
| 100mg | 549.00 € | ||
| 1mL*10mM (DMSO) | 123.00 € |
Estimated delivery in United States, on Wednesday 20 Nov 2024
Atorvastatin
CAS:134523-00-5
Orally active atorvastatin inhibits HMG-CoA reductase, lowers lipids, hinders SV-SMC cell growth, and can up …
Formula:
C33H35FN2O5
Purity:
99.69%
Color and Shape:
Solid
Molecular weight:
558.64
Ref: TM-T20765
| 2mg | 34.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
MK-5108
CAS:1010085-13-8
MK-5108 (VX-689) is a highly potent and specific Aurora-A kinase inhibitor with an IC50 value …
Formula:
C22H21ClFN3O3S
Purity:
100%
Color and Shape:
Solid
Molecular weight:
461.94
Ref: TM-T6068
| 1mg | 40.00 € | ||
| 5mg | 86.00 € | ||
| 10mg | 134.00 € | ||
| 25mg | 222.00 € | ||
| 50mg | 346.00 € | ||
| 100mg | 517.00 € | ||
| 1mL*10mM (DMSO) | 90.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
Dehydrocorydaline nitrate
CAS:13005-09-9
DHC curbs antibody and cell-mediated allergies, inhibits mitochondrial potential in macrophages, and has antinociceptive, anti-inflammatory …
Formula:
C22H24N2O7
Purity:
99.79%
Color and Shape:
Solid
Molecular weight:
428.44
Ref: TM-T2S2362
| 1mg | 93.00 € | ||
| 5mg | 258.00 € | ||
| 10mg | 436.00 € | ||
| 25mg | 705.00 € | ||
| 50mg | 920.00 € | ||
| 1mL*10mM (DMSO) | 261.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
VX-702
CAS:745833-23-2
VX-702: selective p38α MAPK inhibitor, potent anti-cytokine for rheumatoid arthritis.
Formula:
C19H12F4N4O2
Purity:
100% - 99%
Color and Shape:
Solid
Molecular weight:
404.32
Ref: TM-T2513
| 10mg | 54.00 € | ||
| 25mg | 83.00 € | ||
| 50mg | 131.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
BGT226 maleate
CAS:1245537-68-1
BGT226 maleate (NVP-BGT226) is a class I PI3K/mTOR inhibitor for PI3Kα/β/γ (IC50: 4/63/38 nM) .
Formula:
C28H25F3N6O2·C4H4O4
Purity:
97.75% - 98.78%
Color and Shape:
Solid
Molecular weight:
650.6
Ref: TM-T6072
| 1mg | 37.00 € | ||
| 5mg | 75.00 € | ||
| 10mg | 111.00 € | ||
| 25mg | 237.00 € | ||
| 50mg | 349.00 € | ||
| 100mg | 498.00 € | ||
| 200mg | 682.00 € | ||
| 1mL*10mM (DMSO) | 97.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
Brivanib (alaninate)
CAS:649735-63-7
Brivanib Alaninate (BMS-582664) is an alaninate salt of a vascular endothelial growth factor receptor 2 …
Formula:
C22H24FN5O4
Purity:
99.23% - 99.66%
Color and Shape:
Solid
Molecular weight:
441.46
Ref: TM-T2576
| 1mg | 62.00 € | ||
| 2mg | 88.00 € | ||
| 5mg | 113.00 € | ||
| 10mg | 196.00 € | ||
| 25mg | 349.00 € | ||
| 50mg | 571.00 € | ||
| 100mg | 909.00 € | ||
| 1mL*10mM (DMSO) | 135.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
Alisol A
CAS:19885-10-0
Alisol A: induces autophagy, anti-cancer, inhibits HepG2, MDA-MB-231, MCF-7 cells.
Formula:
C30H50O5
Purity:
99.77% - 99.94%
Color and Shape:
Solid
Molecular weight:
490.71
Ref: TM-T4519
| 2mg | 37.00 € | ||
| 5mg | 51.00 € | ||
| 10mg | 79.00 € | ||
| 25mg | 113.00 € | ||
| 50mg | 169.00 € | ||
| 100mg | 250.00 € | ||
| 200mg | 359.00 € | ||
| 1mL*10mM (DMSO) | 56.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
SU11274
CAS:658084-23-2
SU11274 (Met Kinase Inhibitor)(IC50=10 nM) is a specific Met inhibitor. It shows no significant effects …
Formula:
C28H30ClN5O4S
Purity:
98.62% - 99.44%
Color and Shape:
Orange Powder
Molecular weight:
568.09
Ref: TM-T6154
| 1mg | 46.00 € | ||
| 2mg | 58.00 € | ||
| 5mg | 95.00 € | ||
| 10mg | 147.00 € | ||
| 25mg | 276.00 € | ||
| 50mg | 455.00 € | ||
| 100mg | 673.00 € | ||
| 1mL*10mM (DMSO) | 150.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
ROC-325
CAS:1859141-26-6
ROC-325: orally active autophagy inhibitor with anticancer effects, induces kidney cancer cell death; selective action.
Formula:
C28H27ClN4OS
Purity:
99.26%
Color and Shape:
Solid
Molecular weight:
503.06
Ref: TM-T16777
| 1mg | 35.00 € | ||
| 2mg | 46.00 € | ||
| 5mg | 63.00 € | ||
| 10mg | 95.00 € | ||
| 25mg | 184.00 € | ||
| 50mg | 305.00 € | ||
| 100mg | 440.00 € | ||
| 500mg | To inquire |
Estimated delivery in United States, on Thursday 2 Jan 2025
Amsacrine
CAS:51264-14-3
Amsacrine (AMSA) (mAMSA) an antineoplastic agent which can intercalate into the DNA of tumor cells.
Formula:
C21H19N3O3S
Purity:
98.59%
Color and Shape:
Yellow Crystalline Powder Solid
Molecular weight:
393.46
Ref: TM-T1206
| 10mg | 51.00 € | ||
| 25mg | 68.00 € | ||
| 50mg | To inquire | ||
| 1mL*10mM (DMSO) | 36.00 € |
Estimated delivery in United States, on Thursday 2 Jan 2025
Cysmethynil
CAS:851636-83-4
Cysmethynil is an indole-based Icmt inhibitor with antitumor activity, induces cell cycle arrest in G1 …
Formula:
C25H32N2O
Purity:
99%
Color and Shape:
Solid
Molecular weight:
376.53
Ref: TM-T36082
| 1mg | 46.00 € | ||
| 2mg | 60.00 € | ||
| 5mg | 87.00 € | ||
| 10mg | 140.00 € | ||
| 25mg | 273.00 € | ||
| 50mg | 437.00 € | ||
| 100mg | 702.00 € | ||
| 500mg | 1,404.00 € |
Estimated delivery in United States, on Thursday 2 Jan 2025
ALLO-1
CAS:37468-32-9
ALLO-1, vital for autophagy, aids in engulfing paternal organelles by binding to worm LC3, LGG-1, …
Formula:
C17H15ClN2O2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
314.77
Ref: TM-T19188
| 5mg | 233.00 € | ||
| 10mg | 422.00 € | ||
| 25mg | 942.00 € |
Estimated delivery in United States, on Thursday 2 Jan 2025
FAAH inhibitor 1
CAS:326866-17-5
FAAH inhibitor 1 (Benzothiazole analog 3) is an effective FAAH inhibitor with an IC50 of …
Formula:
C24H23N3O3S3
Purity:
98.05%
Color and Shape:
Solid
Molecular weight:
497.65
Ref: TM-T11256
| 1mg | 51.00 € | ||
| 5mg | 112.00 € | ||
| 10mg | 175.00 € | ||
| 25mg | 296.00 € | ||
| 50mg | 427.00 € | ||
| 100mg | 598.00 € | ||
| 200mg | 804.00 € | ||
| 1mL*10mM (DMSO) | 124.00 € |
Estimated delivery in United States, on Thursday 2 Jan 2025
GC7 Sulfate
CAS:150417-90-6
GC7 Sulfate blocks DHS, the sole enzyme activating eIF5A2, thus preventing eIF5A2 activation.
Formula:
C8H22N4O4S
Purity:
100% - 99.85%
Color and Shape:
Solid
Molecular weight:
270.35
Ref: TM-T11372
| 5mg | 51.00 € | ||
| 10mg | 96.00 € | ||
| 25mg | 183.00 € | ||
| 50mg | 276.00 € | ||
| 100mg | 447.00 € | ||
| 500mg | 975.00 € |
Estimated delivery in United States, on Thursday 2 Jan 2025
AMDE-1
CAS:478043-30-0
AMDE-1, an autophagy modulator, triggers Atg5-dependent autophagy, recruits Atg16, and induces LC3 lipidation.
Formula:
C18H8ClF6N3
Purity:
90%
Color and Shape:
Solid
Molecular weight:
415.72
Ref: TM-T23716
| 1mg | 90.00 € | ||
| 5mg | 184.00 € | ||
| 10mg | 291.00 € | ||
| 25mg | 526.00 € | ||
| 1mL*10mM (DMSO) | 214.00 € |
Estimated delivery in United States, on Thursday 2 Jan 2025
MDK-6983
CAS:1227476-98-3
MDK-6983 (MDK-6983) is an inhibitor of autophagy and disrupts the dynamics of actin cytoskeleton in …
Formula:
C22H18Cl2N2O3
Purity:
97.55%
Color and Shape:
Solid
Molecular weight:
429.3
Ref: TM-T28001
| 1mg | 113.00 € | ||
| 5mg | 244.00 € | ||
| 10mg | 360.00 € | ||
| 25mg | 550.00 € | ||
| 50mg | 769.00 € | ||
| 100mg | 1,031.00 € | ||
| 500mg | To inquire | ||
| 1mL*10mM (DMSO) | 282.00 € |
Estimated delivery in United States, on Thursday 2 Jan 2025
LRRK2-IN-7
CAS:2307277-93-4
LRRK2-IN-7: potent, selective CNS-active LRRK2 inhibitor, IC50 0.9 nM, >1000x selectivity vs kinases/channels/CYPs.
Formula:
C24H26N6O
Purity:
99.26%
Color and Shape:
Solid
Molecular weight:
414.5
Ref: TM-T73176
| 1mg | 226.00 € | ||
| 5mg | 563.00 € | ||
| 10mg | 900.00 € | ||
| 25mg | 1,435.00 € | ||
| 50mg | 1,869.00 € |
Estimated delivery in United States, on Thursday 2 Jan 2025
