PI3K/Akt/mTOR Signaling
PI3K/Akt/mTOR signaling inhibitors are compounds that target the phosphoinositide 3-kinase (PI3K), Akt kinase, and mammalian target of rapamycin (mTOR) pathways. These pathways are critical regulators of cell growth, survival, metabolism, and autophagy, making them key targets in cancer research and metabolic disorders. Inhibiting these pathways can help to control tumor growth and proliferation, offering potential therapeutic strategies for various cancers and other diseases characterized by dysregulated cell signaling. At CymitQuimica, we offer a comprehensive selection of high-quality PI3K/Akt/mTOR inhibitors to support your research in oncology, cellular signaling, and metabolic diseases.
Read more
Subcategories of "PI3K/Akt/mTOR Signaling"
Show 2 more subcategories
Products of "PI3K/Akt/mTOR Signaling"
CC-115
CAS:1228013-15-7
CC-115 is a inhibitor of mTOR/DNA-PK (IC50= 21/ 13 nM).
Formula:
C16H16N8O
Purity:
86.79% - 99.22%
Color and Shape:
Solid
Molecular weight:
336.35
Ref: TM-T3541
| 2mg | 45.00 € | ||
| 5mg | 65.00 € | ||
| 10mg | 94.00 € | ||
| 25mg | 175.00 € | ||
| 50mg | 294.00 € | ||
| 100mg | 461.00 € | ||
| 1mL*10mM (DMSO) | 73.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
PQR530
CAS:1927857-61-1
PQR530, a potent dual PI3K/mTORC1/2 inhibitor, blocks PKB and pS6 phosphorylation (IC50: 0.07 μM) and …
Formula:
C18H23F2N7O2
Purity:
99.50%
Color and Shape:
Solid
Molecular weight:
407.42
Ref: TM-T16567
| 1mg | 34.00 € | ||
| 5mg | 72.00 € | ||
| 10mg | 93.00 € | ||
| 25mg | 181.00 € | ||
| 50mg | 269.00 € | ||
| 100mg | 392.00 € | ||
| 1mL*10mM (DMSO) | 80.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
EX229
CAS:1219739-36-2
EX229 (C991) is an allosteric activator of AMPK, with Kds of 0.06 μM, 0.06 μM …
Formula:
C24H18ClN3O3
Purity:
99.22% - 99.36%
Color and Shape:
Solid
Molecular weight:
431.87
Ref: TM-TQ0028
| 1mg | 37.00 € | ||
| 2mg | 52.00 € | ||
| 5mg | 73.00 € | ||
| 10mg | 109.00 € | ||
| 25mg | 217.00 € | ||
| 50mg | 368.00 € | ||
| 100mg | 553.00 € | ||
| 1mL*10mM (DMSO) | 84.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Olmutinib
CAS:1353550-13-6
Olmutinib is an oral mutant-specific EGFR inhibitor for cancer treatment with potential lower toxicity.
Formula:
C26H26N6O2S
Purity:
99.27%
Color and Shape:
Solid
Molecular weight:
486.59
Ref: TM-T6918
| 2mg | 39.00 € | ||
| 5mg | 56.00 € | ||
| 10mg | 87.00 € | ||
| 25mg | 134.00 € | ||
| 50mg | 176.00 € | ||
| 100mg | 276.00 € | ||
| 200mg | 454.00 € | ||
| 1mL*10mM (DMSO) | 59.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
A-769662
CAS:844499-71-4
A-769662 is an effective, reversible AMPK activator(EC50=0.8 μM).
Formula:
C20H12N2O3S
Purity:
98.23% - 99.58%
Color and Shape:
Solid
Molecular weight:
360.39
Ref: TM-T2468
| 2mg | 39.00 € | ||
| 5mg | 56.00 € | ||
| 10mg | 78.00 € | ||
| 25mg | 140.00 € | ||
| 50mg | 251.00 € | ||
| 100mg | 464.00 € | ||
| 500mg | 994.00 € | ||
| 1mL*10mM (DMSO) | 59.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
EBE-A22
CAS:229476-53-3
EBE-A22 (PD153035 Analog 63) is a derivative of PD 153035 which can inhibit ErbB-1-phosphorylation, whereas …
Formula:
C17H16BrN3O2
Purity:
99.85% - 99.88%
Color and Shape:
Solid
Molecular weight:
374.23
Ref: TM-T3558
| 2mg | 37.00 € | ||
| 5mg | 51.00 € | ||
| 10mg | 73.00 € | ||
| 25mg | 136.00 € | ||
| 50mg | 200.00 € | ||
| 100mg | 301.00 € | ||
| 200mg | 424.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Tesevatinib
CAS:781613-23-8
Tesevatinib (XL-647) is an oral, multi-targeted tyrosine kinase inhibitor.Cost-effective and quality-assured.
Formula:
C24H25Cl2FN4O2
Purity:
97.89% - 97.89%
Color and Shape:
Solid
Molecular weight:
491.39
Ref: TM-TQ0166
| 1mg | 107.00 € | ||
| 2mg | 152.00 € | ||
| 5mg | 237.00 € | ||
| 10mg | 458.00 € | ||
| 25mg | 749.00 € | ||
| 50mg | 1,025.00 € | ||
| 1mL*10mM (DMSO) | 256.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
YU238259
CAS:1943733-16-1
YU238259 is a novel inhibitor of homology-dependent DNA repair(HDR), but does not inhibit non-homologous end-joining …
Formula:
C22H22ClN3O4S
Purity:
99.12% - 99.43%
Color and Shape:
Solid
Molecular weight:
459.95
Ref: TM-T4339
| 1mg | 47.00 € | ||
| 2mg | 62.00 € | ||
| 5mg | 87.00 € | ||
| 10mg | 151.00 € | ||
| 25mg | 302.00 € | ||
| 50mg | 537.00 € | ||
| 100mg | 771.00 € | ||
| 500mg | 1,576.00 € | ||
| 1mL*10mM (DMSO) | 87.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Cyasterone
CAS:17086-76-9
Cyasterone (Cyasteron), a natural EGFR inhibitor, can inhibit the growth of A549 and MGC823 cells, …
Formula:
C29H44O8
Purity:
99.26% - 99.32%
Color and Shape:
Solid
Molecular weight:
520.65
Ref: TM-T3870
| 1mg | 35.00 € | ||
| 5mg | 71.00 € | ||
| 10mg | 113.00 € | ||
| 25mg | 205.00 € | ||
| 50mg | 306.00 € | ||
| 100mg | 456.00 € | ||
| 200mg | 386.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
KU-0060648
CAS:881375-00-4
KU-0060648 is a dual inhibitor of DNA-PK and PI3Kα, PI3Kβ, PI3Kδ with IC50 of 8.6 …
Formula:
C33H34N4O4S
Purity:
98.75%
Color and Shape:
Solid
Molecular weight:
582.71
Ref: TM-T6557
| 1mg | 58.00 € | ||
| 2mg | 81.00 € | ||
| 5mg | 104.00 € | ||
| 10mg | 168.00 € | ||
| 25mg | 295.00 € | ||
| 50mg | 441.00 € | ||
| 100mg | 631.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Genistein
CAS:446-72-0
Genistein (NPI 031L) is a natural soy isoflavone, a multi-targeted tyrosine kinase inhibitor. Genistein has …
Formula:
C15H10O5
Purity:
98.22% - 99.69%
Color and Shape:
Rectangular Or Six-Sided Rods From 60% Alcohol Dendritic Needles From Ether Solid
Molecular weight:
270.24
Ref: TM-T1737
| 50mg | 45.00 € | ||
| 100mg | 58.00 € | ||
| 500mg | 93.00 € | ||
| 1mL*10mM (DMSO) | 63.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Rostafuroxin
CAS:156722-18-8
Rostafuroxin (PST 2238) has been used in trials studying the treatment of Essential Hypertension.
Formula:
C23H34O4
Purity:
100% - 99.08%
Color and Shape:
Solid
Molecular weight:
374.51
Ref: TM-T2621
| 2mg | 43.00 € | ||
| 5mg | 64.00 € | ||
| 10mg | 105.00 € | ||
| 25mg | 184.00 € | ||
| 50mg | 345.00 € | ||
| 100mg | 510.00 € | ||
| 1mL*10mM (DMSO) | 72.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
WZ-3146
CAS:1214265-56-1
WZ3146: EGFR(L858R/E746_A750) inhibitor, IC50=2 nM, selective, doesn't block ERBB2(T798I).
Formula:
C24H25ClN6O2
Purity:
97.15%
Color and Shape:
Solid
Molecular weight:
464.95
Ref: TM-T6733
| 1mg | 52.00 € | ||
| 2mg | 73.00 € | ||
| 5mg | 95.00 € | ||
| 10mg | 176.00 € | ||
| 25mg | 312.00 € | ||
| 50mg | 499.00 € | ||
| 100mg | 713.00 € | ||
| 1mL*10mM (DMSO) | 106.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Almonertinib mesylate
CAS:2134096-06-1
Almonertinib mesylate: EGFR tyrosine kinase inhibitor, targets EGFR-mutant non-small cell lung cancer.
Formula:
C31H39N7O5S
Purity:
98.85%
Color and Shape:
Solid
Molecular weight:
621.75
Ref: TM-T9865
| 1mg | 53.00 € | ||
| 5mg | 112.00 € | ||
| 10mg | 181.00 € | ||
| 25mg | 307.00 € | ||
| 50mg | 434.00 € | ||
| 100mg | 616.00 € | ||
| 200mg | 811.00 € | ||
| 1mL*10mM (DMSO) | 164.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Desmethyl-VS-5584
CAS:1246535-95-4
Desmethyl-VS-5584 is a dimethyl analog of VS-5584, which is a novel and highly selective PI3K/mTOR …
Formula:
C16H20N8O
Purity:
100%
Color and Shape:
Solid
Molecular weight:
340.38
Ref: TM-T4199
| 1mg | 58.00 € | ||
| 2mg | 93.00 € | ||
| 5mg | 148.00 € | ||
| 10mg | 251.00 € | ||
| 25mg | 421.00 € | ||
| 50mg | 620.00 € | ||
| 100mg | 884.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
CZC-8004
CAS:916603-07-1
CZC-8004 (CZC-00008004) is a pan-kinase(ABL kinase) inhibitor and binds a range of tyrosine kinases.
Formula:
C17H16FN5
Purity:
99.29%
Color and Shape:
Solid
Molecular weight:
309.34
Ref: TM-T7186
| 1mg | 47.00 € | ||
| 5mg | 87.00 € | ||
| 10mg | 143.00 € | ||
| 25mg | 294.00 € | ||
| 50mg | 439.00 € | ||
| 100mg | 632.00 € | ||
| 1mL*10mM (DMSO) | 96.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
LY-294002 hydrochloride
CAS:934389-88-5
LY-294002 HCl (NSC 697286) is a stable PI3K inhibitor (IC50: 0.5-0.97 µM) and prevents autophagosome …
Formula:
C19H17NO3·HCl
Purity:
99.95%
Color and Shape:
Solid
Molecular weight:
343.81
Ref: TM-T4079
| 1mg | 43.00 € | ||
| 2mg | 54.00 € | ||
| 5mg | 73.00 € | ||
| 10mg | 95.00 € | ||
| 25mg | 172.00 € | ||
| 50mg | 278.00 € | ||
| 100mg | 440.00 € | ||
| 1mL*10mM (DMSO) | 75.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
MHY-1685
CAS:27406-31-1
MHY-1685 is a mammalian target of rapamycin (mTOR) inhibitor and a senescence inhibitor that can …
Formula:
C11H8N2O4
Purity:
98.44%
Color and Shape:
Solid
Molecular weight:
232.19
Ref: TM-T40351
| 25mg | 34.00 € | ||
| 1mL*10mM (DMSO) | 36.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
GSK 3 Inhibitor IX
CAS:667463-62-9
GSK 3 Inhibitor IX (6-BIO) is a selective reversible, ATP-competitive inhibitor of GSK-3α/β and CDK1-cyclinB …
Formula:
C16H10BrN3O2
Purity:
98% - 99.72%
Color and Shape:
Solid
Molecular weight:
356.17
Ref: TM-T1917
| 1mg | 44.00 € | ||
| 2mg | 54.00 € | ||
| 5mg | 81.00 € | ||
| 10mg | 100.00 € | ||
| 25mg | 223.00 € | ||
| 50mg | 402.00 € | ||
| 100mg | 599.00 € | ||
| 500mg | 1,277.00 € | ||
| 1mL*10mM (DMSO) | 91.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
(Rac)-JBJ-04-125-02
CAS:2140807-05-0
(Rac)-JBJ-04-125-02 (JBJ-04-125-02) is effective as a single agent in both in vitro and in vivo …
Formula:
C29H26FN5O3S
Purity:
95.85%
Color and Shape:
Solid
Molecular weight:
543.61
Ref: TM-T8872
| 1mg | 103.00 € | ||
| 5mg | 212.00 € | ||
| 10mg | 346.00 € | ||
| 25mg | 585.00 € | ||
| 50mg | 832.00 € | ||
| 100mg | 1,133.00 € | ||
| 1mL*10mM (DMSO) | 260.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
