PI3K/Akt/mTOR Signaling
PI3K/Akt/mTOR signaling inhibitors are compounds that target the phosphoinositide 3-kinase (PI3K), Akt kinase, and mammalian target of rapamycin (mTOR) pathways. These pathways are critical regulators of cell growth, survival, metabolism, and autophagy, making them key targets in cancer research and metabolic disorders. Inhibiting these pathways can help to control tumor growth and proliferation, offering potential therapeutic strategies for various cancers and other diseases characterized by dysregulated cell signaling. At CymitQuimica, we offer a comprehensive selection of high-quality PI3K/Akt/mTOR inhibitors to support your research in oncology, cellular signaling, and metabolic diseases.
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Subcategories of "PI3K/Akt/mTOR Signaling"
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Products of "PI3K/Akt/mTOR Signaling"
TWS119
CAS:601514-19-6
TWS119 is a GSK-3β inhibitor; capable of inducing neuronal differentiation
Formula:
C18H14N4O2
Purity:
98.02% - 99.13%
Color and Shape:
Solid
Molecular weight:
318.33
Ref: TM-T2166
| 5mg | 50.00 € | ||
| 10mg | 75.00 € | ||
| 25mg | 132.00 € | ||
| 50mg | 235.00 € | ||
| 100mg | 406.00 € | ||
| 1mL*10mM (DMSO) | 52.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Leptomycin B
CAS:87081-35-4
Leptomycin B: potent CRM1 inhibitor, blocks protein nuclear export and cell cycle, antifungal, modifies cysteine.
Formula:
C33H48O6
Purity:
99.04% - 99.71%
Color and Shape:
White Crystalline Solid
Molecular weight:
540.73
Ref: TM-T15735
| 1mg | 203.00 € | ||
| 2mg | 335.00 € | ||
| 5mg | 611.00 € | ||
| 10mg | 867.00 € | ||
| 25mg | 1,296.00 € | ||
| 50mg | 1,747.00 € | ||
| 100mg | 2,349.00 € | ||
| 1mL*10mM (DMSO) | 280.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
GSK3i XIII
CAS:404828-08-6
GSK3i XIII (GSK3 inhibitor XIII) is a GSK-3 ATP-binding site inhibitor.
Formula:
C18H19N5
Purity:
98.12%
Color and Shape:
Solid
Molecular weight:
305.38
Ref: TM-T24111
| 1mg | 98.00 € | ||
| 5mg | 193.00 € | ||
| 10mg | 289.00 € | ||
| 25mg | 487.00 € | ||
| 50mg | 707.00 € | ||
| 100mg | 994.00 € | ||
| 500mg | 1,977.00 € | ||
| 1mL*10mM (DMSO) | 214.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Pilaralisib
CAS:934526-89-3
Pilaralisib (XL-147) is an orally available small molecule that selectively inhibits the activity of phosphoinositide-3 …
Formula:
C25H25ClN6O4S
Purity:
98.24% - 99.61%
Color and Shape:
Solid
Molecular weight:
541.02
Ref: TM-T2365
| 2mg | 49.00 € | ||
| 5mg | 68.00 € | ||
| 10mg | 114.00 € | ||
| 25mg | 183.00 € | ||
| 50mg | 277.00 € | ||
| 100mg | 388.00 € | ||
| 1mL*10mM (DMSO) | 89.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
SF2523
CAS:1174428-47-7
SF2523 is a highly selective and potent inhibitor.
Formula:
C19H17NO5S
Purity:
97.78% - 98.06%
Color and Shape:
Solid
Molecular weight:
371.41
Ref: TM-T3986
| 1mg | 37.00 € | ||
| 5mg | 79.00 € | ||
| 10mg | 120.00 € | ||
| 25mg | 275.00 € | ||
| 50mg | 433.00 € | ||
| 100mg | 639.00 € | ||
| 200mg | 530.00 € | ||
| 500mg | 1,336.00 € | ||
| 1mL*10mM (DMSO) | 87.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
DS-7423
CAS:1222104-37-1
DS-7423: a dual PI3K/mTOR inhibitor; IC50s-PI3Kα: 15.6 nM, mTOR: 34.9 nM, PI3Kβ: 1,143 nM, PI3Kγ: …
Formula:
C22H27F3N10O2
Purity:
99.68%
Color and Shape:
Solid
Molecular weight:
520.51
Ref: TM-T36083
| 1mg | 127.00 € | ||
| 5mg | 283.00 € | ||
| 10mg | 433.00 € | ||
| 25mg | 708.00 € | ||
| 50mg | 938.00 € | ||
| 100mg | 1,378.00 € | ||
| 200mg | 1,081.00 € | ||
| 1mL*10mM (DMSO) | 322.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
OTSSP167 hydrochloride
CAS:1431698-10-0
OTSSP167 hydrochloride is a highly potent inhibitor of MELK(IC50 : 0.41 nM).
Formula:
C25H29Cl3N4O2
Purity:
99.97%
Color and Shape:
Solid
Molecular weight:
523.88
Ref: TM-T21559
| 1mg | 40.00 € | ||
| 2mg | 52.00 € | ||
| 5mg | 87.00 € | ||
| 10mg | 119.00 € | ||
| 25mg | 186.00 € | ||
| 50mg | 349.00 € | ||
| 100mg | 522.00 € | ||
| 1mL*10mM (DMSO) | 91.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Gedatolisib
CAS:1197160-78-3
Gedatolisib (PF-05212384) is a highly effective dual inhibitor targeting the PI3Kα/γ (IC50: 0.4/5.4 nM)and mTOR …
Formula:
C32H41N9O4
Purity:
98% - 99.48%
Color and Shape:
Solid
Molecular weight:
615.73
Ref: TM-T1970
| 2mg | 49.00 € | ||
| 5mg | 78.00 € | ||
| 10mg | 118.00 € | ||
| 25mg | 223.00 € | ||
| 50mg | 417.00 € | ||
| 100mg | 616.00 € | ||
| 500mg | 1,296.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Pelitinib
CAS:257933-82-7
Pelitinib (EKB-569) (EKB-569) is an effective irreversible EGFR inhibitor (IC50: 38.5 nM).
Formula:
C24H23ClFN5O2
Purity:
98.37% - 99.86%
Color and Shape:
Off-White Solid
Molecular weight:
467.92
Ref: TM-T2327
| 5mg | 55.00 € | ||
| 10mg | 71.00 € | ||
| 25mg | 109.00 € | ||
| 50mg | 133.00 € | ||
| 100mg | 189.00 € | ||
| 500mg | 455.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
CNX-2006
CAS:1375465-09-0
CNX-2006 is a novel irreversible mutant-selective EGFR inhibitor with IC50 of < 20 nM, with very …
Formula:
C26H27F4N7O2
Purity:
98.85% - 99.16%
Color and Shape:
Solid
Molecular weight:
545.53
Ref: TM-T6008
| 1mg | 40.00 € | ||
| 2mg | 52.00 € | ||
| 5mg | 82.00 € | ||
| 10mg | 123.00 € | ||
| 25mg | 219.00 € | ||
| 50mg | 397.00 € | ||
| 1mL*10mM (DMSO) | 90.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
8-Chloroadenosine
CAS:34408-14-5
8-Chloroadenosine (NSC-354258) is a 5' AMP-activated protein kinase agonist potentially for the treatment of chronic …
Formula:
C10H12ClN5O4
Purity:
98.75% - 99.48%
Color and Shape:
Solid
Molecular weight:
301.69
Ref: TM-T19661
| 1mg | 36.00 € | ||
| 5mg | 120.00 € | ||
| 10mg | 186.00 € | ||
| 25mg | 327.00 € | ||
| 50mg | 487.00 € | ||
| 100mg | 692.00 € | ||
| 500mg | 1,388.00 € | ||
| 1mL*10mM (DMSO) | 164.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Sapitinib
CAS:848942-61-0
Sapitinib (AZD-8931) , a reversible, ATP competitive inhibitor of EGFR(IC50=4 nM), ErbB2(IC50=3 nM) and ErbB3(IC50=4 …
Formula:
C23H25ClFN5O3
Purity:
98.35% - 99.83%
Color and Shape:
Solid
Molecular weight:
473.93
Ref: TM-T6092
| 2mg | 38.00 € | ||
| 5mg | 56.00 € | ||
| 10mg | 85.00 € | ||
| 25mg | 109.00 € | ||
| 50mg | 163.00 € | ||
| 100mg | 235.00 € | ||
| 1mL*10mM (DMSO) | 59.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Mobocertinib
CAS:1847461-43-1
Mobocertinib (tak788) is a potent inhibitor of epidermal growth factor receptor (EGFR) and an antineoplastic …
Formula:
C32H39N7O4
Purity:
98.66% - 99.47%
Color and Shape:
Solid
Molecular weight:
585.7
Ref: TM-T8151
| 5mg | 35.00 € | ||
| 10mg | 51.00 € | ||
| 25mg | 78.00 € | ||
| 50mg | 118.00 € | ||
| 100mg | 185.00 € | ||
| 500mg | 479.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
CUDC-101
CAS:1012054-59-9
CUDC-101 is a potent inhibitor of HDAC, EGFR and HER2 with IC50s of 4.4, 2.4 …
Formula:
C24H26N4O4
Purity:
95.76% - 99.12%
Color and Shape:
Solid
Molecular weight:
434.49
Ref: TM-T3108
| 5mg | 51.00 € | ||
| 10mg | 83.00 € | ||
| 25mg | 121.00 € | ||
| 50mg | 194.00 € | ||
| 100mg | 344.00 € | ||
| 200mg | 511.00 € | ||
| 500mg | 827.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Afatinib
CAS:850140-72-6
Afatinib (BIBW 2992) is an irreversible and orally EGFR family inhibitor that inhibits EGFR and …
Formula:
C24H25ClFN5O3
Purity:
97.56% - 99.9%
Color and Shape:
Off-White Solid
Molecular weight:
485.94
Ref: TM-T21312
| 5mg | 35.00 € | ||
| 10mg | 51.00 € | ||
| 25mg | 84.00 € | ||
| 50mg | 113.00 € | ||
| 100mg | 142.00 € | ||
| 200mg | 174.00 € | ||
| 500mg | 294.00 € | ||
| 1mL*10mM (DMSO) | 53.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Duvelisib
CAS:1201438-56-3
Duvelisib (INK1197, IPI-145) is a selective inhibitor of phosphatidylinositol 3-kinase (PI3K) and p100δ.Cost-effective and quality-assured.
Formula:
C22H17ClN6O
Purity:
99.38% - 99.45%
Color and Shape:
Solid
Molecular weight:
416.86
Ref: TM-T1988
| 2mg | 47.00 € | ||
| 5mg | 66.00 € | ||
| 10mg | 92.00 € | ||
| 50mg | 152.00 € | ||
| 100mg | 238.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
PIK-75
CAS:372196-67-3
PIK-75, a DNA-PK and PI3K inhibitor, suppresses DNA-PK(IC50=2 nM), p110α(IC50=5.8 nM) and p110γ(IC50=76 nM).
Formula:
C16H14BrN5O4S
Purity:
100% - 99.88%
Color and Shape:
Solid
Molecular weight:
452.28
Ref: TM-T2667
| 5mg | 45.00 € | ||
| 10mg | 56.00 € | ||
| 25mg | 109.00 € | ||
| 50mg | 180.00 € | ||
| 100mg | 276.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
PD153035
CAS:153436-54-5
PD153035 (NSC-669364) hydrochloride is an effective and selective inhibitor of EGFR (Ki/IC50: 5.2/29 pM, in …
Formula:
C16H14BrN3O2
Purity:
98.92% - 99.31%
Color and Shape:
Solid
Molecular weight:
360.21
Ref: TM-T2041
| 10mg | 41.00 € | ||
| 25mg | 78.00 € | ||
| 50mg | 128.00 € | ||
| 100mg | 216.00 € | ||
| 200mg | 323.00 € | ||
| 1mL*10mM (DMSO) | 39.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Acalisib
CAS:870281-34-8
Acalisib (CAL-120) (GS-9820) is a potent and selective inhibitor of PI3Kδ.
Formula:
C21H16FN7O
Purity:
98.99% - ≥95%
Color and Shape:
Solid
Molecular weight:
401.4
Ref: TM-T2682
| 5mg | 50.00 € | ||
| 10mg | 83.00 € | ||
| 25mg | 133.00 € | ||
| 50mg | 195.00 € | ||
| 100mg | 272.00 € | ||
| 200mg | 409.00 € | ||
| 1mL*10mM (DMSO) | 51.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Nazartinib
CAS:1508250-71-2
Nazartinib (EGF816) (EGF816, NVS-816) is a covalent, irreversible, mutant-selective EGFR inhibitor that has nanomolar inhibitory …
Formula:
C26H31ClN6O2
Purity:
98% - ≥95%
Color and Shape:
Solid Powder
Molecular weight:
495.02
Ref: TM-T3506
| 1mg | 37.00 € | ||
| 5mg | 78.00 € | ||
| 10mg | 119.00 € | ||
| 25mg | 185.00 € | ||
| 50mg | 349.00 € | ||
| 100mg | 522.00 € | ||
| 500mg | 1,133.00 € | ||
| 1mL*10mM (DMSO) | 86.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
