PI3K/Akt/mTOR Signaling
PI3K/Akt/mTOR signaling inhibitors are compounds that target the phosphoinositide 3-kinase (PI3K), Akt kinase, and mammalian target of rapamycin (mTOR) pathways. These pathways are critical regulators of cell growth, survival, metabolism, and autophagy, making them key targets in cancer research and metabolic disorders. Inhibiting these pathways can help to control tumor growth and proliferation, offering potential therapeutic strategies for various cancers and other diseases characterized by dysregulated cell signaling. At CymitQuimica, we offer a comprehensive selection of high-quality PI3K/Akt/mTOR inhibitors to support your research in oncology, cellular signaling, and metabolic diseases.
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Subcategories of "PI3K/Akt/mTOR Signaling"
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Products of "PI3K/Akt/mTOR Signaling"
GSK3-IN-2
CAS:380450-97-5
GSK3-IN-2 is a potent GSK3 inhibitor for the treatment of diabetes and neurodegenerative diseases.
Formula:
C17H19N3OS
Purity:
98.8%
Color and Shape:
Liquid
Molecular weight:
313.42
Ref: TM-T73270
| 1mg | 78.00 € | ||
| 5mg | 170.00 € | ||
| 10mg | 272.00 € | ||
| 25mg | 551.00 € | ||
| 50mg | 784.00 € | ||
| 100mg | 1,077.00 € | ||
| 500mg | 2,164.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
Cloperastine fendizoate
CAS:85187-37-7
Cloperastine fendizoate (Hustazol) inhibits the hERG K+ currents in a concentration-dependent manner (IC50: 27 nM).
Formula:
C40H38ClNO5
Purity:
99.85%
Color and Shape:
Solid
Molecular weight:
648.19
Ref: TM-T13619
| 500mg | 49.00 € | ||
| 1mL*10mM (DMSO) | 51.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
ABC1183
CAS:1042735-18-1
ABC1183, an oral diaminothiazole, inhibits GSK3α/β, CDK9, hinders cancer cell growth, induces G2/M arrest, and …
Formula:
C18H14N4OS
Purity:
98.53%
Color and Shape:
Solid
Molecular weight:
334.39
Ref: TM-T23601
| 5mg | 41.00 € | ||
| 10mg | 63.00 € | ||
| 25mg | To inquire | ||
| 50mg | To inquire | ||
| 1mL*10mM (DMSO) | 47.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
EGFR-IN-88
CAS:2944452-34-8
EGFR-IN-88 (Compound 4i), an EGFR inhibitor with an IC50 of 87 nM, exhibits cytotoxic effects …
Formula:
C22H18Cl2N4O2S
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
473.37
Ref: TM-T79694
| 25mg | 1,410.00 € | ||
| 50mg | 1,851.00 € | ||
| 100mg | 2,337.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
P-2281
CAS:1112994-35-0
P-2281 is an mTOR inhibitor with anticancer and anti-inflammatory properties.P-2281 inhibits dextran sulfate sodium (DSS)-induced …
Formula:
C9H8ClN3O
Purity:
99.95%
Color and Shape:
Solid
Molecular weight:
209.63
Ref: TM-T28285
| 1mg | 152.00 € | ||
| 5mg | 368.00 € | ||
| 10mg | 528.00 € | ||
| 25mg | 907.00 € | ||
| 50mg | 1,197.00 € | ||
| 100mg | 1,642.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
Sunvozertinib
CAS:2370013-12-8
Sunvozertinib (DZD9008) is a potent ErbBs and BTK inhibitor, with inhibitory effects on EGFR, Her2.Cost-effective …
Formula:
C29H35ClFN7O3
Purity:
98.11% - 99.71%
Color and Shape:
Liquid
Molecular weight:
584.08
Ref: TM-T64124
| 1mg | 36.00 € | ||
| 5mg | 63.00 € | ||
| 10mg | 90.00 € | ||
| 25mg | 130.00 € | ||
| 50mg | 210.00 € | ||
| 100mg | 370.00 € | ||
| 500mg | 1,375.00 € | ||
| 1mL*10mM (DMSO) | 158.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
GSK-3β inhibitor 11
CAS:536731-65-4
GSK-3β inhibitor 11 (compound 21) is a potent inhibitor of glycogen synthase kinase-3β (GSK-3β) with …
Formula:
C20H15N3O4S
Purity:
97.33%
Color and Shape:
Solid
Molecular weight:
393.42
Ref: TM-T61809
| 5mg | 74.00 € | ||
| 10mg | 105.00 € | ||
| 25mg | 212.00 € | ||
| 50mg | 343.00 € | ||
| 100mg | 549.00 € | ||
| 500mg | 1,171.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
PI3Kδ-IN-3
CAS:1431540-99-6
PI3Kδ-IN-3 (TC KHNS 11) is a PI3Kδ inhibitor with an IC50 value of 9 nM.PI3Kδ-IN-3 …
Formula:
C28H24N6O3
Purity:
98.43%
Color and Shape:
Solid
Molecular weight:
492.53
Ref: TM-T26252
| 1mg | 93.00 € | ||
| 5mg | 182.00 € | ||
| 10mg | 291.00 € | ||
| 25mg | 494.00 € | ||
| 50mg | 715.00 € | ||
| 100mg | 1,000.00 € | ||
| 500mg | 1,995.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
LY 456236 hydrochloride
CAS:338736-46-2
LY 456236 hydrochloride (MPMQ hydrochloride) is an mGlu1 receptor antagonist with an ic50 value of …
Formula:
C16H16ClN3O2
Purity:
99.89%
Color and Shape:
Solid
Molecular weight:
317.77
Ref: TM-T22954
| 1mg | 41.00 € | ||
| 5mg | 87.00 € | ||
| 10mg | 124.00 € | ||
| 25mg | 258.00 € | ||
| 50mg | 423.00 € | ||
| 100mg | 608.00 € | ||
| 500mg | 1,262.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
AMPK activator 12
CAS:431920-24-0
AMPK activator 12 is an AMPK activator and GDF15 inducer that elevates the expression level …
Formula:
C23H24BrNO2
Purity:
99.27%
Color and Shape:
Liquid
Molecular weight:
426.35
Ref: TM-T78791
| 1mg | 56.00 € | ||
| 5mg | 118.00 € | ||
| 10mg | 182.00 € | ||
| 25mg | 367.00 € | ||
| 50mg | 546.00 € | ||
| 100mg | 777.00 € | ||
| 1mL*10mM (DMSO) | 46.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
Dehydroglyasperin D
CAS:517885-72-2
Dehydroglyasperin D exhibits anticancer, anti-inflammatory, anti-obesity, antioxidant and anti-aldose reductase effects, it inhibits the proliferation …
Formula:
C22H24O5
Purity:
98%
Color and Shape:
Solid
Molecular weight:
368.42
Ref: TM-TMA0291
| 25mg | 1,549.00 € | ||
| 50mg | 2,031.00 € | ||
| 100mg | 2,609.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
YKL-06-062
CAS:2172617-16-0
YKL-06-062 is a second-generation salt-inducible kinase (SIK) inhibitor that inhibits SIK1, SIK2 and SIK3 with …
Formula:
C31H39N7O
Purity:
99.95%
Color and Shape:
Solid
Molecular weight:
525.69
Ref: TM-T17272
| 1mg | 90.00 € | ||
| 5mg | 213.00 € | ||
| 10mg | 348.00 € | ||
| 25mg | 587.00 € | ||
| 50mg | 832.00 € | ||
| 100mg | 1,132.00 € | ||
| 500mg | 2,276.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
A-935142
CAS:1031335-85-9
A-935142 enhances hERG (Kv 11.1) channels, slows inactivation, promotes activation, and shortens repolarization.
Formula:
C18H19F3N2O2
Purity:
100% - 100%
Color and Shape:
Solid
Molecular weight:
352.35
Ref: TM-T14077
| 1mg | 326.00 € | ||
| 5mg | 769.00 € | ||
| 10mg | 1,050.00 € | ||
| 25mg | 1,486.00 € | ||
| 50mg | 1,850.00 € | ||
| 100mg | 2,322.00 € | ||
| 500mg | 4,547.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
EGFR-IN-89
CAS:2413029-40-8
EGFR-IN-89 (compound 13k) is a fourth-generation inhibitor selectively targeting EGFR mutations, exhibiting potent activity with …
Formula:
C26H31FN8O2S
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
538.64
Ref: TM-T79775
| 25mg | 1,410.00 € | ||
| 50mg | 1,851.00 € | ||
| 100mg | 2,337.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
FD2056
CAS:2685870-87-3
FD2056 is a potent, orally active PI3K inhibitor, with IC50 values of 0.30, 0.80, 1.10, …
Formula:
C23H17ClN6O2S
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
476.94
Ref: TM-T79370
| 25mg | 1,410.00 € | ||
| 50mg | 1,851.00 € | ||
| 100mg | 2,337.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
EGFR-IN-5
CAS:2225887-26-1
EGFR-IN-5 inhibits EGFR & mutants; IC50: EGFR 10.4nM, L858R 1.1nM, L858R/T790M 34nM, L858R/T790M/C797S 7.2nM.
Formula:
C31H38FN9O
Purity:
98.17%
Color and Shape:
Solid
Molecular weight:
571.69
Ref: TM-T11160
| 1mg | 106.00 € | ||
| 5mg | 249.00 € | ||
| 10mg | 442.00 € | ||
| 25mg | 887.00 € | ||
| 50mg | 1,346.00 € | ||
| 100mg | 2,349.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
AZ044
CAS:1800017-49-5
AZ044 is a potent, selective inhibitor of type III phosphatidylinositol-4-kinase alpha-subtype (PI4KIIIalpha).
Formula:
C24H27N3O3S
Purity:
98.22%
Color and Shape:
Solid
Molecular weight:
437.55
Ref: TM-T26698
| 1mg | 57.00 € | ||
| 5mg | 120.00 € | ||
| 10mg | 186.00 € | ||
| 25mg | 427.00 € | ||
| 50mg | 738.00 € | ||
| 100mg | 1,201.00 € | ||
| 200mg | 1,622.00 € | ||
| 1mL*10mM (DMSO) | 144.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
DBPR112
CAS:1226549-49-0
DBPR112: oral furanopyrimidine EGFR inhibitor; IC50: 15 nM (EGFRWT), 48 nM (L858R/T790M); blocks ATP site, …
Formula:
C32H31N5O3
Purity:
98.29%
Color and Shape:
Solid
Molecular weight:
533.62
Ref: TM-T10965
| 1mg | 75.00 € | ||
| 5mg | 167.00 € | ||
| 10mg | 300.00 € | ||
| 25mg | 484.00 € | ||
| 50mg | 645.00 € | ||
| 100mg | 888.00 € | ||
| 1mL*10mM (DMSO) | 187.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
GSK-3β inhibitor 2
CAS:1702428-31-6
GSK-3β inhibitor 2 (5-Thiazolecarboxamide,2-[2-[(cyclopropylcarbonyl)amino]-4-pyridinyl]-4-methoxy-) is a BBB-crossing and selective inhibitor of GSK-3β (IC50
Formula:
C14H14N4O3S
Purity:
95.69%
Color and Shape:
Solid
Molecular weight:
318.35
Ref: TM-T11471
| 5mg | 54.00 € | ||
| 10mg | 73.00 € | ||
| 25mg | 103.00 € | ||
| 50mg | 183.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
3F8
CAS:159109-11-2
3F8 is a selective GSK-3β inhibitor that can be used as a new tool and …
Formula:
C15H14N2O4
Purity:
98.05% - 98.49%
Color and Shape:
Solid
Molecular weight:
286.28
Ref: TM-T22180
| 1mg | 111.00 € | ||
| 5mg | 266.00 € | ||
| 10mg | 427.00 € | ||
| 25mg | 689.00 € | ||
| 50mg | 920.00 € | ||
| 100mg | 1,268.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
