PI3K/Akt/mTOR Signaling
PI3K/Akt/mTOR signaling inhibitors are compounds that target the phosphoinositide 3-kinase (PI3K), Akt kinase, and mammalian target of rapamycin (mTOR) pathways. These pathways are critical regulators of cell growth, survival, metabolism, and autophagy, making them key targets in cancer research and metabolic disorders. Inhibiting these pathways can help to control tumor growth and proliferation, offering potential therapeutic strategies for various cancers and other diseases characterized by dysregulated cell signaling. At CymitQuimica, we offer a comprehensive selection of high-quality PI3K/Akt/mTOR inhibitors to support your research in oncology, cellular signaling, and metabolic diseases.
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Subcategories of "PI3K/Akt/mTOR Signaling"
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Products of "PI3K/Akt/mTOR Signaling"
KenPaullone
CAS:142273-20-9
KenPaullone (9-Bromopaullone), a potent CDK1, CDK2 and CDK5 inhibitor, as new enhancer for iTreg cell …
Formula:
C16H11BrN2O
Purity:
97.92% - 98.99%
Color and Shape:
Tan Solid
Molecular weight:
327.18
Ref: TM-T2247
| 1mg | 38.00 € | ||
| 2mg | 49.00 € | ||
| 5mg | 69.00 € | ||
| 10mg | 93.00 € | ||
| 25mg | 184.00 € | ||
| 50mg | 314.00 € | ||
| 100mg | 465.00 € | ||
| 500mg | 1,056.00 € | ||
| 1mL*10mM (DMSO) | 75.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
(S)-Afatinib
CAS:439081-18-2
(S)-Afatinib (BIBW2992) is an irreversible EGFR family inhibitor with IC50s of 0.5/0.4/10/14/1 nM for EGFRwt, …
Formula:
C24H25ClFN5O3
Purity:
100% - 99.96%
Color and Shape:
Off-White Solid
Molecular weight:
485.94
Ref: TM-T2303
| 1g | 64.00 € | ||
| 200mg | 36.00 € | ||
| 500mg | 50.00 € | ||
| 1mL*10mM (DMSO) | 34.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
WHI-P154
CAS:211555-04-3
WHI-P154 (Jak3 inhibitor ii) is a potent JAK3 inhibitor.
Formula:
C16H14BrN3O3
Purity:
98% - 99.6%
Color and Shape:
Solid
Molecular weight:
376.2
Ref: TM-T1985
| 2mg | 46.00 € | ||
| 5mg | 61.00 € | ||
| 10mg | 96.00 € | ||
| 25mg | 174.00 € | ||
| 50mg | 328.00 € | ||
| 100mg | 532.00 € | ||
| 1mL*10mM (DMSO) | 63.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
TX1-85-1
CAS:1603845-32-4
TX1-85-1: irreversible Her3 inhibitor (IC50: 23 nM), degrades Her3 protein, disrupts signaling, binds Cys721 covalently.
Formula:
C32H36N8O3
Purity:
98.12% - 98.12%
Color and Shape:
Solid
Molecular weight:
580.68
Ref: TM-T17182
| 1mg | 69.00 € | ||
| 5mg | 125.00 € | ||
| 10mg | 212.00 € | ||
| 25mg | 362.00 € | ||
| 50mg | 532.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Indirubin-3′-oxime
CAS:667463-82-3
Indirubin-3′-oxime is an effective inhibitor of cyclin-dependent protein kinases, and may play an obligate role …
Formula:
C16H11N3O2
Purity:
98.34%
Color and Shape:
Solid
Molecular weight:
277.28
Ref: TM-T9138
| 1mg | 46.00 € | ||
| 2mg | 40.00 € | ||
| 5mg | 96.00 € | ||
| 10mg | 145.00 € | ||
| 25mg | 275.00 € | ||
| 50mg | 424.00 € | ||
| 100mg | 625.00 € | ||
| 200mg | 520.00 € | ||
| 1mL*10mM (DMSO) | 121.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Osu03012
CAS:742112-33-0
Osu03012 (AR-12): oral celecoxib-derived PDK1 inhibitor with anticancer potential.
Formula:
C26H19F3N4O
Purity:
97.95% - 99.22%
Color and Shape:
Solid
Molecular weight:
460.45
Ref: TM-T2466
| 2mg | 37.00 € | ||
| 5mg | 51.00 € | ||
| 10mg | 85.00 € | ||
| 25mg | 141.00 € | ||
| 50mg | 259.00 € | ||
| 100mg | 341.00 € | ||
| 200mg | 445.00 € | ||
| 500mg | 729.00 € | ||
| 1mL*10mM (DMSO) | 52.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
TAS0728
CAS:2088323-16-2
TAS0728 is a HER2 inhibitor, with antitumor activity
Formula:
C26H32N8O3
Purity:
97.78%
Color and Shape:
Solid
Molecular weight:
504.58
Ref: TM-T7819
| 1mg | 50.00 € | ||
| 5mg | 107.00 € | ||
| 10mg | 169.00 € | ||
| 25mg | 310.00 € | ||
| 50mg | 493.00 € | ||
| 100mg | 670.00 € | ||
| 200mg | 902.00 € | ||
| 1mL*10mM (DMSO) | 113.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
NRC-2694
CAS:936446-61-6
NRC-2694 is an antagonist of the epidermal growth factor receptor (EGFR). It has anti-cancer and …
Formula:
C24H26N4O3
Purity:
99.38%
Color and Shape:
Solid
Molecular weight:
418.49
Ref: TM-T16343
| 1mg | 82.00 € | ||
| 5mg | 155.00 € | ||
| 10mg | 241.00 € | ||
| 25mg | 409.00 € | ||
| 50mg | 542.00 € | ||
| 100mg | 780.00 € | ||
| 200mg | 1,034.00 € | ||
| 1mL*10mM (DMSO) | 170.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Theliatinib
CAS:1353644-70-8
Theliatinib: potent, selective EGFR inhibitor, anti-tumor; Ki=0.05 nM (EGFR), IC50=3 nM (EGFR), 22 nM (T790M/L858R).
Formula:
C25H26N6O2
Purity:
99.67%
Color and Shape:
Solid
Molecular weight:
442.51
Ref: TM-T7322
| 1mg | 52.00 € | ||
| 5mg | 142.00 € | ||
| 10mg | 222.00 € | ||
| 25mg | 368.00 € | ||
| 50mg | 553.00 € | ||
| 100mg | 757.00 € | ||
| 1mL*10mM (DMSO) | 156.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Tucatinib
CAS:937263-43-9
Tucatinib (ONT-380) is a potent and selective HER2 inhibitor (IC50: 8 nM).
Formula:
C26H24N8O2
Purity:
99.05% - 99.96%
Color and Shape:
Solid
Molecular weight:
480.52
Ref: TM-T2364
| 1g | 1,110.00 € | ||
| 2mg | 40.00 € | ||
| 5mg | 54.00 € | ||
| 10mg | 83.00 € | ||
| 25mg | 127.00 € | ||
| 50mg | 189.00 € | ||
| 100mg | 343.00 € | ||
| 500mg | 812.00 € | ||
| 1mL*10mM (DMSO) | 87.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
PI-103
CAS:371935-74-9
PI-103 is a potent, cell-permeable, ATP-competitive inhibitor of PI3K family members (IC50s: 2/3/3/15/30/23 nM for …
Formula:
C19H16N4O3
Purity:
96.59% - 99.3%
Color and Shape:
Solid
Molecular weight:
348.36
Ref: TM-T6143
| 5mg | 58.00 € | ||
| 10mg | 71.00 € | ||
| 25mg | 125.00 € | ||
| 50mg | 197.00 € | ||
| 100mg | 363.00 € | ||
| 200mg | 553.00 € | ||
| 1mL*10mM (DMSO) | 60.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
20(S)-Ginsenoside Rg3
CAS:14197-60-5
20(S)-Ginsenoside Rg3 (Rg3) possess an ability to inhibit the lung metastasis of tumor cells via …
Formula:
C42H72O13
Purity:
100% - 99.53%
Color and Shape:
Solid
Molecular weight:
785.01
Ref: TM-T3402
| 5mg | 38.00 € | ||
| 10mg | 56.00 € | ||
| 25mg | 84.00 € | ||
| 50mg | 95.00 € | ||
| 100mg | 167.00 € | ||
| 1mL*10mM (DMSO) | 64.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
(E)-AG 99
CAS:122520-85-8
(E)-AG 99 ((E)-Tyrphostin AG 99) is an inhibitor of EGFR kinase (IC50: 10 μM in …
Formula:
C10H8N2O3
Purity:
99.23%
Color and Shape:
Solid
Molecular weight:
204.18
Ref: TM-T5155
| 5mg | 35.00 € | ||
| 10mg | 51.00 € | ||
| 25mg | 79.00 € | ||
| 50mg | 94.00 € | ||
| 100mg | 157.00 € | ||
| 1mL*10mM (DMSO) | 57.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
ZD-4190
CAS:413599-62-9
ZD-4190 blocks VEGFR2 and EGFR, aiding cancer treatment.
Formula:
C19H16BrFN6O2
Purity:
99.12%
Color and Shape:
Solid
Molecular weight:
459.27
Ref: TM-T5475
| 1mg | 82.00 € | ||
| 5mg | 177.00 € | ||
| 10mg | 266.00 € | ||
| 25mg | 422.00 € | ||
| 50mg | 577.00 € | ||
| 100mg | 780.00 € | ||
| 200mg | 1,034.00 € | ||
| 1mL*10mM (DMSO) | 179.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
PIK-108
CAS:901398-68-3
PIK-108 is an allosteric inhibitor of phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunits β and δ (PI3Kβ/δ).
Formula:
C22H24N2O3
Purity:
98.92%
Color and Shape:
Solid
Molecular weight:
364.44
Ref: TM-T28416
| 1mg | 39.00 € | ||
| 2mg | 55.00 € | ||
| 5mg | 93.00 € | ||
| 10mg | 150.00 € | ||
| 25mg | 246.00 € | ||
| 50mg | 355.00 € | ||
| 100mg | 491.00 € | ||
| 200mg | 674.00 € | ||
| 1mL*10mM (DMSO) | 102.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
MOMIPP
CAS:1363421-46-8
MOMIPP: PIKfyve inhibitor, spurs macropinocytosis, crosses blood-brain barrier, curbs glioblastoma growth.
Formula:
C18H16N2O2
Purity:
99.66%
Color and Shape:
Solid
Molecular weight:
292.33
Ref: TM-T33467
| 1mg | 112.00 € | ||
| 5mg | 154.00 € | ||
| 10mg | 241.00 € | ||
| 25mg | 438.00 € | ||
| 50mg | 605.00 € | ||
| 100mg | 907.00 € | ||
| 1mL*10mM (DMSO) | 243.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
JCN037
CAS:2305154-31-6
JCN037 is potent, non-covalent and brain-penetrant inhibitor of EGFR(EGFR, p-wtEGFR and pEGFRvⅢ with IC50 of …
Formula:
C16H11BrFN3O2
Purity:
99.50%
Color and Shape:
Solid
Molecular weight:
376.18
Ref: TM-T8431
| 2mg | 39.00 € | ||
| 5mg | 72.00 € | ||
| 10mg | 102.00 € | ||
| 25mg | 172.00 € | ||
| 50mg | 263.00 € | ||
| 100mg | 377.00 € | ||
| 200mg | 537.00 € | ||
| 1mL*10mM (DMSO) | 81.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Mutant EGFR inhibitor
CAS:1421373-62-7
Selective, potent inhibitor for mutated EGFR: L858R, Exon19 deletion, T790M resistance mutants.
Formula:
C27H30ClN7O2
Purity:
96.21% - 98%
Color and Shape:
Solid
Molecular weight:
520.03
Ref: TM-T2705
| 1mg | 36.00 € | ||
| 2mg | 52.00 € | ||
| 5mg | 79.00 € | ||
| 10mg | 95.00 € | ||
| 25mg | 170.00 € | ||
| 50mg | 258.00 € | ||
| 100mg | 371.00 € | ||
| 500mg | To inquire | ||
| 1mL*10mM (DMSO) | 104.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
KU-0063794
CAS:938440-64-3
KU-0063794 is a potent and highly specific dual-mTOR inhibitor of mTORC1 and mTORC2.
Formula:
C25H31N5O4
Purity:
100% - 98.35%
Color and Shape:
Solid
Molecular weight:
465.54
Ref: TM-T2475
| 5mg | 61.00 € | ||
| 10mg | 83.00 € | ||
| 25mg | 127.00 € | ||
| 50mg | 222.00 € | ||
| 100mg | 407.00 € | ||
| 500mg | 918.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Biochanin A
CAS:491-80-5
Biochanin A: an isoflavone from red clover with anticancer properties and inhibits FAAH.
Formula:
C16H12O5
Purity:
97.1% - 97.69%
Color and Shape:
Solid
Molecular weight:
284.26
Ref: TM-T2859
| 100mg | 40.00 € | ||
| 200mg | 55.00 € | ||
| 500mg | 94.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
