PI3K/Akt/mTOR Signaling
PI3K/Akt/mTOR signaling inhibitors are compounds that target the phosphoinositide 3-kinase (PI3K), Akt kinase, and mammalian target of rapamycin (mTOR) pathways. These pathways are critical regulators of cell growth, survival, metabolism, and autophagy, making them key targets in cancer research and metabolic disorders. Inhibiting these pathways can help to control tumor growth and proliferation, offering potential therapeutic strategies for various cancers and other diseases characterized by dysregulated cell signaling. At CymitQuimica, we offer a comprehensive selection of high-quality PI3K/Akt/mTOR inhibitors to support your research in oncology, cellular signaling, and metabolic diseases.
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Subcategories of "PI3K/Akt/mTOR Signaling"
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Products of "PI3K/Akt/mTOR Signaling"
AZD-8835
CAS:1620576-64-8
AZD-8835 is a mixed inhibitor of PI3Kα/δ (IC50: 6.2/5.7 nM), also with selectivity against PI3Kβ/γ …
Formula:
C22H31N9O3
Purity:
98.22% - 98.49%
Color and Shape:
Solid
Molecular weight:
469.54
Ref: TM-T6774
| 5mg | 50.00 € | ||
| 10mg | 68.00 € | ||
| 25mg | 114.00 € | ||
| 50mg | 166.00 € | ||
| 100mg | 293.00 € | ||
| 1mL*10mM (DMSO) | 56.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
AS-604850
CAS:648449-76-7
AS-604850: ATP-competitive PI3Kγ inhibitor, IC50 250 nM, 18x >PI3Kα, 80x > PI3Kδ/β.
Formula:
C11H5F2NO4S
Purity:
99.84%
Color and Shape:
Solid
Molecular weight:
285.22
Ref: TM-T6394
| 10mg | 50.00 € | ||
| 25mg | 78.00 € | ||
| 50mg | 113.00 € | ||
| 100mg | 203.00 € | ||
| 200mg | 301.00 € | ||
| 1mL*10mM (DMSO) | 37.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Tyrphostin A1
CAS:2826-26-8
Tyrphostin A1 (Tyrphostin 1) is an inhibitor of EGFR tyrosine kinase .
Formula:
C11H8N2O
Purity:
99.13%
Color and Shape:
Solid
Molecular weight:
184.19
Ref: TM-T7649
| 10mg | 35.00 € | ||
| 25mg | 57.00 € | ||
| 50mg | 81.00 € | ||
| 100mg | 93.00 € | ||
| 200mg | 136.00 € | ||
| 1mL*10mM (DMSO) | 34.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
CH5132799
CAS:1007207-67-1
CH5132799 has been used in trials studying the treatment of Solid Tumors.
Formula:
C15H19N7O3S
Purity:
98.81% - 99.87%
Color and Shape:
Solid
Molecular weight:
377.42
Ref: TM-T2619
| 1mg | 63.00 € | ||
| 2mg | 96.00 € | ||
| 5mg | 143.00 € | ||
| 10mg | 225.00 € | ||
| 25mg | 416.00 € | ||
| 50mg | 615.00 € | ||
| 100mg | 874.00 € | ||
| 500mg | 1,746.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Seletalisib
CAS:1362850-20-1
Seletalisib (UCB5857) (UCB5857) is a potent and specific PI3Kδ inhibitor (IC50: 12 nM).
Formula:
C23H14ClF3N6O
Purity:
99.81%
Color and Shape:
Solid
Molecular weight:
482.85
Ref: TM-TQ0044
| 1mg | 57.00 € | ||
| 2mg | 81.00 € | ||
| 5mg | 120.00 € | ||
| 10mg | 187.00 € | ||
| 25mg | 328.00 € | ||
| 50mg | 468.00 € | ||
| 100mg | 656.00 € | ||
| 1mL*10mM (DMSO) | 125.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
GSK2636771
CAS:1372540-25-4
GSK2636771, an effective, specific, orally bioavailable, PI3Kβ inhibitor, has been used in cancer, lymphoma, solid …
Formula:
C22H22F3N3O3
Purity:
98.58% - ≥95%
Color and Shape:
Solid
Molecular weight:
433.42
Ref: TM-T2073
| 1mg | 42.00 € | ||
| 2mg | 56.00 € | ||
| 5mg | 87.00 € | ||
| 10mg | 147.00 € | ||
| 25mg | 248.00 € | ||
| 50mg | 353.00 € | ||
| 100mg | 535.00 € | ||
| 1mL*10mM (DMSO) | 89.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
WZ4002
CAS:1213269-23-8
WZ4002 is a mutant-selective EGFR inhibitor for EGFR(L858R) and EGFR(T790M) with IC50 of 2 nM/8 …
Formula:
C25H27ClN6O3
Purity:
98.12%
Color and Shape:
Solid
Molecular weight:
494.97
Ref: TM-T6238
| 2mg | 35.00 € | ||
| 5mg | 51.00 € | ||
| 10mg | 72.00 € | ||
| 25mg | 115.00 € | ||
| 50mg | 183.00 € | ||
| 100mg | 325.00 € | ||
| 200mg | 478.00 € | ||
| 1mL*10mM (DMSO) | 53.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Vps34-IN-1
CAS:1383716-33-3
Vps34-IN-1: potent, selective Vps34 inhibitor, 25 nM IC50, spares class I/II PI3Ks.
Formula:
C21H24ClN7O
Purity:
97.04%
Color and Shape:
Solid
Molecular weight:
425.91
Ref: TM-T7015
| 1mg | 45.00 € | ||
| 2mg | 59.00 € | ||
| 5mg | 91.00 € | ||
| 10mg | 128.00 € | ||
| 25mg | 215.00 € | ||
| 50mg | 344.00 € | ||
| 100mg | 493.00 € | ||
| 1mL*10mM (DMSO) | 91.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
SAR405
CAS:1523406-39-4
SAR-405 inhibits PIK3C3/Vps34 (IC50: 1.2 nM, Kd: 1.5 nM), blocks autophagy, and enhances MTOR inhibitor …
Formula:
C19H21ClF3N5O2
Purity:
99.42% - 99.79%
Color and Shape:
Solid
Molecular weight:
443.85
Ref: TM-T12831L
| 1mg | 52.00 € | ||
| 2mg | 78.00 € | ||
| 5mg | 102.00 € | ||
| 10mg | 177.00 € | ||
| 25mg | 351.00 € | ||
| 50mg | 547.00 € | ||
| 1mL*10mM (DMSO) | 96.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
PIK-90
CAS:677338-12-4
PIK-90, a DNA-PK and PI3K inhibitor, suppresses p110α( IC50=11 nM), p110γ(IC50=18 nM) and DNA-PK(IC50=13 nM) …
Formula:
C18H17N5O3
Purity:
98.25% - ≥95%
Color and Shape:
Solid
Molecular weight:
351.36
Ref: TM-T2461
| 5mg | 46.00 € | ||
| 10mg | 51.00 € | ||
| 25mg | 92.00 € | ||
| 50mg | 142.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
A66
CAS:1166227-08-2
A66 is a specific and effective p110α inhibitor(IC50=32 nM).
Formula:
C17H23N5O2S2
Purity:
99.51% - ≥95%
Color and Shape:
Solid
Molecular weight:
393.53
Ref: TM-T2418
| 2mg | 35.00 € | ||
| 5mg | 50.00 € | ||
| 10mg | 81.00 € | ||
| 25mg | 141.00 € | ||
| 50mg | 240.00 € | ||
| 100mg | 354.00 € | ||
| 200mg | 497.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Linperlisib
CAS:1702816-75-8
Linperlisib (PI3Kδ-IN-2) is a potent and selective inhibitor of PI3Kδ
Formula:
C28H37FN6O5S
Purity:
99.01%
Color and Shape:
Solid
Molecular weight:
588.69
Ref: TM-T6330
| 1mg | 35.00 € | ||
| 2mg | 47.00 € | ||
| 5mg | 69.00 € | ||
| 10mg | 94.00 € | ||
| 25mg | 199.00 € | ||
| 50mg | 305.00 € | ||
| 100mg | 477.00 € | ||
| 1mL*10mM (DMSO) | 92.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
VPS34 inhibitor 1 (Compound 19, PIK-III analogue)
CAS:1383716-46-8
VPS34 inhibitor 1 (Compound 19, PIK-III analogue) (PIK-III analogue) is a potent and selective inhibitor …
Formula:
C21H25N7O
Purity:
98.60%
Color and Shape:
Solid
Molecular weight:
391.47
Ref: TM-T7944
| 1mg | 66.00 € | ||
| 5mg | 141.00 € | ||
| 10mg | 222.00 € | ||
| 25mg | 389.00 € | ||
| 50mg | 553.00 € | ||
| 100mg | 735.00 € | ||
| 1mL*10mM (DMSO) | 185.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
AG490
CAS:133550-30-8
AG490 inhibits EGFR (0.1 μM IC50), 135x >selective than ErbB2, blocks JAK2, spares Lyn, Lck, …
Formula:
C17H14N2O3
Purity:
98.6% - 99.7%
Color and Shape:
Yellow Solid
Molecular weight:
294.3
Ref: TM-T2600
| 10mg | 55.00 € | ||
| 25mg | 74.00 € | ||
| 50mg | 90.00 € | ||
| 100mg | 100.00 € | ||
| 200mg | 162.00 € | ||
| 500mg | 278.00 € | ||
| 1mL*10mM (DMSO) | 53.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Torin 1
CAS:1222998-36-8
Torin 1 is an effective inhibitor of mTORC1/2 with (IC50: 2 nM/10 nM); has 1000-fold …
Formula:
C35H28F3N5O2
Purity:
98.3% - 99.38%
Color and Shape:
Solid
Molecular weight:
607.62
Ref: TM-T6045
| 1mg | 36.00 € | ||
| 2mg | 48.00 € | ||
| 5mg | 72.00 € | ||
| 10mg | 94.00 € | ||
| 25mg | 170.00 € | ||
| 50mg | 305.00 € | ||
| 100mg | 471.00 € | ||
| 500mg | 1,015.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Afzelin
CAS:482-39-3
Afzelin (Kaempferol-3-O-rhamnoside) has several cellular activities such as DNA-protective, antibacterial, antioxidant, and anti-inflammatory as well …
Formula:
C21H20O10
Purity:
99.38%
Color and Shape:
Solid
Molecular weight:
432.38
Ref: TM-TN1362
| 1mg | 47.00 € | ||
| 5mg | 121.00 € | ||
| 10mg | 173.00 € | ||
| 25mg | 289.00 € | ||
| 50mg | 429.00 € | ||
| 100mg | 628.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
AG-494
CAS:133550-35-3
AG-494 (Tyrphostin B48) is an inhibitor of epidermal growth factor receptor kinase.
Formula:
C16H12N2O3
Purity:
98.9%
Color and Shape:
Solid
Molecular weight:
280.28
Ref: TM-T4205
| 5mg | 41.00 € | ||
| 10mg | 66.00 € | ||
| 25mg | 120.00 € | ||
| 50mg | 184.00 € | ||
| 100mg | 323.00 € | ||
| 1mL*10mM (DMSO) | 47.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
AZD8931 diFuMaric acid
CAS:1196531-39-1
AZD8931 is a reversible and ATP competitive inhibitor of EGFR, ErbB2 and ErbB3 (IC50 of …
Formula:
C31H33ClFN5O11
Purity:
99%
Color and Shape:
Solid
Molecular weight:
706.1
Ref: TM-T8751
| 1mg | 85.00 € | ||
| 5mg | 172.00 € | ||
| 10mg | 249.00 € | ||
| 25mg | 410.00 € | ||
| 50mg | 577.00 € | ||
| 100mg | 780.00 € | ||
| 200mg | 1,034.00 € | ||
| 1mL*10mM (DMSO) | 247.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Neratinib
CAS:698387-09-6
Neratinib (HKI-272) (HKI-272) is an orally available, irreversible tyrosine kinase inhibitor for HER2 and EGFR …
Formula:
C30H29ClN6O3
Purity:
100% - 98.55%
Color and Shape:
Solid
Molecular weight:
557.04
Ref: TM-T2325
| 5mg | 35.00 € | ||
| 10mg | 51.00 € | ||
| 25mg | 69.00 € | ||
| 50mg | 92.00 € | ||
| 100mg | 122.00 € | ||
| 200mg | 184.00 € | ||
| 500mg | 307.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
PF-6274484
CAS:1035638-91-5
PF-6274484 is an EGFR inhibitor with Ki values of 0.14 and 0.18 nM for EGFR-L858R/T790M …
Formula:
C18H14ClFN4O2
Purity:
97.71%
Color and Shape:
Solid
Molecular weight:
372.78
Ref: TM-T22396
| 2mg | 40.00 € | ||
| 5mg | 60.00 € | ||
| 10mg | 90.00 € | ||
| 25mg | 184.00 € | ||
| 50mg | 343.00 € | ||
| 100mg | 510.00 € | ||
| 500mg | 1,112.00 € | ||
| 1mL*10mM (DMSO) | 67.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
