PI3K/Akt/mTOR Signaling
PI3K/Akt/mTOR signaling inhibitors are compounds that target the phosphoinositide 3-kinase (PI3K), Akt kinase, and mammalian target of rapamycin (mTOR) pathways. These pathways are critical regulators of cell growth, survival, metabolism, and autophagy, making them key targets in cancer research and metabolic disorders. Inhibiting these pathways can help to control tumor growth and proliferation, offering potential therapeutic strategies for various cancers and other diseases characterized by dysregulated cell signaling. At CymitQuimica, we offer a comprehensive selection of high-quality PI3K/Akt/mTOR inhibitors to support your research in oncology, cellular signaling, and metabolic diseases.
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Subcategories of "PI3K/Akt/mTOR Signaling"
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Products of "PI3K/Akt/mTOR Signaling"
AZD8186
CAS:1627494-13-6
AZD8186 is an effective and specific PI3Kβ/δ inhibitor (IC50: 4/12 nM).
Formula:
C24H25F2N3O4
Purity:
99.89% - 99.91%
Color and Shape:
Solid
Molecular weight:
457.47
Ref: TM-T6773
| 2mg | 45.00 € | ||
| 5mg | 66.00 € | ||
| 10mg | 98.00 € | ||
| 25mg | 172.00 € | ||
| 50mg | 301.00 € | ||
| 100mg | 498.00 € | ||
| 500mg | 1,096.00 € | ||
| 1mL*10mM (DMSO) | 72.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Zotarolimus
CAS:221877-54-9
Zotarolimus (ABT-578), an analogue of rapamycin, inhibits FKBP-12 (IC50= 2.8 nM).
Formula:
C52H79N5O12
Purity:
95% - ≥98%
Color and Shape:
Solid
Molecular weight:
966.21
Ref: TM-T6033
| 1mg | 65.00 € | ||
| 2mg | 95.00 € | ||
| 5mg | 142.00 € | ||
| 10mg | 220.00 € | ||
| 25mg | 385.00 € | ||
| 50mg | 555.00 € | ||
| 100mg | 800.00 € | ||
| 1mL*10mM (DMSO) | 237.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
DMNB
CAS:20357-25-9
DMNB (6-Nitroveratraldehyde) is DNA-dependent protein kinase (DNA-PK) inhibitor, an enzyme involved in the NHEJ pathway …
Formula:
C9H9NO5
Purity:
≥98%
Color and Shape:
Yellow Solid
Molecular weight:
211.17
Ref: TM-T8637
| 200mg | 34.00 € | ||
| 1mL*10mM (DMSO) | 45.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Allitinib tosylate
CAS:1050500-29-2
Allitinib tosylate (AST-1306) is a novel irreversible inhibitor of EGFR and ErbB2 with IC50 of …
Formula:
C31H26ClFN4O5S
Purity:
98.46% - 98.52%
Color and Shape:
Solid
Molecular weight:
621.08
Ref: TM-T6331
| 1mg | 52.00 € | ||
| 5mg | 110.00 € | ||
| 10mg | 174.00 € | ||
| 25mg | 326.00 € | ||
| 50mg | 487.00 € | ||
| 100mg | 692.00 € | ||
| 1mL*10mM (DMSO) | 153.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Avitinib
CAS:1557267-42-1
Avitinib (AC0010), also known as AC0010 or AC0010MA, is an orally available, irreversible, epidermal growth …
Formula:
C26H26FN7O2
Purity:
100%
Color and Shape:
Solid
Molecular weight:
487.53
Ref: TM-T3024
| 2mg | 48.00 € | ||
| 5mg | 73.00 € | ||
| 10mg | 113.00 € | ||
| 25mg | 212.00 € | ||
| 50mg | 347.00 € | ||
| 100mg | 513.00 € | ||
| 1mL*10mM (DMSO) | 87.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
CZ415
CAS:1429639-50-8
CZ415 is a potent and highly selective mTOR inhibitor.
Formula:
C22H29N5O4S
Purity:
98.36% - 98.44%
Color and Shape:
Solid
Molecular weight:
459.56
Ref: TM-T3514
| 1mg | 41.00 € | ||
| 2mg | 50.00 € | ||
| 5mg | 72.00 € | ||
| 10mg | 106.00 € | ||
| 25mg | 215.00 € | ||
| 50mg | 325.00 € | ||
| 100mg | 454.00 € | ||
| 200mg | 629.00 € | ||
| 1mL*10mM (DMSO) | 73.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
GNF4877
CAS:2041073-22-5
GNF4877 inhibits DYRK1A/GSK3β (IC50: 6/16 nM), blocks NFATc export, and boosts β-cell growth.
Formula:
C25H27FN6O4
Purity:
98.63% - 99.40%
Color and Shape:
Solid
Molecular weight:
494.52
Ref: TM-T11447
| 1mg | 123.00 € | ||
| 5mg | 291.00 € | ||
| 10mg | 507.00 € | ||
| 25mg | 921.00 € | ||
| 50mg | 1,278.00 € | ||
| 100mg | 1,725.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
VS-5584
CAS:1246560-33-7
VS-5584 (SB2343) is a pan-PI3K/mTOR kinase inhibitor.
Formula:
C17H22N8O
Purity:
97.82% - 99.54%
Color and Shape:
Solid
Molecular weight:
354.41
Ref: TM-T6103
| 5mg | 37.00 € | ||
| 10mg | 61.00 € | ||
| 25mg | 96.00 € | ||
| 50mg | 135.00 € | ||
| 100mg | 186.00 € | ||
| 200mg | 279.00 € | ||
| 1mL*10mM (DMSO) | 42.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
(E/Z)-GSK-3β inhibitor 1
CAS:3367-88-2
(E/Z)-GSK-3β inhibitor 1 is a glycogen synthase kinase 3β (GSK-3β) inhibitor and demonstrates high antidiabetic …
Formula:
C14H10N2O
Purity:
99.8%
Color and Shape:
Solid
Molecular weight:
222.24
Ref: TM-T9178
| 1mg | 37.00 € | ||
| 5mg | 82.00 € | ||
| 10mg | 122.00 € | ||
| 25mg | 217.00 € | ||
| 50mg | 324.00 € | ||
| 100mg | 464.00 € | ||
| 200mg | 630.00 € | ||
| 1mL*10mM (DMSO) | 91.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
ETP-46321
CAS:1252594-99-2
ETP-46321 is an effective and orally bioavailable PI3Kα/PI3Kδ inhibitor (Ki: 2.3/14.2 nM).
Formula:
C20H27N9O3S
Purity:
99.80%
Color and Shape:
Solid
Molecular weight:
473.55
Ref: TM-TQ0229
| 1mg | 50.00 € | ||
| 5mg | 107.00 € | ||
| 10mg | 169.00 € | ||
| 25mg | 309.00 € | ||
| 50mg | 432.00 € | ||
| 100mg | 593.00 € | ||
| 200mg | 803.00 € | ||
| 1mL*10mM (DMSO) | 113.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
CP-380736
CAS:179688-29-0
CP-380736 (PF-00520893) inhibits EGFR, a kinase key in cancer-signaling pathways like MAPK, JNK, and Akt.
Formula:
C14H18N2O5
Purity:
99.91%
Color and Shape:
White To Off-White Solid
Molecular weight:
294.3
Ref: TM-T19814
| 5mg | 34.00 € | ||
| 10mg | 52.00 € | ||
| 25mg | 82.00 € | ||
| 50mg | 109.00 € | ||
| 100mg | 163.00 € | ||
| 200mg | 237.00 € | ||
| 1mL*10mM (DMSO) | 45.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
AZ-5104
CAS:1421373-98-9
AZ5104 is a potent EGFR inhibitor.
Formula:
C27H31N7O2
Purity:
98.45% - 99.9%
Color and Shape:
Solid Powder
Molecular weight:
485.58
Ref: TM-T2491
| 5mg | 57.00 € | ||
| 10mg | 79.00 € | ||
| 25mg | 126.00 € | ||
| 50mg | 188.00 € | ||
| 100mg | 251.00 € | ||
| 200mg | 314.00 € | ||
| 1mL*10mM (DMSO) | 58.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Autophinib
CAS:1644443-47-9
Autophinib is a potent autophagy inhibitor with a novel chemotype with IC50 values of 90 …
Formula:
C14H11ClN6O3
Purity:
98.83% - 99.41%
Color and Shape:
Solid
Molecular weight:
346.73
Ref: TM-T4219
| 1mg | 35.00 € | ||
| 2mg | 51.00 € | ||
| 5mg | 75.00 € | ||
| 10mg | 100.00 € | ||
| 25mg | 171.00 € | ||
| 50mg | 274.00 € | ||
| 100mg | 427.00 € | ||
| 200mg | 357.00 € | ||
| 500mg | 916.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
KU-57788
CAS:503468-95-9
NU7441 (KU-57788 (NU7441)) is a highly effective and specific DNA-PK inhibitor (IC50: 14 nM).
Formula:
C25H19NO3S
Purity:
100% - 99.87%
Color and Shape:
Solid
Molecular weight:
413.49
Ref: TM-T6276
| 2mg | 40.00 € | ||
| 5mg | 58.00 € | ||
| 10mg | 87.00 € | ||
| 25mg | 169.00 € | ||
| 50mg | 276.00 € | ||
| 100mg | 386.00 € | ||
| 500mg | 909.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Torin 2
CAS:1223001-51-1
Torin 2: mTOR inhibitor, IC50=0.25 nM, 800x more selective than PI3K, with EC50=28/35/118 nM for …
Formula:
C24H15F3N4O
Purity:
98.31% - 99.32%
Color and Shape:
Solid
Molecular weight:
432.4
Ref: TM-T6100
| 2mg | 41.00 € | ||
| 5mg | 60.00 € | ||
| 10mg | 90.00 € | ||
| 25mg | 163.00 € | ||
| 50mg | 252.00 € | ||
| 100mg | 375.00 € | ||
| 200mg | 557.00 € | ||
| 500mg | 885.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Dacomitinib
CAS:1110813-31-4
Dacomitinib (PF299) is an oral selective inhibitor of EGFR, ERBB2, ERBB4 with IC50s: 6, 45.7, …
Formula:
C24H25ClFN5O2
Purity:
100% - 99.34%
Color and Shape:
Solid
Molecular weight:
469.94
Ref: TM-T2483
| 1mg | 38.00 € | ||
| 2mg | 49.00 € | ||
| 5mg | 78.00 € | ||
| 10mg | 124.00 € | ||
| 25mg | 170.00 € | ||
| 50mg | 222.00 € | ||
| 100mg | 348.00 € | ||
| 200mg | 435.00 € | ||
| 500mg | 717.00 € | ||
| 1mL*10mM (DMSO) | 79.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Taselisib
CAS:1282512-48-4
Taselisib (GDC-0032) is an oral PI3K alpha inhibitor with potential cancer-treating properties.
Formula:
C24H28N8O2
Purity:
98.92% - 99.62%
Color and Shape:
Solid
Molecular weight:
460.53
Ref: TM-T1999
| 2mg | 45.00 € | ||
| 5mg | 66.00 € | ||
| 10mg | 90.00 € | ||
| 25mg | 154.00 € | ||
| 50mg | 194.00 € | ||
| 100mg | 343.00 € | ||
| 200mg | 513.00 € | ||
| 500mg | 827.00 € | ||
| 1mL*10mM (DMSO) | 67.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Poziotinib hydrochloride
CAS:1429757-68-5
Oral poziotinib HCl targets EGFR/HER mutants, inhibiting cancer cell growth.
Formula:
C23H22Cl3FN4O3
Purity:
97.48% - 99.69%
Color and Shape:
Solid
Molecular weight:
527.8
Ref: TM-T8758
| 5mg | 55.00 € | ||
| 10mg | 82.00 € | ||
| 25mg | 125.00 € | ||
| 50mg | 181.00 € | ||
| 100mg | 270.00 € | ||
| 200mg | 405.00 € | ||
| 500mg | 666.00 € | ||
| 1mL*10mM (DMSO) | 88.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Leniolisib
CAS:1354690-24-6
Leniolisib (CDZ173) (CDZ173) is a potent and selective PI3Kδ inhibitor (IC50: 11 nM).
Formula:
C21H25F3N6O2
Purity:
99.88%
Color and Shape:
Solid
Molecular weight:
450.46
Ref: TM-T5166
| 1mg | 78.00 € | ||
| 5mg | 151.00 € | ||
| 10mg | 219.00 € | ||
| 25mg | 411.00 € | ||
| 50mg | 639.00 € | ||
| 100mg | 924.00 € | ||
| 1mL*10mM (DMSO) | 164.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
ARN-3236
CAS:1613710-01-2
ARN-3236 is an oral active and selective inhibitor of salt-inducible kinase 2 (SIK2), (SIK2, SIK1 …
Formula:
C19H16N2O2S
Purity:
99.57% - 99.7%
Color and Shape:
Solid
Molecular weight:
336.41
Ref: TM-T5993
| 1mg | 59.00 € | ||
| 2mg | 85.00 € | ||
| 5mg | 122.00 € | ||
| 10mg | 179.00 € | ||
| 25mg | 337.00 € | ||
| 50mg | 420.00 € | ||
| 100mg | 648.00 € | ||
| 200mg | 916.00 € | ||
| 500mg | 1,356.00 € | ||
| 1mL*10mM (DMSO) | 150.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
