PI3K/Akt/mTOR Signaling
PI3K/Akt/mTOR signaling inhibitors are compounds that target the phosphoinositide 3-kinase (PI3K), Akt kinase, and mammalian target of rapamycin (mTOR) pathways. These pathways are critical regulators of cell growth, survival, metabolism, and autophagy, making them key targets in cancer research and metabolic disorders. Inhibiting these pathways can help to control tumor growth and proliferation, offering potential therapeutic strategies for various cancers and other diseases characterized by dysregulated cell signaling. At CymitQuimica, we offer a comprehensive selection of high-quality PI3K/Akt/mTOR inhibitors to support your research in oncology, cellular signaling, and metabolic diseases.
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Subcategories of "PI3K/Akt/mTOR Signaling"
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Products of "PI3K/Akt/mTOR Signaling"
TGX-221
CAS:663619-89-4
TGX-221, an effective, specific, and cell membrane permeable inhibitor of the PI3K p110β catalytic subunit, …
Formula:
C21H24N4O2
Purity:
100% - 99.8%
Color and Shape:
Solid
Molecular weight:
364.44
Ref: TM-T2661
| 1mg | 38.00 € | ||
| 2mg | 49.00 € | ||
| 5mg | 73.00 € | ||
| 10mg | 114.00 € | ||
| 25mg | 213.00 € | ||
| 50mg | 351.00 € | ||
| 100mg | 551.00 € | ||
| 500mg | 1,177.00 € | ||
| 1mL*10mM (DMSO) | 81.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Osimertinib
CAS:1421373-65-0
Osimertinib (AZD-9291) is a small molecule tyrosine kinase receptor inhibitor and antineoplastic agent that is …
Formula:
C28H33N7O2
Purity:
100% - 99.83%
Color and Shape:
Solid
Molecular weight:
499.61
Ref: TM-T2490
| 1g | 153.00 € | ||
| 2mg | 38.00 € | ||
| 5mg | 53.00 € | ||
| 10mg | 61.00 € | ||
| 25mg | 75.00 € | ||
| 50mg | 89.00 € | ||
| 100mg | 103.00 € | ||
| 200mg | 115.00 € | ||
| 500mg | 126.00 € | ||
| 1mL*10mM (DMSO) | 53.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
BQR-695
CAS:1513879-21-4
BQR-695 (NVP-BQR695) is a PI4K inhibitor with IC50s of 80 and 3.5 nM for human …
Formula:
C19H20N4O3
Purity:
100% - 97.16%
Color and Shape:
Solid
Molecular weight:
352.39
Ref: TM-T4220
| 5mg | 70.00 € | ||
| 10mg | 87.00 € | ||
| 25mg | 185.00 € | ||
| 50mg | 271.00 € | ||
| 100mg | 427.00 € | ||
| 500mg | 917.00 € | ||
| 1mL*10mM (DMSO) | 76.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
AZD1080
CAS:612487-72-6
AZD1080 is a selective, orally active, brain permeable GSK3 inhibitor.
Formula:
C19H18N4O2
Purity:
97.72% - 99.68%
Color and Shape:
Solid
Molecular weight:
334.37
Ref: TM-T1741
| 1mg | 42.00 € | ||
| 2mg | 55.00 € | ||
| 5mg | 83.00 € | ||
| 10mg | 122.00 € | ||
| 25mg | 215.00 € | ||
| 50mg | 344.00 € | ||
| 100mg | 421.00 € | ||
| 1mL*10mM (DMSO) | 63.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
EGFR/ErbB-2/ErbB-4 inhibitor-2
CAS:179248-61-4
EGFR/ErbB-2/ErbB-4 inhibitor-2 (EGFR/ErbB2 Inhibitor) is a cell-permeable inhibitor of EGFR and c-ErbB2 (IC50s = 20 …
Formula:
C23H21N3O3
Purity:
99.55%
Color and Shape:
Solid
Molecular weight:
387.43
Ref: TM-T21954
| 1mg | 73.00 € | ||
| 2mg | 90.00 € | ||
| 5mg | 136.00 € | ||
| 10mg | 197.00 € | ||
| 25mg | 359.00 € | ||
| 50mg | 538.00 € | ||
| 100mg | 781.00 € | ||
| 200mg | 1,035.00 € | ||
| 1mL*10mM (DMSO) | 151.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
CHIR-98014
CAS:252935-94-7
CHIR-98014 (CT98014) is a selective GSK3 inhibitor; potentiate insulin activation of glucose transport and utilization …
Formula:
C20H17Cl2N9O2
Purity:
97.09% - 99.41%
Color and Shape:
Solid
Molecular weight:
486.31
Ref: TM-T2608
| 5mg | 74.00 € | ||
| 10mg | 106.00 € | ||
| 25mg | 214.00 € | ||
| 50mg | 349.00 € | ||
| 100mg | 560.00 € | ||
| 500mg | 1,170.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
BIO-acetoxime
CAS:667463-85-6
BIO-acetoxime (GSK-3 Inhibitor X) is a potent dual GSK3α/β inhibitor with IC50 of 10 nM, …
Formula:
C18H12BrN3O3
Purity:
97.28%
Color and Shape:
Solid
Molecular weight:
398.21
Ref: TM-T6787
| 1mg | 41.00 € | ||
| 2mg | 53.00 € | ||
| 5mg | 71.00 € | ||
| 10mg | 105.00 € | ||
| 25mg | 188.00 € | ||
| 50mg | 298.00 € | ||
| 100mg | 465.00 € | ||
| 200mg | 394.00 € | ||
| 1mL*10mM (DMSO) | 78.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
ASP4132
CAS:1640294-30-9
ASP4132 is an orally active AMPK activator (EC50 : 18 nM), has anti-cancer activity.
Formula:
C46H51F3N6O8S2
Purity:
99.26%
Color and Shape:
Solid
Molecular weight:
937.06
Ref: TM-T8432
| 1mg | 67.00 € | ||
| 2mg | 95.00 € | ||
| 5mg | 128.00 € | ||
| 10mg | 193.00 € | ||
| 25mg | 350.00 € | ||
| 50mg | 523.00 € | ||
| 100mg | 737.00 € | ||
| 1mL*10mM (DMSO) | 204.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
ALSTERPAULLONE
CAS:237430-03-4
Alsterpaullone is a Cyclin-Dependent Kinase Inhibitor, Mediated Toxicity in HeLa Cells Through Apoptosis-Inducing Effec
Formula:
C16H11N3O3
Purity:
99.39%
Color and Shape:
Solid
Molecular weight:
293.28
Ref: TM-T7426
| 1mg | 56.00 € | ||
| 5mg | 112.00 € | ||
| 10mg | 177.00 € | ||
| 25mg | 301.00 € | ||
| 50mg | 432.00 € | ||
| 100mg | 598.00 € | ||
| 200mg | 805.00 € | ||
| 1mL*10mM (DMSO) | 107.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Bikinin
CAS:188011-69-0
Bikinin (Abrasin), a potent inhibitor of plant GSK-3/Shaggy-like kinase, activates BR signaling downstream of the …
Formula:
C9H9BrN2O3
Purity:
100% - 99.91%
Color and Shape:
Solid
Molecular weight:
273.08
Ref: TM-T1965
| 10mg | 46.00 € | ||
| 25mg | 76.00 € | ||
| 50mg | 118.00 € | ||
| 100mg | 183.00 € | ||
| 200mg | 272.00 € | ||
| 500mg | 462.00 € | ||
| 1mL*10mM (DMSO) | 35.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
PI-3065
CAS:955977-50-1
PI-3065 is a novel potent and selective PI3K p110δ inhibitor.
Formula:
C27H31FN6OS
Purity:
98.39% - ≥95%
Color and Shape:
Solid
Molecular weight:
506.64
Ref: TM-T2083
| 1mg | 38.00 € | ||
| 5mg | 79.00 € | ||
| 10mg | 115.00 € | ||
| 25mg | 200.00 € | ||
| 50mg | 326.00 € | ||
| 100mg | 540.00 € | ||
| 500mg | 1,107.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Olmutinib
CAS:1802181-20-9
Olmutinib (BI1482694) is a Novel Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor
Formula:
C26H26N6O2S
Purity:
97.46%
Color and Shape:
Solid
Molecular weight:
486.59
Ref: TM-T8460
| 2mg | 36.00 € | ||
| 5mg | 56.00 € | ||
| 10mg | 91.00 € | ||
| 25mg | 129.00 € | ||
| 50mg | 181.00 € | ||
| 100mg | 277.00 € | ||
| 200mg | 454.00 € | ||
| 1mL*10mM (DMSO) | 63.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
WHI-P180
CAS:211555-08-7
WHI-P180 (Janex 3) is a potent EGFR and Cdk2 inhibitors with IC50 of 4.0 and …
Formula:
C16H15N3O3
Purity:
97.74%
Color and Shape:
Solid
Molecular weight:
297.31
Ref: TM-T2032
| 1mg | 46.00 € | ||
| 5mg | 87.00 € | ||
| 10mg | 131.00 € | ||
| 25mg | 215.00 € | ||
| 50mg | 321.00 € | ||
| 100mg | 463.00 € | ||
| 1mL*10mM (DMSO) | 87.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
HTH-01-015
CAS:1613724-42-7
HTH-01-015 is a selective NUAK1 inhibitor (IC50=100 nM).
Formula:
C26H28N8O
Purity:
98.1% - 99.08%
Color and Shape:
Solid
Molecular weight:
468.55
Ref: TM-T2374
| 1mg | 44.00 € | ||
| 2mg | 54.00 € | ||
| 5mg | 78.00 € | ||
| 10mg | 105.00 € | ||
| 25mg | 208.00 € | ||
| 50mg | 296.00 € | ||
| 100mg | 400.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
SB 415286
CAS:264218-23-7
SB 415286 is a potent GSK3α inhibitor with IC50/Ki of 78 nM/31 nM with equally …
Formula:
C16H10ClN3O5
Purity:
99.56%
Color and Shape:
Solid
Molecular weight:
359.72
Ref: TM-T6659
| 5mg | 48.00 € | ||
| 10mg | 70.00 € | ||
| 25mg | 126.00 € | ||
| 50mg | 201.00 € | ||
| 100mg | 328.00 € | ||
| 1mL*10mM (DMSO) | 51.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
PD158780
CAS:171179-06-9
PD 158780 blocks all ErbB receptors: EGFR, ErbB2-4, with IC50s: 8μM, 49-52 nM.
Formula:
C14H12BrN5
Purity:
98.81%
Color and Shape:
Solid
Molecular weight:
330.18
Ref: TM-T5410
| 1mg | 40.00 € | ||
| 5mg | 84.00 € | ||
| 10mg | 119.00 € | ||
| 25mg | 214.00 € | ||
| 50mg | 373.00 € | ||
| 100mg | 546.00 € | ||
| 1mL*10mM (DMSO) | 96.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
BpV(HOpic)
CAS:722494-26-0
BpV(HOpic) (bpV (HOpic)) is a potent inhibitor of PTEN (IC50 of 14 nM).
Formula:
C6H4K2NO8V
Purity:
99.86%
Color and Shape:
Solid
Molecular weight:
347.24
Ref: TM-T7953
| 1mg | 64.00 € | ||
| 2mg | 93.00 € | ||
| 5mg | 139.00 € | ||
| 10mg | 212.00 € | ||
| 25mg | 426.00 € | ||
| 50mg | 611.00 € | ||
| 100mg | 857.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
SU5204
CAS:186611-11-0
SU5204 (3-[(2-Ethoxyphenyl)methylidene]-1H-indol-2-one), an analogue of SU5025, pharmacologically inhibits VEGFR2(IC50s of 4 and 51.5 μM for …
Formula:
C17H15NO2
Purity:
99.5%
Color and Shape:
Solid
Molecular weight:
265.31
Ref: TM-T22431
| 5mg | 34.00 € | ||
| 10mg | 51.00 € | ||
| 25mg | 84.00 € | ||
| 50mg | 112.00 € | ||
| 100mg | 174.00 € | ||
| 200mg | 256.00 € | ||
| 1mL*10mM (DMSO) | 37.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
PP2
CAS:172889-27-9
PP2 (AG 1879,AGL 1879) is a effective inhibitor of Lck/Fyn (IC50:4/5 nM) , ~100-fold less …
Formula:
C15H16ClN5
Purity:
95.65%
Color and Shape:
White Solid
Molecular weight:
301.77
Ref: TM-T6266
| 2mg | 46.00 € | ||
| 5mg | 68.00 € | ||
| 10mg | 114.00 € | ||
| 25mg | 185.00 € | ||
| 50mg | 314.00 € | ||
| 100mg | 498.00 € | ||
| 200mg | 709.00 € | ||
| 1mL*10mM (DMSO) | 75.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Tyrphostin AG30
CAS:122520-79-0
Tyrphostin AG30 (AG30) (AG30) is a potent protein tyrosine kinases (PTK) inhibitor.
Formula:
C10H7NO4
Purity:
99.02%
Color and Shape:
Solid
Molecular weight:
205.17
Ref: TM-T7101
| 2mg | 46.00 € | ||
| 5mg | 69.00 € | ||
| 10mg | 86.00 € | ||
| 25mg | 172.00 € | ||
| 50mg | 301.00 € | ||
| 100mg | 500.00 € | ||
| 1mL*10mM (DMSO) | 52.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
