PI3K
PI3K inhibitors are compounds that block the activity of Phosphoinositide 3-Kinases (PI3Ks), a family of enzymes involved in a wide range of cellular processes, including growth, proliferation, survival, and metabolism. The PI3K/Akt/mTOR pathway is often dysregulated in cancer, making PI3K a key target for cancer therapy. PI3K inhibitors are critical tools for studying signal transduction, cancer biology, and the development of targeted therapies. At CymitQuimica, we provide a variety of PI3K inhibitors to support your research in cell signaling, oncology, and therapeutic development.
Found 235 products for "PI3K".
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Rigosertib sodium
CAS:Rigosertib sodium (ON-01910), a non-ATP-competitive inhibitor of PLK1(IC50=9 nM), exhibits 30-fold higher specificity activity over Plk2 and no effect on Plk3.Formula:C21H24NNaO8SPurity:98% - 99.37%Color and Shape:SolidMolecular weight:473.47Hederacolchiside A1
CAS:Hederacolchiside A1 exhibits anti-leishmanial and anticancer activities by disrupting cell membranes and inducing apoptosis via the PI3K/Akt/mTOR pathway.Formula:C47H76O16Purity:98.76% - 99.92%Color and Shape:SolidMolecular weight:897.1Ref: TM-T2P2806
1mg46.00€5mg114.00€1mL*10mM (DMSO)161.00€10mg167.00€25mg268.00€50mg408.00€100mg587.00€200mg825.00€iMDK
CAS:iMDK quarterhydrate, a PI3K inhibitor, blocks MDK growth factor and enhances NSCLC treatment with MEK inhibitors, sparing normal cells.Formula:C21H13FN2O2SPurity:99.99%Color and Shape:White SolidMolecular weight:376.4GNE-493
CAS:GNE-493 is potent, selective, and orally available PI3K and mTOR inhibitor with potential anticancer activity.IC50s of 3.4 nM, 12 nM, 16 nM, 16 nM and 32 nM forFormula:C17H20N6O2SPurity:98%Color and Shape:SolidMolecular weight:372.44TASP0415914
CAS:TASP0415914 is an orally potent inhibitor of phosphoinositide 3-kinase γ (PI3Kγ). TFormula:C13H17N5O3SPurity:98.14%Color and Shape:SolidMolecular weight:323.37Ref: TM-T7879
1mg52.00€5mg111.00€1mL*10mM (DMSO)127.00€10mg177.00€25mg299.00€50mg424.00€100mg587.00€200mg792.00€3-Methyladenine
CAS:3-Methyladenine (3-MA) is a PI3K inhibitor that selectively inhibits class IB PI3Kγ (IC50=60 μM) and class III VPS34 (IC50=25 μM).Formula:C6H7N5Purity:98% - 99.57%Color and Shape:White SolidMolecular weight:149.153SKI V
CAS:SKI V is a potent and noncompetitive non-lipid sphingosine kinase (SPHK; SK) inhibitor (GST-hSK,IC50 : 2 μM), and is a PI3K inhibitor(hPI3k,IC50 : 6 μM),Formula:C15H10O4Purity:98.78%Color and Shape:Yellow SolidMolecular weight:254.24Ref: TM-T8461
1mg87.00€5mg178.00€1mL*10mM (DMSO)203.00€10mg281.00€25mg485.00€50mg708.00€100mg1,044.00€NIH-12848
CAS:NIH-12848 is a putative inhibitor of phosphatidylinositol 5-phosphate 4-kinase γ (PI5P4Kγ) with an IC50 of 1 μM.Formula:C20H14F3N3SPurity:99.87% - 99.9%Color and Shape:SolidMolecular weight:385.41Ref: TM-T3556
2mg35.00€5mg51.00€1mL*10mM (DMSO)55.00€10mg75.00€25mg133.00€50mg225.00€100mg323.00€200mg447.00€BGT226
CAS:BGT226 (NVP-BGT226) is a novel dual PI3K / mTOR inhibitor, it acts on PI3K α/β/γ with IC50 of 4 nM / 63 nM / 38 nM, respectively.Formula:C28H25F3N6O2Purity:95.74% - 99.78%Color and Shape:White SolidMolecular weight:534.53Ref: TM-T6072L
1mg47.00€2mg62.00€5mg92.00€1mL*10mM (DMSO)107.00€10mg147.00€25mg295.00€50mg485.00€100mg737.00€AS-252424
CAS:AS-252424 is a potent and selective inhibitor of PI3Kγ with IC50 of 33 nM; >10 fold selectivity for PI3Kγ versus PI3Kα.Formula:C14H8FNO4SPurity:99.06% - 99.09%Color and Shape:Orange SolidMolecular weight:305.28Ref: TM-T6208
1mg37.00€2mg52.00€5mg77.00€1mL*10mM (DMSO)84.00€10mg128.00€25mg205.00€50mg309.00€100mg447.00€500mg973.00€Fimepinostat
CAS:Fimepinostat (CUDC 907) is an orally bioavailable inhibitor of both PI3K class I and pan-HDAC enzymes, with potential antineoplastic activity.Formula:C23H24N8O4SPurity:98.27% - 99.87%Color and Shape:SolidMolecular weight:508.55Ref: TM-T2078
2mg44.00€5mg66.00€1mL*10mM (DMSO)74.00€10mg92.00€25mg172.00€50mg295.00€100mg485.00€500mg1,035.00€Idelalisib
CAS:Idelalisib (GS-1101) is a small molecule inhibitor of the PI3K catalytic subunit p110δ (IC50: 2.5 nM).Formula:C22H18FN7OPurity:98% - 99.39%Color and Shape:White SolidMolecular weight:415.42Ref: TM-T1894
5mg34.00€1mL*10mM (DMSO)39.00€10mg48.00€25mg71.00€50mg88.00€100mg103.00€200mg133.00€500mg213.00€1,3-Dicaffeoylquinic acid
CAS:1,3-Dicaffeoylquinic acid (CYNARIN) is a natural product. It shows antioxidant and choleretic properties and is a potential immunosuppressive agent.Formula:C25H24O12Purity:98% - 98.81%Color and Shape:SolidMolecular weight:516.45Ref: TM-T5736
1mg37.00€5mg71.00€10mg90.00€1mL*10mM (DMSO)103.00€25mg147.00€50mg208.00€100mg309.00€200mg447.00€PIK-294
CAS:PIK-294 is a excellently specific p110δ inhibitor(IC50=10 nM).Formula:C28H23N7O2Purity:97.22% - >99.99%Color and Shape:SolidMolecular weight:489.53PF-4989216
CAS:PF-4989216 is a potent and selective PI3K inhibitor with IC50 of 2 nM, 142 nM, 65 nM, 1 nM, and 110 nM for p110α, p110β, p110γ, p110δ, and VPS34, respectively.Formula:C18H13FN6OSPurity:99.85%Color and Shape:SolidMolecular weight:380.4Ref: TM-T6938
2mg37.00€5mg62.00€1mL*10mM (DMSO)64.00€10mg96.00€25mg177.00€50mg311.00€100mg376.00€200mg535.00€Arnicolide D
CAS:Arnicolide D is a sesquiterpene lactone.Formula:C19H24O5Purity:96.66% - 99.93%Color and Shape:White SolidMolecular weight:332.39Omipalisib
CAS:Omipalisib (GSK2126458) is a small-molecule pyridylsulfonamide inhibitor of phosphatidylinositol 3-kinase (PI3K) with potential antineoplastic activity.Formula:C25H17F2N5O3SPurity:98% - 99.8%Color and Shape:Yellow SolidMolecular weight:505.51-Deoxynojirimycin
CAS:1-Deoxynojirimycin (Moranoline) is a potent α-glucosidase inhibitor, suppressing postprandial blood glucose, thereby possibly preventing diabetes mellitus.Formula:C6H13NO4Purity:99.65% - 99.98%Color and Shape:SolidMolecular weight:163.17Ref: TM-T3675
2mg43.00€1mL*10mM (DMSO)57.00€5mg58.00€10mg74.00€25mg140.00€50mg248.00€100mg321.00€500mg773.00€1-Deoxynojirimycin hydrochloride
CAS:1-Deoxynojirimycin hydrochloride (Moranoline) is a potent and selective inhibitor of alpha-glucosidase, most commonly found in mulberry leaves.Formula:C6H14ClNO4Purity:99.88%Color and Shape:SolidMolecular weight:199.633Bimiralisib
CAS:Bimiralisib (PI3K-IN-2) is an orally bioavailable pan inhibitor of PI3K and inhibitor of the mTOR, with potential antineoplastic activity.Formula:C17H20F3N7O2Purity:97.58% - 98.92%Color and Shape:SolidMolecular weight:411.38Ref: TM-T2265
10mgTo inquire25mgTo inquire50mgTo inquire100mgTo inquire1mg34.00€5mg75.00€1mL*10mM (DMSO)84.00€
